Published in Cancer on August 15, 2006
Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J (2007) 6.26
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer. Nat Rev Cancer (2008) 6.10
Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis. Oncogene (2008) 2.48
SCF E3 ubiquitin ligases as anticancer targets. Curr Cancer Drug Targets (2011) 1.46
Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease. Blood (2008) 1.17
Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death. Int J Cancer (2008) 1.15
Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis. Am J Pathol (2008) 1.03
Macrophage migration inhibitory factor regulates proliferation of gastric cancer cells via the PI3K/Akt pathway. World J Gastroenterol (2009) 1.02
Skp2 is a promising therapeutic target in breast cancer. Front Oncol (2012) 0.95
Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours. BMC Cancer (2008) 0.94
Epigenetic modifications induced by RGC-32 in colon cancer. Exp Mol Pathol (2009) 0.94
p27Kip1 in stage III colon cancer: implications for outcome following adjuvant chemotherapy in cancer and leukemia group B protocol 89803. Clin Cancer Res (2009) 0.90
SKP2 high expression, KIT exon 11 deletions, and gastrointestinal bleeding as predictors of poor prognosis in primary gastrointestinal stromal tumors. PLoS One (2013) 0.88
Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis. Mol Carcinog (2015) 0.85
2-methoxyestradiol-induced cell death in osteosarcoma cells is preceded by cell cycle arrest. J Cell Biochem (2008) 0.85
Strategies for the identification of novel inhibitors of deubiquitinating enzymes. Biochem Soc Trans (2008) 0.85
Ablation of galectin-3 induces p27(KIP1)-dependent premature senescence without oncogenic stress. Cell Death Differ (2014) 0.84
Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2. J Cell Mol Med (2007) 0.84
Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib. Int J Colorectal Dis (2010) 0.82
14-3-3ζ orchestrates mammary tumor onset and progression via miR-221-mediated cell proliferation. Cancer Res (2013) 0.80
Skp2 is over-expressed in breast cancer and promotes breast cancer cell proliferation. Cell Cycle (2016) 0.78
Increased expression of Cks1 protein is associated with lymph node metastasis and poor prognosis in nasopharyngeal carcinoma. Diagn Pathol (2017) 0.75
The expression of the ubiquitin ligase subunit Cks1 in human breast cancer. Breast Cancer Res (2005) 1.30
Differential effects of doxorubicin treatment on cell cycle arrest and Skp2 expression in breast cancer cells. Anticancer Drugs (2007) 0.95
Regulation of APC/C (Cdh1) ubiquitin ligase in differentiation of human embryonic stem cells. Cell Cycle (2010) 0.87
Over-expression of Skp2 is associated with resistance to preoperative doxorubicin-based chemotherapy in primary breast cancer. Breast Cancer Res (2008) 0.86
Agonist-specific down regulation of mu-opioid receptors: Different cellular pathways are activated by different opioid agonists. Life Sci (2008) 0.79
Thrombin is a selective inducer of heparanase release from platelets and granulocytes via protease-activated receptor-1. Thromb Haemost (2017) 0.75