PubRank

Greg J Towers

Author PubWeight™ 86.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities. Proc Natl Acad Sci U S A 2004 5.08
2 Restriction of multiple divergent retroviruses by Lv1 and Ref1. EMBO J 2003 4.19
3 Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion. PLoS Pathog 2009 2.92
4 Disease-associated XMRV sequences are consistent with laboratory contamination. Retrovirology 2010 2.90
5 HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency. PLoS Pathog 2011 2.68
6 Differential restriction of human immunodeficiency virus type 2 and simian immunodeficiency virus SIVmac by TRIM5alpha alleles. J Virol 2005 2.43
7 Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21). Proc Natl Acad Sci U S A 2010 2.36
8 Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration. Proc Natl Acad Sci U S A 2009 2.21
9 Independent evolution of an antiviral TRIMCyp in rhesus macaques. Proc Natl Acad Sci U S A 2008 2.15
10 HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2. PLoS Pathog 2011 2.00
11 Characterization of murine leukemia virus restriction in mammals. J Virol 2003 1.97
12 The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin. PLoS Pathog 2010 1.94
13 As(2)O(3) enhances retroviral reverse transcription and counteracts Ref1 antiviral activity. J Virol 2003 1.94
14 Cyclophilin A renders human immunodeficiency virus type 1 sensitive to Old World monkey but not human TRIM5 alpha antiviral activity. J Virol 2006 1.69
15 CPSF6 defines a conserved capsid interface that modulates HIV-1 replication. PLoS Pathog 2012 1.64
16 Influence of gag on human immunodeficiency virus type 1 species-specific tropism. J Virol 2004 1.57
17 An active TRIM5 protein in rabbits indicates a common antiviral ancestor for mammalian TRIM5 proteins. J Virol 2007 1.54
18 Active site remodeling switches HIV specificity of antiretroviral TRIMCyp. Nat Struct Mol Biol 2009 1.53
19 HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature 2016 1.39
20 Gag determinants of fitness and drug susceptibility in protease inhibitor-resistant human immunodeficiency virus type 1. J Virol 2009 1.37
21 SAMHD1-dependent retroviral control and escape in mice. EMBO J 2013 1.36
22 Isolation of an active Lv1 gene from cattle indicates that tripartite motif protein-mediated innate immunity to retroviral infection is widespread among mammals. J Virol 2006 1.35
23 HIV-1 infection of macrophages is dependent on evasion of innate immune cellular activation. AIDS 2009 1.34
24 Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha. Trends Microbiol 2008 1.33
25 Full-length HIV-1 Gag determines protease inhibitor susceptibility within in vitro assays. AIDS 2010 1.29
26 Rhesus macaque TRIM5 alleles have divergent antiretroviral specificities. J Virol 2008 1.29
27 Cyclophilin A levels dictate infection efficiency of human immunodeficiency virus type 1 capsid escape mutants A92E and G94D. J Virol 2008 1.27
28 Retroviral restriction factors Fv1 and TRIM5alpha act independently and can compete for incoming virus before reverse transcription. J Virol 2006 1.25
29 Phylogenetic analysis of murine leukemia virus sequences from longitudinally sampled chronic fatigue syndrome patients suggests PCR contamination rather than viral evolution. J Virol 2011 1.23
30 Analysis of XMRV integration sites from human prostate cancer tissues suggests PCR contamination rather than genuine human infection. Retrovirology 2011 1.20
31 No evidence of XMRV in prostate cancer cohorts in the Midwestern United States. Retrovirology 2011 1.18
32 HIV-1 Group P is unable to antagonize human tetherin by Vpu, Env or Nef. Retrovirology 2011 1.18
33 Cyclosporine increases human immunodeficiency virus type 1 vector transduction of primary mouse cells. J Virol 2006 1.09
34 Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity. PLoS Pathog 2010 1.09
35 TRIM22 inhibits influenza A virus infection by targeting the viral nucleoprotein for degradation. J Virol 2013 1.08
36 Truncation of TRIM5 in the Feliformia explains the absence of retroviral restriction in cells of the domestic cat. J Virol 2009 1.08
37 Feline tetherin efficiently restricts release of feline immunodeficiency virus but not spreading of infection. J Virol 2011 1.04
38 No evidence of XMRV or related retroviruses in a London HIV-1-positive patient cohort. PLoS One 2011 1.04
39 HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358. Retrovirology 2013 1.01
40 Fusion of cyclophilin A to Fv1 enables cyclosporine-sensitive restriction of human and feline immunodeficiency viruses. J Virol 2007 0.97
41 Impact of the N348I mutation in HIV-1 reverse transcriptase on nonnucleoside reverse transcriptase inhibitor resistance in non-subtype B HIV-1. Antimicrob Agents Chemother 2011 0.96
42 Tetherin restricts herpes simplex virus 1 and is antagonized by glycoprotein M. J Virol 2013 0.95
43 Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells. J Virol 2012 0.93
44 Adherent human alveolar macrophages exhibit a transient pro-inflammatory profile that confounds responses to innate immune stimulation. PLoS One 2012 0.93
45 Analysis of the human immunodeficiency virus type 1 M group Vpu domains involved in antagonizing tetherin. J Gen Virol 2011 0.92
46 A tail of Tetherin: how pandemic HIV-1 conquered the world. Cell Host Microbe 2009 0.91
47 Hare TRIM5α restricts divergent retroviruses and exhibits significant sequence variation from closely related lagomorpha TRIM5 genes. J Virol 2010 0.87
48 Identification of an arsenic-sensitive block to primate lentiviral infection of human dendritic cells. J Virol 2007 0.87
49 HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01. J Virol 2013 0.85
50 Cellular restriction of retrovirus particle-mediated mRNA transfer. J Virol 2008 0.85
51 Inhibition of retroviral replication by members of the TRIM protein family. Curr Top Microbiol Immunol 2013 0.84
52 Diversity of TRIM5α and TRIMCyp sequences in cynomolgus macaques from different geographical origins. Immunogenetics 2011 0.83
53 Endoplasmic reticulum degradation-enhancing α-mannosidase-like protein 1 targets misfolded HLA-B27 dimers for endoplasmic reticulum-associated degradation. Arthritis Rheumatol 2014 0.81
54 Diverse HIV viruses are targeted by a conformationally dynamic antiviral. Nat Struct Mol Biol 2012 0.81
55 Upregulation of TRIM5α gene expression after live-attenuated simian immunodeficiency virus vaccination in Mauritian cynomolgus macaques, but TRIM5α genotype has no impact on virus acquisition or vaccination outcome. J Gen Virol 2012 0.81
56 Vpx complementation of 'non-macrophage tropic' R5 viruses reveals robust entry of infectious HIV-1 cores into macrophages. Retrovirology 2014 0.81
57 Porcine endogenous retroviruses PERV A and A/C recombinant are insensitive to a range of divergent mammalian TRIM5alpha proteins including human TRIM5alpha. J Gen Virol 2009 0.81
58 Lentiviral gene therapy against human immunodeficiency virus type 1, using a novel human TRIM21-cyclophilin A restriction factor. Hum Gene Ther 2012 0.79
59 Ultra structural characterisation of tetherin - a protein capable of preventing viral release from the plasma membrane. Viruses 2010 0.75