Robert V Stahelin

Author PubWeight™ 51.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Membrane-protein interactions in cell signaling and membrane trafficking. Annu Rev Biophys Biomol Struct 2005 3.97
2 Membrane binding and subcellular targeting of C2 domains. Biochim Biophys Acta 2006 2.20
3 Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction. EMBO J 2002 2.09
4 Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis. EMBO Mol Med 2012 1.68
5 Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains. J Biol Chem 2003 1.39
6 Ceramide 1-phosphate acts as a positive allosteric activator of group IVA cytosolic phospholipase A2 alpha and enhances the interaction of the enzyme with phosphatidylcholine. J Biol Chem 2005 1.30
7 Endoplasmic reticulum PI(3)P lipid binding targets malaria proteins to the host cell. Cell 2012 1.26
8 Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain. J Biol Chem 2008 1.26
9 The molecular basis of the differential subcellular localization of FYVE domains. J Biol Chem 2004 1.23
10 Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain. J Biol Chem 2011 1.21
11 Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Ctheta. J Biol Chem 2007 1.18
12 Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis. J Lipid Res 2007 1.14
13 Investigation of Ebola VP40 assembly and oligomerization in live cells using number and brightness analysis. Biophys J 2012 1.14
14 Molecular mechanism of membrane docking by the Vam7p PX domain. J Biol Chem 2006 1.12
15 Computer modeling of the membrane interaction of FYVE domains. J Mol Biol 2003 1.12
16 Structural bioinformatics prediction of membrane-binding proteins. J Mol Biol 2006 1.12
17 pH-dependent binding of the Epsin ENTH domain and the AP180 ANTH domain to PI(4,5)P2-containing bilayers. J Mol Biol 2007 1.11
18 X-ray reflectivity studies of cPLA2{alpha}-C2 domains adsorbed onto Langmuir monolayers of SOPC. Biophys J 2005 1.11
19 Ceramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis. J Biol Chem 2009 1.10
20 Molecular mechanism of membrane targeting by the GRP1 PH domain. J Lipid Res 2008 1.09
21 The Ebola virus matrix protein penetrates into the plasma membrane: a key step in viral protein 40 (VP40) oligomerization and viral egress. J Biol Chem 2013 1.07
22 Biophysical and computational studies of membrane penetration by the GRP1 pleckstrin homology domain. Structure 2011 1.05
23 Selection of DNA ligands for protein kinase C-delta. Chem Commun (Camb) 2006 1.04
24 Anionic lipids activate group IVA cytosolic phospholipase A2 via distinct and separate mechanisms. J Lipid Res 2007 1.04
25 Membrane insertion of the FYVE domain is modulated by pH. Proteins 2009 1.01
26 Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain. J Biol Chem 2010 1.00
27 The Ebola virus matrix protein deeply penetrates the plasma membrane: an important step in viral egress. Biophys J 2013 0.99
28 MeTaDoR: a comprehensive resource for membrane targeting domains and their host proteins. Bioinformatics 2007 0.95
29 Emerging methodologies to investigate lipid-protein interactions. Integr Biol (Camb) 2012 0.92
30 Ceramide kinase regulates the production of tumor necrosis factor α (TNFα) via inhibition of TNFα-converting enzyme. J Biol Chem 2011 0.91
31 p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation. J Biol Chem 2010 0.90
32 Noncovalent keystone interactions controlling biomembrane structure. Chemistry 2008 0.88
33 Orientation and penetration depth of monolayer-bound p40phox-PX. Biochemistry 2006 0.88
34 Single-particle tracking demonstrates that actin coordinates the movement of the Ebola virus matrix protein. Biophys J 2012 0.85
35 PI(3)P-independent and -dependent pathways function together in a vacuolar translocation sequence to target malarial proteins to the host erythrocyte. Mol Biochem Parasitol 2012 0.84
36 Modular synthesis of biologically active phosphatidic acid probes using click chemistry. Mol Biosyst 2009 0.84
37 Genome-wide structural analysis reveals novel membrane binding properties of AP180 N-terminal homology (ANTH) domains. J Biol Chem 2011 0.83
38 C2 domain membrane penetration by group IVA cytosolic phospholipase A₂ induces membrane curvature changes. J Lipid Res 2012 0.81
39 The molecular basis of ceramide-1-phosphate recognition by C2 domains. J Lipid Res 2012 0.81
40 Host targeting of virulence determinants and phosphoinositides in blood stage malaria parasites. Trends Parasitol 2012 0.79
41 Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complex. J Biol Chem 2013 0.79
42 Synthesis and convenient functionalization of azide-labeled diacylglycerol analogues for modular access to biologically active lipid probes. Bioconjug Chem 2008 0.79
43 Metabolically stabilized derivatives of phosphatidylinositol 4-phosphate: synthesis and applications. Chem Biol 2011 0.77
44 Eukaryotic virulence determinants utilize phosphoinositides at the ER and host cell surface. Trends Microbiol 2013 0.77
45 Peripheral proteins as drug targets. Curr Drug Targets 2008 0.76
46 Bacterial expression and purification of C1 and C2 domains of protein kinase C isoforms. Methods Mol Biol 2003 0.76
47 Conformational Flexibility of the Protein-Protein Interfaces of the Ebola Virus VP40 Structural Matrix Filament. J Phys Chem B 2019 0.75