PubRank

U Hübscher

Author PubWeight™ 159.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Cell 1995 9.53
2 A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage. Mol Cell Biol 2000 2.62
3 Detection of the catalytic activities of DNA polymerases and their associated exonucleases following SDS-polyacrylamide gel electrophoresis. Nucleic Acids Res 1981 2.56
4 Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK. Genes Dev 2000 2.29
5 Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen. EMBO J 1998 2.20
6 Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. J Biol Chem 1991 2.08
7 Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA. Biochemistry 1995 2.04
8 The delta subunit of Escherichia coli DNA polymerase III holoenzyme is the dnaX gene product. Proc Natl Acad Sci U S A 1979 1.92
9 A mammalian protein complex that repairs double-strand breaks and deletions by recombination. J Biol Chem 1993 1.85
10 Efficient production of chicken egg yolk antibodies against a conserved mammalian protein. FASEB J 1990 1.79
11 Proliferating cell nuclear antigen: more than a clamp for DNA polymerases. Bioessays 1997 1.75
12 Double-check probing of DNA bending and unwinding by XPA-RPA: an architectural function in DNA repair. EMBO J 2001 1.74
13 Revised nomenclature for eukaryotic DNA polymerases. Eur J Biochem 1990 1.73
14 Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300. Mol Cell 2001 1.70
15 DNA polymerase delta, an essential enzyme for DNA transactions. Biol Chem 1997 1.65
16 Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1. Proc Natl Acad Sci U S A 2001 1.61
17 Clamping down on clamps and clamp loaders--the eukaryotic replication factor C. Eur J Biochem 1998 1.59
18 Functional roles of DNA polymerases beta and gamma. Proc Natl Acad Sci U S A 1979 1.59
19 DNA unwinding activity of replication protein A. FEBS Lett 1992 1.55
20 Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns. Proc Natl Acad Sci U S A 1995 1.53
21 Novel histone H2A-like protein of escherichia coli. Proc Natl Acad Sci U S A 1980 1.47
22 Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon. J Biol Chem 1999 1.47
23 Mammalian DNA polymerase auxiliary proteins: analysis of replication factor C-catalyzed proliferating cell nuclear antigen loading onto circular double-stranded DNA. Mol Cell Biol 1995 1.44
24 The dnaZ protein, the gamma subunit of DNA polymerase III holoenzyme of Escherichia coli. J Biol Chem 1980 1.43
25 Calf thymus RF-C as an essential component for DNA polymerase delta and epsilon holoenzymes function. Nucleic Acids Res 1992 1.43
26 Mammalian base excision repair by DNA polymerases delta and epsilon. Oncogene 1998 1.42
27 Variation of DNA polymerases-alpha, -beta. and -gamma during perinatal tissue growth and differentiation. Nucleic Acids Res 1977 1.42
28 Mechanism of inhibition of proliferating cell nuclear antigen-dependent DNA synthesis by the cyclin-dependent kinase inhibitor p21. Biochemistry 1995 1.35
29 DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene. Proc Natl Acad Sci U S A 1995 1.33
30 Tyrosine 114 is essential for the trimeric structure and the functional activities of human proliferating cell nuclear antigen. EMBO J 1995 1.31
31 Lagging strand DNA synthesis by calf thymus DNA polymerases alpha, beta, delta and epsilon in the presence of auxiliary proteins. Nucleic Acids Res 1993 1.30
32 Evidence that a high molecular weight replicative DNA polymerase is conserved during evolution. Proc Natl Acad Sci U S A 1981 1.30
33 Recovery of functional proteins in sodium dodecyl sulfate gels. Methods Enzymol 1983 1.30
34 Mammalian DNA polymerase alpha holoenzymes with possible functions at the leading and lagging strand of the replication fork. Proc Natl Acad Sci U S A 1984 1.29
35 Identity of DNA polymerase gamma from synaptosomal mitochondria and rat-brain nuclei. Eur J Biochem 1977 1.24
36 Activity profiles of enzymes that control the uracil incorporation into DNA during neuronal development. Mutat Res 1990 1.23
37 Calf thymus DNA polymerase delta: purification, biochemical and functional properties of the enzyme after its separation from DNA polymerase alpha, a DNA dependent ATPase and proliferating cell nuclear antigen. Nucleic Acids Res 1988 1.20
38 Functions of DNA polymerases alpha, beta, and gamma in neurons during development. Cold Spring Harb Symp Quant Biol 1979 1.20
39 Eukaryotic DNA replication. Enzymes and proteins acting at the fork. Eur J Biochem 1990 1.20
40 In eukaryotic flap endonuclease 1, the C terminus is essential for substrate binding. J Biol Chem 2000 1.18
41 HIV-1 reverse transcriptase and integrase enzymes physically interact and inhibit each other. FEBS Lett 2001 1.17
42 DNA polymerases in prokaryotes and eukaryotes: mode of action and biological implications. Experientia 1983 1.16
43 Strand displacement activity of the human immunodeficiency virus type 1 reverse transcriptase heterodimer and its individual subunits. J Biol Chem 1994 1.15
44 Structural homology among calf thymus alpha-polymerase polypeptides. Nucleic Acids Res 1982 1.14
45 A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells. EMBO J 1996 1.14
46 Mediation of proliferating cell nuclear antigen (PCNA)-dependent DNA replication through a conserved p21(Cip1)-like PCNA-binding motif present in the third subunit of human DNA polymerase delta. J Biol Chem 2001 1.14
47 The large subunit of HIV-1 reverse transcriptase interacts with beta-actin. Nucleic Acids Res 1995 1.13
48 Mammalian DNA helicase. Nucleic Acids Res 1985 1.12
49 The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scattering. J Mol Biol 1998 1.12
50 A direct interaction between proliferating cell nuclear antigen (PCNA) and Cdk2 targets PCNA-interacting proteins for phosphorylation. J Biol Chem 2000 1.11
51 Differential discrimination of DNA polymerase for variants of the non-standard nucleobase pair between xanthosine and 2,4-diaminopyrimidine, two components of an expanded genetic alphabet. Nucleic Acids Res 1996 1.11
52 Eukaryotic DNA helicases: essential enzymes for DNA transactions. Chromosoma 1992 1.11
53 Four different DNA helicases from calf thymus. J Biol Chem 1992 1.10
54 DNA unwinding by replication protein A is a property of the 70 kDa subunit and is facilitated by phosphorylation of the 32 kDa subunit. Nucleic Acids Res 1993 1.10
55 DNA helicase from calf thymus. Purification to apparent homogeneity and biochemical characterization of the enzyme. J Biol Chem 1990 1.09
56 Replication factor C interacts with the C-terminal side of proliferating cell nuclear antigen. J Biol Chem 1997 1.08
57 DNA polymerase switching: I. Replication factor C displaces DNA polymerase alpha prior to PCNA loading. J Mol Biol 2000 1.07
58 Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions. J Mol Biol 1997 1.07
59 Humoral immune reactivity to feline leukemia virus and associated antigens in cats naturally infected with feline leukemia virus. Cancer Res 1980 1.06
60 DNA polymerase delta holoenzyme: action on single-stranded DNA and on double-stranded DNA in the presence of replicative DNA helicases. Biochemistry 1995 1.06
61 DNA polymerase beta from brain neurons is a repair enzyme. Eur J Biochem 1979 1.06
62 Resistance of human nucleotide excision repair synthesis in vitro to p21Cdn1. Oncogene 1998 1.06
63 Glyceraldehyde-3-phosphate dehydrogenase is a nonhistone protein and a possible activator of transcription in neurons. J Neurochem 1986 1.03
64 Calf thymus DNA polymerase delta independent of proliferating cell nuclear antigen (PCNA). Nucleic Acids Res 1989 1.03
65 Specificity assessment of feline T-lymphotropic lentivirus serology. Zentralbl Veterinarmed B 1988 1.03
66 Origin of adeno-associated virus DNA replication is a target of carcinogen-inducible DNA amplification. J Virol 1991 1.03
67 DNA replication machinery: functional characterization of a complex containing DNA polymerase alpha, DNA polymerase delta, and replication factor C suggests an asymmetric DNA polymerase dimer. Biochemistry 1996 1.03
68 Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins. Nucleic Acids Res 2002 1.03
69 Sites of termination of in vitro DNA synthesis on cis-diamminedichloroplatinum(II) treated single-stranded DNA: a comparison between E. coli DNA polymerase I and eucaryotic DNA polymerases alpha. Nucleic Acids Res 1988 1.02
70 Do DNA polymerases delta and alpha act coordinately as leading and lagging strand replicases? FEBS Lett 1988 1.01
71 A mammalian DNA polymerase alpha holoenzyme functioning on defined in vivo-like templates. EMBO J 1982 1.00
72 DNA polymerase switching: II. Replication factor C abrogates primer synthesis by DNA polymerase alpha at a critical length. J Mol Biol 2000 0.99
73 Mammalian DNA polymerase alpha: a replication competent holoenzyme form from calf thymus. Nucleic Acids Res 1987 0.98
74 Assembly of DNA polymerase delta and epsilon holoenzymes depends on the geometry of the DNA template. Nucleic Acids Res 1994 0.96
75 Production of active mouse DNA polymerase delta in bacteria. Gene 1995 0.96
76 Inhibitor analysis of calf thymus DNA polymerases alpha, delta and epsilon. FEBS Lett 1994 0.95
77 A coordinated interplay: proteins with multiple functions in DNA replication, DNA repair, cell cycle/checkpoint control, and transcription. Prog Nucleic Acid Res Mol Biol 2001 0.95
78 DNA polymerase epsilon interacts with proliferating cell nuclear antigen in primer recognition and elongation. Biochemistry 1995 0.95
79 The p15 carboxyl-terminal proteolysis product of the human immunodeficiency virus type 1 reverse transcriptase p66 has DNA polymerase activity. Proc Natl Acad Sci U S A 1991 0.94
80 Eukaryotic DNA helicases. FEBS Lett 1990 0.93
81 DNA fingerprinting: improved DNA extraction from small blood samples. Nucleic Acids Res 1988 0.93
82 Effects of beta-lactam antibiotics on proliferating eucaryotic cells. Antimicrob Agents Chemother 1987 0.92
83 Chromatin changes accompanying neuronal differentiation. Cold Spring Harb Symp Quant Biol 1983 0.92
84 Modulation of cellular response to cisplatin by a novel inhibitor of DNA polymerase beta. Mol Pharmacol 2005 0.91
85 Double replica southwestern. Nucleic Acids Res 1987 0.90
86 Cloning of a mouse cDNA encoding DNA polymerase delta: refinement of the homology boxes. Gene 1993 0.90
87 Chimeric HIV-1 and feline immunodeficiency virus reverse transcriptases: critical role of the p51 subunit in the structural integrity of heterodimeric lentiviral DNA polymerases. J Mol Biol 1998 0.90
88 A novel interaction of tRNA(Lys,3) with the feline immunodeficiency virus RNA genome governs initiation of minus strand DNA synthesis. J Biol Chem 2001 0.90
89 Enzyme studies of phi X174 DNA replication. Prog Nucleic Acid Res Mol Biol 1981 0.90
90 Calf thymus DNA helicase F, a replication protein A copurifying enzyme. Nucleic Acids Res 1994 0.89
91 Calf thymus Hsc70 protein protects and reactivates prokaryotic and eukaryotic enzymes. J Biol Chem 1995 0.89
92 A unified nomenclature for the subunits of eukaryotic DNA polymerase delta. Trends Biochem Sci 2001 0.89
93 Germ line transformation of mammals by pronuclear microinjection. Exp Physiol 2000 0.88
94 A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperatures. Eur J Biochem 2000 0.88
95 Dual mode of interaction of DNA polymerase epsilon with proliferating cell nuclear antigen in primer binding and DNA synthesis. J Mol Biol 1999 0.88
96 DNA polymerase delta and epsilon holoenzymes from calf thymus. Chromosoma 1992 0.87
97 Regulation of DNA metabolic enzymes upon induction of preB cell development and V(D)J recombination: up-regulation of DNA polymerase delta. Nucleic Acids Res 1997 0.87
98 Human Immunodeficiency Virus type 1 reverse transcriptase. Biol Chem Hoppe Seyler 1996 0.87
99 DNA ligase I selectively affects DNA synthesis by DNA polymerases delta and epsilon suggesting differential functions in DNA replication and repair. J Biol Chem 1998 0.86
100 Developmental activity profile of DNA polymerases delta and alpha in rat neurons suggests a coordinated in vivo function. In Vivo 1992 0.86
101 Effects of hyperoxia on DNA synthesis in cultured porcine aortic endothelial cells. J Appl Physiol (1985) 1985 0.86
102 Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase. J Med Chem 1998 0.85
103 DNA synthesis enzymes and proliferating cell nuclear antigen in normal and neoplastic nerve cells. Anticancer Res 1992 0.84
104 Feline immunodeficiency virus reverse transcriptase: expression, functional characterization, and reconstitution of the 66- and 51-kilodalton subunits. J Virol 1995 0.84
105 DNA methyltransferases: activity minigel analysis and determination with DNA covalently bound to a solid matrix. Anal Biochem 1985 0.84
106 Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and d- and L-(beta)-dideoxynucleoside triphosphate analogs. Antimicrob Agents Chemother 2001 0.84
107 Activation of DNA replication in yeast by recruitment of the RNA polymerase II transcription complex. Biol Chem 1999 0.84
108 Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs. Nucleic Acids Res 1999 0.83
109 Cloning and expression of a cDNA encoding a catalytically active fragment of calf thymus DNA polymerase alpha. Biochem Biophys Res Commun 1986 0.83
110 Quantitation with monoclonal antibodies of Escherichia coli H protein suggests histone function. J Bacteriol 1985 0.83
111 Phosphorylation of the PCNA binding domain of the large subunit of replication factor C by Ca2+/calmodulin-dependent protein kinase II inhibits DNA synthesis. Biochemistry 1997 0.82
112 Electron microscopic analysis reveals that replication factor C is sequestered by single-stranded DNA. Nucleic Acids Res 1999 0.82
113 Current understanding of UV-induced base pair substitution mutation in E. coli with particular reference to the DNA polymerase III complex. Mutat Res 1987 0.82
114 HIV-1 nucleocapsid protein and replication protein A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase. AIDS 1997 0.82
115 Functional genomics in HIV-1 virus replication: protein-protein interactions as a basis for recruiting the host cell machinery for viral propagation. Biol Chem 2001 0.82
116 4'-Acylated thymidine 5'-triphosphates: a tool to increase selectivity towards HIV-1 reverse transcriptase. Nucleic Acids Res 1998 0.81
117 Extra DNA in forebrain cortical neurons. Exp Cell Res 1978 0.81
118 Probing interactions between HIV-1 reverse transcriptase and its DNA substrate with backbone-modified nucleotides. Chem Biol 1999 0.80
119 The PCNA from Thermococcus fumicolans functionally interacts with DNA polymerase delta. Biochem Biophys Res Commun 2000 0.79
120 Intramolecular chimeras of the p51 subunit between HIV-1 and FIV reverse transcriptases suggest a stabilizing function for the p66 subunit in the heterodimeric enzyme. Biochemistry 1999 0.79
121 A double-loop model for the replication of eukaryotic DNA. Mutat Res 1989 0.79
122 Calcium-dependent calmodulin-binding proteins associated with mammalian DNA polymerase alpha. Biochim Biophys Acta 1988 0.79
123 Mammalian DNA polymerase alpha holoenzyme. Adv Exp Med Biol 1984 0.79
124 Replication of single-stranded porcine circovirus DNA by DNA polymerases alpha and delta. Biochim Biophys Acta 1988 0.78
125 Calf thymus Hsc70 and Hsc40 can substitute for DnaK and DnaJ function in protein renaturation but not in bacteriophage DNA replication. FEBS Lett 2001 0.77
126 Interaction studies between the p21Cip1/Waf1 cyclin-dependent kinase inhibitor and proliferating cell nuclear antigen (PCNA) by surface plasmon resonance. FEBS Lett 1996 0.77
127 HIV-reverse transcriptase and human DNA polymerase alpha share amino acid sequence homologies to bacterial penicillin-binding proteins. Methods Find Exp Clin Pharmacol 1990 0.77
128 HP 0.35, a cephalosporin degradation product is a specific inhibitor of lentiviral RNAses H. Nucleic Acids Res 1991 0.77
129 Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy-pyrimidine nucleoside triphosphates: molecular basis for the combination of L-dideoxynucleoside analogs with non-nucleoside inhibitors in anti HIV chemotherapy. Nucleosides Nucleotides 1999 0.77
130 Betalactam antibiotics interfere with eukaryotic DNA-replication by inhibiting DNA polymerase alpha. Nucleic Acids Res 1987 0.77
131 [Quantification of proviral FIV DNA using competitive PCR]. Schweiz Arch Tierheilkd 1996 0.76
132 The N-terminal region of DNA polymerase delta catalytic subunit is necessary for holoenzyme function. Nucleic Acids Res 2000 0.76
133 Interaction of cis-diamminedichloroplatinum (II) with single-stranded DNA in the presence or absence of Escherichia coli single-stranded binding protein. Biochem Pharmacol 1991 0.76
134 Mutant DNA polymerase delta from thermosensitive Schizosaccharomyces pombe strains display reduced stimulation by proliferating cell nuclear antigen. Biochem J 1998 0.75
135 The effect of drugs on mitochondrial DNA synthesis can be tested in isolated synaptosomes. Nucleic Acids Res 1986 0.75
136 Ultrastructural cryoimmunocytochemistry is a convenient tool for the study of DNA replication in cultured cells. J Electron Microsc Tech 1991 0.75
137 Cloning, chromosomal localization, and interspecies interaction of mouse DNA polymerase delta small subunit (PolD2). Genomics 1997 0.75
138 A reliable protocol for dsDNA and PCR product sequencing. Biotechniques 1993 0.75
139 [Gene technology and veterinary medicine. II. Vaccines produced by genetic technics and analysis of highly variable DNA segments]. Schweiz Arch Tierheilkd 1987 0.75
140 [Is health really the most important value? - Results of a representative survey of the German general population concerning the subjective meaning of health]. Gesundheitswesen 2010 0.75
141 [Analysis of microsatellite polymorphisms in Bernese mountain dogs and Newfoundlands]. Schweiz Arch Tierheilkd 1996 0.75
142 [Genetic technology in the service of veterinary medicine. II. Basic research as primary beneficiary]. Schweiz Arch Tierheilkd 1982 0.75
143 [The chicken egg as a supply of polyclonal antibodies]. Schweiz Arch Tierheilkd 1990 0.75
144 [Gene technology and veterinary medicine. III. Transgenic animals: facts and perspectives]. Schweiz Arch Tierheilkd 1987 0.75
145 Anti-HIV-1 activity in vitro of ceftazidime degradation products. Antivir Chem Chemother 2001 0.75
146 [DNA diagnosis in veterinary medicine: I. DNA fingerprinting]. Schweiz Arch Tierheilkd 1991 0.75
147 Effect of divalent and monovalent cations on calf thymus PCNA-independent DNA polymerase delta and its 3'----5' exonuclease. FEBS Lett 1990 0.75
148 [Gene technology and veterinary medicine. I. General principles and examples of practical application]. Schweiz Arch Tierheilkd 1987 0.75
149 Modified gel electrophoresis for higher resolution of DNA fingerprints. Nucleic Acids Res 1988 0.75
150 [PCR: basics and new developments]. Schweiz Arch Tierheilkd 1996 0.75
151 [Gene technology in the service of veterinary medicine]. Schweiz Arch Tierheilkd 1982 0.75
152 [Gene technology in the service of veterinary medicine. III. Applications in practical veterinary medicine and in agriculture]. Schweiz Arch Tierheilkd 1982 0.75
153 Two-dimensional DNA-fingerprinting in animals. EXS 1991 0.75
154 DNA methylation and DNA structure. Adv Exp Med Biol 1984 0.75
155 [DNA fingerprinting in wild equid and Poitou ass breeding]. Schweiz Arch Tierheilkd 1995 0.75