| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo.
|
Blood
|
2011
|
5.06
|
|
2
|
In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells.
|
J Clin Invest
|
2005
|
3.99
|
|
3
|
Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia.
|
J Exp Med
|
2004
|
2.79
|
|
4
|
Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity.
|
J Clin Invest
|
2005
|
2.40
|
|
5
|
Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA).
|
Blood
|
2008
|
2.35
|
|
6
|
High mobility group box protein 1: an endogenous signal for dendritic cell maturation and Th1 polarization.
|
J Immunol
|
2004
|
2.32
|
|
7
|
Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin.
|
Blood
|
2010
|
2.23
|
|
8
|
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies.
|
Blood
|
2012
|
2.14
|
|
9
|
A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease.
|
Blood
|
2011
|
2.09
|
|
10
|
Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia.
|
J Clin Invest
|
2004
|
1.94
|
|
11
|
B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes.
|
Blood
|
2002
|
1.94
|
|
12
|
Characterization of structurally defined epitopes recognized by monoclonal antibodies produced by chronic lymphocytic leukemia B cells.
|
Blood
|
2009
|
1.89
|
|
13
|
Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation.
|
Mol Med
|
2008
|
1.82
|
|
14
|
Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status.
|
Blood
|
2005
|
1.74
|
|
15
|
B cell receptor signaling in chronic lymphocytic leukemia.
|
Trends Immunol
|
2013
|
1.72
|
|
16
|
CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells.
|
Blood
|
2007
|
1.69
|
|
17
|
FCRL2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemia.
|
Blood
|
2008
|
1.67
|
|
18
|
Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA.
|
Blood
|
2008
|
1.67
|
|
19
|
B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia.
|
Proc Natl Acad Sci U S A
|
2006
|
1.55
|
|
20
|
CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice.
|
J Clin Invest
|
2003
|
1.52
|
|
21
|
Chronic lymphocytic leukemia B cells can undergo somatic hypermutation and intraclonal immunoglobulin V(H)DJ(H) gene diversification.
|
J Exp Med
|
2002
|
1.45
|
|
22
|
In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia.
|
Blood
|
2009
|
1.40
|
|
23
|
The pattern and distribution of immunoglobulin VH gene mutations in chronic lymphocytic leukemia B cells are consistent with the canonical somatic hypermutation process.
|
Blood
|
2003
|
1.35
|
|
24
|
CD38 and chronic lymphocytic leukemia: a decade later.
|
Blood
|
2011
|
1.33
|
|
25
|
Telomere length and telomerase activity delineate distinctive replicative features of the B-CLL subgroups defined by immunoglobulin V gene mutations.
|
Blood
|
2003
|
1.30
|
|
26
|
Intraclonal complexity in chronic lymphocytic leukemia: fractions enriched in recently born/divided and older/quiescent cells.
|
Mol Med
|
2011
|
1.29
|
|
27
|
Activation-induced cytidine deaminase in chronic lymphocytic leukemia B cells: expression as multiple forms in a dynamic, variably sized fraction of the clone.
|
Blood
|
2003
|
1.20
|
|
28
|
Biology and treatment of chronic lymphocytic leukemia.
|
Hematology Am Soc Hematol Educ Program
|
2003
|
1.18
|
|
29
|
Clonal heterogeneity in chronic lymphocytic leukemia cells: superior response to surface IgM cross-linking in CD38, ZAP-70-positive cells.
|
Haematologica
|
2008
|
1.09
|
|
30
|
Chronic lymphocytic leukaemia: a disease of activated monoclonal B cells.
|
Best Pract Res Clin Haematol
|
2010
|
1.07
|
|
31
|
B cell proliferation, somatic hypermutation, class switch recombination, and autoantibody production in ectopic lymphoid tissue in murine lupus.
|
J Immunol
|
2009
|
1.06
|
|
32
|
Dendritic cell activating peptides induce distinct cytokine profiles.
|
Int Immunol
|
2006
|
1.05
|
|
33
|
Th17 and non-Th17 interleukin-17-expressing cells in chronic lymphocytic leukemia: delineation, distribution, and clinical relevance.
|
Haematologica
|
2011
|
0.99
|
|
34
|
Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signaling.
|
Proc Natl Acad Sci U S A
|
2013
|
0.97
|
|
35
|
Identification of outcome-correlated cytokine clusters in chronic lymphocytic leukemia.
|
Blood
|
2011
|
0.97
|
|
36
|
The global transcriptional maturation program and stimuli-specific gene expression profiles of human myeloid dendritic cells.
|
Int Immunol
|
2003
|
0.96
|
|
37
|
CD5+ B cells with the features of subepithelial B cells found in human tonsils.
|
Eur J Immunol
|
2007
|
0.95
|
|
38
|
The CD38 ectoenzyme family: advances in basic science and clinical practice.
|
Mol Med
|
2007
|
0.94
|
|
39
|
The human marginal zone B cell.
|
Ann N Y Acad Sci
|
2003
|
0.92
|
|
40
|
IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions.
|
Blood
|
2012
|
0.91
|
|
41
|
TSP50, a possible protease in human testes, is activated in breast cancer epithelial cells.
|
Cancer Res
|
2002
|
0.90
|
|
42
|
Association between B-cell receptor responsiveness and disease progression in B-cell chronic lymphocytic leukemia: results from single cell network profiling studies.
|
Haematologica
|
2012
|
0.88
|
|
43
|
Mutation pattern of paired immunoglobulin heavy and light variable domains in chronic lymphocytic leukemia B cells.
|
Mol Med
|
2011
|
0.88
|
|
44
|
Torque teno virus 10 isolated by genome amplification techniques from a patient with concomitant chronic lymphocytic leukemia and polycythemia vera.
|
Mol Med
|
2011
|
0.88
|
|
45
|
Genomic imbalance defines three prognostic groups for risk stratification of patients with chronic lymphocytic leukemia.
|
Leuk Lymphoma
|
2013
|
0.88
|
|
46
|
Igs expressed by chronic lymphocytic leukemia B cells show limited binding-site structure variability.
|
J Immunol
|
2013
|
0.88
|
|
47
|
Diversification of the Ig variable region gene repertoire of synovial B lymphocytes by nucleotide insertion and deletion.
|
Mol Med
|
2003
|
0.87
|
|
48
|
Surface expression of Bcl-2 in chronic lymphocytic leukemia and other B-cell leukemias and lymphomas without a breakpoint t(14;18).
|
Mol Med
|
2008
|
0.86
|
|
49
|
Analysis of single nucleotide polymorphisms in the promoter region of interleukin-10 by denaturing high-performance liquid chromatography.
|
J Biomol Tech
|
2005
|
0.86
|
|
50
|
B lymphocytes in humans express ZAP-70 when activated in vivo.
|
Eur J Immunol
|
2006
|
0.85
|
|
51
|
Recent advances in the molecular biology and immunobiology of chronic lymphocytic leukemia.
|
Semin Hematol
|
2004
|
0.85
|
|
52
|
Determining the clinical course and outcome in chronic lymphocytic leukemia.
|
N Engl J Med
|
2003
|
0.85
|
|
53
|
Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cells.
|
Blood
|
2011
|
0.84
|
|
54
|
Maintenance of B lymphocyte-related clones in the cerebrospinal fluid of multiple sclerosis patients.
|
Eur J Immunol
|
2003
|
0.84
|
|
55
|
Constitutive and activation-inducible cyclooxygenase-2 expression enhances survival of chronic lymphocytic leukemia B cells.
|
Clin Immunol
|
2006
|
0.84
|
|
56
|
A cyclooxygenase-2/prostaglandin E2 pathway augments activation-induced cytosine deaminase expression within replicating human B cells.
|
J Immunol
|
2010
|
0.84
|
|
57
|
Similarities and differences between the light and heavy chain Ig variable region gene repertoires in chronic lymphocytic leukemia.
|
Mol Med
|
2007
|
0.84
|
|
58
|
Lack of deleterious somatic mutations in the CD95 gene of plasmablasts from systemic lupus erythematosus patients and autoantibody-producing cell lines.
|
Eur J Immunol
|
2002
|
0.83
|
|
59
|
Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia.
|
Immunogenetics
|
2014
|
0.83
|
|
60
|
Lifespan is prolonged in autoimmune-prone (NZB/NZW) F1 mice fed a diet supplemented with indole-3-carbinol.
|
J Nutr
|
2003
|
0.83
|
|
61
|
CD180 functions in activation, survival and cycling of B chronic lymphocytic leukaemia cells.
|
Br J Haematol
|
2011
|
0.83
|
|
62
|
Peptides that bind specifically to an antibody from a chronic lymphocytic leukemia clone expressing unmutated immunoglobulin variable region genes.
|
Mol Med
|
2013
|
0.82
|
|
63
|
Enhanced expression of mRNA for nuclear factor kappaB1 (p50) in CD34+ cells of the bone marrow in rheumatoid arthritis.
|
Arthritis Res Ther
|
2006
|
0.82
|
|
64
|
Isolation of malignant B cells from patients with chronic lymphocytic leukemia (CLL) for analysis of cell proliferation: validation of a simplified method suitable for multi-center clinical studies.
|
Leuk Res
|
2009
|
0.81
|
|
65
|
Chronic lymphocytic leukemia: new concepts for future therapy.
|
Clin Lymphoma Myeloma Leuk
|
2010
|
0.81
|
|
66
|
T-cell independent, B-cell receptor-mediated induction of telomerase activity differs among IGHV mutation-based subgroups of chronic lymphocytic leukemia patients.
|
Blood
|
2012
|
0.81
|
|
67
|
Colocalization of antigen-specific B and T cells within ectopic lymphoid tissue following immunization with exogenous antigen.
|
J Immunol
|
2008
|
0.80
|
|
68
|
Internal standard-based analysis of microarray data2--analysis of functional associations between HVE-genes.
|
Nucleic Acids Res
|
2011
|
0.79
|
|
69
|
Where is the biology of CLL leading us?
|
Semin Cancer Biol
|
2010
|
0.79
|
|
70
|
Effects of prostaglandin E2 on p53 mRNA transcription and p53 mutagenesis during T-cell-independent human B-cell clonal expansion.
|
FASEB J
|
2013
|
0.77
|
|
71
|
A p53 axis regulates B cell receptor-triggered, innate immune system-driven B cell clonal expansion.
|
J Immunol
|
2012
|
0.77
|
|
72
|
Indole-3-carbinol improves survival in lupus-prone mice by inducing tandem B- and T-cell differentiation blockades.
|
Clin Immunol
|
2009
|
0.77
|
|
73
|
Dendritic cells from chronic lymphocytic leukemia patients are normal regardless of Ig V gene mutation status.
|
Mol Med
|
2006
|
0.76
|