Published in Biochem Pharmacol on July 17, 2006
Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol (2009) 9.41
A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell (2012) 4.89
Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells. J Immunol (2008) 3.91
Nutritional immunity beyond iron: a role for manganese and zinc. Curr Opin Chem Biol (2009) 2.69
Nutrient metal sequestration by calprotectin inhibits bacterial superoxide defense, enhancing neutrophil killing of Staphylococcus aureus. Cell Host Microbe (2011) 2.66
RAGE signaling sustains inflammation and promotes tumor development. J Exp Med (2008) 2.51
microRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis. Cancer Res (2009) 2.51
Functions of S100 proteins. Curr Mol Med (2013) 2.43
Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury. J Transl Med (2012) 2.37
RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis. Carcinogenesis (2008) 2.33
Alarmins: awaiting a clinical response. J Clin Invest (2012) 2.19
IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. J Immunol (2010) 2.12
S100A8/A9 activate key genes and pathways in colon tumor progression. Mol Cancer Res (2011) 1.98
Genetic architecture of mouse skin inflammation and tumour susceptibility. Nature (2009) 1.89
Commensal-dendritic-cell interaction specifies a unique protective skin immune signature. Nature (2015) 1.72
Endogenous damage-associated molecular pattern molecules at the crossroads of inflammation and cancer. Neoplasia (2009) 1.66
Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens. Proc Natl Acad Sci U S A (2013) 1.64
A molecular mechanism for bacterial susceptibility to zinc. PLoS Pathog (2011) 1.61
Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice. J Clin Invest (2011) 1.56
Epithelial cell-derived S100 calcium-binding proteins as key mediators in the hallmark acute neutrophil response during Candida vaginitis. Infect Immun (2010) 1.38
Aldara activates TLR7-independent immune defence. Nat Commun (2013) 1.34
TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms. Cancer Discov (2011) 1.26
Receptor for advanced glycation end products and its involvement in inflammatory diseases. Int J Inflam (2013) 1.22
S100A8 and S100A9: new insights into their roles in malignancy. J Innate Immun (2011) 1.20
The receptor RAGE: Bridging inflammation and cancer. Cell Commun Signal (2009) 1.20
Review of S100A9 biology and its role in cancer. Biochim Biophys Acta (2012) 1.19
MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese. Infect Immun (2013) 1.17
Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis. J Cell Biol (2010) 1.14
Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression. Cancer Res (2011) 1.14
Metal limitation and toxicity at the interface between host and pathogen. FEMS Microbiol Rev (2014) 1.14
Cytokines in the host response to Candida vaginitis: Identifying a role for non-classical immune mediators, S100 alarmins. Cytokine (2011) 1.11
Lack of an endogenous anti-inflammatory protein in mice enhances colonization of B16F10 melanoma cells in the lungs. J Biol Chem (2010) 1.11
Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes. Int J Mol Sci (2012) 1.09
Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate. PLoS One (2009) 1.07
Icariin and its derivative, ICT, exert anti-inflammatory, anti-tumor effects, and modulate myeloid derived suppressive cells (MDSCs) functions. Int Immunopharmacol (2011) 1.05
Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis. PLoS Genet (2010) 1.04
The phenotypic fate and functional role for bone marrow-derived stem cells in liver fibrosis. J Hepatol (2011) 1.04
Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization. Int J Cancer (2011) 1.04
TNFalpha shedding and epidermal inflammation are controlled by Jun proteins. Genes Dev (2009) 1.04
Protein profiling of human breast tumor cells identifies novel biomarkers associated with molecular subtypes. Mol Cell Proteomics (2008) 1.04
Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice. J Clin Invest (2009) 1.03
S100A8 and S100A9 promotes invasion and migration through p38 mitogen-activated protein kinase-dependent NF-κB activation in gastric cancer cells. Mol Cells (2013) 1.03
Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. J Mol Med (Berl) (2011) 1.02
Zinc replenishment reverses overexpression of the proinflammatory mediator S100A8 and esophageal preneoplasia in the rat. Gastroenterology (2008) 1.02
Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons. Am J Physiol Lung Cell Mol Physiol (2013) 1.01
IL-17 mediated inflammation promotes tumor growth and progression in the skin. PLoS One (2012) 1.01
Dietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature. Oncogene (2011) 1.00
Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model. J Immunol (2013) 1.00
Effects of iron loading on muscle: genome-wide mRNA expression profiling in the mouse. BMC Genomics (2007) 1.00
miR-24 functions as a tumor suppressor in Hep2 laryngeal carcinoma cells partly through down-regulation of the S100A8 protein. Oncol Rep (2011) 0.99
Relating form and function of EF-hand calcium binding proteins. Acc Chem Res (2011) 0.99
Cell signals influencing hepatic fibrosis. Int J Hepatol (2012) 0.98
S100a9 knockdown decreases the memory impairment and the neuropathology in Tg2576 mice, AD animal model. PLoS One (2010) 0.98
Novel insights into the role of S100A8/A9 in skin biology. Exp Dermatol (2012) 0.98
RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia. BMC Genomics (2012) 0.97
The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration. PLoS Pathog (2014) 0.96
New Concepts for Translational Head and Neck Oncology: Lessons from HPV-Related Oropharyngeal Squamous Cell Carcinomas. Front Oncol (2012) 0.95
Nutritional Immunity: S100 Proteins at the Host-Pathogen Interface. J Biol Chem (2015) 0.95
Induction of metastatic gastric cancer by peroxisome proliferator-activated receptorδ activation. PPAR Res (2010) 0.95
Calcium-binding S100 protein expression in pterygium. Mol Vis (2009) 0.95
Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats. BMC Cancer (2010) 0.94
The role of calprotectin in pediatric disease. Biomed Res Int (2013) 0.93
Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression. Int J Cancer (2010) 0.93
A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse. J Hepatol (2013) 0.92
TroA of Streptococcus suis is required for manganese acquisition and full virulence. J Bacteriol (2011) 0.92
S100A expression in normal corneal-limbal epithelial cells and ocular surface squamous cell carcinoma tissue. Mol Vis (2011) 0.91
Inhibition of the autocrine IL-6-JAK2-STAT3-calprotectin axis as targeted therapy for HR-/HER2+ breast cancers. Genes Dev (2015) 0.91
Identification of poly(ADP-ribose)polymerase-1 and Ku70/Ku80 as transcriptional regulators of S100A9 gene expression. BMC Mol Biol (2006) 0.91
Mechanisms of action of tasquinimod on the tumour microenvironment. Cancer Chemother Pharmacol (2013) 0.91
Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice. Respir Res (2010) 0.90
MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency. Oncotarget (2016) 0.90
Robust shifts in S100a9 expression with aging: a novel mechanism for chronic inflammation. Sci Rep (2013) 0.89
Instruction of myeloid cells by the tumor microenvironment: Open questions on the dynamics and plasticity of different tumor-associated myeloid cell populations. Oncoimmunology (2012) 0.89
Macrophage-derived biomarkers of idiopathic pulmonary fibrosis. Pulm Med (2010) 0.89
Acinetobacter baumannii response to host-mediated zinc limitation requires the transcriptional regulator Zur. J Bacteriol (2014) 0.89
S100A8/A9 (calprotectin) negatively regulates G2/M cell cycle progression and growth of squamous cell carcinoma. PLoS One (2013) 0.89
PPARδ induces estrogen receptor-positive mammary neoplasia through an inflammatory and metabolic phenotype linked to mTOR activation. Cancer Res (2013) 0.89
Carcinoembryonic antigen (CEA) and its receptor hnRNP M are mediators of metastasis and the inflammatory response in the liver. Clin Exp Metastasis (2011) 0.88
The thyroid hormone receptors as modulators of skin proliferation and inflammation. J Biol Chem (2011) 0.88
Proteomic analysis reveals the deregulation of inflammation-related proteins in acupuncture-treated rats with asthma onset. Evid Based Complement Alternat Med (2012) 0.88
Presence of S100A9-positive inflammatory cells in cancer tissues correlates with an early stage cancer and a better prognosis in patients with gastric cancer. BMC Cancer (2012) 0.88
Association between preoperative plasma sRAGE levels and recovery from cardiac surgery. Mediators Inflamm (2013) 0.87
S100 proteins as diagnostic and prognostic markers in colorectal and hepatocellular carcinoma. Hepat Mon (2012) 0.87
12-O-tetradecanoylphorbol-13-acetate promotes breast cancer cell motility by increasing S100A14 level in a Kruppel-like transcription factor 4 (KLF4)-dependent manner. J Biol Chem (2014) 0.86
RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis. J Clin Invest (2016) 0.85
STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis. Cancer Res (2015) 0.85
Prolactin-induced protein mediates cell invasion and regulates integrin signaling in estrogen receptor-negative breast cancer. Breast Cancer Res (2012) 0.85
Clinical relevance of breast cancer-related genes as potential biomarkers for oral squamous cell carcinoma. BMC Cancer (2014) 0.85
Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases. Oncotarget (2015) 0.84
Calprotectin: a novel biomarker for the diagnosis of pleural effusion. Br J Cancer (2012) 0.84
Identification of biomarkers for hepatocellular carcinoma using network-based bioinformatics methods. Eur J Med Res (2013) 0.84
ADAMTS-12 metalloprotease is necessary for normal inflammatory response. J Biol Chem (2012) 0.83
Primary hyperparathyroidism influences the expression of inflammatory and metabolic genes in adipose tissue. PLoS One (2011) 0.83
A prospective proteomic-based study for identifying potential biomarkers for the diagnosis of cholangiocarcinoma. J Gastrointest Surg (2013) 0.83
Potential prognostic biomarkers of pancreatic cancer. Pancreas (2014) 0.83
MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding. Clin Exp Metastasis (2016) 0.82
Urinary calprotectin: a new diagnostic marker in urothelial carcinoma of the bladder. World J Urol (2013) 0.82
Proteomic and pathway analyses reveal a network of inflammatory genes associated with differences in skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice. Carcinogenesis (2012) 0.82
Gene expression changes in the colon epithelium are similar to those of intact colon during late inflammation in interleukin-10 gene deficient mice. PLoS One (2013) 0.82
AP-1 subunits: quarrel and harmony among siblings. J Cell Sci (2004) 5.08
Altered endochondral bone development in matrix metalloproteinase 13-deficient mice. Development (2004) 3.45
Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins. Nature (2005) 3.09
RAGE signaling sustains inflammation and promotes tumor development. J Exp Med (2008) 2.51
Calcium-binding proteins S100A8 and S100A9 as novel diagnostic markers in human prostate cancer. Clin Cancer Res (2005) 1.81
Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects. J Cell Biol (2004) 1.77
Stromal expression of MMP-13 is required for melanoma invasion and metastasis. J Invest Dermatol (2009) 1.75
Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival. Clin Cancer Res (2009) 1.61
Preeclampsia: increased expression of soluble ADAM 12. J Mol Med (Berl) (2005) 1.59
Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer. Int J Cancer (2003) 1.34
Kallikrein 6 induces E-cadherin shedding and promotes cell proliferation, migration, and invasion. Cancer Res (2007) 1.31
Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB. EMBO J (2002) 1.31
S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis. Hepatology (2009) 1.28
p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis. Cancer Res (2006) 1.27
Two-hybrid fluorescence cross-correlation spectroscopy detects protein-protein interactions in vivo. Chemphyschem (2005) 1.27
Gene network dynamics controlling keratinocyte migration. Mol Syst Biol (2008) 1.26
Control of hair follicle cell fate by underlying mesenchyme through a CSL-Wnt5a-FoxN1 regulatory axis. Genes Dev (2010) 1.25
MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma. Carcinogenesis (2009) 1.20
Cell cycle promoting activity of JunB through cyclin A activation. J Biol Chem (2002) 1.20
The receptor RAGE: Bridging inflammation and cancer. Cell Commun Signal (2009) 1.20
Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis. Oncogene (2002) 1.19
Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes. Mol Cell (2012) 1.19
Epidermal development and wound healing in matrix metalloproteinase 13-deficient mice. J Invest Dermatol (2006) 1.18
Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion. Endocrinology (2007) 1.18
Hyaluronan-oligosaccharide-induced transcription of metalloproteases. J Cell Sci (2003) 1.17
Functional characterization of promoter variants of the adiponectin gene complemented by epidemiological data. Diabetes (2008) 1.15
The transcription factor Fos: a Janus-type regulator in health and disease. Histol Histopathol (2009) 1.14
Critical role for NF-kappaB-induced JunB in VEGF regulation and tumor angiogenesis. EMBO J (2007) 1.13
Up-regulation of insulin-like growth factor axis components in human primary prostate cancer correlates with tumor grade. Hum Pathol (2005) 1.09
Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells. Hepatology (2009) 1.09
Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue. Aging Cell (2010) 1.09
Increased keratinocyte proliferation by JUN-dependent expression of PTN and SDF-1 in fibroblasts. J Cell Sci (2005) 1.06
Reversible lymphomagenesis in conditionally c-MYC expressing mice. Int J Cancer (2004) 1.06
Cre recombinase-mediated gene targeting of mesenchymal cells. Genesis (2004) 1.05
Identification of oropharyngeal squamous cell carcinomas with active HPV16 involvement by immunohistochemical analysis of the retinoblastoma protein pathway. Int J Cancer (2013) 1.02
HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas. J Clin Invest (2013) 1.01
Podoplanin is a novel fos target gene in skin carcinogenesis. Cancer Res (2008) 1.00
Receptor for advanced glycation endproducts (RAGE) is a key regulator of oval cell activation and inflammation-associated liver carcinogenesis in mice. Hepatology (2013) 0.99
Identification of novel AP-1 target genes in fibroblasts regulated during cutaneous wound healing. Oncogene (2004) 0.98
Profile of gene expression induced by the tumour promotor TPA in murine epithelial cells. Int J Cancer (2003) 0.97
New Concepts for Translational Head and Neck Oncology: Lessons from HPV-Related Oropharyngeal Squamous Cell Carcinomas. Front Oncol (2012) 0.95
Cutting edge: the AP-1 subunit JunB determines NK cell-mediated target cell killing by regulation of the NKG2D-ligand RAE-1epsilon. J Immunol (2006) 0.95
c-Fos-dependent induction of the small ras-related GTPase Rab11a in skin carcinogenesis. Am J Pathol (2005) 0.93
TAF7 (TAFII55) plays a role in the transcription activation by c-Jun. J Biol Chem (2003) 0.92
JunB is required for endothelial cell morphogenesis by regulating core-binding factor beta. J Cell Biol (2006) 0.92
Junb regulates arterial contraction capacity, cellular contractility, and motility via its target Myl9 in mice. J Clin Invest (2010) 0.92
c-Fos as a regulator of degranulation and cytokine production in FcepsilonRI-activated mast cells. J Immunol (2004) 0.92
Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos. Genes Dev (2013) 0.91
Delayed wound healing and epidermal hyperproliferation in mice lacking JunB in the skin. J Invest Dermatol (2006) 0.90
Defective endochondral ossification in mice with strongly compromised expression of JunB. J Cell Sci (2003) 0.90
An unexpected role for FosB in activation-induced cell death of T cells. Oncogene (2003) 0.89
Loss of matrix metalloproteinase-13 attenuates murine radiation-induced pulmonary fibrosis. Int J Radiat Oncol Biol Phys (2010) 0.88
High invasive melanoma cells induce matrix metalloproteinase-1 synthesis in fibroblasts by interleukin-1alpha and basic fibroblast growth factor-mediated mechanisms. J Invest Dermatol (2005) 0.88
Expression and function of the kallikrein-related peptidase 6 in the human melanoma microenvironment. J Invest Dermatol (2011) 0.87
CD22 regulates early B cell development in BOB.1/OBF.1-deficient mice. Eur J Immunol (2002) 0.87
c-Jun and JunB are essential for hypoglycemia-mediated VEGF induction. Ann N Y Acad Sci (2006) 0.86
Identification and clinical relevance of PD-L1 expression in primary mucosal malignant melanoma of the head and neck. Melanoma Res (2015) 0.86
KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas. Brain (2012) 0.85
Target-selective activation of a TNF prodrug by urokinase-type plasminogen activator (uPA) mediated proteolytic processing at the cell surface. Cancer Immunol Immunother (2006) 0.84
Differential enhancement of a cutaneous HPV promoter by DeltaNP63alpha, Jun and mutant p53. Cell Cycle (2005) 0.84
Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation. Neuro Oncol (2012) 0.84
CEBPbeta, JunD and c-Jun contribute to the transcriptional activation of the metastasis-associated C4.4A gene. Int J Cancer (2007) 0.83
A 3'UTR polymorphism modulates mRNA stability of the oncogene and drug target Polo-like Kinase 1. Mol Cancer (2014) 0.82
High S100A8 and S100A12 protein expression is a favorable prognostic factor for survival of oropharyngeal squamous cell carcinoma. Int J Cancer (2014) 0.82
Targeting EGFR-PI3K-AKT-mTOR signaling enhances radiosensitivity in head and neck squamous cell carcinoma. Expert Opin Ther Targets (2015) 0.82
AP-1-controlled hepatocyte growth factor activation promotes keratinocyte migration via CEACAM1 and urokinase plasminogen activator/urokinase plasminogen receptor. J Invest Dermatol (2008) 0.82
JunB is required for IgE-mediated degranulation and cytokine release of mast cells. J Immunol (2007) 0.82
Keratinocyte-specific deletion of the receptor RAGE modulates the kinetics of skin inflammation in vivo. J Invest Dermatol (2013) 0.81
Impaired skin regeneration and remodeling after cutaneous injury and chemically induced hyperplasia in taps-transgenic mice. J Invest Dermatol (2010) 0.81
Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation. BMC Genomics (2010) 0.81
Parathyroid hormone inhibits c-Jun N-terminal kinase activity in rat osteoblastic cells by a protein kinase A-dependent pathway. Endocrinology (2002) 0.81
Enhanced StefinA and Sprr2 expression during papilloma formation in HPV8 transgenic mice. J Dermatol Sci (2011) 0.81
Assessment of hepatic ischemia-reperfusion injury by simultaneous measurement of tissue pO2, pCO2, and pH. Microvasc Res (2004) 0.81
Attenuation of proinflammatory gene expression and microcirculatory disturbances by endothelin A receptor blockade after orthotopic liver transplantation in pigs. Surgery (2006) 0.81
Stathmin regulates keratinocyte proliferation and migration during cutaneous regeneration. PLoS One (2013) 0.80
Phosphorylation of AKT(Ser473) serves as an independent prognostic marker for radiosensitivity in advanced head and neck squamous cell carcinoma. Int J Cancer (2014) 0.80