S J Meltzer

Author PubWeight™ 198.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 EXPERIMENTAL PNEUMONIA BY INTRABRONCHIAL INSUFFLATION. J Exp Med 1912 31.80
2 A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998 20.08
3 EXPERIMENTAL BRONCHOPNEUMONIA BY INTRABRONCHIAL INSUFFLATION. J Exp Med 1912 8.95
4 PNEUMONIC LESIONS MADE BY INTRABRONCHIAL INSUFFLATION OF NON-VIRULENT PNEUMOCOCCI. J Exp Med 1913 5.14
5 Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer. Cancer Res 2000 2.99
6 EXPERIMENTAL CONTRIBUTION TO THE STUDY OF THE PATH BY WHICH FLUIDS ARE CARRIED FROM THE PERITONEAL CAVITY INTO THE CIRULATION. J Exp Med 1896 2.94
7 Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus. Am J Pathol 1999 2.88
8 6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity. Ann Intern Med 1989 2.70
9 THE REACTION OF THE LUNGS TO THE INTRABRONCHIAL INSUFFLATION OF KILLED VIRULENT PNEUMOCOCCI AND OF PLAIN STERILE BOUILLON. J Exp Med 1913 2.53
10 PTEN1 is frequently mutated in primary endometrial carcinomas. Nat Genet 1997 2.44
11 Human papillomavirus DNA sequences in esophagus squamous cell carcinoma. Gastroenterology 1994 2.20
12 Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nat Genet 1996 2.19
13 PNEUMONIC LESIONS CAUSED BY BACILLUS MEGATHERIUM. J Exp Med 1913 2.10
14 Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability. Cancer Res 1999 2.09
15 E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas. J Natl Cancer Inst 2000 2.05
16 Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis. Gastroenterology 1999 2.04
17 Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways. J Clin Pathol 1999 1.98
18 Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas. Cancer Res 1998 1.94
19 On the Respiratory Changes of the Intrathoracic Pressure, measured in the Mediastinum Posterior. J Physiol 1892 1.89
20 Loss of heterozygosity involves multiple tumor suppressor genes in human esophageal cancers. Cancer Res 1992 1.65
21 Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia. Oncogene 2000 1.63
22 Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers. Proc Natl Acad Sci U S A 1992 1.56
23 Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis. Oncogene 2006 1.55
24 Global gene expression profiling in Barrett's esophagus and esophageal cancer: a comparative analysis using cDNA microarrays. Oncogene 2002 1.54
25 17p allelic losses in diploid cells of patients with Barrett's esophagus who develop aneuploidy. Cancer Res 1994 1.52
26 Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability. Cancer Res 2001 1.52
27 Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma. J Natl Cancer Inst 2000 1.45
28 Retention in the Circulation of Dextrose in Normal and Depancreatized Animals, and the Effect of an Intravenous Injection of an Emulsion of Pancreas Upon This Retention. Proc Natl Acad Sci U S A 1915 1.45
29 A transforming growth factor beta 1 receptor type II mutation in ulcerative colitis-associated neoplasms. Gastroenterology 1997 1.42
30 Clonal ordering of 17p and 5q allelic losses in Barrett dysplasia and adenocarcinoma. Proc Natl Acad Sci U S A 1993 1.40
31 THE RELATION OF THE RATE OF ABSORPTION OF ADRENALIN TO ITS GLYCOSURIC AND DIURETIC EFFECTS. J Exp Med 1913 1.40
32 Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells. Cancer Res 2001 1.39
33 Growth suppression of esophageal cancer cells by p16INK4 and p15INK4B in vitro. Cancer J Sci Am 2006 1.39
34 AN EXPERIMENTAL STUDY OF THE ADDITIVE AND ANTAGONISTIC ACTIONS OF SODIUM OXALATE, AND SALTS OF MAGNESIUM AND CALCIUM IN THE RABBIT. J Exp Med 1916 1.38
35 The Dynamics of Living Matter. Science 1906 1.37
36 p53 point mutations in dysplastic and cancerous ulcerative colitis lesions. Gastroenterology 1993 1.36
37 Appendiceal obstruction by a toothpick removed at colonoscopy. Am J Gastroenterol 1986 1.33
38 Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line. Gastroenterology 1996 1.33
39 Adenomatous polyposis coli gene mutations in ulcerative colitis-associated dysplasias and cancers versus sporadic colon neoplasms. Cancer Res 1995 1.31
40 Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma. Oncogene 2007 1.31
41 EXPERIMENTAL CHEMICAL PNEUMONIA. J Exp Med 1918 1.31
42 Glypican-3 expression in Wilms tumor and hepatoblastoma. J Pediatr Hematol Oncol 2001 1.30
43 ABC of colorectal cancer. Molecular basis for risk factors. BMJ 2000 1.30
44 MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro. Oncogene 2010 1.25
45 Microsatellite instability occurs frequently in human gastric carcinoma. Oncogene 1994 1.21
46 Microsatellite instability in ulcerative colitis-associated colorectal dysplasias and cancers. Cancer Res 1994 1.20
47 Polymorphic sites within the MCC and APC loci reveal very frequent loss of heterozygosity in human small cell lung cancer. Cancer Res 1992 1.18
48 Allelotype analysis of oesophageal adenocarcinoma: loss of heterozygosity occurs at multiple sites. Br J Cancer 1998 1.18
49 Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia. Oncogene 2001 1.17
50 Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival. Oncogene 2001 1.17
51 APC gene mutations in the mutation cluster region are rare in esophageal cancers. Gastroenterology 1994 1.14
52 p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2. Cancer Res 2001 1.11
53 Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1. Cancer Res 2000 1.10
54 Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors. Cancer Res 1997 1.09
55 The insulin-like growth factor II receptor gene is mutated in genetically unstable cancers of the endometrium, stomach, and colorectum. Cancer Res 1997 1.09
56 Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability. Oncogene 1999 1.08
57 Protooncogene abnormalities in colon cancers and adenomatous polyps. Gastroenterology 1987 1.07
58 Loss of heterozygosity affecting the p53, Rb, and mcc/apc tumor suppressor gene loci in dysplastic and cancerous ulcerative colitis. Cancer Res 1992 1.07
59 Following in mother's footsteps? Mother-daughter risks for insulin resistance and cardiovascular disease 15 years after gestational diabetes. Diabet Med 2010 1.05
60 Altered messenger RNA and unique mutational profiles of p53 and Rb in human esophageal carcinomas. Cancer Res 1993 1.05
61 Human cyclin D1 oncogene and esophageal squamous cell carcinoma. Cancer 1995 1.04
62 Infrequent DPC4 gene mutation in esophageal cancer, gastric cancer and ulcerative colitis-associated neoplasms. Oncogene 1996 1.03
63 Frequent loss of heterozygosity at the retinoblastoma locus in human esophageal cancers. Cancer Res 1991 0.99
64 p53 protein expression in ulcerative colitis-associated colorectal dysplasia and carcinoma. Hum Pathol 1994 0.99
65 Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers. Oncogene 1998 0.97
66 Loss of transforming growth factor-beta type II receptor gene expression in primary human esophageal cancer. Lab Invest 1996 0.97
67 The MTS1 gene is frequently mutated in primary human esophageal tumors. Oncogene 1994 0.96
68 EFFECT OF INTRABRONCHIAL INSUFFLATION OF SOLUTIONS OF SOME INORGANIC SALTS. J Exp Med 1918 0.95
69 THE DEPLORABLE CONTRAST BETWEEN INTRANATIONAL AND INTERNATIONAL ETHICS AND THE MISSION OF MEDICAL SCIENCE AND MEDICAL MEN. Science 1915 0.94
70 Recurrent pancreatitis caused by vegetable matter obstruction. Am J Gastroenterol 1986 0.94
71 Alterations of transforming growth factor-beta 1 receptor type II occur in ulcerative colitis-associated carcinomas, sporadic colorectal neoplasms, and esophageal carcinomas, but not in gastric neoplasms. Hum Cell 1996 0.94
72 The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract. Oncogene 1999 0.94
73 Kaposi's sarcoma occurring in association with ulcerative colitis. Am J Gastroenterol 1987 0.92
74 The MspI polymorphism in intron 6 of p53 (TP53) detected by digestion of PCR products. Nucleic Acids Res 1991 0.92
75 FHIT gene alterations in esophageal cancer and ulcerative colitis (UC). Oncogene 1997 0.91
76 Nature and course of pancreatitis caused by 6-mercaptopurine in the treatment of inflammatory bowel disease. Gastroenterology 1986 0.91
77 Allelic deletions of MCC/APC and p53 are frequent late events in human gastric carcinogenesis. Gastroenterology 1994 0.90
78 Frequent loss of heterozygosity on chromosome 9 in adenocarcinoma and squamous cell carcinoma of the esophagus. Cancer Res 1994 0.90
79 Esophagin cDNA cloning and characterization: a tissue-specific member of the small proline-rich protein family that is not expressed in esophageal tumors. Cell Growth Differ 1996 0.89
80 THE CHARACTER OF THE PNEUMONIC LESIONS PRODUCED BY INTRABRONCHIAL INSUFFLATION OF VIRULENT STREPTOCOCCI. J Exp Med 1913 0.89
81 The molecular basis for carcinogenesis in metaplastic columnar-lined esophagus. Gastroenterol Clin North Am 1997 0.89
82 Deficient transforming growth factor-beta1 activation and excessive insulin-like growth factor II (IGFII) expression in IGFII receptor-mutant tumors. Cancer Res 1997 0.89
83 Explant organ culture: a review. Cytotechnology 1991 0.88
84 Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues. Cancer Res 1998 0.88
85 Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas. Hum Mutat 1997 0.87
86 Loss of heterozygosity of p53 in oral cancers demonstrated by the polymerase chain reaction. Cancer 1993 0.87
87 Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells. Oncogene 1999 0.87
88 Anti-p53 antibodies in patients with Barrett's esophagus or esophageal carcinoma can predate cancer diagnosis. Gastroenterology 1998 0.86
89 Genomic DNA and messenger RNA expression alterations of the CDKN2B and CDKN2 genes in esophageal squamous carcinoma cell lines. Genes Chromosomes Cancer 1995 0.85
90 On the Paths of Absorption from the Peritoneal Cavity. J Physiol 1897 0.84
91 P53 gene protein overexpression predicts results of trimodality therapy in esophageal cancer patients. Ann Thorac Surg 1999 0.83
92 Loss of heterozygosity involving the APC gene in oral squamous cell carcinomas. Oral Surg Oral Med Oral Pathol 1994 0.83
93 Activation of a cryptic splice site of PTEN and loss of heterozygosity in benign skin lesions in Cowden disease. J Invest Dermatol 2001 0.82
94 Colon carcinogenesis in inflammatory bowel disease. Inflamm Bowel Dis 1995 0.82
95 The Behaviour of the Red Blood-corpuscles when shaken with Indifferent Substances. J Physiol 1885 0.81
96 Thyroid disease with monoclonal (immunoglobulin G lambda) antibody to triiodothyronine and thyroxine. J Clin Endocrinol Metab 1983 0.80
97 Rodent cell transformation and immediate early gene expression following 60-Hz magnetic field exposure. Environ Health Perspect 1996 0.79
98 p53 mutational status and survival of human breast cancer MCF-7 cell variants after exposure to X rays or fission neutrons. Radiat Res 1995 0.79
99 Multiple target sites of allelic imbalance on chromosome 17 in Barrett's oesophageal cancer. Oncogene 1999 0.79
100 A unique p53 intragenic deletion flanked by short direct repeats results in loss of mRNA expression in a human esophageal carcinoma. Carcinogenesis 1994 0.79
101 Tumor genomics vs. tumor genetics: a paradigm shift? Gastroenterology 2001 0.79
102 Dr. Strange DNA, or how I learned to stop cloning and love the computer. Gastroenterology 1995 0.78
103 THE POSTMORTEM RIGOR OF THE MAMMALIAN HEART AND THE INFLUENCE OF AN ANTEMORTEM STIMULATION OF THE PNEUMOGASTRIC NERVES UPON ITS DEVELOPMENT. J Exp Med 1909 0.78
104 RAS gene activation in acute myelogenous leukemia: analysis by in vitro amplification and DNA base sequence determination. Genes Chromosomes Cancer 1990 0.78
105 HEADSHIP AND ORGANIZATION OF CLINICAL DEPARTMENTS OF FIRST-CLASS MEDICAL SCHOOLS. Science 1914 0.77
106 THE FACTORS OF SAFETY IN ANIMAL STRUCTURE AND ANIMAL ECONOMY. Science 1907 0.77
107 New guidelines for the management of diabetes: a physician's guide. Steering Committee for the Revision of the Clinical Practice Guidelines for the Management of Diabetes in Canada. CMAJ 1998 0.77
108 Csa-19, a radiation-responsive human gene, identified by an unbiased two-gel cDNA library screening method in human cancer cells. Oncogene 1997 0.77
109 On a Difference in the Influence upon Inflammation between the Section of the Sympathetic Nerve and the Removal of the sympathetic Ganglion. J Med Res 1903 0.76
110 The apoptotic regulatory gene, BCL10, is mutated in sporadic mismatch repair deficient colorectal cancers. Cell Death Differ 2000 0.76
111 Low prevalence of the APC I1307K sequence in Jewish and non-Jewish patients with inflammatory bowel disease. Oncogene 1999 0.76
112 E2F-4 mutation in hereditary non-polyposis colorectal cancer. J Exp Clin Cancer Res 2002 0.76
113 Apparent protection from instability of repeat sequences in cancer-related genes in replication error positive gastrointestinal cancers. Oncogene 1997 0.75
114 THE EFFECT OF PAINTING THE PANCREAS WITH ADRENALIN UPON HYPERGLYCEMIA AND GLYCOSURIA. J Exp Med 1918 0.75
115 EMIL DU BOIS-REYMOND. Science 1897 0.75
116 THE INTRAVENOUS INJECTION OF MAGNESIUM SULPHATE FOR ANESTHESIA IN ANIMALS. J Exp Med 1916 0.75
117 Cytogenetic studies of primary cultures of esophageal squamous cell carcinoma. Cancer Genet Cytogenet 1993 0.75
118 THE DOMAIN OF PHYSIOLOGY AND ITS RELATIONS TO MEDICINE. Science 1904 0.75
119 BIGEL analysis of gene expression in HL60 cells exposed to X rays or 60 Hz magnetic fields. Radiat Res 1998 0.75
120 c-myc amplification coexistent with activating N-ras point mutation in the biphenotypic leukemic cell line RED-3. Leukemia 1989 0.75
121 Direct radioactive labeling of unpurified PCR products using Klenow fragment. Biotechniques 1991 0.75
122 Direct radioactive labeling of polymerase chain reaction products. Methods Mol Biol 1993 0.75
123 Microsatellite instability is infrequent in neuroblastoma. Cancer Epidemiol Biomarkers Prev 1995 0.75
124 Microsatellite Analysis of the Insulin-Like Growth Factor II Receptor in Colorectal Carcinomas. Methods Mol Med 2001 0.75
125 Historical profiles. Our aims. S. J. Meltzer. Presidential address. Gastroenterology 1979 0.75
126 AN EXPERIMENTAL STUDY OF THE QUESTION OF ASPIRATION OF FOREIGN MATERIAL INTO THE AIR PASSAGES DURING INTRATRACHEAL INSUFFLATION. J Exp Med 1911 0.75
127 ON ABSORPTION FROM INTRAMUSCULAR TISSUE. J Exp Med 1911 0.75
128 FRATERNITAS MEDICORUM; A REPORT AND A DISCUSSION. Science 1916 0.75
129 THE STATUS OF RESPIRATION IN THE METHODS OF DIFFERENTIAL PRESSURE COMPARED WITH THAT UNDER THE METHOD OF INTRATRACHEAL INSUFFLATION. J Exp Med 1911 0.75
130 On the Clotting of Blood of nephrectomized Rabbits. J Med Res 1904 0.75
131 Frontiers in gastroenterology: new clinical and research opportunities. Md Med J 1991 0.75
132 A PROTEST. Science 1908 0.75
133 THE POSTMORTEM RIGOR OF THE MAMMALIAN HEART AND THE INFLUENCE OF AN ANTEMORTEM STIMULATION OF THE PNEUMOGASTRIC NERVES UPON ITS DEVELOPMENT. J Exp Med 1909 0.75
134 Direct radioactive labeling of polymerase chain reaction products. Methods Mol Biol 1996 0.75
135 PROFESSOR HUGO KRONECKER. Science 1914 0.75
136 The Influence of Morphin Upon the Elimination of Intravenously Injected Dextrose in Dogs. Proc Natl Acad Sci U S A 1916 0.75
137 Effect of naturally occurring E2F-4 alterations on transcriptional activation and proliferation in transfected cells. Lab Invest 2001 0.75
138 THE NEEDS OF MEN OF SCIENCE IN RUMANIA. Science 1920 0.75
139 The Influence of Nephrectomy upon Absorption - an Experimental Study from the Rockefeller Institute for Medical Research. J Med Res 1903 0.75
140 AN EXPERIMENTAL STUDY OF THE DIRECT INOCULATION OF BACTERIA INTO THE SPLEEN OF LIVING ANIMALS; AND A CONTRIBUTION TO THE KNOWLEDGE OF THE IMPORTANCE OF A LESION IN ANIMAL TISSUE FOR THE LODGMENT AND MULTIPLICATION OF BACTERIA WITHIN IT. J Exp Med 1898 0.75
141 Colon polyps in Beckwith-Wiedmann syndrome: role of imprinted genes. Gastroenterology 2000 0.75
142 Experiments relating to the Question of Fixation of Strychnine in Animal Tissues. J Med Res 1903 0.75