Published in FASEB J on September 01, 2006
Mechanisms of cellular uptake of cell-penetrating peptides. J Biophys (2011) 2.34
Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides. Nucleic Acids Res (2008) 2.06
Exosomal transfer of proteins and RNAs at synapses in the nervous system. Biol Direct (2007) 1.93
The design of guanidinium-rich transporters and their internalization mechanisms. Adv Drug Deliv Rev (2007) 1.91
Macropinocytosis: searching for an endocytic identity and role in the uptake of cell penetrating peptides. J Cell Mol Med (2007) 1.65
Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34+ leukaemia cells. Biochem J (2007) 1.44
Cell entry of arginine-rich peptides is independent of endocytosis. J Biol Chem (2008) 1.41
Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides. Bioconjug Chem (2011) 1.32
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides. Nat Commun (2011) 1.30
Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs). Mol Endocrinol (2009) 1.25
Cargo-dependent cytotoxicity and delivery efficacy of cell-penetrating peptides: a comparative study. Biochem J (2007) 1.20
Nuclear and cytosolic JNK signalling in neurons. Nat Rev Neurosci (2014) 1.17
Antimicrobial peptides with cell-penetrating peptide properties and vice versa. Eur Biophys J (2011) 1.12
Fundamental molecular mechanism for the cellular uptake of guanidinium-rich molecules. J Am Chem Soc (2014) 1.08
Targeting antibodies to the cytoplasm. MAbs (2011) 1.06
Visualization and targeted disruption of protein interactions in living cells. Nat Commun (2013) 1.05
Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability. J Biol Chem (2012) 1.05
Cell-penetrating HIV1 TAT peptides can generate pores in model membranes. Biophys J (2010) 0.99
Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. Int J Cancer (2010) 0.98
Organelle targeting: third level of drug targeting. Drug Des Devel Ther (2013) 0.97
Cell-free production of transducible transcription factors for nuclear reprogramming. Biotechnol Bioeng (2009) 0.96
The chemistry and biology of oligonucleotide conjugates. Acc Chem Res (2012) 0.95
Delivery of macromolecules into live cells by simple co-incubation with a peptide. Chembiochem (2010) 0.95
Nucleolar marker for living cells. Histochem Cell Biol (2007) 0.94
A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency. J Biol Chem (2009) 0.92
Cell-penetrating peptides: achievements and challenges in application for cancer treatment. J Biomed Mater Res A (2013) 0.90
Anti HIV-1 virucidal activity of polyamide nucleic acid-membrane transducing peptide conjugates targeted to primer binding site of HIV-1 genome. Virology (2007) 0.89
Mechanism Matters: A Taxonomy of Cell Penetrating Peptides. Trends Biochem Sci (2015) 0.89
Endocytosis and membrane potential are required for HeLa cell uptake of R.I.-CKTat9, a retro-inverso Tat cell penetrating peptide. Mol Pharm (2009) 0.88
Applications of cell-penetrating peptides for tumor targeting and future cancer therapies. Pharmaceuticals (Basel) (2012) 0.87
Calcium condensation of DNA complexed with cell-penetrating peptides offers efficient, noncytotoxic gene delivery. J Pharm Sci (2010) 0.87
TAT-mediated intracellular protein delivery to primary brain cells is dependent on glycosaminoglycan expression. Biotechnol Bioeng (2009) 0.86
Slit diaphragm protein Neph1 and its signaling: a novel therapeutic target for protection of podocytes against glomerular injury. J Biol Chem (2014) 0.83
TAT and HA2 facilitate cellular uptake of gold nanoparticles but do not lead to cytosolic localisation. PLoS One (2015) 0.83
Modulation of muscle contraction by a cell-permeable peptide. J Mol Med (Berl) (2007) 0.83
Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells. Nat Chem (2017) 0.82
Determination of penetratin secondary structure in live cells with Raman microscopy. J Am Chem Soc (2010) 0.82
Intracellular Delivery of Proteins with Cell-Penetrating Peptides for Therapeutic Uses in Human Disease. Int J Mol Sci (2016) 0.81
A novel cell permeable DNA replication and repair marker. Nucleus (2014) 0.81
Cell-penetrating peptides split into two groups based on modulation of intracellular calcium concentration. J Biol Chem (2012) 0.81
Transcription factor-based modulation of neural stem cell differentiation using direct protein transduction. Cell Mol Life Sci (2010) 0.81
Intracellular delivery of nanoparticles and DNAs by IR9 cell-penetrating peptides. PLoS One (2013) 0.81
The discovery of Hsp70 domain with cell-penetrating activity. Cell Stress Chaperones (2014) 0.79
Cytoplasmic delivery and selective, multicomponent labeling with oligoarginine-linked protein tags. Bioconjug Chem (2015) 0.79
Tailored delivery of analgesic ziconotide across a blood brain barrier model using viral nanocontainers. Sci Rep (2015) 0.78
Mapping the Interaction of B Cell Leukemia 3 (BCL-3) and Nuclear Factor κB (NF-κB) p50 Identifies a BCL-3-mimetic Anti-inflammatory Peptide. J Biol Chem (2015) 0.78
Efficient entry of cell-penetrating peptide nona-arginine into adherent cells involves a transient increase in intracellular calcium. Biochem J (2015) 0.78
Toward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis. Tetrahedron (2013) 0.78
Co-operative membrane disruption between cell-penetrating peptide and cargo: implications for the therapeutic use of the Bcl-2 converter peptide D-NuBCP-9-r8. Mol Ther (2011) 0.77
Selective enhancement of the uptake and bioactivity of a TAT-conjugated peptide inhibitor of glycogen synthase kinase-3. Mol Ther (2008) 0.77
Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein Cargos. Int J Mol Sci (2016) 0.77
A general strategy for developing cell-permeable photo-modulatable organic fluorescent probes for live-cell super-resolution imaging. Nat Commun (2014) 0.77
HIV-1 Tat membrane interactions probed using X-ray and neutron scattering, CD spectroscopy and MD simulations. Biochim Biophys Acta (2014) 0.77
Functional characterisation of the WW minimal domain for delivering therapeutic proteins by adenovirus dodecahedron. PLoS One (2012) 0.76
Intracellular targeting with engineered proteins. F1000Res (2016) 0.76
Tat-Mediated Peptide Intervention in Analgesia and Anesthesia. Drug Dev Res (2010) 0.76
Interference with RUNX1/ETO leukemogenic function by cell-penetrating peptides targeting the NHR2 oligomerization domain. Biomed Res Int (2013) 0.76
Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles. Aging (Albany NY) (2016) 0.76
Cell-penetrating peptides: Possible transduction mechanisms and therapeutic applications. Biomed Rep (2016) 0.76
Principles of protein targeting to the nucleolus. Nucleus (2015) 0.76
Drug Delivery via Cell Membrane Fusion Using Lipopeptide Modified Liposomes. ACS Cent Sci (2016) 0.76
CPP-Assisted Intracellular Drug Delivery, What Is Next? Int J Mol Sci (2016) 0.75
C3 transferase gene therapy for continuous conditional RhoA inhibition. Neuroscience (2016) 0.75
Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes. Sci Rep (2017) 0.75
Investigating Engineered Ribonucleoprotein Particles to Improve Oral RNAi Delivery in Crop Insect Pests. Front Physiol (2017) 0.75
Cell-penetrating peptides as tools to enhance non-injectable delivery of biopharmaceuticals. Tissue Barriers (2016) 0.75
A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells. PLoS One (2014) 0.75
Progress in Research and Application of HIV-1 TAT-Derived Cell-Penetrating Peptide. J Membr Biol (2016) 0.75
TAT-mediated transduction of bacterial redox proteins generates a cytoprotective effect on neuronal cells. PLoS One (2017) 0.75
A critical assessment of the synthesis and biological activity of p53/Hdm2 stapled peptide inhibitors. Br J Pharmacol (2017) 0.75
Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy. Science (2008) 6.47
A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins. Mol Cell Proteomics (2007) 4.28
mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol (2004) 3.72
Direct conversion of fibroblasts into stably expandable neural stem cells. Cell Stem Cell (2012) 3.52
Targeting and tracing antigens in live cells with fluorescent nanobodies. Nat Methods (2006) 3.12
Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes. Proc Natl Acad Sci U S A (2002) 3.01
DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters. Mol Cell (2002) 2.71
Recruitment of DNA methyltransferase I to DNA repair sites. Proc Natl Acad Sci U S A (2005) 2.50
Trapped in action: direct visualization of DNA methyltransferase activity in living cells. Nat Methods (2005) 2.26
Modulation of protein properties in living cells using nanobodies. Nat Struct Mol Biol (2009) 2.15
Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation. Nucleic Acids Res (2007) 2.04
Replication-independent chromatin loading of Dnmt1 during G2 and M phases. EMBO Rep (2004) 1.98
Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice. Dis Model Mech (2009) 1.97
Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation. J Cell Biol (2005) 1.91
Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain. PLoS One (2011) 1.88
DNA labeling in living cells. Cytometry A (2005) 1.85
PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins. Nucleic Acids Res (2005) 1.71
Novel reporter mouse reveals constitutive and inflammatory expression of IFN-beta in vivo. J Immunol (2009) 1.69
Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo. Stem Cells (2010) 1.57
Stable chromosomal units determine the spatial and temporal organization of DNA replication. J Cell Sci (2004) 1.53
Differential recruitment of DNA Ligase I and III to DNA repair sites. Nucleic Acids Res (2006) 1.47
Cell entry of arginine-rich peptides is independent of endocytosis. J Biol Chem (2008) 1.41
Dynamic targeting of the replication machinery to sites of DNA damage. J Cell Biol (2004) 1.35
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides. Nat Commun (2011) 1.30
MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation. Nucleic Acids Res (2007) 1.29
Probing intranuclear environments at the single-molecule level. Biophys J (2007) 1.28
Sox2 is essential for formation of trophectoderm in the preimplantation embryo. PLoS One (2010) 1.26
Live-cell analysis of cell penetration ability and toxicity of oligo-arginines. J Pept Sci (2008) 1.25
Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase. Nat Methods (2006) 1.25
The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication. J Cell Biol (2008) 1.24
Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver. Blood (2008) 1.21
Peroxisome proliferator-activated receptor gamma control of dendritic cell function contributes to development of CD4+ T cell anergy. J Immunol (2007) 1.18
Cell cycle markers for live cell analyses. Cell Cycle (2005) 1.18
Inhibition of NF-kappaB by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis. Blood (2003) 1.17
A fluorescent two-hybrid assay for direct visualization of protein interactions in living cells. Mol Cell Proteomics (2008) 1.15
Enhanced purification of cell-permeant Cre and germline transmission after transduction into mouse embryonic stem cells. Genesis (2007) 1.13
Generation of transducible versions of transcription factors Oct4 and Sox2. Biol Chem (2008) 1.08
Fundamental molecular mechanism for the cellular uptake of guanidinium-rich molecules. J Am Chem Soc (2014) 1.08
Visualization and targeted disruption of protein interactions in living cells. Nat Commun (2013) 1.05
MeCP2 Rett mutations affect large scale chromatin organization. Hum Mol Genet (2011) 1.05
Organization of DNA replication. Cold Spring Harb Perspect Biol (2010) 1.04
Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules. PLoS One (2008) 1.03
RB reversibly inhibits DNA replication via two temporally distinct mechanisms. Mol Cell Biol (2004) 1.01
Histone acetylation controls the inactive X chromosome replication dynamics. Nat Commun (2011) 1.00
Replication of centromeric heterochromatin in mouse fibroblasts takes place in early, middle, and late S phase. Histochem Cell Biol (2005) 0.99
Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin. Nucleic Acids Res (2011) 0.99
Defining maximum levels of higher alcohols in alcoholic beverages and surrogate alcohol products. Regul Toxicol Pharmacol (2008) 0.98
A thermoresponsive and chemically defined hydrogel for long-term culture of human embryonic stem cells. Nat Commun (2013) 0.98
Cell-penetrating HIV1 TAT peptides float on model lipid bilayers. Biochemistry (2009) 0.97
Increased antigen cross-presentation but impaired cross-priming after activation of peroxisome proliferator-activated receptor gamma is mediated by up-regulation of B7H1. J Immunol (2009) 0.97
Generation and characterization of a rat monoclonal antibody specific for multiple red fluorescent proteins. Hybridoma (Larchmt) (2008) 0.96
Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites. J Cell Biol (2008) 0.96
Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen. J Cell Sci (2006) 0.95
Peroxisome proliferator-activated receptor (PPAR)gamma can inhibit chronic renal allograft damage. Am J Pathol (2010) 0.95
Nucleolar marker for living cells. Histochem Cell Biol (2007) 0.94
Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex. PLoS One (2012) 0.93
Uncoupling the replication machinery: replication fork progression in the absence of processive DNA synthesis. Cell Cycle (2008) 0.91
Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming. BMC Dev Biol (2005) 0.91
Exploring refined conditions for reprogramming cells by recombinant Oct4 protein. Int J Dev Biol (2010) 0.91
Chromatin condensation modulates access and binding of nuclear proteins. FASEB J (2009) 0.90
Multicellular self-assembled spheroidal model of the blood brain barrier. Sci Rep (2013) 0.90
Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization. Nucleic Acids Res (2012) 0.89
The SLC6A4 VNTR genotype determines transcription factor binding and epigenetic variation of this gene in response to cocaine in vitro. Addict Biol (2011) 0.88
Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies. PLoS One (2011) 0.88
Equine arteritis virus is delivered to an acidic compartment of host cells via clathrin-dependent endocytosis. Virology (2008) 0.86
CPT1alpha over-expression increases long-chain fatty acid oxidation and reduces cell viability with incremental palmitic acid concentration in 293T cells. Biochem Biophys Res Commun (2005) 0.86
Engineering cell-permeable protein. J Vis Exp (2009) 0.86
Generation and characterization of a rat monoclonal antibody specific for PCNA. Hybridoma (Larchmt) (2008) 0.85
Covalent attachment of cyclic TAT peptides to GFP results in protein delivery into live cells with immediate bioavailability. Angew Chem Int Ed Engl (2014) 0.85
Cellular reprogramming employing recombinant sox2 protein. Stem Cells Int (2012) 0.84
MicroRNAs are indispensable for reprogramming mouse embryonic fibroblasts into induced stem cell-like cells. PLoS One (2012) 0.84
Rat hd mutation reveals an essential role of centrobin in spermatid head shaping and assembly of the head-tail coupling apparatus. Biol Reprod (2009) 0.84
3D-Image analysis platform monitoring relocation of pluripotency genes during reprogramming. Nucleic Acids Res (2011) 0.83
Modulation of muscle contraction by a cell-permeable peptide. J Mol Med (Berl) (2007) 0.83
A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle. Open Biol (2014) 0.82
Structure, function and dynamics of nuclear subcompartments. Curr Opin Cell Biol (2012) 0.82
MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line. PLoS One (2012) 0.82
Heterochromatin and gene positioning: inside, outside, any side? Chromosoma (2012) 0.82
Automated selection and harvesting of pluripotent stem cell colonies. Biotechnol Appl Biochem (2013) 0.82
A novel cell permeable DNA replication and repair marker. Nucleus (2014) 0.81
A novel approach to induce cell cycle reentry in terminally differentiated muscle cells. FASEB J (2001) 0.81
Non-genetic modulation of Notch activity by artificial delivery of Notch intracellular domain into neural stem cells. Stem Cell Rev (2012) 0.81
Transcription factor-based modulation of neural stem cell differentiation using direct protein transduction. Cell Mol Life Sci (2010) 0.81
Stage-specific conditional mutagenesis in mouse embryonic stem cell-derived neural cells and postmitotic neurons by direct delivery of biologically active Cre recombinase. Stem Cells (2006) 0.81
Direct homo- and hetero-interactions of MeCP2 and MBD2. PLoS One (2013) 0.81
Stem cell engineering using transducible Cre recombinase. Methods Mol Med (2007) 0.80
Processing of lagging-strand intermediates in vitro by herpes simplex virus type 1 DNA polymerase. J Virol (2010) 0.80
Merging fields: stem cells in neurogenesis, transplantation, and disease modeling. Brain Pathol (2006) 0.80
Distribution of DNA replication proteins in Drosophila cells. BMC Cell Biol (2007) 0.80
Spatiotemporal dynamics of regulatory protein recruitment at DNA damage sites. J Cell Biochem (2008) 0.80
Live-cell targeting of his-tagged proteins by multivalent N-nitrilotriacetic acid carrier complexes. J Am Chem Soc (2014) 0.80
Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling. Stem Cell Rev (2015) 0.79