Published in Free Radic Biol Med on July 12, 2006
Mitochondrial energetics and therapeutics. Annu Rev Pathol (2010) 3.07
Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging? Free Radic Biol Med (2009) 2.00
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity. J Gerontol A Biol Sci Med Sci (2009) 1.65
Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal (2011) 1.57
Bone marrow-derived cell regulation of skeletal muscle regeneration. FASEB J (2008) 1.11
A reducing redox environment promotes C2C12 myogenesis: implications for regeneration in aged muscle. Cell Biol Int (2006) 1.11
Age-dependent alteration in muscle regeneration: the critical role of tissue niche. Biogerontology (2013) 1.02
Temporal microRNA expression during in vitro myogenic progenitor cell proliferation and differentiation: regulation of proliferation by miR-682. Physiol Genomics (2010) 0.99
The radiosensitivity of satellite cells: cell cycle regulation, apoptosis and oxidative stress. Radiat Res (2010) 0.91
Biological approaches to improve skeletal muscle healing after injury and disease. Birth Defects Res C Embryo Today (2012) 0.91
Role of reactive oxygen species in the defective regeneration seen in aging muscle. Free Radic Biol Med (2013) 0.90
Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration. Proc Natl Acad Sci U S A (2013) 0.87
The role of oxidative stress in skeletal muscle injury and regeneration: focus on antioxidant enzymes. J Muscle Res Cell Motil (2016) 0.85
MicroRNA miR-378 promotes BMP2-induced osteogenic differentiation of mesenchymal progenitor cells. BMC Mol Biol (2014) 0.85
Manipulation of environmental oxygen modifies reactive oxygen and nitrogen species generation during myogenesis. Redox Biol (2016) 0.82
Satellite cells say NO to radiation. Radiat Res (2011) 0.82
Effect of oxygen tension on bioenergetics and proteostasis in young and old myoblast precursor cells. Redox Biol (2013) 0.80
Comparative transcriptome profiling of longissimus muscle tissues from Qianhua Mutton Merino and Small Tail Han sheep. Sci Rep (2016) 0.77
Extension of murine life span by overexpression of catalase targeted to mitochondria. Science (2005) 10.11
Trends in oxidative aging theories. Free Radic Biol Med (2007) 4.51
Complex III releases superoxide to both sides of the inner mitochondrial membrane. J Biol Chem (2004) 3.59
CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene (2005) 3.17
Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radic Biol Med (2006) 3.04
Is the oxidative stress theory of aging dead? Biochim Biophys Acta (2009) 2.86
Insulin resistance is a cellular antioxidant defense mechanism. Proc Natl Acad Sci U S A (2009) 2.60
Reproducibility of quantitative RT-PCR array in miRNA expression profiling and comparison with microarray analysis. BMC Genomics (2009) 2.39
Methionine oxidation and aging. Biochim Biophys Acta (2005) 2.37
High oxidative damage levels in the longest-living rodent, the naked mole-rat. Aging Cell (2006) 2.31
The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults. Free Radic Biol Med (2003) 2.30
The overexpression of major antioxidant enzymes does not extend the lifespan of mice. Aging Cell (2008) 2.25
Fabrication of reconfigurable protein matrices by cracking. Nat Mater (2005) 2.08
Lifespan extension in genetically modified mice. Aging Cell (2009) 1.98
Overexpression of Mn superoxide dismutase does not increase life span in mice. J Gerontol A Biol Sci Med Sci (2009) 1.98
Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration. FASEB J (2009) 1.78
Fat accumulation with altered inflammation and regeneration in skeletal muscle of CCR2-/- mice following ischemic injury. Am J Physiol Cell Physiol (2006) 1.74
Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production. Am J Physiol Regul Integr Comp Physiol (2007) 1.70
Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging. Mech Ageing Dev (2006) 1.67
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity. J Gerontol A Biol Sci Med Sci (2009) 1.65
Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis. J Biol Chem (2004) 1.60
Delayed angiogenesis and VEGF production in CCR2-/- mice during impaired skeletal muscle regeneration. Am J Physiol Regul Integr Comp Physiol (2007) 1.58
The in vivo gene expression signature of oxidative stress. Physiol Genomics (2008) 1.55
Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis. J Gerontol A Biol Sci Med Sci (2007) 1.47
Studies of mitochondrial and nonmitochondrial sources implicate nicotinamide adenine dinucleotide phosphate oxidase(s) in the increased skeletal muscle superoxide generation that occurs during contractile activity. Antioxid Redox Signal (2012) 1.46
High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates. Biochem J (2008) 1.44
Effects of age and caloric restriction on lipid peroxidation: measurement of oxidative stress by F2-isoprostane levels. J Gerontol A Biol Sci Med Sci (2005) 1.41
The mitochondrial theory of aging: insight from transgenic and knockout mouse models. Exp Gerontol (2009) 1.39
Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models? Free Radic Biol Med (2011) 1.35
Immune cell Toll-like receptor 4 is required for cardiac myocyte impairment during endotoxemia. Circ Res (2004) 1.35
Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress. FEBS Lett (2002) 1.32
Age-associated alterations of the neuromuscular junction. Exp Gerontol (2010) 1.26
Detection of protein carbonyls in aging liver tissue: A fluorescence-based proteomic approach. Mech Ageing Dev (2006) 1.24
Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor kappaB activation. J Physiol (2008) 1.24
Deleterious action of FA metabolites on ATP synthesis: possible link between lipotoxicity, mitochondrial dysfunction, and insulin resistance. Am J Physiol Endocrinol Metab (2008) 1.23
Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress. Free Radic Biol Med (2007) 1.22
Age-related cardiac muscle sarcopenia: Combining experimental and mathematical modeling to identify mechanisms. Exp Gerontol (2007) 1.20
Age-related cataract progression in five mouse models for anti-oxidant protection or hormonal influence. Exp Eye Res (2005) 1.20
A strategy for the ubiquitous overexpression of human catalase and CuZn superoxide dismutase genes in transgenic mice. Mech Ageing Dev (2003) 1.18
Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice. Aging Cell (2008) 1.18
Characterization of transgenic mice that overexpress both copper zinc superoxide dismutase and catalase. Antioxid Redox Signal (2006) 1.16
Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity. Am J Physiol Cell Physiol (2009) 1.16
Exercise and skeletal muscle ageing: cellular and molecular mechanisms. Ageing Res Rev (2002) 1.14
Is oxidative stress a physiological cost of reproduction? An experimental test in house mice. Proc Biol Sci (2010) 1.13
Regulation of skeletal muscle regeneration by CCR2-activating chemokines is directly related to macrophage recruitment. Am J Physiol Regul Integr Comp Physiol (2010) 1.13
Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase. Aging Cell (2011) 1.12
Intracellular generation of reactive oxygen species by contracting skeletal muscle cells. Free Radic Biol Med (2005) 1.12
Bone marrow-derived cell regulation of skeletal muscle regeneration. FASEB J (2008) 1.11
Different death stimuli evoke apoptosis via multiple pathways in retinal pigment epithelial cells. Exp Eye Res (2006) 1.07
Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose tolerance. Diabetes (2011) 1.07
Gpx4 protects mitochondrial ATP generation against oxidative damage. Biochem Biophys Res Commun (2007) 1.07
Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity. J Neurosci Res (2006) 1.05
Catalase transgenic mice: characterization and sensitivity to oxidative stress. Arch Biochem Biophys (2004) 1.04
Denervation induces cytosolic phospholipase A2-mediated fatty acid hydroperoxide generation by muscle mitochondria. J Biol Chem (2008) 1.04
p53 Regulates oxidative stress-mediated retrograde signaling: a novel mechanism for chemotherapy-induced cardiac injury. PLoS One (2011) 1.03
Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD. Aging Cell (2012) 1.03
Chemokines and diabetic wound healing. Vascular (2007) 1.03
The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase. Aging Cell (2010) 1.03
Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation. Am J Physiol Regul Integr Comp Physiol (2011) 1.01
Temporal microRNA expression during in vitro myogenic progenitor cell proliferation and differentiation: regulation of proliferation by miR-682. Physiol Genomics (2010) 0.99
Loss of manganese superoxide dismutase leads to abnormal growth and signal transduction in mouse embryonic fibroblasts. Free Radic Biol Med (2010) 0.99
Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice. J Gerontol A Biol Sci Med Sci (2011) 0.99
Processing of data generated by 2-dimensional gel electrophoresis for statistical analysis: missing data, normalization, and statistics. J Proteome Res (2004) 0.99
Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts. Aging Cell (2013) 0.99
Mechanical buckling of veins under internal pressure. Ann Biomed Eng (2010) 0.99
Reduced coupling of oxidative phosphorylation in vivo precedes electron transport chain defects due to mild oxidative stress in mice. PLoS One (2011) 0.99
Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice. FASEB J (2013) 0.98
Embryonic fibroblasts from Gpx4+/- mice: a novel model for studying the role of membrane peroxidation in biological processes. Free Radic Biol Med (2003) 0.98
MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging. Aging Cell (2011) 0.97
The role of insulin and insulin-like growth factor-I in mammalian ageing. Best Pract Res Clin Endocrinol Metab (2004) 0.97
Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain. Free Radic Biol Med (2012) 0.95
Near-infrared imaging of injured tissue in living subjects using IR-820. Mol Imaging (2009) 0.95
CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice. FASEB J (2013) 0.95
Formation of 3-nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle. Proteomics Clin Appl (2007) 0.95
Adaptive changes in structure of skeletal muscles from adult Sod1 homozygous knockout mice. Cell Tissue Res (2006) 0.94
MiR-351 transiently increases during muscle regeneration and promotes progenitor cell proliferation and survival upon differentiation. Physiol Genomics (2012) 0.94
Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria. Free Radic Biol Med (2009) 0.94
Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels. Biochem Biophys Res Commun (2012) 0.94
Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus. Am J Physiol Regul Integr Comp Physiol (2013) 0.94
GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis. J Mol Biol (2008) 0.93
Dietary restriction but not rapamycin extends disease onset and survival of the H46R/H48Q mouse model of ALS. Neurobiol Aging (2011) 0.93
PGC-1α protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model. Muscle Nerve (2011) 0.93
Sod2 overexpression preserves myoblast mitochondrial mass and function, but not muscle mass with aging. Aging Cell (2009) 0.93
Improved insulin sensitivity associated with reduced mitochondrial complex IV assembly and activity. FASEB J (2012) 0.92
A novel approach for screening the proteome for changes in protein conformation. Biochemistry (2006) 0.92
Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice. J Cereb Blood Flow Metab (2013) 0.91
Skeletal muscle damage with exercise and aging. Sports Med (2005) 0.90
Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells. Cancer Prev Res (Phila) (2011) 0.90
Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates. Toxicol Appl Pharmacol (2008) 0.90
Current concepts in diabetic microvascular dysfunction. J Am Podiatr Med Assoc (2006) 0.89
HSF expression in skeletal muscle during myogenesis: implications for failed regeneration in old mice. Exp Gerontol (2006) 0.88
Angiographic scoring of vascular occlusive disease in the diabetic foot: relevance to bypass graft patency and limb salvage. J Vasc Surg (2002) 0.88
Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses. Biochem J (2014) 0.88
Major lower-extremity amputation: contemporary experience in a single Veterans Affairs institution. Am Surg (2002) 0.88
Age-related loss of the DNA repair response following exposure to oxidative stress. J Gerontol A Biol Sci Med Sci (2006) 0.86
Overexpression of antioxidant enzymes in diaphragm muscle does not alter contraction-induced fatigue or recovery. Exp Physiol (2009) 0.86
Mitochondrial dysfunction in aging and longevity: a causal or protective role? Antioxid Redox Signal (2012) 0.86
Elevated protein carbonylation, and misfolding in sciatic nerve from db/db and Sod1(-/-) mice: plausible link between oxidative stress and demyelination. PLoS One (2013) 0.86