Ulrike Obst-Sander

Author PubWeight™ 10.19^‹?›

Rank	Title	Journal	Year	PubWeight™‹?›
1	Fluorine in medicinal chemistry.	Chembiochem	2004	3.25
2	Quantification of cation-pi interactions in protein-ligand complexes: crystal-structure analysis of Factor Xa bound to a quaternary ammonium ion ligand.	Angew Chem Int Ed Engl	2005	1.20
3	Fluorine interactions at the thrombin active site: protein backbone fragments H-C(alpha)-C=O comprise a favorable C-F environment and interactions of C-F with electrophiles.	Chembiochem	2004	0.99
4	A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pKa and binding affinity and evidence for intermolecular C-F...CN interactions.	Org Biomol Chem	2004	0.93
5	A fluorine scan at the catalytic center of thrombin: C--F, C--OH, and C--OMe bioisosterism and fluorine effects on pKa and log D values.	ChemMedChem	2006	0.84
6	Dose-dependent antithrombotic activity of an orally active tissue factor/factor VIIa inhibitor without concomitant enhancement of bleeding propensity.	Bioorg Med Chem	2006	0.82
7	Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors.	Bioorg Med Chem Lett	2005	0.78
8	Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors.	Org Biomol Chem	2006	0.78
9	Mapping the fluorophilicity of a hydrophobic pocket: synthesis and biological evaluation of tricyclic thrombin inhibitors directing fluorinated alkyl groups into the p pocket.	ChemMedChem	2006	0.76