PubRank

Glenn Merlino

Author PubWeight™ 74.09‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Interferon-γ links ultraviolet radiation to melanomagenesis in mice. Nature 2011 3.56
2 Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects. J Clin Invest 2002 3.24
3 Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Nat Med 2004 2.90
4 Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis. Nat Med 2002 2.58
5 The two faces of interferon-γ in cancer. Clin Cancer Res 2011 2.20
6 Uncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAF. PLoS One 2009 2.03
7 Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment. Nat Commun 2012 1.90
8 Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF. Sci Signal 2011 1.90
9 Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models. J Clin Invest 2009 1.83
10 A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway. Cell 2013 1.75
11 ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence. Proc Natl Acad Sci U S A 2007 1.61
12 Ultraviolet B but not ultraviolet A radiation initiates melanoma. Cancer Res 2004 1.57
13 Murine rhabdomyosarcoma is immunogenic and responsive to T-cell-based immunotherapy. Pediatr Blood Cancer 2011 1.53
14 The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis. Cancer Res 2006 1.52
15 MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism. PLoS One 2009 1.40
16 Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, ATF-2 and cyclin D1. Oncogene 2002 1.40
17 MicroRNA reexpression as differentiation therapy in cancer. J Clin Invest 2009 1.38
18 Modeling metastasis biology and therapy in real time in the mouse lung. J Clin Invest 2010 1.32
19 Obligate roles for p16(Ink4a) and p19(Arf)-p53 in the suppression of murine pancreatic neoplasia. Mol Cell Biol 2002 1.28
20 Ink4a/arf deficiency promotes ultraviolet radiation-induced melanomagenesis. Cancer Res 2002 1.24
21 Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models. Clin Cancer Res 2007 1.22
22 Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39. Am J Hum Genet 2009 1.21
23 Ultraviolet radiation and cutaneous malignant melanoma. Oncogene 2003 1.17
24 Progress in cutaneous cancer research. J Investig Dermatol Symp Proc 2002 1.16
25 Constitutive c-Met signaling through a nonautocrine mechanism promotes metastasis in a transgenic transplantation model. Cancer Res 2002 1.14
26 Hepatocyte growth factor/scatter factor induces feedback up-regulation of CD44v6 in melanoma cells through Egr-1. Cancer Res 2003 1.13
27 Lentivirus-mediated bifunctional cell labeling for in vivo melanoma study. Pigment Cell Melanoma Res 2009 1.12
28 Hepatocyte growth factor promotes hepatocarcinogenesis through c-Met autocrine activation and enhanced angiogenesis in transgenic mice treated with diethylnitrosamine. Oncogene 2002 1.06
29 VEGF contributes to mammary tumor growth in transgenic mice through paracrine and autocrine mechanisms. Lab Invest 2005 1.04
30 Testing of new agents in childhood cancer preclinical models: meeting summary. Clin Cancer Res 2002 1.03
31 Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis. Proc Natl Acad Sci U S A 2002 0.99
32 From UVs to metastases: modeling melanoma initiation and progression in the mouse. J Invest Dermatol 2008 0.97
33 Animal models of melanoma: an HGF/SF transgenic mouse model may facilitate experimental access to UV initiating events. Pigment Cell Res 2003 0.97
34 Melanomagenesis: overcoming the barrier of melanocyte senescence. Cell Cycle 2008 0.97
35 Rapid growth of invasive metastatic melanoma in carcinogen-treated hepatocyte growth factor/scatter factor-transgenic mice carrying an oncogenic CDK4 mutation. Am J Pathol 2006 0.91
36 Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene. PLoS One 2010 0.91
37 Preclinical therapeutic response of residual metastatic disease is distinct from its primary tumor of origin. Int J Cancer 2011 0.91
38 p53 loss increases the osteogenic differentiation of bone marrow stromal cells. Stem Cells 2015 0.83
39 In vivo role of alternative splicing and serine phosphorylation of the microphthalmia-associated transcription factor. Genetics 2012 0.83
40 Building the perfect beast: complex mouse models teach surprisingly simple melanoma lessons. Pigment Cell Melanoma Res 2009 0.82
41 A traitor in our midst: mesenchymal stem cells contribute to tumor progression and metastasis. Future Oncol 2008 0.82
42 NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma. Clin Exp Metastasis 2012 0.81
43 Selenium and selenoprotein deficiencies induce widespread pyogranuloma formation in mice, while high levels of dietary selenium decrease liver tumor size driven by TGFα. PLoS One 2013 0.81
44 A genetically engineered mouse model with inducible GFP expression in melanocytes. Pigment Cell Melanoma Res 2011 0.81
45 Sunscreen prevention of melanoma in man and mouse. Pigment Cell Melanoma Res 2010 0.81
46 Overexpression of NK2 inhibits liver regeneration after partial hepatectomy in mice. World J Gastroenterol 2005 0.80
47 TGFbeta1 and TGFalpha contrarily affect alveolar survival and tumorigenesis in mouse mammary epithelium. Int J Cancer 2007 0.79
48 Meeting report: fourth international congress of the Society for Melanoma Research. Pigment Cell Melanoma Res 2008 0.79
49 Shedding light on melanocyte pathobiology in vivo. Cancer Res 2012 0.78
50 Imaging melanoma in a murine model using reflectance-mode confocal scanning laser microscopy and polarized light imaging. J Investig Dermatol Symp Proc 2005 0.78
51 Noninvasive imaging of melanoma with reflectance mode confocal scanning laser microscopy in a murine model. J Invest Dermatol 2007 0.78
52 Illuminating progression: tracking melanoma metastasis in a gene therapy setting. Pigment Cell Melanoma Res 2011 0.77
53 Roles for aberrant CXCR3 signaling in basal cell carcinoma: a case for dual activity. Am J Pathol 2010 0.76
54 Animal models of melanoma. J Investig Dermatol Symp Proc 2005 0.76
55 Modeling the transcriptional consequences of epidermal growth factor receptor ablation in Ras-initiated squamous cancer. Clin Cancer Res 2011 0.76
56 The ARFul truth about melanoma susceptibility genes. Pigment Cell Melanoma Res 2007 0.76
57 Fluorescent protein-assisted purification for gene expression profiling. Methods Mol Biol 2011 0.76
58 Chemoprevention of melanoma. Curr Oncol Rep 2004 0.75
59 A melanin-independent interaction between Mc1r and Met signaling pathways is required for HGF-dependent melanoma. Int J Cancer 2014 0.75
60 β-catenin in metastatic melanoma--the smoking gun reloaded. Pigment Cell Melanoma Res 2012 0.75
61 Cancer biology: the weakest link? Nature 2005 0.75
62 Unraveling the melanoma pathogenome. Pigment Cell Melanoma Res 2012 0.75
63 Lymphangiogenesis: From passive disseminator to dynamic metastatic enabler. Pigment Cell Melanoma Res 2017 0.75
64 Flipping the phenotypic switch on a novel antimelanoma differentiation strategy. Pigment Cell Melanoma Res 2013 0.75