On the mechanism of palmitic acid-induced apoptosis: the role of a pore induced by palmitic acid and Ca2+ in mitochondria.

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Published in J Bioenerg Biomembr on July 18, 2006

Authors

Konstantin Belosludtsev1, Nils-Erik L Saris, Leif C Andersson, Natalia Belosludtseva, Alexey Agafonov, Ankit Sharma, Dmitry A Moshkov, Galina D Mironova

Author Affiliations

1: Institute of Theoretical and Experimental Biophysics RAS, Pushchino, Moscow Region, 142290, Russia.

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Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91

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Mitochondrial contact sites. Lipid composition and dynamics. J Biol Chem (1990) 2.10

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[Lipid pores and stability of cell membranes]. Vestn Ross Akad Med Nauk (1995) 0.77

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