Published in Traffic on September 19, 2006
Endocytosis and intracellular trafficking of ErbBs. Exp Cell Res (2008) 1.96
EGF receptor trafficking: consequences for signaling and cancer. Trends Cell Biol (2013) 1.77
Molecular mechanisms of clathrin-independent endocytosis. J Cell Sci (2009) 1.72
Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancer. Histochem Cell Biol (2008) 1.65
Endocytosis and signaling: cell logistics shape the eukaryotic cell plan. Physiol Rev (2012) 1.61
Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity. Histochem Cell Biol (2008) 1.46
Endocytic trafficking of activated EGFR is AP-2 dependent and occurs through preformed clathrin spots. J Cell Sci (2009) 1.37
The regulation of cell-cell adhesion during epithelial-mesenchymal transition, motility and tumor progression. Cell Adh Migr (2012) 1.34
Endocytic adaptors--social networking at the plasma membrane. J Cell Sci (2011) 1.29
Epidermal growth factor receptor and cancer: control of oncogenic signalling by endocytosis. J Cell Mol Med (2008) 1.27
Threshold-controlled ubiquitination of the EGFR directs receptor fate. EMBO J (2013) 1.11
Clathrin-independent internalization and recycling. J Cell Mol Med (2007) 1.06
Internalization mechanisms of the epidermal growth factor receptor after activation with different ligands. PLoS One (2013) 0.99
Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor. EMBO J (2009) 0.90
Effects of membrane trafficking on signaling by receptor tyrosine kinases. Cold Spring Harb Perspect Biol (2013) 0.87
The epsin protein family: coordinators of endocytosis and signaling. Biomol Concepts (2012) 0.85
Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17. Cell Death Dis (2014) 0.84
Systems biological analysis of epidermal growth factor receptor internalization dynamics for altered receptor levels. J Biol Chem (2009) 0.82
Scratching the surface: actin' and other roles for the C-terminal Eps15 homology domain protein, EHD2. Histol Histopathol (2013) 0.80
A Christianson syndrome-linked deletion mutation (∆(287)ES(288)) in SLC9A6 disrupts recycling endosomal function and elicits neurodegeneration and cell death. Mol Neurodegener (2016) 0.75
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nat Cell Biol (2002) 5.83
Caveolae are highly immobile plasma membrane microdomains, which are not involved in constitutive endocytic trafficking. Mol Biol Cell (2002) 2.84
Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies. J Cell Biol (2002) 2.81
Membrane ruffling and macropinocytosis in A431 cells require cholesterol. J Cell Sci (2002) 2.02
Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation. Exp Cell Res (2004) 1.96
Transport of protein toxins into cells: pathways used by ricin, cholera toxin and Shiga toxin. FEBS Lett (2002) 1.92
Membrane traffic exploited by protein toxins. Annu Rev Cell Dev Biol (2002) 1.87
Differential effects of EGFR ligands on endocytic sorting of the receptor. Traffic (2009) 1.83
Caveolae: anchored, multifunctional platforms in the lipid ocean. Trends Cell Biol (2003) 1.75
Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancer. Histochem Cell Biol (2008) 1.65
Association with membrane protrusions makes ErbB2 an internalization-resistant receptor. Mol Biol Cell (2004) 1.63
Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae. J Cell Sci (2002) 1.59
Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding. J Biol Chem (2002) 1.54
Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits. Mol Cell Biol (2006) 1.54
Inhibitors of COP-mediated transport and cholera toxin action inhibit simian virus 40 infection. Mol Biol Cell (2002) 1.53
Clathrin-independent endocytosis: mechanisms and function. Curr Opin Cell Biol (2011) 1.53
Activation of the EGFR gene target EphA2 inhibits epidermal growth factor-induced cancer cell motility. Mol Cancer Res (2007) 1.52
Pathways followed by ricin and Shiga toxin into cells. Histochem Cell Biol (2001) 1.51
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking. Exp Cell Res (2007) 1.46
Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity. Histochem Cell Biol (2008) 1.46
Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2. Int J Cancer (2005) 1.41
Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits. Traffic (2008) 1.39
EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes. Carcinogenesis (2007) 1.35
The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly. EMBO J (2004) 1.34
Pathways followed by protein toxins into cells. Int J Med Microbiol (2004) 1.34
Caveolae: stable membrane domains with a potential for internalization. Traffic (2005) 1.24
Internalization and intracellular sorting of the EGF receptor: a model for understanding the mechanisms of receptor trafficking. J Cell Sci (2009) 1.24
The inhibitory effect of ErbB2 on epidermal growth factor-induced formation of clathrin-coated pits correlates with retention of epidermal growth factor receptor-ErbB2 oligomeric complexes at the plasma membrane. Mol Biol Cell (2005) 1.22
Geldanamycin stimulates internalization of ErbB2 in a proteasome-dependent way. J Cell Sci (2005) 1.19
Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes. Blood (2006) 1.13
Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus. Mol Biol Cell (2007) 1.11
Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism. Traffic (2005) 1.11
An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor. J Cell Biol (2008) 1.08
SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma. J Lipid Res (2007) 1.05
Retrograde transport of protein toxins through the Golgi apparatus. Histochem Cell Biol (2013) 1.03
Pertuzumab increases epidermal growth factor receptor down-regulation by counteracting epidermal growth factor receptor-ErbB2 heterodimerization. Mol Cancer Ther (2009) 1.03
Stimulus-dependent regulation of the phagocyte NADPH oxidase by a VAV1, Rac1, and PAK1 signaling axis. J Biol Chem (2007) 1.02
Alpha-1-antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis. Eur J Haematol (2011) 1.02
Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent. Mol Cancer Res (2008) 1.00
Internalization mechanisms of the epidermal growth factor receptor after activation with different ligands. PLoS One (2013) 0.99
Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP). J Biol Chem (2003) 0.96
Dysregulation of Ack1 inhibits down-regulation of the EGF receptor. Exp Cell Res (2008) 0.95
Differential roles of Grb2 and AP-2 in p38 MAPK- and EGF-induced EGFR internalization. Traffic (2012) 0.95
"Nonclassical" secretion of annexin A2 to the lumenal side of the enterocyte brush border membrane. Biochemistry (2003) 0.95
Expression of epidermal growth factor receptor or ErbB3 facilitates geldanamycin-induced down-regulation of ErbB2. Mol Cancer Res (2009) 0.94
Interplay between toxin transport and flotillin localization. PLoS One (2010) 0.94
Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor. Exp Cell Res (2006) 0.92
A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner. Traffic (2011) 0.91
Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells. Eur J Cell Biol (2007) 0.91
Sarcolemmal FAT/CD36 in human skeletal muscle colocalizes with caveolin-3 and is more abundant in type 1 than in type 2 fibers. J Lipid Res (2004) 0.90
The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis. Exp Cell Res (2007) 0.87
EGFR signaling patterns are regulated by its different ligands. Growth Factors (2014) 0.86
EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells. Cell Signal (2011) 0.86
Difference in TB10.4 T-cell epitope recognition following immunization with recombinant TB10.4, BCG or infection with Mycobacterium tuberculosis. Eur J Immunol (2010) 0.85
CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor. Exp Cell Res (2011) 0.85
Nimotuzumab and cetuximab block ligand-independent EGF receptor signaling efficiently at different concentrations. J Immunother (2011) 0.84
Preubiquitinated chimeric ErbB2 is constitutively endocytosed and subsequently degraded in lysosomes. Exp Cell Res (2012) 0.84
Cetuximab in combination with anti-human IgG antibodies efficiently down-regulates the EGF receptor by macropinocytosis. Exp Cell Res (2012) 0.84
Shiga toxin increases formation of clathrin-coated pits through Syk kinase. PLoS One (2010) 0.83
Regulation of plasma long-chain fatty acid oxidation in relation to uptake in human skeletal muscle during exercise. Am J Physiol Endocrinol Metab (2004) 0.82
The oncoprotein ErbB3 is endocytosed in the absence of added ligand in a clathrin-dependent manner. Carcinogenesis (2012) 0.82
Detection of food-derived damaged nucleosides with possible adverse effects on human health using a global adductomics approach. J Agric Food Chem (2010) 0.82
Cell-surface metalloprotease ADAM12 is internalized by a clathrin- and Grb2-dependent mechanism. Traffic (2012) 0.81
Decorin accumulation contributes to the stromal opacities found in congenital stromal corneal dystrophy. Invest Ophthalmol Vis Sci (2010) 0.81
NADPH oxidase is internalized by clathrin-coated pits and localizes to a Rab27A/B GTPase-regulated secretory compartment in activated macrophages. J Biol Chem (2011) 0.81
Pertuzumab Increases 17-AAG-Induced Degradation of ErbB2, and This Effect Is Further Increased by Combining Pertuzumab with Trastuzumab. Pharmaceuticals (Basel) (2012) 0.81
CD7 expression by CD34+ cells in CML patients, of prognostic significance? Eur J Haematol (2003) 0.80
Zebrafish ( Danio rerio) as a model for investigating the safety of GM feed ingredients (soya and maize); performance, stress response and uptake of dietary DNA sequences. Br J Nutr (2009) 0.79
Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies. PLoS One (2012) 0.79
Pertuzumab counteracts the inhibitory effect of ErbB2 on degradation of ErbB3. Carcinogenesis (2013) 0.79
Mutants of the protein serine kinase PSKH1 disassemble the Golgi apparatus. Exp Cell Res (2003) 0.78
Factor XII binding to endothelial cells depends on caveolae. Eur J Biochem (2004) 0.78
Cell biology: Viruses in camouflage. Nature (2008) 0.75