Published in Exp Cell Res on June 22, 2006
Epigenetics and environmental chemicals. Curr Opin Pediatr (2009) 2.83
Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium. Chem Res Toxicol (2007) 2.59
Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers. J Biol Chem (2009) 1.17
Environmental epigenetics in metal exposure. Epigenetics (2011) 1.08
Elucidating the mechanisms of nickel compound uptake: a review of particulate and nano-nickel endocytosis and toxicity. Toxicol Appl Pharmacol (2011) 0.94
The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2012) 0.91
A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae. BMC Genomics (2009) 0.81
SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage. Genes Dev (2012) 1.90
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress. J Biol Chem (2004) 1.85
Low level, long-term inorganic arsenite exposure causes generalized resistance to apoptosis in cultured human keratinocytes: potential role in skin co-carcinogenesis. Int J Cancer (2005) 1.21
Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel. J Cell Biochem (2006) 1.10
Ascorbate depletion: a critical step in nickel carcinogenesis? Environ Health Perspect (2005) 1.04
Inhibition of core histones acetylation by carcinogenic nickel(II). Mol Cell Biochem (2005) 0.98
The role of ascorbate in the modulation of HIF-1alpha protein and HIF-dependent transcription by chromium(VI) and nickel(II). Free Radic Biol Med (2007) 0.97
DNA damage, superoxide, and mutant K-ras in human lung adenocarcinoma cells. Free Radic Biol Med (2007) 0.92
Ontogeny-driven rDNA rearrangement, methylation, and transcription, and paternal influence. PLoS One (2011) 0.91
Induction of oxidative DNA damage by carcinogenic metals. Toxicol Lett (2002) 0.90
Truncation, deamidation, and oxidation of histone H2B in cells cultured with nickel(II). Chem Res Toxicol (2005) 0.89
Regulation of hypoxia-inducible genes by ETS1 transcription factor. Carcinogenesis (2008) 0.89
Effects of selenium supplementation on expression of glutathione peroxidase isoforms in cultured human lung adenocarcinoma cell lines. Lung Cancer (2006) 0.89
Nickel(II)-induced apoptosis in murine T cell hybridoma cells is associated with increased fas ligand expression. Toxicol Appl Pharmacol (2002) 0.87
Hypersusceptibility to cisplatin carcinogenicity in metallothionein-I/II double knockout mice: production of hepatocellular carcinoma at clinically relevant doses. Int J Cancer (2006) 0.87
Gestation stage-specific oxidative deoxyribonucleic acid damage from sidestream smoke in pregnant rats and their fetuses. Arch Environ Health (2003) 0.83
Microarray analysis of altered gene expression in murine fibroblasts transformed by nickel(II) to nickel(II)-resistant malignant phenotype. Toxicol Appl Pharmacol (2005) 0.83
Quantum chemical modeling of reaction mechanism for 2-oxoglutarate dependent enzymes: effect of substitution of iron by nickel and cobalt. J Phys Chem A (2006) 0.82
The octapeptidic end of the C-terminal tail of histone H2A is cleaved off in cells exposed to carcinogenic nickel(II). Chem Res Toxicol (2003) 0.82
Reduced Fhit protein expression in nickel-transformed mouse cells and in nickel-induced murine sarcomas. Mol Cell Biochem (2004) 0.82
Microarray analysis of altered gene expression in the TM4 Sertoli-like cell line exposed to chromium(III) chloride. Reprod Toxicol (2002) 0.82
Gene expression dose-response changes in microarrays after exposure of human peripheral lung epithelial cells to nickel(II). Toxicol Appl Pharmacol (2003) 0.81
In vitro inhibition of the enzymatic activity of tumor suppressor FHIT gene product by carcinogenic transition metals. Chem Res Toxicol (2002) 0.80
Metal ions-stimulated iron oxidation in hydroxylases facilitates stabilization of HIF-1 alpha protein. Toxicol Sci (2008) 0.79
Increased serum corticosterone and glucose in offspring of chromium(III)-treated male mice. Environ Health Perspect (2002) 0.78
Inhibition of prolidase activity by nickel causes decreased growth of proline auxotrophic CHO cells. J Cell Biochem (2005) 0.78
Truncation of histone H2A's C-terminal tail, as is typical for Ni(II)-assisted specific peptide bond hydrolysis, has gene expression altering effects. Ann Clin Lab Sci (2009) 0.78
Molecular and organismal changes in offspring of male mice treated with chemical stressors. Environ Mol Mutagen (2012) 0.78
Inhibition of 8-oxo-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) activity of the antimutagenic human MTH1 protein by nucleoside 5'-diphosphates. Free Radic Biol Med (2003) 0.78
Genotoxicity of metal ions: chemical insights. Met Ions Life Sci (2011) 0.78
Metallothionein-I/II double knockout mice are no more sensitive to the carcinogenic effects of nickel subsulfide than wild-type mice. Int J Toxicol (2005) 0.78
Determination of the stability constants and oxidation susceptibility of nickel(II) complexes with 2'-deoxyguanosine 5'-triphosphate and L-histidine. J Inorg Biochem (2005) 0.76
Marked liver tumorigenesis by Helicobacter hepaticus requires perinatal exposure. Environ Health Perspect (2008) 0.75
Up-regulation of 8-oxo-dGTPase activity of MTH1 protein in the brain, testes and kidneys of mice exposed to (137)Cs gamma radiation. Radiat Res (2009) 0.75
Cellular 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase activity of human and mouse MTH1 proteins does not depend on the proliferation rate. Free Radic Biol Med (2004) 0.75
Coordination mode and oxidation susceptibility of nickel(II) complexes with 2'-deoxyguanosine 5'-monophosphate and l-histidine. J Inorg Biochem (2004) 0.75
Minimal influence of metallothionein over-expression on nickel carcinogenesis in mice. Toxicol Lett (2004) 0.75