Published in Int J Pharm on June 27, 2006
Tyrosine-based rivastigmine-loaded organogels in the treatment of Alzheimer's disease. Biomaterials (2010) 0.92
Pharmacokinetic and pharmacodynamic profiles of recombinant human erythropoietin-loaded poly(lactic-co-glycolic acid) microspheres in rats. Acta Pharmacol Sin (2011) 0.83
In vitro-in vivo correlation for complex non-oral drug products: Where do we stand? J Control Release (2015) 0.79
In vitro-in vivo correlation of parenteral risperidone polymeric microspheres. J Control Release (2015) 0.77
A reproducible accelerated in vitro release testing method for PLGA microspheres. Int J Pharm (2015) 0.77
HMGB1 promotes drug resistance in osteosarcoma. Cancer Res (2011) 2.82
An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules. Cell (2013) 2.30
Drs2p-dependent formation of exocytic clathrin-coated vesicles in vivo. Curr Biol (2002) 1.75
c-kit is required for cardiomyocyte terminal differentiation. Circ Res (2008) 1.58
SATB1 is an independent prognostic marker for gastric cancer in a Chinese population. Oncol Rep (2010) 1.56
Association of complement factor H polymorphisms with exudative age-related macular degeneration. Mol Vis (2006) 1.41
Adoptive cell therapy for patients with melanoma, using tumor-infiltrating lymphocytes genetically engineered to secrete interleukin-2. Hum Gene Ther (2008) 1.38
Expression of SATB1 and heparanase in gastric cancer and its relationship to clinicopathologic features. APMIS (2010) 1.37
Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action. Mol Cancer (2009) 1.35
Roles for the Drs2p-Cdc50p complex in protein transport and phosphatidylserine asymmetry of the yeast plasma membrane. Traffic (2006) 1.31
Hospital nursing, care quality, and patient satisfaction: cross-sectional surveys of nurses and patients in hospitals in China and Europe. Int J Nurs Stud (2012) 1.28
Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats. Neurosci Lett (2005) 1.28
The Arf activator Gea2p and the P-type ATPase Drs2p interact at the Golgi in Saccharomyces cerevisiae. J Cell Sci (2004) 1.25
The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death. J Biol Chem (2003) 1.24
Anti-inflammatory role of IL-17 in experimental autoimmune uveitis. J Immunol (2009) 1.23
Regulation of a Golgi flippase by phosphoinositides and an ArfGEF. Nat Cell Biol (2009) 1.23
δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders. J Biol Chem (2012) 1.23
Desmosomal cadherin misexpression alters beta-catenin stability and epidermal differentiation. Mol Cell Biol (2005) 1.21
Multiple gene polymorphisms in the complement factor h gene are associated with exudative age-related macular degeneration in chinese. Invest Ophthalmol Vis Sci (2008) 1.21
Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma. Autophagy (2012) 1.19
Involvement of chymase-mediated angiotensin II generation in blood pressure regulation. J Clin Invest (2004) 1.18
Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff-Parkinson-White syndrome. Am J Physiol Heart Circ Physiol (2005) 1.14
In vitro anti-inflammatory effects of arctigenin, a lignan from Arctium lappa L., through inhibition on iNOS pathway. J Ethnopharmacol (2009) 1.13
One step isolation and purification of liquiritigenin and isoliquiritigenin from Glycyrrhiza uralensis Risch. using high-speed counter-current chromatography. J Chromatogr A (2005) 1.10
Investigation of a transgenic mouse model of familial dilated cardiomyopathy. J Mol Cell Cardiol (2010) 1.10
Association of polymorphisms of tumor necrosis factor and tumor protein p53 with primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2010) 1.09
Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development. Proc Natl Acad Sci U S A (2013) 1.08
U.S. Food and Drug Administration approval: vismodegib for recurrent, locally advanced, or metastatic basal cell carcinoma. Clin Cancer Res (2013) 1.06
Control of protein and sterol trafficking by antagonistic activities of a type IV P-type ATPase and oxysterol binding protein homologue. Mol Biol Cell (2009) 1.06
Molecular epidemiology of rabies in Guangxi Province, south of China. J Clin Virol (2007) 1.05
Icaritin causes sustained ERK1/2 activation and induces apoptosis in human endometrial cancer cells. PLoS One (2011) 1.05
Expression of beta2-adrenergic receptor in oral squamous cell carcinoma. J Oral Pathol Med (2008) 1.04
Neuroprotective effects of hydroxysafflor yellow A: in vivo and in vitro studies. Planta Med (2003) 1.03
A despecialization step underlying evolution of a family of serine proteases. Mol Cell (2003) 1.03
Genetic associations in polypoidal choroidal vasculopathy: a systematic review and meta-analysis. Mol Vis (2012) 0.99
Nurse staffing levels make a difference on patient outcomes: a multisite study in Chinese hospitals. J Nurs Scholarsh (2012) 0.99
Therapeutic effects of hydroxysafflor yellow A on focal cerebral ischemic injury in rats and its primary mechanisms. J Asian Nat Prod Res (2005) 0.98
Anti-tumor activities of andrographolide, a diterpene from Andrographis paniculata, by inducing apoptosis and inhibiting VEGF level. J Asian Nat Prod Res (2008) 0.98
Inhibition of LDH-A by lentivirus-mediated small interfering RNA suppresses intestinal-type gastric cancer tumorigenicity through the downregulation of Oct4. Cancer Lett (2012) 0.98
ScafBank: a public comprehensive Scaffold database to support molecular hopping. Acta Pharmacol Sin (2009) 0.97
Cardioprotective effects of salvianolic Acid a on myocardial ischemia-reperfusion injury in vivo and in vitro. Evid Based Complement Alternat Med (2011) 0.96
Rare cancer trial design: lessons from FDA approvals. Clin Cancer Res (2012) 0.96
Transgenic overexpression of LARGE induces α-dystroglycan hyperglycosylation in skeletal and cardiac muscle. PLoS One (2010) 0.95
Ginsenoside Rh(2) enhances antitumour activity and decreases genotoxic effect of cyclophosphamide. Basic Clin Pharmacol Toxicol (2006) 0.94
ER-α36, a novel variant of ER-α, mediates estrogen-stimulated proliferation of endometrial carcinoma cells via the PKCδ/ERK pathway. PLoS One (2010) 0.94
Antiplatelet and antithrombotic activities of salvianolic acid A. Thromb Res (2010) 0.94
Evaluation of 2-thioxo-2,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidin-4(1H)-one analogues as GAA activators. Eur J Med Chem (2010) 0.94
Folotyn (pralatrexate injection) for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma: U.S. Food and Drug Administration drug approval summary. Clin Cancer Res (2010) 0.93
Ginsenoside 20(S)-protopanaxadiol inhibits the proliferation and invasion of human fibrosarcoma HT1080 cells. Basic Clin Pharmacol Toxicol (2006) 0.93
Escin: inhibiting inflammation and promoting gastrointestinal transit to attenuate formation of postoperative adhesions. World J Surg (2005) 0.93
Evaluations of the selectivities of the diacylglycerol kinase inhibitors R59022 and R59949 among diacylglycerol kinase isozymes using a new non-radioactive assay method. Pharmacology (2013) 0.92
High throughput screening for inhibitors of alpha-galactosidase. Curr Chem Genomics (2010) 0.92
Klotho upregulation contributes to the neuroprotection of ligustilide in an Alzheimer's disease mouse model. Neurobiol Aging (2013) 0.91
DrugViz: a Cytoscape plugin for visualizing and analyzing small molecule drugs in biological networks. Bioinformatics (2008) 0.91
Delta tryptase is expressed in multiple human tissues, and a recombinant form has proteolytic activity. J Immunol (2002) 0.91
Visualization of nitroxyl in living cells by a chelated copper(II) coumarin complex. Org Lett (2011) 0.90
Effect of alpha1-adrenergic antagonists on lower ureteral stones with extracorporeal shock wave lithotripsy. Asian J Surg (2010) 0.90
The subchronic toxicity of hydroxysafflor yellow A of 90 days repeatedly intraperitoneal injections in rats. Toxicology (2004) 0.90
Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan. Aging Cell (2013) 0.90
Extended active optical lattice filters: filter synthesis. J Opt Soc Am A Opt Image Sci Vis (2010) 0.89
A high throughput glucocerebrosidase assay using the natural substrate glucosylceramide. Anal Bioanal Chem (2011) 0.89
A new resorufin-based alpha-glucosidase assay for high-throughput screening. Anal Biochem (2009) 0.89
[Protective effect of hydroxysafflor yellow A on experimental cerebral ischemia in rats]. Yao Xue Xue Bao (2005) 0.89
Inhibiting autophagy potentiates the anticancer activity of IFN1@/IFNα in chronic myeloid leukemia cells. Autophagy (2012) 0.89
Indole alkoloids from Nauclea officinalis with weak antimalarial activity. Phytochemistry (2008) 0.88
Association of C2 and CFB polymorphisms with anterior uveitis. Invest Ophthalmol Vis Sci (2012) 0.88
Posterior decompression and short segmental pedicle screw fixation combined with vertebroplasty for Kümmell's disease with neurological deficits. Exp Ther Med (2012) 0.88
Synthesis and characterization of a new fluorogenic substrate for alpha-galactosidase. Anal Bioanal Chem (2009) 0.88
Identification of a repressor in the first intron of the human alpha2(I) collagen gene (COL1A2). J Biol Chem (2005) 0.88
A phenotypic compound screening assay for lysosomal storage diseases. J Biomol Screen (2013) 0.87
Role of a 5'-enhancer in the transcriptional regulation of the human endothelial cell protein C receptor gene. Blood (2006) 0.87
EphA2/ephrinA1 mRNA expression and protein production in adenoid cystic carcinoma of salivary gland. J Oral Maxillofac Surg (2013) 0.87
Down-regulated SPARCL1 is associated with clinical significance in human gastric cancer. J Surg Oncol (2011) 0.87
Adsorption of nitrobenzene from aqueous solution by MCM-41. J Colloid Interface Sci (2007) 0.86
A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats. J Neurosci (2013) 0.86
Cooperativity between far upstream enhancer and proximal promoter elements of the human {alpha}2(I) collagen (COL1A2) gene instructs tissue specificity in transgenic mice. J Biol Chem (2004) 0.86
Long noncoding RNA-LET, which is repressed by EZH2, inhibits cell proliferation and induces apoptosis of nasopharyngeal carcinoma cell. Med Oncol (2015) 0.85
Use of blood urea nitrogen, creatinine, interleukin-6, granulocyte-macrophage colony stimulating factor in combination to predict the severity and outcome of abdominal sepsis in rats. Inflamm Res (2012) 0.85
Expression of chemokine receptor CCR7 is associated with cervical lymph node metastasis of oral squamous cell carcinoma. Oral Oncol (2008) 0.85
Interleukin-11 promotes the progress of gastric carcinoma via abnormally expressed versican. Int J Biol Sci (2012) 0.85
Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-κB and STAT3 in transient focal stroke. PLoS One (2013) 0.85
Is Intracranial Pressure Monitoring of Patients With Diffuse Traumatic Brain Injury Valuable? An Observational Multicenter Study. Neurosurgery (2016) 0.84
Chemical-assisted bonding of thermoplastics/elastomer for fabricating microfluidic valves. Anal Chem (2010) 0.84
Single-layer MoS2 nanopores as nanopower generators. Nature (2016) 0.84
Adsorption of anionic dyes on ammonium-functionalized MCM-41. J Hazard Mater (2008) 0.83
Metabolism of salvianolic acid A and antioxidant activities of its methylated metabolites. Drug Metab Dispos (2013) 0.83
Neuroprotective effects of safflor yellow B on brain ischemic injury. Exp Brain Res (2006) 0.82
Enhanced antitumor efficacy and reduced systemic toxicity of sulfatide-containing nanoliposomal doxorubicin in a xenograft model of colorectal cancer. PLoS One (2012) 0.82
Effects of ligustilide on lipopolysaccharide-induced endotoxic shock in rabbits. Planta Med (2010) 0.82
Association of genetic variants on 8p21 and 4q12 with age-related macular degeneration in Asian populations. Invest Ophthalmol Vis Sci (2012) 0.82
[Effect of nucleolin down-regulation on the proliferation and apoptosis in C2C12 cells]. Zhong Nan Da Xue Xue Bao Yi Xue Ban (2005) 0.82
Five new neo-clerodane diterpenoid alkaloids from Scutellaria barbata with cytotoxic activities. Chem Pharm Bull (Tokyo) (2007) 0.82
Primary meningeal melanocytoma located in foramen magnum: a case report and review of the literatures. Chin Med Sci J (2012) 0.82
Selective Modulation of Gq/Gs pathways by Naphtho Pyrano Pyrimidines as antagonists of the Neuropeptide S Receptor. ACS Chem Neurosci (2010) 0.82
Reduction-sensitive dual functional nanomicelles for improved delivery of paclitaxel. Bioconjug Chem (2014) 0.82
The glutathione S-transferase P1 341C>T polymorphism and cancer risk: a meta-analysis of 28 case-control studies. PLoS One (2013) 0.81
A high-throughput sphingomyelinase assay using natural substrate. Anal Bioanal Chem (2012) 0.81
Inferring protein function by domain context similarities in protein-protein interaction networks. BMC Bioinformatics (2009) 0.81
GSK3beta modulates PACAP-induced neuritogenesis in PC12 cells by acting downstream of Rap1 in a caveolae-dependent manner. Cell Signal (2008) 0.81
Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation. J Biol Chem (2008) 0.81