1
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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.
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Nat Genet
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2006
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13.63
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2
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Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.
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Genome Res
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2010
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6.03
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3
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Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer.
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Nature
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2010
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4.01
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4
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A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
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Nat Genet
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2010
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3.86
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5
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FBXW7/hCDC4 is a general tumor suppressor in human cancer.
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Cancer Res
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2007
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3.79
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6
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An epigenetic signature in peripheral blood predicts active ovarian cancer.
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PLoS One
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2009
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3.33
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7
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Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies.
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Bioinformatics
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2011
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2.91
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8
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hCDC4 gene mutations in endometrial cancer.
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Cancer Res
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2002
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2.36
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9
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DNA methylation in serum of breast cancer patients: an independent prognostic marker.
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Cancer Res
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2003
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2.14
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10
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Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer.
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Cancer Res
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2006
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1.99
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11
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Methylation changes in faecal DNA: a marker for colorectal cancer screening?
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Lancet
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2004
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1.80
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12
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Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip.
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Methods
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2010
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1.71
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13
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Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation.
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Genome Med
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2012
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1.65
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14
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Circulating tumor-specific DNA: a marker for monitoring efficacy of adjuvant therapy in cancer patients.
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Cancer Res
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2005
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1.62
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15
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Hypomethylation and hypermethylation of DNA in Wilms tumors.
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Oncogene
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2002
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1.59
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16
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DNA hypomethylation is prevalent even in low-grade breast cancers.
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Cancer Biol Ther
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2004
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1.53
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17
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Differential variability improves the identification of cancer risk markers in DNA methylation studies profiling precursor cancer lesions.
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Bioinformatics
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2012
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1.51
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18
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Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer.
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Cancer Res
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2004
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1.45
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19
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HOXA11 DNA methylation--a novel prognostic biomarker in ovarian cancer.
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Int J Cancer
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2008
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1.44
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20
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The dynamics and prognostic potential of DNA methylation changes at stem cell gene loci in women's cancer.
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PLoS Genet
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2012
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1.33
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21
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A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform.
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BMC Bioinformatics
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2012
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1.26
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22
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Recruitment of newly diagnosed ovarian cancer patients proved challenging in a multicentre biobanking study.
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J Clin Epidemiol
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2010
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1.18
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23
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Cellular network entropy as the energy potential in Waddington's differentiation landscape.
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Sci Rep
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2013
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1.12
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24
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Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins.
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Proc Natl Acad Sci U S A
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2011
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1.11
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25
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Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development.
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PLoS Med
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2013
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1.10
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26
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DNA methylation in serum and tumors of cervical cancer patients.
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Clin Cancer Res
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2004
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1.06
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27
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Prognostic DNA methylation marker in serum of cancer patients.
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Ann N Y Acad Sci
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2004
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1.06
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28
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Methylation status and expression of human telomerase reverse transcriptase in ovarian and cervical cancer.
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Gynecol Oncol
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2004
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1.06
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29
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Methylated DNA as a possible screening marker for neoplastic disease in several body fluids.
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Expert Rev Mol Diagn
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2003
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1.06
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30
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DNA methylation analysis in liquid-based cytology for cervical cancer screening.
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Int J Cancer
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2009
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1.04
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31
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Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer.
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Breast Cancer Res
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2010
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1.01
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32
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Underlying mechanisms of ovarian cancer risk reduction after tubal ligation.
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Acta Obstet Gynecol Scand
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2011
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0.99
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33
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Methylated DNA collected by tampons--a new tool to detect endometrial cancer.
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Cancer Epidemiol Biomarkers Prev
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2004
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0.99
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34
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Cyclin E dysregulation and chromosomal instability in endometrial cancer.
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Oncogene
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2004
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0.99
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35
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CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer.
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EMBO Mol Med
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2013
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0.99
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36
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Analysis of methylated genes in peritoneal fluids of ovarian cancer patients: a new prognostic tool.
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Clin Chem
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2004
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0.98
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37
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Analysis of aberrant DNA methylation and human papillomavirus DNA in cervicovaginal specimens to detect invasive cervical cancer and its precursors.
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Clin Cancer Res
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2004
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0.96
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38
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Loss of imprinting and aberrant methylation of IGF2 in placentas from pregnancies complicated with fetal growth restriction.
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Int J Mol Med
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2011
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0.96
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39
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CDH1 and CDH13 methylation in serum is an independent prognostic marker in cervical cancer patients.
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Int J Cancer
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2004
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0.95
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40
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Distinctive topology of age-associated epigenetic drift in the human interactome.
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Proc Natl Acad Sci U S A
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2013
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0.94
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41
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Toll-like receptor 9 expression in breast and ovarian cancer is associated with poorly differentiated tumors.
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Cancer Sci
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2010
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0.92
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42
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Detection of low molecular weight derivatives of cyclin E1 is a function of cyclin E1 protein levels in breast cancer.
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Cancer Res
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2006
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0.92
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43
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DNA methylation changes in sera of women in early pregnancy are similar to those in advanced breast cancer patients.
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Clin Chem
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2004
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0.91
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44
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Corruption of the intra-gene DNA methylation architecture is a hallmark of cancer.
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PLoS One
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2013
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0.88
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45
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Methylated NEUROD1 promoter is a marker for chemosensitivity in breast cancer.
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Clin Cancer Res
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2008
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0.87
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46
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DNA methylation markers for early detection of women's cancer: promise and challenges.
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Epigenomics
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2014
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0.87
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47
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Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.
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PLoS One
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2011
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0.87
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48
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Association of serum sex steroid receptor bioactivity and sex steroid hormones with breast cancer risk in postmenopausal women.
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Endocr Relat Cancer
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2012
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0.87
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49
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A DNA methylation pattern similar to normal tissue is associated with better prognosis in human cervical cancer.
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Cancer Lett
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2004
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0.85
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50
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Pregnancy-associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer.
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J Pathol
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2014
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0.84
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51
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GALR1 methylation in vaginal swabs is highly accurate in identifying women with endometrial cancer.
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Int J Gynecol Cancer
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2013
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0.84
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52
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A prospective validation of the IOTA logistic regression models (LR1 and LR2) in comparison to subjective pattern recognition for the diagnosis of ovarian cancer.
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Int J Gynecol Cancer
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2013
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0.83
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53
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Development and validation of a method for profiling post-translational modification activities using protein microarrays.
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PLoS One
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2010
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0.83
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54
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DNA methylation of polycomb group target genes in cores taken from breast cancer centre and periphery.
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Breast Cancer Res Treat
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2009
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0.82
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55
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Emerging promise of epigenetics and DNA methylation for the diagnosis and management of women's cancers.
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Epigenomics
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2010
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0.82
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56
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Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.
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Oncotarget
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2014
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0.82
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57
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Noninvasive nutritional management of ovarian cancer patients: beyond intestinal obstruction.
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Int J Gynecol Cancer
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2012
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0.80
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58
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Pregnancy as a tissue expander in the correction of a scar deformity.
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Am J Obstet Gynecol
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2004
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0.80
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59
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A randomised controlled trial comparing surgical intervention rates between two protocols for the management of asymptomatic adnexal tumours in postmenopausal women.
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BMJ Open
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2012
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0.79
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60
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PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer.
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Cancer Res
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2014
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0.78
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61
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5-methylcytosine--the fifth base of DNA: the fifth wheel on a car or a highly promising diagnostic and therapeutic target in cancer?
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Dis Markers
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2007
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0.76
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62
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Fooled by the film: delayed diagnosis of incarcerated small-bowel hernia after laparoscopic surgery for endometrial cancer.
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Int J Gynecol Cancer
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0.75
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Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer.
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Oncology
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0.75
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