Published in Mol Immunol on July 07, 2006
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The Kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-Myc. J Virol (2007) 1.36
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Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion. Proc Natl Acad Sci U S A (2007) 1.82
A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates. J Exp Med (2007) 1.70
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Origin, fate, and function of epicardium-derived cells (EPDCs) in normal and abnormal cardiac development. ScientificWorldJournal (2007) 1.57
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Endogenous HLA class II epitopes that are immunogenic in vivo show distinct behavior toward HLA-DM and its natural inhibitor HLA-DO. Blood (2012) 1.49
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The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER. J Cell Biol (2009) 1.48
Two mechanistically distinct immune evasion proteins of cowpox virus combine to avoid antiviral CD8 T cells. Cell Host Microbe (2009) 1.48
Epstein-Barr virus gp42 is posttranslationally modified to produce soluble gp42 that mediates HLA class II immune evasion. J Virol (2005) 1.36
Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing. Proc Natl Acad Sci U S A (2005) 1.36
The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradation. PLoS Pathog (2009) 1.31
The DNase of gammaherpesviruses impairs recognition by virus-specific CD8+ T cells through an additional host shutoff function. J Virol (2007) 1.29
Viral evasion of T cell immunity: ancient mechanisms offering new applications. Curr Opin Immunol (2010) 1.24
Impaired transporter associated with antigen processing-dependent peptide transport during productive EBV infection. J Immunol (2005) 1.23
Interference with T cell receptor-HLA-DR interactions by Epstein-Barr virus gp42 results in reduced T helper cell recognition. Proc Natl Acad Sci U S A (2003) 1.20
Epstein-Barr virus evasion of CD8(+) and CD4(+) T cell immunity via concerted actions of multiple gene products. Semin Cancer Biol (2008) 1.20
The adenovirus capsid: major progress in minor proteins. J Gen Virol (2005) 1.19
Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation. J Immunol (2009) 1.17
Conversion of mature human β-cells into glucagon-producing α-cells. Diabetes (2013) 1.16
Internalization of oncolytic reovirus by human dendritic cell carriers protects the virus from neutralization. Clin Cancer Res (2011) 1.12
Stage-specific inhibition of MHC class I presentation by the Epstein-Barr virus BNLF2a protein during virus lytic cycle. PLoS Pathog (2009) 1.11
DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1. Oncogene (2005) 1.10
The coiled-coil domain of the adenovirus type 5 protein IX is dispensable for capsid incorporation and thermostability. J Virol (2005) 1.10
Immune responses against adenoviral vectors and their transgene products: a review of strategies for evasion. Crit Rev Oncol Hematol (2004) 1.09
Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IX. J Virol (2004) 1.08
Herpesviruses and immunity: the art of evasion. Vet Microbiol (2010) 1.08
Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP. PLoS Pathog (2008) 1.08
Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates. J Cell Biol (2009) 1.07
Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells. J Cell Sci (2006) 1.02
The comparative genomics of human respiratory syncytial virus subgroups A and B: genetic variability and molecular evolutionary dynamics. J Virol (2013) 1.01
Neuroregenerative effects of lentiviral vector-mediated GDNF expression in reimplanted ventral roots. Mol Cell Neurosci (2008) 1.00
Human cytomegalovirus-encoded US2 differentially affects surface expression of MHC class I locus products and targets membrane-bound, but not soluble HLA-G1 for degradation. J Immunol (2003) 0.99
Increased glia-specific transgene expression with glial fibrillary acidic protein promoters containing multiple enhancer elements. J Neurosci Res (2006) 0.98
Increased vulnerability of pre-existing atherosclerosis in ApoE-deficient mice following adenovirus-mediated Fas ligand gene transfer. Atherosclerosis (2005) 0.97
Mitogen-activated protein kinase (MAPK) phosphatase-1 and -4 attenuate p38 MAPK during dexamethasone-induced insulin resistance in 3T3-L1 adipocytes. Mol Endocrinol (2004) 0.96
Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther (2010) 0.95
Bovine herpesvirus 1 UL49.5 protein inhibits the transporter associated with antigen processing despite complex formation with glycoprotein M. J Virol (2006) 0.94
Development of an inducible suicide gene system based on human caspase 8. Cancer Gene Ther (2005) 0.92
Emergence of viral diseases: mathematical modeling as a tool for infection control, policy and decision making. Crit Rev Microbiol (2010) 0.92
KRAS(D13) Promotes apoptosis of human colorectal tumor cells by ReovirusT3D and oxaliplatin but not by tumor necrosis factor-related apoptosis-inducing ligand. Cancer Res (2006) 0.92
The varicellovirus-encoded TAP inhibitor UL49.5 regulates the presentation of CTL epitopes by Qa-1b1. J Immunol (2007) 0.92
EBV protein BNLF2a exploits host tail-anchored protein integration machinery to inhibit TAP. J Immunol (2011) 0.91
Ganciclovir nucleotides accumulate in mitochondria of rat liver cells expressing the herpes simplex virus thymidine kinase gene. J Gene Med (2003) 0.90
Gene therapy with apoptin induces regression of xenografted human hepatomas. Cancer Gene Ther (2002) 0.90
Subtle sequence variation among MHC class I locus products greatly influences sensitivity to HCMV US2- and US11-mediated degradation. Int Immunol (2005) 0.90
Inhibition of mouse TAP by immune evasion molecules encoded by non-murine herpesviruses. Mol Immunol (2011) 0.89
ATF3 and Fra1 have opposite functions in JNK- and ERK-dependent DNA damage responses. DNA Repair (Amst) (2008) 0.89
Signaling of a varicelloviral factor across the endoplasmic reticulum membrane induces destruction of the peptide-loading complex and immune evasion. J Biol Chem (2008) 0.89
Exploitation of herpesvirus immune evasion strategies to modify the immunogenicity of human mesenchymal stem cell transplants. PLoS One (2011) 0.88
Isolated human islets contain a distinct population of mesenchymal stem cells. Islets (2010) 0.88
The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex. J Immunol (2008) 0.88
Sensitization to apoptosis underlies KrasD12-dependent oncolysis of murine C26 colorectal carcinoma cells by reovirus T3D. J Virol (2005) 0.88
Human cytomegalovirus-encoded US2 and US11 target unassembled MHC class I heavy chains for degradation. Mol Immunol (2005) 0.88
A system for efficient generation of adenovirus protein IX-producing helper cell lines. J Gene Med (2006) 0.88
Lentiviral vector-mediated reporter gene expression in avulsed spinal ventral root is short-term, but is prolonged using an immune "stealth" transgene. Restor Neurol Neurosci (2007) 0.88
Amino acid composition of alpha1/alpha2 domains and cytoplasmic tail of MHC class I molecules determine their susceptibility to human cytomegalovirus US11-mediated down-regulation. Eur J Immunol (2003) 0.88
Activin A impairs insulin action in cardiomyocytes via up-regulation of miR-143. Cardiovasc Res (2013) 0.87
Non-human viruses developed as therapeutic agent for use in humans. Rev Med Virol (2011) 0.86
The "Bridge" in the Epstein-Barr virus alkaline exonuclease protein BGLF5 contributes to shutoff activity during productive infection. J Virol (2012) 0.86
CD8+ T cell responses against TAP-inhibited cells are readily detected in the human population. J Immunol (2010) 0.86
The 45-kDa form of Pdx-1 does not result from post-translational modifications. Biochem Biophys Res Commun (2008) 0.85
Modification of mammalian reoviruses for use as oncolytic agents. Expert Opin Biol Ther (2009) 0.85
β-Cell Generation: Can Rodent Studies Be Translated to Humans? J Transplant (2011) 0.85
The capacity of UL49.5 proteins to inhibit TAP is widely distributed among members of the genus Varicellovirus. J Virol (2010) 0.85
Exploiting human herpesvirus immune evasion for therapeutic gain: potential and pitfalls. Immunol Cell Biol (2011) 0.84
Reappraisal of biosafety risks posed by PERVs in xenotransplantation. Rev Med Virol (2008) 0.84
Construction and biological activity of a full-length molecular clone of human Torque teno virus (TTV) genotype 6. FEBS J (2007) 0.83
Cross-species transfer of viruses: implications for the use of viral vectors in biomedical research, gene therapy and as live-virus vaccines. J Gene Med (2005) 0.83
Gene therapy and cement injection for restabilization of loosened hip prostheses. Hum Gene Ther (2008) 0.83
New role of signal peptide peptidase to liberate C-terminal peptides for MHC class I presentation. J Immunol (2013) 0.82
Directed adenovirus evolution using engineered mutator viral polymerases. Nucleic Acids Res (2010) 0.82
The p38 mitogen-activated protein kinase inhibitor SB203580 reduces glucose turnover by the glucose transporter-4 of 3T3-L1 adipocytes in the insulin-stimulated state. Endocrinology (2005) 0.82
Noncytotoxic inhibition of cytomegalovirus replication through NK cell protease granzyme M-mediated cleavage of viral phosphoprotein 71. J Immunol (2010) 0.82
Structural and functional analysis of the TAP-inhibiting UL49.5 proteins of varicelloviruses. Mol Immunol (2011) 0.81
Recombinant adenovirus-transduced human dendritic cells engineered to secrete interleukin-10 (IL-10) suppress Th1-type responses while selectively activating IL-10-producing CD4+ T cells. Hum Immunol (2004) 0.81
TAP-inhibiting proteins US6, ICP47 and UL49.5 differentially affect minor and major histocompatibility antigen-specific recognition by cytotoxic T lymphocytes. Int Immunol (2007) 0.81
Genetically engineered human islets protected from CD8-mediated autoimmune destruction in vivo. Mol Ther (2013) 0.81
Isolation of reovirus T3D mutants capable of infecting human tumor cells independent of junction adhesion molecule-A. PLoS One (2012) 0.81
The nested open reading frame in the Epstein-Barr virus nuclear antigen-1 mRNA encodes a protein capable of inhibiting antigen presentation in cis. Mol Immunol (2007) 0.81
Serpina1 (alpha1-AT) is synthesized in the osteoblastic stem cell niche. Exp Hematol (2009) 0.80
Synthesis and biological evaluation of a chitobiose-based peptide N-glycanase inhibitor library. J Org Chem (2009) 0.80
A potentially immunologically inert derivative of the reverse tetracycline-controlled transactivator. Biotechnol Lett (2010) 0.80
Biosafety of non-human therapeutic viruses in clinical gene therapy. Curr Gene Ther (2013) 0.80
Efficient mobilization of E1-deleted adenovirus type 5 vectors by wild-type adenoviruses of other serotypes. J Gen Virol (2002) 0.80
Molecular imaging and treatment of malignant gliomas following adenoviral transfer of the herpes simplex virus-thymidine kinase gene and the somatostatin receptor subtype 2 gene. Cancer Biother Radiopharm (2004) 0.80
Optimization of short-term transgene expression by sodium butyrate and ubiquitous chromatin opening elements (UCOEs). J Gene Med (2007) 0.79
Adenoviral vectors stimulate glucagon transcription in human mesenchymal stem cells expressing pancreatic transcription factors. PLoS One (2012) 0.79
Towards gene therapy in prosthesis loosening: efficient killing of interface cells by gene-directed enzyme prodrug therapy with nitroreductase and the prodrug CB1954. J Gene Med (2005) 0.79
A lentiviral vector-based adenovirus fiber-pseudotyping approach for expedited functional assessment of candidate retargeted fibers. J Gene Med (2009) 0.78
Rat cytomegalovirus induces a temporal downregulation of major histocompatibility complex class I cell surface expression. Viral Immunol (2005) 0.78
Truncating the i-leader open reading frame enhances release of human adenovirus type 5 in glioma cells. Virol J (2011) 0.78