Published in Chest on August 01, 2006
Spatial and temporal heterogeneity of ventilator-associated lung injury after surfactant depletion. J Appl Physiol (1985) (2008) 1.88
Redistribution of pulmonary blood flow impacts thermodilution-based extravascular lung water measurements in a model of acute lung injury. Anesthesiology (2009) 1.62
Ability of dynamic airway pressure curve profile and elastance for positive end-expiratory pressure titration. Intensive Care Med (2008) 1.11
Analysis of regional mechanics in canine lung injury using forced oscillations and 3D image registration. Ann Biomed Eng (2010) 1.04
Relation between shunt, aeration, and perfusion in experimental acute lung injury. Am J Respir Crit Care Med (2007) 1.02
Acute respiratory distress syndrome: we can't miss regional lung perfusion! BMC Anesthesiol (2015) 0.79
Targeted delivery of liquid microvolumes into the lung. Proc Natl Acad Sci U S A (2015) 0.77
Mortality after surgery in Europe: a 7 day cohort study. Lancet (2012) 9.96
Lung recruitment in patients with the acute respiratory distress syndrome. N Engl J Med (2006) 8.64
Tidal hyperinflation during low tidal volume ventilation in acute respiratory distress syndrome. Am J Respir Crit Care Med (2006) 6.22
Protective mechanical ventilation during general anesthesia for open abdominal surgery improves postoperative pulmonary function. Anesthesiology (2013) 5.04
Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: a multiple-center epidemiological study. Crit Care Med (2005) 4.61
Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis. Neuron (2012) 4.48
High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial. Lancet (2014) 4.45
Intraoperative protective mechanical ventilation for prevention of postoperative pulmonary complications: a comprehensive review of the role of tidal volume, positive end-expiratory pressure, and lung recruitment maneuvers. Anesthesiology (2015) 4.25
Evolution of mechanical ventilation in response to clinical research. Am J Respir Crit Care Med (2007) 3.45
Percutaneous dilatational tracheostomy with a double-lumen endotracheal tube: a comparison of feasibility, gas exchange, and airway pressures. Chest (2015) 3.20
Concern Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery. Eur Heart J (2009) 3.14
Prospective external validation of a predictive score for postoperative pulmonary complications. Anesthesiology (2014) 3.01
Epidemiology of sepsis in Germany: results from a national prospective multicenter study. Intensive Care Med (2007) 2.97
Evolution of mortality over time in patients receiving mechanical ventilation. Am J Respir Crit Care Med (2013) 2.95
Tidal volume lower than 6 ml/kg enhances lung protection: role of extracorporeal carbon dioxide removal. Anesthesiology (2009) 2.91
Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study. Intensive Care Med (2004) 2.56
Lung opening and closing during ventilation of acute respiratory distress syndrome. Am J Respir Crit Care Med (2009) 2.47
Effects of different levels of pressure support variability in experimental lung injury. Anesthesiology (2009) 2.38
Pressure support improves oxygenation and lung protection compared to pressure-controlled ventilation and is further improved by random variation of pressure support. Crit Care Med (2011) 2.34
Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients. Intensive Care Med (2015) 2.25
The application of esophageal pressure measurement in patients with respiratory failure. Am J Respir Crit Care Med (2014) 2.16
Characteristics and outcomes of ventilated patients according to time to liberation from mechanical ventilation. Am J Respir Crit Care Med (2011) 2.15
Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease. J Biol Chem (2010) 2.10
Meta-analysis: ventilation strategies and outcomes of the acute respiratory distress syndrome and acute lung injury. Ann Intern Med (2009) 2.07
Outcomes of patients ventilated with synchronized intermittent mandatory ventilation with pressure support: a comparative propensity score study. Chest (2009) 2.03
Effects of hypervolemia and hypertension on regional cerebral blood flow, intracranial pressure, and brain tissue oxygenation after subarachnoid hemorrhage. Crit Care Med (2007) 1.99
HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration. PLoS Biol (2013) 1.96
Incidence, risk factors and outcome of barotrauma in mechanically ventilated patients. Intensive Care Med (2004) 1.96
Comparative effects of proportional assist and variable pressure support ventilation on lung function and damage in experimental lung injury. Crit Care Med (2012) 1.83
Noisy pressure support ventilation: a pilot study on a new assisted ventilation mode in experimental lung injury. Crit Care Med (2008) 1.79
An Official ATS/ERS/ESICM/SCCM/SRLF Statement: Prevention and Management of Acute Renal Failure in the ICU Patient: an international consensus conference in intensive care medicine. Am J Respir Crit Care Med (2010) 1.77
A novel extracorporeal CO(2) removal system: results of a pilot study of hypercapnic respiratory failure in patients with COPD. Chest (2013) 1.75
Subject-ventilator synchrony during neural versus pneumatically triggered non-invasive helmet ventilation. Intensive Care Med (2008) 1.74
Proteoglycan fragmentation and respiratory mechanics in mechanically ventilated healthy rats. J Appl Physiol (1985) (2007) 1.74
Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients. J Clin Invest (2015) 1.74
Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease. J Clin Invest (2011) 1.66
Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine: European Perioperative Clinical Outcome (EPCO) definitions: a statement from the ESA-ESICM joint taskforce on perioperative outcome measures. Eur J Anaesthesiol (2015) 1.64
Detection of local lung air content by electrical impedance tomography compared with electron beam CT. J Appl Physiol (1985) (2002) 1.61
Effects of positive end-expiratory pressure on regional cerebral blood flow, intracranial pressure, and brain tissue oxygenation. Crit Care Med (2005) 1.61
Effects of partial ventilatory support modalities on respiratory function in severe hypoxemic lung injury. Crit Care Med (2006) 1.60
Bedside selection of positive end-expiratory pressure in mild, moderate, and severe acute respiratory distress syndrome. Crit Care Med (2014) 1.60
Acute effects of intracranial hypertension and ARDS on pulmonary and neuronal damage: a randomized experimental study in pigs. Intensive Care Med (2011) 1.57
Lung inhomogeneity in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med (2014) 1.55
Early and small changes in serum creatinine concentrations are associated with mortality in mechanically ventilated patients. Shock (2010) 1.54
Relationship between gas exchange response to prone position and lung recruitability during acute respiratory failure. Intensive Care Med (2009) 1.53
Clinical review: Positive end-expiratory pressure and cardiac output. Crit Care (2005) 1.51
Lung recruitability is better estimated according to the Berlin definition of acute respiratory distress syndrome at standard 5 cm H2O rather than higher positive end-expiratory pressure: a retrospective cohort study. Crit Care Med (2015) 1.51
Impact of pressure profile and duration of recruitment maneuvers on morphofunctional and biochemical variables in experimental lung injury. Crit Care Med (2011) 1.51
Methylprednisolone improves lung mechanics and reduces the inflammatory response in pulmonary but not in extrapulmonary mild acute lung injury in mice. Crit Care Med (2008) 1.49
Effect of different cycling-off criteria and positive end-expiratory pressure during pressure support ventilation in patients with chronic obstructive pulmonary disease. Crit Care Med (2007) 1.48
Higher levels of spontaneous breathing reduce lung injury in experimental moderate acute respiratory distress syndrome. Crit Care Med (2014) 1.47
Development and validation of a score to predict postoperative respiratory failure in a multicentre European cohort: A prospective, observational study. Eur J Anaesthesiol (2015) 1.47
Hemodynamics and vasopressor support during targeted temperature management at 33°C Versus 36°C after out-of-hospital cardiac arrest: a post hoc study of the target temperature management trial*. Crit Care Med (2015) 1.46
Low respiratory rate plus minimally invasive extracorporeal Co2 removal decreases systemic and pulmonary inflammatory mediators in experimental Acute Respiratory Distress Syndrome. Crit Care Med (2014) 1.44
Pleural effusion in patients with acute lung injury: a CT scan study. Crit Care Med (2013) 1.43
Suppression of protein aggregation by chaperone modification of high molecular weight complexes. Brain (2012) 1.42
Effects of intravascular volume replacement on lung and kidney function and damage in nonseptic experimental lung injury. Anesthesiology (2013) 1.42
Prevention of atelectasis in morbidly obese patients during general anesthesia and paralysis: a computerized tomography study. Anesthesiology (2009) 1.41
Intensive care medicine: a multidisciplinary approach! Eur J Anaesthesiol (2011) 1.40
The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability. Crit Care (2008) 1.34
An increase of abdominal pressure increases pulmonary edema in oleic acid-induced lung injury. Am J Respir Crit Care Med (2003) 1.33
Airway pressure-time curve profile (stress index) detects tidal recruitment/hyperinflation in experimental acute lung injury. Crit Care Med (2004) 1.33
Lung-Protective Ventilation With Low Tidal Volumes and the Occurrence of Pulmonary Complications in Patients Without Acute Respiratory Distress Syndrome: A Systematic Review and Individual Patient Data Analysis. Crit Care Med (2015) 1.31
Evidence and consensus-based German guidelines for the management of analgesia, sedation and delirium in intensive care--short version. Ger Med Sci (2010) 1.30
Variable tidal volumes improve lung protective ventilation strategies in experimental lung injury. Am J Respir Crit Care Med (2009) 1.27
SIRT2 ablation has no effect on tubulin acetylation in brain, cholesterol biosynthesis or the progression of Huntington's disease phenotypes in vivo. PLoS One (2012) 1.27
Binding properties of a locust's chemosensory protein. Biochem Biophys Res Commun (2002) 1.26
Association between tidal volume size, duration of ventilation, and sedation needs in patients without acute respiratory distress syndrome: an individual patient data meta-analysis. Intensive Care Med (2014) 1.25
How to minimise ventilator-induced lung injury in transplanted lungs: The role of protective ventilation and other strategies. Eur J Anaesthesiol (2015) 1.23
Intraoperative recruitment maneuver reverses detrimental pneumoperitoneum-induced respiratory effects in healthy weight and obese patients undergoing laparoscopy. Anesthesiology (2010) 1.22
Target Temperature Management after out-of-hospital cardiac arrest--a randomized, parallel-group, assessor-blinded clinical trial--rationale and design. Am Heart J (2012) 1.22
Regional lung perfusion as determined by electrical impedance tomography in comparison with electron beam CT imaging. IEEE Trans Med Imaging (2002) 1.21
Chemosensory proteins of Locusta migratoria. Insect Mol Biol (2003) 1.21
Assessment of cardiac preload and left ventricular function under increasing levels of positive end-expiratory pressure. Intensive Care Med (2003) 1.20
Protective versus Conventional Ventilation for Surgery: A Systematic Review and Individual Patient Data Meta-analysis. Anesthesiology (2015) 1.19
Video-assisted thoracoscopic surgery of mediastinal bronchogenic cysts in adults: a single-center experience. Ann Thorac Surg (2004) 1.17
K-RAS mutant pancreatic tumors show higher sensitivity to MEK than to PI3K inhibition in vivo. PLoS One (2012) 1.16
Resuscitation from hemorrhagic shock: experimental model comparing normal saline, dextran, and hypertonic saline solutions. Crit Care Med (2003) 1.16
Discrimination of alarm pheromone (E)-beta-farnesene by aphid odorant-binding proteins. Insect Biochem Mol Biol (2009) 1.14
Recruitment maneuver in pulmonary and extrapulmonary experimental acute lung injury. Crit Care Med (2008) 1.14
New treatment of acute hypoxemic respiratory failure: noninvasive pressure support ventilation delivered by helmet--a pilot controlled trial. Crit Care Med (2002) 1.13
TR-FRET-based duplex immunoassay reveals an inverse correlation of soluble and aggregated mutant huntingtin in huntington's disease. Chem Biol (2012) 1.13
HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation. Brain (2014) 1.13
Spontaneous breathing in mild and moderate versus severe acute respiratory distress syndrome. Curr Opin Crit Care (2014) 1.12
Ability of dynamic airway pressure curve profile and elastance for positive end-expiratory pressure titration. Intensive Care Med (2008) 1.11
Mutant huntingtin impairs immune cell migration in Huntington disease. J Clin Invest (2012) 1.11
Sleep-disordered breathing and postoperative outcomes: patient safety first! Chest (2013) 1.11
Two odorant-binding proteins mediate the behavioural response of aphids to the alarm pheromone (E)-ß-farnesene and structural analogues. PLoS One (2012) 1.10