Marla Gearing

Author PubWeight™ 106.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet 2011 10.07
2 Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet 2010 5.52
3 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci 2011 4.15
4 Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol 2014 3.75
5 Loss of apolipoprotein E receptor LR11 in Alzheimer disease. Arch Neurol 2004 3.39
6 The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments. J Neurosci 2006 2.77
7 Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases. J Biol Chem 2006 2.50
8 Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases. J Biol Chem 2004 2.46
9 Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model. Exp Neurol 2003 2.46
10 Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration. Proc Natl Acad Sci U S A 2013 2.30
11 Hippocampal sclerosis in advanced age: clinical and pathological features. Brain 2011 2.16
12 Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy. Science 2009 2.13
13 Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology 2012 2.08
14 LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease. J Neuropathol Exp Neurol 2006 1.72
15 Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection. J Biol Chem 2004 1.58
16 alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease. Am J Pathol 2004 1.53
17 Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease. J Biol Chem 2011 1.48
18 Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet 2012 1.46
19 Neuronal LR11/sorLA expression is reduced in mild cognitive impairment. Ann Neurol 2007 1.45
20 alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases. Acta Neuropathol 2004 1.43
21 Deficient high-affinity binding of Pittsburgh compound B in a case of Alzheimer's disease. Acta Neuropathol 2009 1.42
22 Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease. J Proteome Res 2009 1.27
23 Tauopathy with paired helical filaments in an aged chimpanzee. J Comp Neurol 2008 1.27
24 U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proc Natl Acad Sci U S A 2013 1.23
25 Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion. Proc Natl Acad Sci U S A 2008 1.22
26 A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia. Am J Hum Genet 2006 1.20
27 Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities. EMBO J 2007 1.19
28 AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells. J Biol Chem 2004 1.19
29 Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS. Proc Natl Acad Sci U S A 2012 1.17
30 Neuropathological heterogeneity in frontotemporal lobar degeneration with TDP-43 proteinopathy: a quantitative study of 94 cases using principal components analysis. J Neural Transm (Vienna) 2009 1.14
31 Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry. J Proteome Res 2008 1.13
32 Proteomic identification of novel proteins associated with Lewy bodies. Front Biosci 2008 1.13
33 A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease. Neurobiol Dis 2009 1.11
34 Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration. J Proteome Res 2010 1.10
35 TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathol 2014 1.08
36 ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathol 2014 1.07
37 Mortalin: a protein associated with progression of Parkinson disease? J Neuropathol Exp Neurol 2008 1.07
38 Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards. J Proteome Res 2012 1.05
39 Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID). Neurobiol Aging 2005 1.04
40 Relationship between Serum and Brain Carotenoids, α-Tocopherol, and Retinol Concentrations and Cognitive Performance in the Oldest Old from the Georgia Centenarian Study. J Aging Res 2013 1.03
41 β-Hexachlorocyclohexane levels in serum and risk of Parkinson's disease. Neurotoxicology 2011 1.03
42 Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Arch Neurol 2011 1.01
43 PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain. J Neuropathol Exp Neurol 2007 0.99
44 Understanding dementia prevalence among centenarians. J Gerontol A Biol Sci Med Sci 2012 0.99
45 Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production. J Biol Chem 2010 0.99
46 Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease. Free Radic Biol Med 2008 0.98
47 Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease. Proteomics Clin Appl 2012 0.98
48 Neuron enriched nuclear proteome isolated from human brain. J Proteome Res 2013 0.97
49 Glycoproteomics in neurodegenerative diseases. Mass Spectrom Rev 2009 0.94
50 Asparaginyl endopeptidase cleaves TDP-43 in brain. Proteomics 2012 0.93
51 Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease. Acta Neuropathol 2005 0.90
52 Proteomics identification of proteins in human cortex using multidimensional separations and MALDI tandem mass spectrometer. Mol Cell Proteomics 2007 0.89
53 FUS immunogold labeling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy. J Mol Neurosci 2011 0.88
54 Fas-associated factor 1 and Parkinson's disease. Neurobiol Dis 2008 0.88
55 Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain. Neurosci Lett 2012 0.87
56 The spectrum and severity of FUS-immunoreactive inclusions in the frontal and temporal lobes of ten cases of neuronal intermediate filament inclusion disease. Acta Neuropathol 2010 0.87
57 Identification of proteins in human substantia nigra. Proteomics Clin Appl 2008 0.86
58 Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration. Mol Neurodegener 2011 0.84
59 Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol 2015 0.84
60 Characterization of osteopontin expression and function after status epilepticus. Epilepsia 2008 0.83
61 Association between polychlorinated biphenyls and Parkinson's disease neuropathology. Neurotoxicology 2012 0.83
62 Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology. Front Neurol 2011 0.81
63 Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease. Brain Pathol 2014 0.80
64 NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease. Neurosci Lett 2013 0.80
65 Amphiphysin-1 protein level changes associated with tau-mediated neurodegeneration. Neuroreport 2012 0.80
66 RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells. Neurobiol Dis 2013 0.80
67 U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21. Mol Neurodegener 2014 0.80
68 Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes. J Neuropathol Exp Neurol 2013 0.79
69 Ovarian histopathological and ubiquitin-immunophenotypic features in fragile X-associated primary ovarian insufficiency: a study of five cases and selected controls. Histopathology 2011 0.78
70 Successful Recruitment of Centenarians for Post-Mortem Brain Donation: Results from the Georgia Centenarian Study. J Biosci Med 2012 0.78
71 Loss of dopamine phenotype among midbrain neurons in Lesch-Nyhan disease. Ann Neurol 2014 0.78
72 Spatial patterns of FUS-immunoreactive neuronal cytoplasmic inclusions (NCI) in neuronal intermediate filament inclusion disease (NIFID). J Neural Transm (Vienna) 2011 0.77
73 Hirano bodies differentially modulate cell death induced by tau and the amyloid precursor protein intracellular domain. BMC Neurosci 2014 0.77