Published in Proc Am Thorac Soc on August 01, 2006
miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis. J Exp Med (2010) 4.71
Participation of miR-200 in pulmonary fibrosis. Am J Pathol (2011) 1.43
Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease. Proc Am Thorac Soc (2009) 1.38
Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in mice. J Clin Invest (2011) 1.17
miR-145 regulates myofibroblast differentiation and lung fibrosis. FASEB J (2013) 1.15
Retracted miR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis. FASEB J (2012) 0.99
Fasudil, a Rho-kinase inhibitor, attenuates bleomycin-induced pulmonary fibrosis in mice. Int J Mol Sci (2012) 0.98
The antifibrotic effects and mechanisms of microRNA-26a action in idiopathic pulmonary fibrosis. Mol Ther (2014) 0.92
The Anti-fibrotic Effects and Mechanisms of MicroRNA-486-5p in Pulmonary Fibrosis. Sci Rep (2015) 0.86
MicroRNA-29 mediates TGFβ1-induced extracellular matrix synthesis by targeting wnt/β-catenin pathway in human orbital fibroblasts. Int J Clin Exp Pathol (2014) 0.85
Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-γ. Exp Mol Med (2011) 0.84
Combined pulmonary fibrosis and emphysema: an increasingly recognized condition. J Bras Pneumol (2014) 0.83
Combined Pulmonary Fibrosis and Emphysema Syndrome: A New Phenotype within the Spectrum of Smoking-Related Interstitial Lung Disease. Pulm Med (2012) 0.83
Dihydroartemisinin supresses inflammation and fibrosis in bleomycine-induced pulmonary fibrosis in rats. Int J Clin Exp Pathol (2015) 0.81
The role of miR-497-5p in myofibroblast differentiation of LR-MSCs and pulmonary fibrogenesis. Sci Rep (2017) 0.75
Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat Med (2005) 8.49
Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science (2004) 6.28
A chitinase-like protein in the lung and circulation of patients with severe asthma. N Engl J Med (2007) 6.02
Asthma: mechanisms of disease persistence and progression. Annu Rev Immunol (2004) 4.72
Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med (2002) 4.65
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. N Engl J Med (2008) 4.58
Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nat Med (2004) 3.64
Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury. Annu Rev Physiol (2011) 3.25
Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. J Exp Med (2004) 2.84
New insights into the pathogenesis of asthma. J Clin Invest (2003) 2.66
Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med (2006) 2.63
Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med (2009) 2.61
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling. J Clin Invest (2002) 2.52
Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice. J Clin Invest (2008) 2.24
Role of tissue protection in lethal respiratory viral-bacterial coinfection. Science (2013) 2.22
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proc Natl Acad Sci U S A (2009) 2.16
Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions. J Allergy Clin Immunol (2003) 2.05
Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle. Diabetes (2009) 2.00
TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol (2008) 1.97
Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol (2002) 1.95
Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. J Clin Invest (2003) 1.90
Apoptosis and emphysema: the missing link. Am J Respir Cell Mol Biol (2003) 1.82
IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol (2002) 1.81
TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P. Int J Biochem Cell Biol (2010) 1.79
Chitin regulation of immune responses: an old molecule with new roles. Curr Opin Immunol (2008) 1.75
Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis. J Exp Med (2007) 1.67
Conditional overexpression of bioactive transforming growth factor-beta1 in neonatal mouse lung: a new model for bronchopulmonary dysplasia? Am J Respir Cell Mol Biol (2004) 1.67
Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling. Semin Cell Dev Biol (2002) 1.62
Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury. J Clin Invest (2005) 1.61
Thyroid transcription factor 1 is an independent prognostic factor for patients with stage I lung adenocarcinoma. J Clin Oncol (2008) 1.61
Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9. Am J Respir Cell Mol Biol (2002) 1.55
Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways. J Biol Chem (2002) 1.54
Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema. J Immunol (2005) 1.53
A novel pathway that regulates inflammatory disease in the respiratory tract. J Immunol (2007) 1.51
Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12. J Biol Chem (2007) 1.50
Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma. J Allergy Clin Immunol (2005) 1.49
RIG-like helicase innate immunity inhibits vascular endothelial growth factor tissue responses via a type I IFN-dependent mechanism. Am J Respir Crit Care Med (2011) 1.49
Chitin is a size-dependent regulator of macrophage TNF and IL-10 production. J Immunol (2009) 1.49
Elevated serum angiopoietin 2 levels are associated with increased mortality in sepsis. Shock (2009) 1.47
Cytokines in tolerance to hyperoxia-induced injury in the developing and adult lung. Free Radic Biol Med (2006) 1.45
Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation. Am J Physiol Lung Cell Mol Physiol (2006) 1.44
Regulated angiogenesis and vascular regression in mice overexpressing vascular endothelial growth factor in airways. Am J Pathol (2004) 1.39
Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations. Am J Physiol Lung Cell Mol Physiol (2005) 1.39
The C10/CCL6 chemokine and CCR1 play critical roles in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol (2004) 1.37
Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema. J Clin Invest (2005) 1.37
Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling. J Biol Chem (2006) 1.35
IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation. J Immunol (2007) 1.34
Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung. Proc Natl Acad Sci U S A (2006) 1.32
ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo. J Clin Invest (2005) 1.31
The chitinase-like proteins breast regression protein-39 and YKL-40 regulate hyperoxia-induced acute lung injury. Am J Respir Crit Care Med (2010) 1.31
Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling. Proc Am Thorac Soc (2006) 1.31
Idiopathic pulmonary fibrosis: new insights into pathogenesis. Clin Chest Med (2004) 1.31
Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro. J Allergy Clin Immunol (2003) 1.27
Activation of the STAT pathway in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2004) 1.25
Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2. Cell Rep (2013) 1.24
Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung antibacterial responses. Cell Host Microbe (2012) 1.23
Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol (2007) 1.23
Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. J Clin Invest (2006) 1.22
Neuropilin-1 regulates vascular endothelial growth factor-mediated endothelial permeability. Circ Res (2005) 1.21
Modern concepts on the role of inflammation in pulmonary fibrosis. Arch Pathol Lab Med (2011) 1.21
Airway remodeling in asthma: therapeutic implications of mechanisms. Physiology (Bethesda) (2005) 1.19
Genetic variation in the promoter region of chitinase 3-like 1 is associated with atopy. Am J Respir Crit Care Med (2008) 1.19
IL-18 induces emphysema and airway and vascular remodeling via IFN-γ, IL-17A, and IL-13. Am J Respir Crit Care Med (2012) 1.18
Interleukin-11 and interleukin-6 protect cultured human endothelial cells from H2O2-induced cell death. Am J Respir Cell Mol Biol (2003) 1.17
Back to the future: historical perspective on the pathogenesis of idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol (2005) 1.16
Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema. Am J Respir Cell Mol Biol (2010) 1.15
Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response. J Clin Invest (2005) 1.15
VEGF-induced heme oxygenase-1 confers cytoprotection from lethal hyperoxia in vivo. FASEB J (2007) 1.14
Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury. Am J Respir Crit Care Med (2005) 1.14
Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of early growth response-1 and platelet-derived growth factor ligands in pulmonary fibroblasts. J Immunol (2006) 1.11
Airway epithelial STAT3 is required for allergic inflammation in a murine model of asthma. J Immunol (2007) 1.10
Developmental regulation of NO-mediated VEGF-induced effects in the lung. Am J Respir Cell Mol Biol (2008) 1.10
Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis. Am J Respir Crit Care Med (2012) 1.09