Published in Biotechniques on September 01, 2006
Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation. Nucleic Acids Res (2007) 2.69
A new approach to primer design for the control of PCR bias in methylation studies. BMC Res Notes (2008) 1.42
Correction of PCR-bias in quantitative DNA methylation studies by means of cubic polynomial regression. Nucleic Acids Res (2011) 1.08
Quality assessment of DNA derived from up to 30 years old formalin fixed paraffin embedded (FFPE) tissue for PCR-based methylation analysis using SMART-MSP and MS-HRM. BMC Cancer (2009) 1.06
Beckwith-Wiedemann syndrome and uniparental disomy 11p: fine mapping of the recombination breakpoints and evaluation of several techniques. Eur J Hum Genet (2011) 0.95
Sensitive quantitative analysis of murine LINE1 DNA methylation using high resolution melt analysis. Epigenetics (2012) 0.95
Quantification of epigenetic biomarkers: an evaluation of established and emerging methods for DNA methylation analysis. BMC Genomics (2014) 0.87
A closed-tube methylation-sensitive high resolution melting assay (MS-HRMA) for the semi-quantitative determination of CST6 promoter methylation in clinical samples. BMC Cancer (2012) 0.84
A refined, rapid and reproducible high resolution melt (HRM)-based method suitable for quantification of global LINE-1 repetitive element methylation. BMC Res Notes (2011) 0.84
Semi-quantitative detection of GADD45-gamma methylation levels in gastric, colorectal and pancreatic cancers using methylation-sensitive high-resolution melting analysis. J Cancer Res Clin Oncol (2010) 0.79
Constitutional MLH1 methylation presenting with colonic polyposis syndrome and not Lynch syndrome. Fam Cancer (2016) 0.77
Evaluation of Different Oligonucleotide Base Substitutions at CpG Binding sites in Multiplex Bisulfite-PCR sequencing. Sci Rep (2017) 0.75
Assessing alternative base substitutions at primer CpG sites to optimise unbiased PCR amplification of methylated sequences. Clin Epigenetics (2017) 0.75
Reference Materials for Calibration of Analytical Biases in Quantification of DNA Methylation. PLoS One (2015) 0.75
Familial cancer associated with a polymorphism in ARLTS1. N Engl J Med (2005) 3.35
Evaluation of BRAF mutation testing methodologies in formalin-fixed, paraffin-embedded cutaneous melanomas. J Mol Diagn (2012) 2.53
Methylation-sensitive high-resolution melting. Nat Protoc (2008) 1.80
Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas. Int J Cancer (2011) 1.65
Epigenetics and cancer treatment. Eur J Pharmacol (2009) 1.64
PCR-based methods for detecting single-locus DNA methylation biomarkers in cancer diagnostics, prognostics, and response to treatment. Clin Chem (2009) 1.49
Comprehensive genome methylation analysis in bladder cancer: identification and validation of novel methylated genes and application of these as urinary tumor markers. Clin Cancer Res (2011) 1.46
Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis. J Cell Sci (2008) 1.46
A new approach to primer design for the control of PCR bias in methylation studies. BMC Res Notes (2008) 1.42
Primer design versus PCR bias in methylation independent PCR amplifications. Epigenetics (2009) 1.18
Increased sensitivity of KRAS mutation detection by high-resolution melting analysis of COLD-PCR products. Hum Mutat (2010) 1.12
The challenges of comparing a clinically validated test to other methods. J Mol Diagn (2013) 1.09
Identification of accurate reference genes for RT-qPCR analysis of formalin-fixed paraffin-embedded tissue from primary non-small cell lung cancers and brain and lymph node metastases. Lung Cancer (2013) 1.07
Quality assessment of DNA derived from up to 30 years old formalin fixed paraffin embedded (FFPE) tissue for PCR-based methylation analysis using SMART-MSP and MS-HRM. BMC Cancer (2009) 1.06
Germline mutation in RNASEL predicts increased risk of head and neck, uterine cervix and breast cancer. PLoS One (2008) 1.04
Methylation of MGMT in malignant pleural mesothelioma occurs in a subset of patients and is associated with the T allele of the rs16906252 MGMT promoter SNP. Lung Cancer (2010) 0.95
Competitive amplification of differentially melting amplicons (CADMA) improves KRAS hotspot mutation testing in colorectal cancer. BMC Cancer (2012) 0.95
Investigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing. Sci Rep (2013) 0.94
A fragile site within the HPC1 region at 1q25.3 affecting RGS16, RGSL1, and RGSL2 in human breast carcinomas. Genes Chromosomes Cancer (2008) 0.93
Limitations and advantages of MS-HRM and bisulfite sequencing for single locus methylation studies. Expert Rev Mol Diagn (2010) 0.90
Competitive amplification of differentially melting amplicons (CADMA) enables sensitive and direct detection of all mutation types by high-resolution melting analysis. Hum Mutat (2011) 0.89
Methods and biomarkers for the diagnosis and prognosis of cancer and other diseases: towards personalized medicine. Drug Resist Updat (2006) 0.89
Methylation of cancer related genes in tumor and peripheral blood DNA from the same breast cancer patient as two independent events. Diagn Pathol (2011) 0.89
Genotyping common FSHR polymorphisms based on competitive amplification of differentially melting amplicons (CADMA). J Assist Reprod Genet (2014) 0.84
The effect of genetic variability on drug response in conventional breast cancer treatment. Eur J Pharmacol (2009) 0.84
Techniques used in studies of age-related DNA methylation changes. Ann N Y Acad Sci (2006) 0.83
LOH rather than genotypes of TP53 codon 72 is associated with disease-free survival in primary breast cancer. Acta Oncol (2006) 0.81
High-resolution melting analysis for mutation screening of RGSL1, RGS16, and RGS8 in breast cancer. Cancer Epidemiol Biomarkers Prev (2010) 0.81
Frequent LOH at hMLH1, a highly variable SNP in hMSH3, and negligible coding instability in ovarian cancer. Anticancer Res (2002) 0.79
ELMO3: a direct driver of cancer metastasis? Cell Cycle (2014) 0.78
A simple way to evaluate self-designed probes for tumor specific Multiplex Ligation-dependent Probe Amplification (MLPA). BMC Res Notes (2010) 0.77
Deconstructing PTI-1: PTI-1 is a truncated, but not mutated, form of translation elongatin factor 1A1, eEF1A1. Biochim Biophys Acta (2005) 0.77
A role for immunohistochemical detection of BRAF V600E prior to BRAF-inhibitor treatment of malignant melanoma? J Clin Pathol (2013) 0.77
Author's reply: To PMID 23159593. J Mol Diagn (2013) 0.75
Chromosome 1q25.3 copy number alterations in primary breast cancers detected by multiplex ligation-dependent probe amplification and allelic imbalance assays and its comparison with fluorescent in situ hybridization assays. Cell Oncol (Dordr) (2012) 0.75
A nine-nucleotide deletion and splice variation in the coding region of the interferon induced ISG12 gene. Biochim Biophys Acta (2003) 0.75