Hypoxic pulmonary vasoconstriction is/is not mediated by increased production of reactive oxygen species.

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Counterpoint: Hypoxic pulmonary vasoconstriction is not mediated by increased production of reactive oxygen species. J Appl Physiol (1985) (2006) 2.48

NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature (2009) 4.41

Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation. Cell Metab (2010) 4.14

Lysosome-sarcoplasmic reticulum junctions. A trigger zone for calcium signaling by nicotinic acid adenine dinucleotide phosphate and endothelin-1. J Biol Chem (2004) 1.88

Carotid body denervation prevents the development of insulin resistance and hypertension induced by hypercaloric diets. Diabetes (2013) 1.64

Nicotinic acid adenine dinucleotide phosphate mediates Ca2+ signals and contraction in arterial smooth muscle via a two-pool mechanism. Circ Res (2002) 1.45

AMP-activated protein kinase mediates carotid body excitation by hypoxia. J Biol Chem (2006) 1.32

Calcium signaling via two-pore channels: local or global, that is the question. Am J Physiol Cell Physiol (2009) 1.26

TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP. FEBS Lett (2010) 1.26

The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels. Pflugers Arch (2009) 1.19

Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability. Proc Natl Acad Sci U S A (2011) 1.15

Mechanisms for acute oxygen sensing in the carotid body. Respir Physiol Neurobiol (2010) 1.15

Lysosomes co-localize with ryanodine receptor subtype 3 to form a trigger zone for calcium signalling by NAADP in rat pulmonary arterial smooth muscle. Cell Calcium (2008) 1.08

Cyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels. J Biol Chem (2011) 1.06

Molecular identification of Kvalpha subunits that contribute to the oxygen-sensitive K+ current of chemoreceptor cells of the rabbit carotid body. J Physiol (2002) 1.03

Vasodilation by the calcium-mobilizing messenger cyclic ADP-ribose. J Biol Chem (2002) 0.98

Selective expression in carotid body type I cells of a single splice variant of the large conductance calcium- and voltage-activated potassium channel confers regulation by AMP-activated protein kinase. J Biol Chem (2011) 0.94

Effects of low glucose on carotid body chemoreceptor cell activity studied in cultures of intact organs and in dissociated cells. Am J Physiol Cell Physiol (2011) 0.93

Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats. Br J Nutr (2011) 0.91

Identification of functionally segregated sarcoplasmic reticulum calcium stores in pulmonary arterial smooth muscle. J Biol Chem (2010) 0.89

An emerging role for NAADP-mediated Ca2+ signaling in the pancreatic β-cell. Islets (2010) 0.89

AMP-activated protein kinase and hypoxic pulmonary vasoconstriction. Eur J Pharmacol (2008) 0.89

A proximal arginine R206 participates in switching of the Bradyrhizobium japonicum FixL oxygen sensor. J Mol Biol (2006) 0.87

Two-pore channels for integrative Ca signaling. Commun Integr Biol (2010) 0.86

Molecular identification and functional role of voltage-gated sodium channels in rat carotid body chemoreceptor cells. Regulation of expression by chronic hypoxia in vivo. J Neurochem (2007) 0.85

The human carotid body transcriptome with focus on oxygen sensing and inflammation--a comparative analysis. J Physiol (2012) 0.85

Transcriptional profiling and genotyping of degraded nucleic acids from autopsy tissue samples after prolonged formalin fixation times. Int J Clin Exp Pathol (2011) 0.85

Neutral sphingomyelinase, NADPH oxidase and reactive oxygen species. Role in acute hypoxic pulmonary vasoconstriction. J Cell Physiol (2011) 0.84

MaxiK potassium channels in the function of chemoreceptor cells of the rat carotid body. Am J Physiol Cell Physiol (2009) 0.83

EPAC signalling pathways are involved in low PO2 chemoreception in carotid body chemoreceptor cells. J Physiol (2009) 0.82

Key roles for AMP-activated protein kinase in the function of the carotid body? Adv Exp Med Biol (2008) 0.81

General redox environment and carotid body chemoreceptor function. Am J Physiol Cell Physiol (2009) 0.81

Pan-junctional sarcoplasmic reticulum in vascular smooth muscle: nanospace Ca2+ transport for site- and function-specific Ca2+ signalling. J Physiol (2013) 0.81

The effects of intermittent hypoxia on redox status, NF-κB activation, and plasma lipid levels are dependent on the lowest oxygen saturation. Free Radic Biol Med (2013) 0.80

Functional identification of Kvalpha subunits contributing to the O2-sensitive K+ current in rabbit carotid body chemoreceptor cells. Adv Exp Med Biol (2003) 0.79

An antagonistic interaction between A2B adenosine and D2 dopamine receptors modulates the function of rat carotid body chemoreceptor cells. J Neurochem (2008) 0.78

Function of the rat carotid body chemoreceptors in ageing. J Neurochem (2006) 0.78

Effects of cigarette smoke and chronic hypoxia on airways remodeling and resistance. Clinical significance. Respir Physiol Neurobiol (2011) 0.78

Effects of cigarette smoke and chronic hypoxia on ventilation in guinea pigs. Clinical significance. Adv Exp Med Biol (2012) 0.77

Chronic caffeine intake in adult rat inhibits carotid body sensitization produced by chronic sustained hypoxia but maintains intact chemoreflex output. Mol Pharmacol (2012) 0.77

AMP-activated protein kinase and chemotransduction in the carotid body. Respir Physiol Neurobiol (2007) 0.77

Effect of chronic caffeine intake on carotid body catecholamine dynamics in control and chronically hypoxic rats. Adv Exp Med Biol (2012) 0.77

The use of NK-1 receptor null mice to assess the significance of substance P in the carotid body function. Adv Exp Med Biol (2003) 0.76

A reevaluation of the mechanisms involved in the secretion of catecholamine evoked by 2,4-dinitrophenol from chemoreceptor cells of the rabbit carotid body. Adv Exp Med Biol (2003) 0.76

Serotonin dynamics and actions in the rat carotid body: preliminary findings. Adv Exp Med Biol (2012) 0.76

Cyclic AMP and Epac contribute to the genesis of the positive interaction between hypoxia and hypercapnia in the carotid body. Adv Exp Med Biol (2012) 0.76

Tetrodotoxin as a tool to elucidate sensory transduction mechanisms: the case for the arterial chemoreceptors of the carotid body. Mar Drugs (2011) 0.75

Moderate ethanol ingestion, redox status, and cardiovascular system in the rat. Alcohol (2010) 0.75

Interactions between postnatal sustained hypoxia and intermittent hypoxia in the adulthood to alter brainstem structures and respiratory function. Adv Exp Med Biol (2012) 0.75