| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Fluorine interactions at the thrombin active site: protein backbone fragments H-C(alpha)-C=O comprise a favorable C-F environment and interactions of C-F with electrophiles.
|
Chembiochem
|
2004
|
0.99
|
|
2
|
Supramolecular patterned surfaces driven by cooperative assembly of C60 and porphyrins on metal substrates.
|
Angew Chem Int Ed Engl
|
2004
|
0.93
|
|
3
|
A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pKa and binding affinity and evidence for intermolecular C-F...CN interactions.
|
Org Biomol Chem
|
2004
|
0.93
|
|
4
|
Cation-pi interactions at the active site of factor Xa: dramatic enhancement upon stepwise N-alkylation of ammonium ions.
|
Angew Chem Int Ed Engl
|
2009
|
0.92
|
|
5
|
Crystal Structure of Potassium Croconate Dihydrate, after 175 Years.
|
Angew Chem Int Ed Engl
|
2001
|
0.92
|
|
6
|
A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions.
|
Angew Chem Int Ed Engl
|
2003
|
0.90
|
|
7
|
A fluorine scan at the catalytic center of thrombin: C--F, C--OH, and C--OMe bioisosterism and fluorine effects on pKa and log D values.
|
ChemMedChem
|
2006
|
0.84
|
|
8
|
Shape-persistent chiral alleno-acetylenic macrocycles and cyclophanes by acetylenic scaffolding with 1,3-diethynylallenes.
|
Angew Chem Int Ed Engl
|
2005
|
0.83
|
|
9
|
Two-dimensional acetylenic scaffolding: extended donor-substituted perethynylated dehydroannulenes.
|
Chem Asian J
|
2006
|
0.82
|
|
10
|
A new class of organic donor-acceptor molecules with large third-order optical nonlinearities.
|
Chem Commun (Camb)
|
2005
|
0.81
|
|
11
|
Macrocyclic ferrocenyl-bisimidazoline palladacycle dimers as highly active and enantioselective catalysts for the aza-claisen rearrangement of Z-configured N-para-methoxyphenyl trifluoroacetimidates.
|
Angew Chem Int Ed Engl
|
2007
|
0.81
|
|
12
|
Charge-transfer chromophores by cycloaddition-retro-electrocyclization: multivalent systems and cascade reactions.
|
Angew Chem Int Ed Engl
|
2007
|
0.80
|
|
13
|
A novel reaction of 7,7,8,8-tetracyanoquinodimethane (TCNQ): charge-transfer chromophores by [2 + 2] cycloaddition with alkynes.
|
Chem Commun (Camb)
|
2007
|
0.79
|
|
14
|
Synthesis of nearly enantiopure allylic amines by aza-Claisen rearrangement of Z-configured allylic trifluoroacetimidates catalyzed by highly active ferrocenylbispalladacycles.
|
Chemistry
|
2008
|
0.79
|
|
15
|
Donor-substituted cyanoethynylethenes: powerful chromophores for opto-electronic applications.
|
Org Biomol Chem
|
2003
|
0.79
|
|
16
|
1,3-Diethynylallenes (DEAs): enantioselective synthesis, absolute configuration, and chiral induction in 1,1,4,4-tetracyanobuta-1,3-dienes (TCBDs).
|
Chemistry
|
2008
|
0.79
|
|
17
|
Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors.
|
Org Biomol Chem
|
2006
|
0.78
|
|
18
|
Selective steroid recognition by a partially bridged resorcin[4]arene cavitand.
|
Chem Commun (Camb)
|
2005
|
0.78
|
|
19
|
N-arylated 3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]azepines: axially chiral donors with high helical twisting powers for nonplanar push-pull chromophores.
|
Chemistry
|
2009
|
0.78
|
|
20
|
Cyanoethynylethenes: a class of powerful electron acceptors for molecular scaffolding.
|
Angew Chem Int Ed Engl
|
2002
|
0.77
|
|
21
|
Synthesis of trans-1, trans-2, trans-3, and trans-4 bisadducts of C60 by regio- and stereoselective tether-directed remote functionalization.
|
Chemistry
|
2005
|
0.77
|
|
22
|
Organic super-acceptors with efficient intramolecular charge-transfer interactions by [2+2] cycloadditions of TCNE, TCNQ, and F4-TCNQ to donor-substituted cyanoalkynes.
|
Chemistry
|
2009
|
0.76
|
|
23
|
Donor-substituted 1,1,4,4-tetracyanobutadienes (TCBDS): new chromophores with efficient intramolecular charge-transfer interactions by atom-economic synthesis.
|
Chemistry
|
2006
|
0.76
|
|
24
|
Mapping the fluorophilicity of a hydrophobic pocket: synthesis and biological evaluation of tricyclic thrombin inhibitors directing fluorinated alkyl groups into the p pocket.
|
ChemMedChem
|
2006
|
0.76
|
|
25
|
Novel extended tetrathiafulvalenes based on acetylenic spacers: synthesis and electronic properties.
|
Chemistry
|
2002
|
0.75
|
|
26
|
Switching the regioselectivity in cycloaddition-retro-electrocyclizations between donor-activated alkynes and the electron-accepting olefins TCNE and TCNQ.
|
Chem Asian J
|
2010
|
0.75
|
|
27
|
Donor-substituted peralkynylated "radiaannulenes": novel all-carbon macrocycles with an intense intramolecular charge-transfer.
|
Chem Commun (Camb)
|
2003
|
0.75
|
|
28
|
Dendritic metalloporphyrins with a distal H-bond donor as mimics of haemoglobin.
|
Org Biomol Chem
|
2003
|
0.75
|
|
29
|
Nucleophilic trifluoromethylation of cyclic imides using (trifluoromethyl)trimethylsilane CF3SiMe3.
|
Org Biomol Chem
|
2004
|
0.75
|
|
30
|
Enantiomerically pure alleno-acetylenic macrocycles: synthesis, solid-state structures, chiroptical properties, and electron localization function analysis.
|
Chemistry
|
2010
|
0.75
|
|
31
|
Regular acyclic and macrocyclic [AB] oligomers by formation of push-pull chromophores in the chain-growth step.
|
Chemistry
|
2011
|
0.75
|