Published in CMAJ on July 04, 2006
Depression and type 2 diabetes over the lifespan: a meta-analysis. Diabetes Care (2008) 7.27
Examining a bidirectional association between depressive symptoms and diabetes. JAMA (2008) 6.83
Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis. Diabetologia (2010) 2.50
Hyperglycemia, type 2 diabetes, and depressive symptoms: the British Whitehall II study. Diabetes Care (2009) 1.10
Population-based cohort analyses of the bidirectional relationship between type 2 diabetes and depression. Diabetes Care (2012) 1.03
Prevalence of depressive symptoms among non insulin treated Greek type 2 diabetic subjects. BMC Res Notes (2008) 0.94
Metabolic syndrome and depressive symptoms among Japanese men and women. Environ Health Prev Med (2011) 0.91
A study of association of depressive symptoms among the type 2 diabetic outpatients presenting to a tertiary care hospital. Indian J Psychol Med (2012) 0.86
Association of depression and its relation with complications in newly diagnosed type 2 diabetes. Indian J Endocrinol Metab (2012) 0.84
Incidence and risk of depression associated with diabetes in adults: evidence from longitudinal studies. Community Ment Health J (2014) 0.83
Increased risk of affective disorders in type 2 diabetes is minimized by sulfonylurea and metformin combination: a population-based cohort study. BMC Med (2012) 0.83
Prevalence and Impact of Anxiety and Depression on Type 2 Diabetes in Tunisian Patients over Sixty Years Old. Depress Res Treat (2013) 0.81
Increased health burden associated with comorbid depression in older Brazilians with diabetes. J Affect Disord (2011) 0.81
Risk for high depressive symptoms in diagnosed and previously undetected diabetes: 5-year follow-up results of the Heinz Nixdorf Recall study. PLoS One (2013) 0.76
Quantitative assessment of the bidirectional relationships between diabetes and depression. Oncotarget (2017) 0.75
Incidence of Depression and Associated Factors in Patients With Type 2 Diabetes in Quebec, Canada: A Population-Based Cohort Study. Medicine (Baltimore) (2016) 0.75
Low risk of depression in diabetes? Would that it were so. CMAJ (2006) 0.75
Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med (1998) 25.66
Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med (2003) 20.06
The prevalence of comorbid depression in adults with diabetes: a meta-analysis. Diabetes Care (2001) 15.36
Diabetes in Ontario: determination of prevalence and incidence using a validated administrative data algorithm. Diabetes Care (2002) 10.24
Depression following myocardial infarction. Impact on 6-month survival. JAMA (1993) 8.64
Depression and poor glycemic control: a meta-analytic review of the literature. Diabetes Care (2000) 8.63
Association of depression and diabetes complications: a meta-analysis. Psychosom Med (2001) 8.30
Depression and diabetes: impact of depressive symptoms on adherence, function, and costs. Arch Intern Med (2000) 7.79
Relationship of depression and diabetes self-care, medication adherence, and preventive care. Diabetes Care (2004) 6.09
Comorbid depression is associated with increased health care use and expenditures in individuals with diabetes. Diabetes Care (2002) 5.60
Depression predicts increased incidence of adverse health outcomes in older Mexican Americans with type 2 diabetes. Diabetes Care (2003) 4.92
Diabetes and decline in heart disease mortality in US adults. JAMA (1999) 4.49
The relationship of depressive symptoms to symptom reporting, self-care and glucose control in diabetes. Gen Hosp Psychiatry (2003) 3.13
Depressive symptoms and mortality among persons with and without diabetes. Am J Epidemiol (2005) 2.84
Depression and risk for onset of type II diabetes. A prospective population-based study. Diabetes Care (1996) 2.78
Prospective study of social and other risk factors for incidence of type 2 diabetes in the Whitehall II study. Arch Intern Med (2004) 2.69
Evidence of suboptimal management of cardiovascular risk in patients with type 2 diabetes mellitus and symptomatic atherosclerosis. CMAJ (2004) 2.55
Depressive symptoms, insulin resistance, and risk of diabetes in women at midlife. Diabetes Care (2004) 2.55
Incidence and prevalence of diabetes in Manitoba, 1986-1991. Diabetes Care (1996) 2.30
Conspicuous consumption: characterizing high users of physician services in one Canadian province. J Health Serv Res Policy (2003) 2.28
Prevalence of depression in adults with diabetes. An epidemiological evaluation. Diabetes Care (1993) 2.13
Depressive symptoms and the risk of type 2 diabetes: the Atherosclerosis Risk in Communities study. Diabetes Care (2004) 2.03
Depression in adults with diabetes. Diabetes Care (1992) 1.99
Long-term risk for depressive symptoms after a medical diagnosis. Arch Intern Med (2005) 1.97
Symptoms of depression as a risk factor for incident diabetes: findings from the National Health and Nutrition Examination Epidemiologic Follow-up Study, 1971-1992. Am J Epidemiol (2003) 1.95
The impact of poststroke depression on recovery in activities of daily living over a 2-year follow-up. Arch Neurol (1990) 1.83
Depressive symptoms and risk of type 2 diabetes in women. Diabetes Care (2004) 1.80
Depressive symptoms and occurrence of type 2 diabetes among Japanese men. Diabetes Care (1999) 1.78
Diagnosis and management of depression in primary care: a clinical update and review. CMAJ (2002) 1.64
A prospective study of Type 2 diabetes and depressive symptoms in the elderly: the Rancho Bernardo Study. Diabet Med (2004) 1.58
Unadjusted and adjusted prevalence of diagnosed depression in type 2 diabetes. Diabetes Care (2003) 1.46
The longitudinal relation between chronic diseases and depression in older persons in the community: the Longitudinal Aging Study Amsterdam. J Clin Epidemiol (2004) 1.45
Depression and diabetes: a large population-based study of sociodemographic, lifestyle, and clinical factors associated with depression in type 1 and type 2 diabetes. Diabetes Care (2005) 1.44
Effects of depression on work loss and disability bed days in individuals with diabetes. Diabetes Care (2004) 1.40
History of depression increases risk of type 2 diabetes in younger adults. Diabetes Care (2005) 1.35
Prevalence and costs of major depression among elderly claimants with diabetes. Diabetes Care (2003) 1.27
Depressive symptoms and the risk of type 2 diabetes mellitus in a US sample. Diabetes Metab Res Rev (2003) 1.18
Is depression related to subsequent diabetes mellitus? Acta Psychiatr Scand (2004) 1.14
Assessing the Saskatchewan database for outcomes research studies of depression and its treatment. J Clin Epidemiol (2000) 1.11
Clinical guidelines for the treatment of depressive disorders, I. Definitions, prevalence, and health burden. Can J Psychiatry (2001) 0.96
The Canadian Adverse Events Study: the incidence of adverse events among hospital patients in Canada. CMAJ (2004) 21.24
Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana. N Engl J Med (2012) 20.03
US valuation of the EQ-5D health states: development and testing of the D1 valuation model. Med Care (2005) 9.89
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin. Diabetes Care (2006) 7.99
A meta-analysis of the association between adherence to drug therapy and mortality. BMJ (2006) 7.79
Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovir. PLoS Med (2008) 7.46
Improved clinical outcomes associated with metformin in patients with diabetes and heart failure. Diabetes Care (2005) 4.78
Drug treatments for obesity: orlistat, sibutramine, and rimonabant. Lancet (2007) 4.47
Benefits and harms of antidiabetic agents in patients with diabetes and heart failure: systematic review. BMJ (2007) 3.95
New evidence for stroke prevention: scientific review. JAMA (2002) 3.70
Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. J Biol Chem (2003) 3.61
Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J Neurosci (2003) 3.54
Self-reported health status of the general adult U.S. population as assessed by the EQ-5D and Health Utilities Index. Med Care (2005) 3.46
Physical activity level and health-related quality of life in the general adult population: a systematic review. Prev Med (2007) 3.45
Effect of pay for performance on the management and outcomes of hypertension in the United Kingdom: interrupted time series study. BMJ (2011) 3.29
Association between glycemic control and adverse outcomes in people with diabetes mellitus and chronic kidney disease: a population-based cohort study. Arch Intern Med (2011) 3.13
Decreased mortality associated with the use of metformin compared with sulfonylurea monotherapy in type 2 diabetes. Diabetes Care (2002) 3.12
Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis. JAMA (2011) 3.08
An important role of Nrf2-ARE pathway in the cellular defense mechanism. J Biochem Mol Biol (2004) 2.74
Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes. Mol Cancer Ther (2007) 2.71
Prevalence of transmitted drug resistance associated mutations and HIV-1 subtypes in new HIV-1 diagnoses, U.S.-2006. AIDS (2010) 2.62
Nrf2, a multi-organ protector? FASEB J (2005) 2.61
Differential gene expression patterns revealed by oligonucleotide versus long cDNA arrays. Toxicol Sci (2002) 2.61
Evidence of suboptimal management of cardiovascular risk in patients with type 2 diabetes mellitus and symptomatic atherosclerosis. CMAJ (2004) 2.55
Costs and consequences of direct-to-consumer advertising for clopidogrel in Medicaid. Arch Intern Med (2009) 2.54
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte. Proc Natl Acad Sci U S A (2009) 2.54
A randomized trial of the effect of community pharmacist intervention on cholesterol risk management: the Study of Cardiovascular Risk Intervention by Pharmacists (SCRIP). Arch Intern Med (2002) 2.49
The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease. Antioxid Redox Signal (2009) 2.49
A controlled trial to increase detection and treatment of osteoporosis in older patients with a wrist fracture. Ann Intern Med (2004) 2.48
Development and initial validation of a risk score for predicting in-hospital and 1-year mortality in patients with hip fractures. J Bone Miner Res (2004) 2.47
Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis. J Neurosci (2008) 2.34
NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons. J Biol Chem (2003) 2.33
Mortality after incident cancer in people with and without type 2 diabetes: impact of metformin on survival. Diabetes Care (2012) 2.32
Best practices for elderly hip fracture patients. A systematic overview of the evidence. J Gen Intern Med (2005) 2.27
Viral infection in adults hospitalized with community-acquired pneumonia: prevalence, pathogens, and presentation. Chest (2008) 2.26
The relation between hyperglycemia and outcomes in 2,471 patients admitted to the hospital with community-acquired pneumonia. Diabetes Care (2005) 2.24
Stroke: strategies for primary prevention. Am Fam Physician (2003) 2.19
Low frequency of treatment of osteoporosis among postmenopausal women following a fracture. Arch Intern Med (2003) 2.19
Core competencies in the science and practice of knowledge translation: description of a Canadian strategic training initiative. Implement Sci (2011) 2.09
Validity and reliability of the Edmonton Frail Scale. Age Ageing (2006) 2.08
Effect of illicit direct to consumer advertising on use of etanercept, mometasone, and tegaserod in Canada: controlled longitudinal study. BMJ (2008) 2.01
A systematic review of drug therapy to delay or prevent type 2 diabetes. Diabetes Care (2005) 2.01
Heart failure is a risk factor for orthopedic fracture: a population-based analysis of 16,294 patients. Circulation (2008) 1.98
Impact of cancer on adherence to glucose-lowering drug treatment in individuals with diabetes. Diabetologia (2015) 1.96
A multicenter disease management program for hospitalized patients with heart failure. J Card Fail (2004) 1.90
Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription. Proc Natl Acad Sci U S A (2004) 1.89
Mortality reduction with influenza vaccine in patients with pneumonia outside "flu" season: pleiotropic benefits or residual confounding? Am J Respir Crit Care Med (2008) 1.85
Dose-response relation between sulfonylurea drugs and mortality in type 2 diabetes mellitus: a population-based cohort study. CMAJ (2006) 1.80
Multimorbidity prevalence and patterns across socioeconomic determinants: a cross-sectional survey. BMC Public Health (2012) 1.79
The impact of selecting a high hemoglobin target level on health-related quality of life for patients with chronic kidney disease: a systematic review and meta-analysis. Arch Intern Med (2009) 1.77
Health-related quality of life deficits associated with diabetes and comorbidities in a Canadian National Population Health Survey. Qual Life Res (2005) 1.76
Effect of pneumococcal vaccination in hospitalized adults with community-acquired pneumonia. Arch Intern Med (2007) 1.76
Enhancing primary care for complex patients. Demonstration project using multidisciplinary teams. Can Fam Physician (2004) 1.74
Developmental exposure to methylmercury alters learning and induces depression-like behavior in male mice. Toxicol Sci (2007) 1.72
Hypertension management: the care gap between clinical guidelines and clinical practice. Am J Manag Care (2004) 1.66
Agreement between patient and proxy assessments of health-related quality of life after stroke using the EQ-5D and Health Utilities Index. Stroke (2004) 1.66
Long-term association between frailty and health-related quality of life among survivors of critical illness: a prospective multicenter cohort study. Crit Care Med (2015) 1.62
Responsiveness of generic health-related quality of life measures in stroke. Qual Life Res (2005) 1.62
Weight loss required by the severely obese to achieve clinically important differences in health-related quality of life: two-year prospective cohort study. BMC Med (2014) 1.61
How evidence-based are the recommendations in evidence-based guidelines? PLoS Med (2007) 1.60
Macrolides and mortality in critically ill patients with community-acquired pneumonia: a systematic review and meta-analysis. Crit Care Med (2014) 1.60
Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice. Physiol Genomics (2004) 1.60
Type of antidepressant therapy and risk of type 2 diabetes in people with depression. Diabetes Res Clin Pract (2007) 1.59
The Nrf2-ARE cytoprotective pathway in astrocytes. Expert Rev Mol Med (2009) 1.57
The Enhancing Secondary Prevention in Coronary Artery Disease trial. CMAJ (2009) 1.57
Relationship Among Body Fat Percentage, Body Mass Index, and All-Cause Mortality: A Cohort Study. Ann Intern Med (2016) 1.56
Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways. J Neurosci (2002) 1.51
Use of thiazolidinediones and the risk of bladder cancer among people with type 2 diabetes: a meta-analysis. CMAJ (2012) 1.50
Health literacy and health outcomes in diabetes: a systematic review. J Gen Intern Med (2012) 1.49
The efficacy and safety of intensive statin therapy: a meta-analysis of randomized trials. CMAJ (2008) 1.48
Radiologic and patient-reported functional outcomes in an elderly cohort with conservatively treated distal radius fractures. J Hand Surg Am (2004) 1.48
The cost of major comorbidity in people with diabetes mellitus. CMAJ (2003) 1.47
Compliance with clinical practice guidelines for type 2 diabetes in rural patients: treatment gaps and opportunities for improvement. Pharmacotherapy (2003) 1.47
Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis. Diabetologia (2014) 1.46
Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing. Mol Cell Biol (2006) 1.45
A genomic screen for activators of the antioxidant response element. Proc Natl Acad Sci U S A (2007) 1.44
Atenolol as initial antihypertensive therapy: an observational study comparing first-line agents. J Hypertens (2007) 1.44
The effectiveness of beta-blockers after myocardial infarction in patients with type 2 diabetes. Diabetes Care (2005) 1.43
Nrf2-mediated protection against 6-hydroxydopamine. Brain Res (2007) 1.42
Similar outcomes among general medicine patients discharged on weekends. J Hosp Med (2014) 1.42
Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells. J Biol Chem (2001) 1.39
Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia. J Neurochem (2009) 1.39
Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia. Proc Natl Acad Sci U S A (2004) 1.39