Bistability in bacteria.

Noise in gene expression determines cell fate in Bacillus subtilis. Science (2007) 7.45

Control of cell fate by the formation of an architecturally complex bacterial community. Genes Dev (2008) 3.92

Bistability and biofilm formation in Bacillus subtilis. Mol Microbiol (2007) 3.83

A stochastic single-molecule event triggers phenotype switching of a bacterial cell. Science (2008) 3.46

Central dogma at the single-molecule level in living cells. Nature (2011) 3.00

cis-antisense RNA, another level of gene regulation in bacteria. Microbiol Mol Biol Rev (2011) 2.78

Sticking together: building a biofilm the Bacillus subtilis way. Nat Rev Microbiol (2013) 2.68

Molecular control of bacterial death and lysis. Microbiol Mol Biol Rev (2008) 2.52

Thinking about Bacillus subtilis as a multicellular organism. Curr Opin Microbiol (2007) 2.48

Microanatomy at cellular resolution and spatial order of physiological differentiation in a bacterial biofilm. MBio (2013) 2.43

Origins of regulated cell-to-cell variability. Nat Rev Mol Cell Biol (2011) 2.15

Recent progress in Bacillus subtilis sporulation. FEMS Microbiol Rev (2011) 2.12

Protein sequestration generates a flexible ultrasensitive response in a genetic network. Mol Syst Biol (2009) 2.09

Modes of response to environmental change and the elusive empirical evidence for bet hedging. Proc Biol Sci (2011) 2.04

Single-cell protein induction dynamics reveals a period of vulnerability to antibiotics in persister bacteria. Proc Natl Acad Sci U S A (2008) 1.98

Signal integration in bacterial two-component regulatory systems. Genes Dev (2008) 1.93

Peptide alarmone signalling triggers an auto-active bacteriocin necessary for genetic competence. Mol Microbiol (2009) 1.91

Paracrine signaling in a bacterium. Genes Dev (2009) 1.83

Positive feedback in cellular control systems. Bioessays (2008) 1.79

A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence. Nucleic Acids Res (2012) 1.70

Deciding fate in adverse times: sporulation and competence in Bacillus subtilis. Proc Natl Acad Sci U S A (2009) 1.65

Transient heterogeneity in extracellular protease production by Bacillus subtilis. Mol Syst Biol (2008) 1.60

Broadly heterogeneous activation of the master regulator for sporulation in Bacillus subtilis. Proc Natl Acad Sci U S A (2010) 1.56

Molecular level stochastic model for competence cycles in Bacillus subtilis. Proc Natl Acad Sci U S A (2007) 1.54

Heterogeneous bacterial persisters and engineering approaches to eliminate them. Curr Opin Microbiol (2011) 1.47

Subpopulation-specific transcriptome analysis of competence-stimulating-peptide-induced Streptococcus mutans. J Bacteriol (2011) 1.47

Dynamics in the mixed microbial concourse. Genes Dev (2010) 1.45

Live Cell Imaging of Bacillus subtilis and Streptococcus pneumoniae using Automated Time-lapse Microscopy. J Vis Exp (2011) 1.43

Complexity in bacterial cell-cell communication: quorum signal integration and subpopulation signaling in the Bacillus subtilis phosphorelay. Proc Natl Acad Sci U S A (2009) 1.42

To be or not to be: regulation of restriction-modification systems and other toxin-antitoxin systems. Nucleic Acids Res (2013) 1.42

Cell division in Escherichia coli cultures monitored at single cell resolution. BMC Microbiol (2008) 1.41

Mass spectrometry-based metabolomics of single yeast cells. Proc Natl Acad Sci U S A (2013) 1.41

Evolution of stochastic switching rates in asymmetric fitness landscapes. Genetics (2009) 1.40

Stress-induced phenotypic switching in Candida albicans. Mol Biol Cell (2009) 1.37

Automated imaging with ScanLag reveals previously undetectable bacterial growth phenotypes. Nat Methods (2010) 1.36

Memory and modularity in cell-fate decision making. Nature (2013) 1.36

Role of the sigmaD-dependent autolysins in Bacillus subtilis population heterogeneity. J Bacteriol (2009) 1.35

The innate growth bistability and fitness landscapes of antibiotic-resistant bacteria. Science (2013) 1.34

A microscope automated fluidic system to study bacterial processes in real time. PLoS One (2009) 1.33

The EAL domain protein YciR acts as a trigger enzyme in a c-di-GMP signalling cascade in E. coli biofilm control. EMBO J (2013) 1.32

A bistable switch and anatomical site control Vibrio cholerae virulence gene expression in the intestine. PLoS Pathog (2010) 1.32

Positive feedback and noise activate the stringent response regulator rel in mycobacteria. PLoS One (2008) 1.30

Levels of Ca2+-dipicolinic acid in individual bacillus spores determined using microfluidic Raman tweezers. J Bacteriol (2007) 1.30

Intrinsic and Extrinsic Regulation of Type III Secretion Gene Expression in Pseudomonas Aeruginosa. Front Microbiol (2011) 1.29

Mode of expression and functional characterization of FCT-3 pilus region-encoded proteins in Streptococcus pyogenes serotype M49. Infect Immun (2008) 1.28

Hysteretic and graded responses in bacterial two-component signal transduction. Mol Microbiol (2008) 1.26

Programmed heterogeneity: epigenetic mechanisms in bacteria. J Biol Chem (2013) 1.25

Pre-dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch. Mol Syst Biol (2010) 1.24

Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureus. PLoS Genet (2013) 1.23

Heterochronic phosphorelay gene expression as a source of heterogeneity in Bacillus subtilis spore formation. J Bacteriol (2010) 1.23

Memory in microbes: quantifying history-dependent behavior in a bacterium. PLoS One (2008) 1.22

Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype. Proc Natl Acad Sci U S A (2013) 1.22

Bet-hedging during bacterial diauxic shift. Proc Natl Acad Sci U S A (2014) 1.21

Bistable expression of CsgD in biofilm development of Salmonella enterica serovar typhimurium. J Bacteriol (2009) 1.19

Microbial virulence as an emergent property: consequences and opportunities. PLoS Pathog (2011) 1.16

A short story about a big magic bug. Bioeng Bugs (2010) 1.16

Microbial scout hypothesis, stochastic exit from dormancy, and the nature of slow growers. Appl Environ Microbiol (2012) 1.15

Is bacterial persistence a social trait? PLoS One (2007) 1.14

Fluctuations in spo0A transcription control rare developmental transitions in Bacillus subtilis. PLoS Genet (2011) 1.13

Diversity in ATP concentrations in a single bacterial cell population revealed by quantitative single-cell imaging. Sci Rep (2014) 1.12

Building biological memory by linking positive feedback loops. Proc Natl Acad Sci U S A (2009) 1.12

Mutability and importance of a hypermutable cell subpopulation that produces stress-induced mutants in Escherichia coli. PLoS Genet (2008) 1.12

Reversal of an epigenetic switch governing cell chaining in Bacillus subtilis by protein instability. Mol Microbiol (2010) 1.12

Clp-dependent proteolysis down-regulates central metabolic pathways in glucose-starved Bacillus subtilis. J Bacteriol (2007) 1.11

Evolution of microbes and viruses: a paradigm shift in evolutionary biology? Front Cell Infect Microbiol (2012) 1.11

A novel factor controlling bistability in Bacillus subtilis: the YmdB protein affects flagellin expression and biofilm formation. J Bacteriol (2011) 1.10

Noise in biology. Rep Prog Phys (2014) 1.09

Hyperosmotic stress response of Campylobacter jejuni. J Bacteriol (2012) 1.09

DprA/Smf protein localizes at the DNA uptake machinery in competent Bacillus subtilis cells. BMC Microbiol (2007) 1.08

Bistable responses in bacterial genetic networks: designs and dynamical consequences. Math Biosci (2011) 1.08

Regulation of phenotypic heterogeneity permits Salmonella evasion of the host caspase-1 inflammatory response. Proc Natl Acad Sci U S A (2011) 1.08

The evolutionary emergence of stochastic phenotype switching in bacteria. Microb Cell Fact (2011) 1.07

Induction of natural competence in Bacillus cereus ATCC14579. Microb Biotechnol (2008) 1.07

The threshold level of the sensor histidine kinase KinA governs entry into sporulation in Bacillus subtilis. J Bacteriol (2010) 1.07

Contribution of phenotypic heterogeneity to adaptive antibiotic resistance. Proc Natl Acad Sci U S A (2013) 1.07

Culture history and population heterogeneity as determinants of bacterial adaptation: the adaptomics of a single environmental transition. Microbiol Mol Biol Rev (2012) 1.07

Variation in Candida albicans EFG1 expression enables host-dependent changes in colonizing fungal populations. MBio (2012) 1.06

The role of coupled positive feedback in the expression of the SPI1 type three secretion system in Salmonella. PLoS Pathog (2010) 1.06

Regulation of the Salmonella enterica std fimbrial operon by DNA adenine methylation, SeqA, and HdfR. J Bacteriol (2008) 1.06

Reversible and noisy progression towards a commitment point enables adaptable and reliable cellular decision-making. PLoS Comput Biol (2011) 1.06

A stress-inducible quorum-sensing peptide mediates the formation of persister cells with noninherited multidrug tolerance. J Bacteriol (2012) 1.05

Exact results for the evolution of stochastic switching in variable asymmetric environments. Genetics (2010) 1.05

Extracellular signaling and multicellularity in Bacillus subtilis. Curr Opin Microbiol (2011) 1.04

An effort to make sense of antisense transcription in bacteria. RNA Biol (2012) 1.04

Epigenetic control of virulence gene expression in Pseudomonas aeruginosa by a LysR-type transcription regulator. PLoS Genet (2009) 1.03

DNA looping in prokaryotes: experimental and theoretical approaches. J Bacteriol (2013) 1.03

Ultrasensitivity of the Bacillus subtilis sporulation decision. Proc Natl Acad Sci U S A (2012) 1.02

Modeling bistable cell-fate choices in the Drosophila eye: qualitative and quantitative perspectives. Development (2010) 1.02

Adaptive noise. Proc Biol Sci (2013) 1.02

Stochasticity and bistability in horizontal transfer control of a genomic island in Pseudomonas. Proc Natl Acad Sci U S A (2008) 1.01

Conservation of Ebp-type pilus genes among Enterococci and demonstration of their role in adherence of Enterococcus faecalis to human platelets. Infect Immun (2011) 1.01

Characterization of an inducible promoter in different DNA copy number conditions. BMC Bioinformatics (2012) 1.01

Self-regulation of exopolysaccharide production in Bacillus subtilis by a tyrosine kinase. Genes Dev (2014) 1.00

The Streptococcus pneumoniae pilus-1 displays a biphasic expression pattern. PLoS One (2011) 0.99

Stress-induced remodeling of the bacterial proteome. Curr Biol (2014) 0.98

Genes regulated by the Escherichia coli SOS repressor LexA exhibit heterogeneous expression. BMC Microbiol (2010) 0.98

A bistable gene switch for antibiotic biosynthesis: the butyrolactone regulon in Streptomyces coelicolor. PLoS One (2008) 0.97

Heritable change caused by transient transcription errors. PLoS Genet (2013) 0.97

Systems glycobiology: biochemical reaction networks regulating glycan structure and function. Glycobiology (2011) 0.97

Transcriptional cross-activation between toxin-antitoxin systems of Escherichia coli. BMC Microbiol (2013) 0.96

Bacterially speaking. Cell (2006) 6.01

Cannibalism by sporulating bacteria. Science (2003) 5.62

A major protein component of the Bacillus subtilis biofilm matrix. Mol Microbiol (2006) 5.09

A master regulator for biofilm formation by Bacillus subtilis. Mol Microbiol (2005) 4.44

The Spo0A regulon of Bacillus subtilis. Mol Microbiol (2003) 4.19

Control of cell fate by the formation of an architecturally complex bacterial community. Genes Dev (2008) 3.92

High- and low-threshold genes in the Spo0A regulon of Bacillus subtilis. J Bacteriol (2005) 3.87

Bistability and biofilm formation in Bacillus subtilis. Mol Microbiol (2007) 3.83

Amyloid fibers provide structural integrity to Bacillus subtilis biofilms. Proc Natl Acad Sci U S A (2010) 3.78

D-amino acids trigger biofilm disassembly. Science (2010) 3.60

RacA, a bacterial protein that anchors chromosomes to the cell poles. Science (2002) 3.44

Swarming motility in undomesticated Bacillus subtilis. Mol Microbiol (2003) 3.39

The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis. PLoS Biol (2004) 3.33

Genome-wide analysis of the stationary-phase sigma factor (sigma-H) regulon of Bacillus subtilis. J Bacteriol (2002) 3.25

Targets of the master regulator of biofilm formation in Bacillus subtilis. Mol Microbiol (2006) 3.21

Asymmetric cell division in B. subtilis involves a spiral-like intermediate of the cytokinetic protein FtsZ. Cell (2002) 3.12

Generating and exploiting polarity in bacteria. Science (2002) 3.06

A widely conserved bacterial cell division protein that promotes assembly of the tubulin-like protein FtsZ. Genes Dev (2002) 3.03

Evidence that entry into sporulation in Bacillus subtilis is governed by a gradual increase in the level and activity of the master regulator Spo0A. Genes Dev (2005) 3.01

Genes involved in formation of structured multicellular communities by Bacillus subtilis. J Bacteriol (2004) 2.86

Cell population heterogeneity during growth of Bacillus subtilis. Genes Dev (2005) 2.81

A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin. Cell (2006) 2.78

Sticking together: building a biofilm the Bacillus subtilis way. Nat Rev Microbiol (2013) 2.68

Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis. J Bacteriol (2003) 2.65

The sigmaE regulon and the identification of additional sporulation genes in Bacillus subtilis. J Mol Biol (2003) 2.59

Structurally diverse natural products that cause potassium leakage trigger multicellularity in Bacillus subtilis. Proc Natl Acad Sci U S A (2008) 2.54

The forespore line of gene expression in Bacillus subtilis. J Mol Biol (2006) 2.52

Thinking about Bacillus subtilis as a multicellular organism. Curr Opin Microbiol (2007) 2.48

Genes governing swarming in Bacillus subtilis and evidence for a phase variation mechanism controlling surface motility. Mol Microbiol (2004) 2.48

Geometric cue for protein localization in a bacterium. Science (2009) 2.27

Ecology and genomics of Bacillus subtilis. Trends Microbiol (2008) 2.22

An open letter to Elias Zerhouni. Science (2005) 2.19

An accessory protein required for anchoring and assembly of amyloid fibres in B. subtilis biofilms. Mol Microbiol (2011) 2.17

Negative membrane curvature as a cue for subcellular localization of a bacterial protein. Proc Natl Acad Sci U S A (2009) 2.12

Does RNA polymerase help drive chromosome segregation in bacteria? Proc Natl Acad Sci U S A (2002) 2.01

An investigation into the compartmentalization of the sporulation transcription factor sigmaE in Bacillus subtilis. Mol Microbiol (2002) 1.86

Tracing the domestication of a biofilm-forming bacterium. J Bacteriol (2011) 1.85

An epigenetic switch governing daughter cell separation in Bacillus subtilis. Genes Dev (2010) 1.85

Paracrine signaling in a bacterium. Genes Dev (2009) 1.83

A novel regulatory protein governing biofilm formation in Bacillus subtilis. Mol Microbiol (2008) 1.74

Cannibalism enhances biofilm development in Bacillus subtilis. Mol Microbiol (2009) 1.68

A sporulation membrane protein tethers the pro-sigmaK processing enzyme to its inhibitor and dictates its subcellular localization. Genes Dev (2002) 1.68

Protein subcellular localization in bacteria. Cold Spring Harb Perspect Biol (2010) 1.62

Bacillus subtilis genome diversity. J Bacteriol (2006) 1.60

Peptide anchoring spore coat assembly to the outer forespore membrane in Bacillus subtilis. Mol Microbiol (2006) 1.58

A novel pathway of intercellular signalling in Bacillus subtilis involves a protein with similarity to a component of type III secretion channels. Mol Microbiol (2008) 1.58

A feeding tube model for activation of a cell-specific transcription factor during sporulation in Bacillus subtilis. Genes Dev (2009) 1.56

Small untranslated RNA antitoxin in Bacillus subtilis. J Bacteriol (2005) 1.49

Subcellular localization of a small sporulation protein in Bacillus subtilis. J Bacteriol (2003) 1.48

Competencies: a cure for pre-med curriculum. Science (2011) 1.47

Evidence for a novel protease governing regulated intramembrane proteolysis and resistance to antimicrobial peptides in Bacillus subtilis. Genes Dev (2006) 1.47

A Bacillus subtilis sensor kinase involved in triggering biofilm formation on the roots of tomato plants. Mol Microbiol (2012) 1.45

Bacillus subtilis biofilm induction by plant polysaccharides. Proc Natl Acad Sci U S A (2013) 1.41

Genes for small, noncoding RNAs under sporulation control in Bacillus subtilis. J Bacteriol (2006) 1.41

Retracted A self-produced trigger for biofilm disassembly that targets exopolysaccharide. Cell (2012) 1.41

Inhibitory effects of D-amino acids on Staphylococcus aureus biofilm development. J Bacteriol (2011) 1.40

Developmental commitment in a bacterium. Cell (2005) 1.35

Peptide inhibitor of cytokinesis during sporulation in Bacillus subtilis. Mol Microbiol (2008) 1.35

Parallel pathways of repression and antirepression governing the transition to stationary phase in Bacillus subtilis. Proc Natl Acad Sci U S A (2008) 1.32

Liquid transport facilitated by channels in Bacillus subtilis biofilms. Proc Natl Acad Sci U S A (2012) 1.32

Paralogous antirepressors acting on the master regulator for biofilm formation in Bacillus subtilis. Mol Microbiol (2009) 1.29

Dynamic patterns of subcellular protein localization during spore coat morphogenesis in Bacillus subtilis. J Bacteriol (2004) 1.29

Defining a centromere-like element in Bacillus subtilis by Identifying the binding sites for the chromosome-anchoring protein RacA. Mol Cell (2005) 1.29

Galactose metabolism plays a crucial role in biofilm formation by Bacillus subtilis. MBio (2012) 1.28

The master regulator for entry into sporulation in Bacillus subtilis becomes a cell-specific transcription factor after asymmetric division. Genes Dev (2003) 1.27

A widely conserved gene cluster required for lactate utilization in Bacillus subtilis and its involvement in biofilm formation. J Bacteriol (2009) 1.25

KinD is a checkpoint protein linking spore formation to extracellular-matrix production in Bacillus subtilis biofilms. MBio (2010) 1.23

Engulfment during sporulation in Bacillus subtilis is governed by a multi-protein complex containing tandemly acting autolysins. Mol Microbiol (2007) 1.20

ATP-driven self-assembly of a morphogenetic protein in Bacillus subtilis. Mol Cell (2008) 1.19

Small genes under sporulation control in the Bacillus subtilis genome. J Bacteriol (2010) 1.17

Evidence that metabolism and chromosome copy number control mutually exclusive cell fates in Bacillus subtilis. EMBO J (2011) 1.16

Spatial regulation of histidine kinases governing biofilm formation in Bacillus subtilis. J Bacteriol (2010) 1.16

D-amino acids indirectly inhibit biofilm formation in Bacillus subtilis by interfering with protein synthesis. J Bacteriol (2013) 1.15

Interspecies interactions that result in Bacillus subtilis forming biofilms are mediated mainly by members of its own genus. Proc Natl Acad Sci U S A (2011) 1.14

The conserved sporulation protein YneE inhibits DNA replication in Bacillus subtilis. J Bacteriol (2009) 1.14

Do mycobacteria produce endospores? Proc Natl Acad Sci U S A (2009) 1.13

Reversal of an epigenetic switch governing cell chaining in Bacillus subtilis by protein instability. Mol Microbiol (2010) 1.12

Respiration control of multicellularity in Bacillus subtilis by a complex of the cytochrome chain with a membrane-embedded histidine kinase. Genes Dev (2013) 1.07

Polar localization and compartmentalization of ClpP proteases during growth and sporulation in Bacillus subtilis. J Bacteriol (2008) 1.07

Evidence for cyclic Di-GMP-mediated signaling in Bacillus subtilis. J Bacteriol (2012) 1.06

Particle/Fluid interface replication as a means of producing topographically patterned polydimethylsiloxane surfaces for deposition of lipid bilayers. Adv Mater (2010) 1.02

The biocide chlorine dioxide stimulates biofilm formation in Bacillus subtilis by activation of the histidine kinase KinC. J Bacteriol (2010) 1.02

Whole-genome sequences of Bacillus subtilis and close relatives. J Bacteriol (2012) 1.01

Assembly of the SpoIIIE DNA translocase depends on chromosome trapping in Bacillus subtilis. Curr Biol (2003) 1.00

Unique degradation signal for ClpCP in Bacillus subtilis. J Bacteriol (2003) 1.00

Reconstitution of peptidoglycan cross-linking leads to improved fluorescent probes of cell wall synthesis. J Am Chem Soc (2014) 1.00

Osmotic pressure can regulate matrix gene expression in Bacillus subtilis. Mol Microbiol (2012) 0.97

A serine sensor for multicellularity in a bacterium. Elife (2013) 0.97

Gene conservation among endospore-forming bacteria reveals additional sporulation genes in Bacillus subtilis. J Bacteriol (2012) 0.97

FtsA mutants of Bacillus subtilis impaired in sporulation. J Bacteriol (2002) 0.96

A threshold mechanism governing activation of the developmental regulatory protein sigma F in Bacillus subtilis. J Biol Chem (2004) 0.94

Genetic dissection of the sporulation protein SpoIIE and its role in asymmetric division in Bacillus subtilis. J Bacteriol (2005) 0.93

The sporulation protein SirA inhibits the binding of DnaA to the origin of replication by contacting a patch of clustered amino acids. J Bacteriol (2011) 0.93

Just-in-time control of Spo0A synthesis in Bacillus subtilis by multiple regulatory mechanisms. J Bacteriol (2011) 0.91

A second PDZ-containing serine protease contributes to activation of the sporulation transcription factor sigmaK in Bacillus subtilis. J Bacteriol (2003) 0.91

Sporulenes, heptaprenyl metabolites from Bacillus subtilis spores. Org Lett (2008) 0.89

Novel genes that influence development in Streptomyces coelicolor. J Bacteriol (2004) 0.89

Evidence in support of a docking model for the release of the transcription factor sigma F from the antisigma factor SpoIIAB in Bacillus subtilis. J Biol Chem (2003) 0.89

Unmasking novel sporulation genes in Bacillus subtilis. J Bacteriol (2004) 0.89

gerT, a newly discovered germination gene under the control of the sporulation transcription factor sigmaK in Bacillus subtilis. J Bacteriol (2007) 0.88