Published in Immunol Rev on June 01, 2006
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity (2007) 12.98
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J Exp Med (2008) 5.71
Initial T cell receptor transgenic cell precursor frequency dictates critical aspects of the CD8(+) T cell response to infection. Immunity (2007) 4.92
Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs. J Exp Med (2009) 3.01
Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs. J Exp Med (2008) 2.55
Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection. Proc Natl Acad Sci U S A (2007) 2.48
Generation of effector CD8+ T cells and their conversion to memory T cells. Immunol Rev (2010) 1.85
Tracking the total CD8 T cell response to infection reveals substantial discordance in magnitude and kinetics between inbred and outbred hosts. J Immunol (2009) 1.68
The metabolic life and times of a T-cell. Immunol Rev (2010) 1.57
Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A. J Virol (2008) 1.52
A default pathway of memory CD8 T cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation. J Immunol (2009) 1.50
Gene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis. J Clin Invest (2011) 1.47
Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity. Proc Natl Acad Sci U S A (2009) 1.44
An IFN-gamma-IL-18 signaling loop accelerates memory CD8+ T cell proliferation. PLoS One (2008) 1.35
Surviving the crash: transitioning from effector to memory CD8+ T cell. Semin Immunol (2009) 1.31
Critical role for IL-21 in both primary and memory anti-viral CD8+ T-cell responses. Eur J Immunol (2010) 1.27
Memory generation and maintenance of CD8+ T cell function during viral persistence. J Immunol (2007) 1.23
The role of IL-6 in inhibition of lymphocyte apoptosis by mesenchymal stem cells. Biochem Biophys Res Commun (2007) 1.21
Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly. Proc Natl Acad Sci U S A (2010) 1.21
Population dynamics of naive and memory CD8 T cell responses after antigen stimulations in vivo. J Immunol (2011) 1.18
Secondary CD8+ T-cell responses are controlled by systemic inflammation. Eur J Immunol (2011) 1.16
IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo. J Exp Med (2013) 1.16
Modulating numbers and phenotype of CD8+ T cells in secondary immune responses. Eur J Immunol (2010) 1.11
Location rather than CD62L phenotype is critical in the early establishment of influenza-specific CD8+ T cell memory. Proc Natl Acad Sci U S A (2007) 1.10
Maturation-dependent licensing of naive T cells for rapid TNF production. PLoS One (2010) 1.09
Diet-induced obesity in mice reduces the maintenance of influenza-specific CD8+ memory T cells. J Nutr (2010) 1.04
Naive, effector and memory CD8 T-cell trafficking: parallels and distinctions. Immunotherapy (2011) 1.03
Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cells. PLoS One (2011) 1.03
Division-linked generation of death-intermediates regulates the numerical stability of memory CD8 T cells. Proc Natl Acad Sci U S A (2012) 1.01
Improving the MVA vaccine potential by deleting the viral gene coding for the IL-18 binding protein. PLoS One (2012) 1.01
Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo. Blood (2010) 1.01
Intracellular events and cell fate in filovirus infection. Viruses (2011) 1.01
High-throughput gene expression profiling of memory differentiation in primary human T cells. BMC Immunol (2008) 0.99
Duration of antigen expression in vivo following DNA immunization modifies the magnitude, contraction, and secondary responses of CD8+ T lymphocytes. J Immunol (2007) 0.98
Concurrent generation of effector and central memory CD8 T cells during vaccinia virus infection. PLoS One (2008) 0.98
A unified framework of immunological and epidemiological dynamics for the spread of viral infections in a simple network-based population. Theor Biol Med Model (2007) 0.97
Positive and negative regulation of cellular immune responses in physiologic conditions and diseases. Clin Dev Immunol (2012) 0.95
Polymicrobial sepsis alters antigen-dependent and -independent memory CD8 T cell functions. J Immunol (2014) 0.95
The early kinetics of cytomegalovirus-specific CD8+ T-cell responses are not affected by antigen load or the absence of perforin or gamma interferon. J Virol (2008) 0.92
ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation. J Immunol (2013) 0.91
T-cell-mediated immunity and the role of TRAIL in sepsis-induced immunosuppression. Crit Rev Immunol (2013) 0.91
Increased memory conversion of naïve CD8 T cells activated during late phases of acute virus infection due to decreased cumulative antigen exposure. PLoS One (2011) 0.91
Differential role of "Signal 3" inflammatory cytokines in regulating CD8 T cell expansion and differentiation in vivo. Front Immunol (2011) 0.89
The roles of IL-12 and IL-23 in CD8+ T cell-mediated immunity against Listeria monocytogenes: Insights from a DC vaccination model. Cell Immunol (2010) 0.86
Viral vector vaccines make memory T cells against malaria. Immunology (2007) 0.86
Protective and pathologic roles of the immune response to mouse hepatitis virus type 1: implications for severe acute respiratory syndrome. J Virol (2009) 0.85
The impact of pre-existing memory on differentiation of newly recruited naive CD8 T cells. J Immunol (2011) 0.84
NK1.1+ CD8+ T cells escape TGF-β control and contribute to early microbial pathogen response. Nat Commun (2014) 0.82
Cutting edge: Expression of FcγRIIB tempers memory CD8 T cell function in vivo. J Immunol (2013) 0.81
The longevity of memory CD8 T cell responses after repetitive antigen stimulations. J Immunol (2014) 0.81
Epitope specificity of memory CD8+ T cells dictates vaccination-induced mortality in LCMV-infected perforin-deficient mice. Eur J Immunol (2012) 0.81
Regulatory T Cells Modulate DNA Vaccine Immunogenicity at Early Time via Functional CD4(+) T Cells and Antigen Duration. Front Immunol (2015) 0.81
Attrition of memory CD8 T cells during sepsis requires LFA-1. J Leukoc Biol (2016) 0.80
Manipulating Memory CD8 T Cell Numbers by Timed Enhancement of IL-2 Signals. J Immunol (2016) 0.80
T cell epitope specificity and pathogenesis of mouse hepatitis virus-1-induced disease in susceptible and resistant hosts. J Immunol (2010) 0.79
Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates. Sci Rep (2016) 0.77
Enhancement of CD8(+) T-cell memory by removal of a vaccinia virus nuclear factor-κB inhibitor. Immunology (2015) 0.77
Clinical and Experimental Sepsis Impairs CD8 T-Cell-Mediated Immunity. Crit Rev Immunol (2016) 0.76
Induction of CD4-independent E7-specific CD8+ memory response by heat shock fusion protein. Clin Vaccine Immunol (2007) 0.76
Listeria monocytogenes: a model pathogen to study antigen-specific memory CD8 T cell responses. Semin Immunopathol (2015) 0.76
The Timing of Stimulation and IL-2 Signaling Regulate Secondary CD8 T Cell Responses. PLoS Pathog (2015) 0.76
Antiapoptotic Role for Lifeguard in T Cell Mediated Immune Response. PLoS One (2015) 0.75
The Role of Cytokines and Chemokines in Filovirus Infection. Viruses (2015) 0.75
Temporary CXCR3 and CCR5 antagonism following vaccination enhances memory CD8 T cell immune responses. Mol Med (2016) 0.75
Illuminating the petite picture of T cell memory responses to Listeria monocytogenes. Biomed Res Int (2013) 0.75
On the Role of CD8(+) T Cells in Determining Recovery Time from Influenza Virus Infection. Front Immunol (2016) 0.75
Programmed contraction of CD8(+) T cells after infection. Nat Immunol (2002) 5.16
Initial T cell receptor transgenic cell precursor frequency dictates critical aspects of the CD8(+) T cell response to infection. Immunity (2007) 4.92
Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination. Nat Med (2005) 4.45
Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1. Immunity (2010) 3.49
CD8+ T cell contraction is controlled by early inflammation. Nat Immunol (2004) 3.13
Secondary memory CD8+ T cells are more protective but slower to acquire a central-memory phenotype. J Exp Med (2006) 2.80
Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria. Proc Natl Acad Sci U S A (2008) 2.62
Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection. Nat Immunol (2011) 2.54
Inflaming the CD8+ T cell response. Immunity (2006) 2.44
Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation. Immunity (2010) 2.38
Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection. J Immunol (2014) 1.96
Regulation of CD8+ T cells undergoing primary and secondary responses to infection in the same host. J Immunol (2003) 1.93
Neutrophil involvement in cross-priming CD8+ T cell responses to bacterial antigens. J Immunol (2004) 1.83
Tracking the total CD8 T cell response to infection reveals substantial discordance in magnitude and kinetics between inbred and outbred hosts. J Immunol (2009) 1.68
Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites. PLoS Pathog (2010) 1.64
Manipulating the rate of memory CD8+ T cell generation after acute infection. J Immunol (2007) 1.63
Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites. Cell Host Microbe (2011) 1.61
Dynamic regulation of IFN-gamma signaling in antigen-specific CD8+ T cells responding to infection. J Immunol (2005) 1.58
Constitutive activation of Wnt signaling favors generation of memory CD8 T cells. J Immunol (2009) 1.54
Protective capacity of memory CD8+ T cells is dictated by antigen exposure history and nature of the infection. Immunity (2011) 1.53
Single-dose immunogenicity and protective efficacy of simian adenoviral vectors against Plasmodium berghei. Eur J Immunol (2008) 1.50
Pathogen-specific inflammatory milieux tune the antigen sensitivity of CD8(+) T cells by enhancing T cell receptor signaling. Immunity (2012) 1.50
A default pathway of memory CD8 T cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation. J Immunol (2009) 1.50
Platelet-derived CD154 enables T-cell priming and protection against Listeria monocytogenes challenge. Blood (2008) 1.40
Duration of infection and antigen display have minimal influence on the kinetics of the CD4+ T cell response to Listeria monocytogenes infection. J Immunol (2004) 1.38
Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virus. Immunity (2013) 1.33
Constitutive expression of IL-7 receptor alpha does not support increased expansion or prevent contraction of antigen-specific CD4 or CD8 T cells following Listeria monocytogenes infection. J Immunol (2008) 1.30
NFIL3/E4BP4 is a key transcription factor for CD8α⁺ dendritic cell development. Blood (2011) 1.25
Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice. Immunity (2003) 1.23
TRAIL deficiency delays, but does not prevent, erosion in the quality of "helpless" memory CD8 T cells. J Immunol (2006) 1.22
Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly. Proc Natl Acad Sci U S A (2010) 1.21
Whole parasite vaccination approaches for prevention of malaria infection. Trends Immunol (2012) 1.18
Population dynamics of naive and memory CD8 T cell responses after antigen stimulations in vivo. J Immunol (2011) 1.18
Differential effector pathways regulate memory CD8 T cell immunity against Plasmodium berghei versus P. yoelii sporozoites. J Immunol (2010) 1.17
Probing CD8 T cell responses with Listeria monocytogenes infection. Adv Immunol (2012) 1.17
Secondary CD8+ T-cell responses are controlled by systemic inflammation. Eur J Immunol (2011) 1.16
IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo. J Exp Med (2013) 1.16
Modulating numbers and phenotype of CD8+ T cells in secondary immune responses. Eur J Immunol (2010) 1.11
CD8(+)-T-cell response to secreted and nonsecreted antigens delivered by recombinant Listeria monocytogenes during secondary infection. Infect Immun (2002) 1.09
The onset of CD8+-T-cell contraction is influenced by the peak of Listeria monocytogenes infection and antigen display. Infect Immun (2006) 1.07
CD8 T cell memory development: CD4 T cell help is appreciated. Immunol Res (2007) 1.06
IL-15 regulates memory CD8+ T cell O-glycan synthesis and affects trafficking. J Clin Invest (2014) 1.05
A role for IFN-gamma from antigen-specific CD8+ T cells in protective immunity to Listeria monocytogenes. J Immunol (2007) 1.05
Naive, effector and memory CD8 T-cell trafficking: parallels and distinctions. Immunotherapy (2011) 1.03
Aberrant contraction of antigen-specific CD4 T cells after infection in the absence of gamma interferon or its receptor. Infect Immun (2006) 1.03
Simultaneous assessment of antigen-stimulated cytokine production and memory subset composition of memory CD8 T cells. J Immunol Methods (2006) 1.02
T cell conditioning explains early disappearance of the memory CD8 T cell response to infection. J Immunol (2006) 1.02
Immunologic considerations for generating memory CD8 T cells through vaccination. Cell Microbiol (2011) 1.02
Listeriolysin O-deficient Listeria monocytogenes as a vaccine delivery vehicle: antigen-specific CD8 T cell priming and protective immunity. J Immunol (2006) 1.02
Division-linked generation of death-intermediates regulates the numerical stability of memory CD8 T cells. Proc Natl Acad Sci U S A (2012) 1.01
CD8 T cell immunity to Plasmodium permits generation of protective antibodies after repeated sporozoite challenge. Vaccine (2009) 1.01
Interleukin-18-related genes are induced during the contraction phase but do not play major roles in regulating the dynamics or function of the T-cell response to Listeria monocytogenes infection. Infect Immun (2009) 1.00
MHC class Ia-restricted memory T cells inhibit expansion of a nonprotective MHC class Ib (H2-M3)-restricted memory response. Nat Immunol (2004) 0.99
In vivo generation of pathogen-specific Th1 cells in the absence of the IFN-gamma receptor. J Immunol (2005) 0.98
Strategies and implications for prime-boost vaccination to generate memory CD8 T cells. Adv Exp Med Biol (2011) 0.95
Plasmodium-host interactions directly influence the threshold of memory CD8 T cells required for protective immunity. J Immunol (2011) 0.95
Toll-like receptor 4 deficiency increases disease and mortality after mouse hepatitis virus type 1 infection of susceptible C3H mice. J Virol (2009) 0.94
Cutting edge: differential self-peptide/MHC requirement for maintaining CD8 T cell function versus homeostatic proliferation. J Immunol (2005) 0.93
Deficient anti-listerial immunity in the absence of perforin can be restored by increasing memory CD8+ T cell numbers. J Immunol (2003) 0.92
Cutting edge: rapid boosting of cross-reactive memory CD8 T cells broadens the protective capacity of the Flumist vaccine. J Immunol (2013) 0.92
T cells undergo rapid ON/OFF but not ON/OFF/ON cycling of cytokine production in response to antigen. J Immunol (2005) 0.91
High initial frequency of TCR-transgenic CD8 T cells alters inflammation and pathogen clearance without affecting memory T cell function. Mol Immunol (2009) 0.90
Quantitation of CD8+ T cell expansion, memory, and protective immunity after immunization with peptide-coated dendritic cells. J Immunol (2002) 0.89
Differential role of "Signal 3" inflammatory cytokines in regulating CD8 T cell expansion and differentiation in vivo. Front Immunol (2011) 0.89
Microsphere priming facilitates induction of potent therapeutic T-cell immune responses against autochthonous liver cancers. Eur J Immunol (2014) 0.88
Inflammatory IL-15 is required for optimal memory T cell responses. J Clin Invest (2015) 0.88
Viral vector vaccines make memory T cells against malaria. Immunology (2007) 0.86
Memory lanes. Nat Immunol (2003) 0.86
Cutting edge: attrition of Plasmodium-specific memory CD8 T cells results in decreased protection that is rescued by booster immunization. J Immunol (2011) 0.85
Tracking the total CD8 T cell response following whole Plasmodium vaccination. Methods Mol Biol (2013) 0.85
CD8(+) T-cell homeostasis after infection: setting the 'curve'. Microbes Infect (2002) 0.85
Protective and pathologic roles of the immune response to mouse hepatitis virus type 1: implications for severe acute respiratory syndrome. J Virol (2009) 0.85
Predicting CD62L expression during the CD8+ T-cell response in vivo. Immunol Cell Biol (2009) 0.84
The impact of pre-existing memory on differentiation of newly recruited naive CD8 T cells. J Immunol (2011) 0.84
Targeting the GA binding protein beta1L isoform does not perturb lymphocyte development and function. Mol Cell Biol (2008) 0.84
Differentiation of central memory CD8 T cells is independent of CD62L-mediated trafficking to lymph nodes. J Immunol (2009) 0.84
Adaptable TCR avidity thresholds for negative selection. J Immunol (2008) 0.83
The role of inflammation in the generation and maintenance of memory T cells. Adv Exp Med Biol (2010) 0.83
Cutting edge: Expression of FcγRIIB tempers memory CD8 T cell function in vivo. J Immunol (2013) 0.81
Correlates of protective immunity following whole sporozoite vaccination against malaria. Immunol Res (2014) 0.81
Initial TCR transgenic precursor frequency alters functional behaviour of CD8 T cells responding to acute infection. Adv Exp Med Biol (2009) 0.81
Epitope specificity of memory CD8+ T cells dictates vaccination-induced mortality in LCMV-infected perforin-deficient mice. Eur J Immunol (2012) 0.81
Antigen experience shapes phenotype and function of memory Th1 cells. PLoS One (2013) 0.80
In vivo CD8+ T cell dynamics in the liver of Plasmodium yoelii immunized and infected mice. PLoS One (2013) 0.80
Perforin plays an unexpected role in regulating T-cell contraction during prolonged Listeria monocytogenes infection. Eur J Immunol (2012) 0.79
T cell epitope specificity and pathogenesis of mouse hepatitis virus-1-induced disease in susceptible and resistant hosts. J Immunol (2010) 0.79
The generation and modulation of antigen-specific memory CD8 T cell responses. J Leukoc Biol (2006) 0.79
Generation and maintenance of Listeria-specific CD8+ T cell responses in perforin-deficient mice chronically infected with LCMV. Virology (2007) 0.79
TCR beta chain that forms peptide-independent alloreactive TCR transfers reduced reactivity with irrelevant peptide/MHC complex. J Immunol (2007) 0.77
Paradoxical Increase in Mortality and Rupture of Intracranial Aneurysms in Microsomal Prostaglandin E2 Synthase Type 1-Deficient Mice: Attenuation by Aspirin. Neurosurgery (2015) 0.77
A "memorable" NK cell discovery. Cell Res (2009) 0.77
Aged mice exhibit a severely diminished CD8 T cell response following respiratory syncytial virus infection. J Virol (2013) 0.76
The Role of Il-12 and Type I Interferon in Governing the Magnitude of CD8 T Cell Responses. Adv Exp Med Biol (2015) 0.75
One bug or another: promiscuous T cells form lifelong memory. Immunity (2013) 0.75
Correction: Discriminating Protective from Nonprotective Plasmodium-Specific CD8+ T Cell Responses. J Immunol (2016) 0.75