Published in J Physiol on July 07, 1927
Fatigue of the sense organs in muscle. J Physiol (1929) 10.11
The effect of frequency of excitation on the total electric response of medullated nerve. J Physiol (1935) 7.58
Studies on nerve metabolism: I. The influence of oxygen lack on heat production and action current. J Physiol (1927) 6.29
The electric response of nerve to two stimuli. J Physiol (1929) 1.34
Characteristics required in electrical pulses for stimulation of the respiration of separated mammalian cerebral tissues. J Physiol (1954) 1.13
The relative importance of the blood supply and the continuity of the axon in recovery after prolonged stimulation of mammalian nerve. J Physiol (1953) 1.12
The effect of frequency of excitation on the thermal response of medullated nerve. J Physiol (1935) 1.00
Note on the electric response of nerve to two stimuli. J Physiol (1928) 0.99
Cerebral glycolysis: a century of persistent misunderstanding and misconception. Front Neurosci (2014) 0.84
The supernormal phase in muscular contraction. J Physiol (1932) 0.75
The nature of the isometric twitch. J Physiol (1921) 30.00
The impulses produced by sensory nerve endings: Part 3. Impulses set up by Touch and Pressure. J Physiol (1926) 58.76
The impulses produced by sensory nerve-endings: Part II. The response of a Single End-Organ. J Physiol (1926) 40.20
The nature of the isometric twitch. J Physiol (1921) 30.00
A new mathematical treatment of changes of ionic concentration in muscle and nerve under the action of electric currents, with a theory as to their mode of excitation. J Physiol (1910) 23.56
The heat-production in prolonged contractions of an isolated frog's muscle. J Physiol (1913) 23.23
The regulation of the supply of energy in muscular contraction. J Physiol (1921) 22.57
Length of muscle, and the heat and tension developed in an isometric contraction. J Physiol (1925) 19.20
The recovery heat-production in muscle. J Physiol (1922) 19.13
The two phases of heat production of nerve. J Physiol (1927) 18.68
The four phases of heat-production of muscle. J Physiol (1920) 18.40
Repetitive stimulation by commutator and condenser. J Physiol (1934) 15.17
The absolute mechanical efficiency of the contraction of an isolated muscle. J Physiol (1913) 14.19
Touch, pain and tickling: an electro-physiological investigation on cutaneous sensory nerves. J Physiol (1939) 13.11
The relation of length to tension development and heat production on contraction in muscle. J Physiol (1914) 11.40
The anaerobic processes involved in muscular activity. J Physiol (1923) 11.31
The nature of oxyhaemoglobin, with a note on its molecular weight. J Physiol (1910) 10.05
Studies on nerve metabolism: Carbohydrate metabolism of resting mammalian nerve. Biochem J (1929) 9.14
A new form of differential micro-calorimeter, for the estimation of heat production in physiological, bacteriological, or ferment actions. J Physiol (1911) 8.14
The effect of frequency of excitation on the total electric response of medullated nerve. J Physiol (1935) 7.58
The effect of hydrogen-ion concentration on the recovery process in muscle. J Physiol (1924) 7.30
Rapid effector function in CD8+ memory T cells. J Exp Med (1997) 6.36
TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. Lancet (1990) 6.32
Studies on nerve metabolism: I. The influence of oxygen lack on heat production and action current. J Physiol (1927) 6.29
Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans. N Engl J Med (1998) 6.14
On the hydrogen-ion concentration and some related properties of normal human blood. J Physiol (1922) 5.20
Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells. Am J Respir Crit Care Med (2001) 5.06
Evolutionary relationships of human populations from an analysis of nuclear DNA polymorphisms. Nature (1986) 4.84
The mode of action of nicotine and curari, determined by the form of the contraction curve and the method of temperature coefficients. J Physiol (1909) 4.81
Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodies. Lancet (1990) 4.58
The maximum work and mechanical efficiency of human muscles, and their most economical speed. J Physiol (1922) 4.39
Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature (1994) 4.37
The heat production of muscles treated with caffein or subjected to prolonged discontinuous stimulation. J Physiol (1924) 4.33
Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara. Nat Med (1998) 4.13
Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment. J Immunol (2001) 3.79
Electric excitation of the fin nerve of sepia. J Physiol (1935) 3.76
Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (1998) 3.59
Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians. J Infect Dis (2000) 3.58
Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia. N Engl J Med (1995) 3.54
Association of malaria parasite population structure, HLA, and immunological antagonism. Science (1998) 3.40
Vascular reactions of the skin to injury: Part VIII. The resistance of the human skin to constant currents, in relation to injury and vascular response. J Physiol (1927) 3.35
The microphonic effect of teleost labyrinths and its biological significance. J Physiol (1943) 3.34
Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells. Lancet (2001) 3.15
In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope. Nat Med (2000) 3.04
A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. Nat Genet (1999) 2.83
Genetics of susceptibility to human infectious disease. Nat Rev Genet (2001) 2.80
Tuberculosis and chronic hepatitis B virus infection in Africans and variation in the vitamin D receptor gene. J Infect Dis (1999) 2.79
mtDNA control-region sequence variation suggests multiple independent origins of an "Asian-specific" 9-bp deletion in sub-Saharan Africans. Am J Hum Genet (1996) 2.79
High frequencies of alpha-thalassaemia are the result of natural selection by malaria. Nature (1986) 2.68
Genetic susceptibility to tuberculosis in Africans: a genome-wide scan. Proc Natl Acad Sci U S A (2000) 2.44
The Specific Electrical Resistance of Frog's Muscle. Biochem J (1921) 2.44
Enhanced immunogenicity of CD4(+) t-cell responses and protective efficacy of a DNA-modified vaccinia virus Ankara prime-boost vaccination regimen for murine tuberculosis. Infect Immun (2001) 2.31
Direct cloning of specific genomic DNA sequences in plasmid libraries following fragment enrichment. Nucleic Acids Res (1985) 2.27
Analysis of the human alpha-globin gene cluster reveals a highly informative genetic locus. Proc Natl Acad Sci U S A (1986) 2.26
Vaccines against intracellular infections requiring cellular immunity. Nature (2000) 2.20
The heat-production and the mechanism of the veratrine contraction. J Physiol (1922) 2.11
High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene. Hum Mol Genet (1992) 2.09
Malaria susceptibility and CD36 mutation. Nature (2000) 2.07
1,25-Dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line. Infect Immun (1998) 1.96
The pressure developed in muscle during contraction. J Physiol (1948) 1.81
Strong HLA class I--restricted T cell responses in dengue hemorrhagic fever: a double-edged sword? J Infect Dis (2001) 1.79
Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine. J Infect Dis (1999) 1.76
The analysis of galvanometer curves. J Physiol (1930) 1.76
Enhancement of MHC class I-restricted peptide-specific T cell induction by a DNA prime/MVA boost vaccination regime. Vaccine (1998) 1.74
Induction of CD8+ T cells using heterologous prime-boost immunisation strategies. Immunol Rev (1999) 1.72
Heterozygote advantage for HLA class-II type in hepatitis B virus infection. Nat Genet (1997) 1.71
An empirical exploration of the (delta mu)2 genetic distance for 213 human microsatellite markers. Am J Hum Genet (1999) 1.66
Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria. J Infect Dis (1998) 1.66
The heat-producton of surviving amphibian muscles, during rest, activity, and rigor. J Physiol (1912) 1.65
A protein particle vaccine containing multiple malaria epitopes. Nat Biotechnol (1997) 1.61
The energy degraded in the recovery processes of stimulated muscles. J Physiol (1913) 1.60
Human CD8+ CTL specific for the mycobacterial major secreted antigen 85A. J Immunol (2000) 1.58
Melanesians and Polynesians share a unique alpha-thalassemia mutation. Am J Hum Genet (1985) 1.58
Parasite virulence and disease patterns in Plasmodium falciparum malaria. Proc Natl Acad Sci U S A (1994) 1.57
Independent recombination events between the duplicated human alpha globin genes; implications for their concerted evolution. Nucleic Acids Res (1984) 1.54
Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles. J Infect Dis (1999) 1.54
A major susceptibility locus for leprosy in India maps to chromosome 10p13. Nat Genet (2001) 1.48
HTLV-1, HIV-1, hepatitis B and hepatitis delta in the Pacific and South-East Asia: a serological survey. Epidemiol Infect (1988) 1.46
Interleukin 10-mediated immunosuppression by a variant CD4 T cell epitope of Plasmodium falciparum. Immunity (1999) 1.45
Polymorphism of the TRAP gene of Plasmodium falciparum. Proc Biol Sci (1990) 1.45
Unique T cell effector functions elicited by Plasmodium falciparum epitopes in malaria-exposed Africans tested by three T cell assays. J Immunol (2001) 1.45
Association of vitamin D receptor genotype with leprosy type. J Infect Dis (1999) 1.44
Recombination within the human embryonic xi-globin locus: a common xi-xi chromosome produced by gene conversion of the psi xi gene. Cell (1985) 1.43
Report of a consultation on the optimization of clinical challenge trials for evaluation of candidate blood stage malaria vaccines, 18-19 March 2009, Bethesda, MD, USA. Vaccine (2009) 1.41
DNA multi-CTL epitope vaccines for HIV and Plasmodium falciparum: immunogenicity in mice. Vaccine (1998) 1.40
Optimization of a peptide-based protocol employing IL-7 for in vitro restimulation of human cytotoxic T lymphocyte precursors. J Immunol Methods (1997) 1.39
Calorimetrical experiments on warm-blooded animals. J Physiol (1913) 1.37
Interethnic genetic differentiation in Africa: HLA class I antigens in The Gambia. Am J Hum Genet (1992) 1.35
Inducible nitric oxide synthase polymorphism and fatal cerebral malaria. Lancet (1998) 1.35
Naturally processed HLA class II peptides reveal highly conserved immunogenic flanking region sequence preferences that reflect antigen processing rather than peptide-MHC interactions. J Immunol (2001) 1.34
Comparison of tests for association and linkage in incomplete families. Am J Hum Genet (2000) 1.33
High frequencies of circulating IFN-gamma-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restricted Mycobacterium tuberculosis epitope in M. tuberculosis-infected subjects without disease. Eur J Immunol (2000) 1.32
Immunogenicities of intravenous and intramuscular administrations of modified vaccinia virus Ankara-based multi-CTL epitope vaccine for human immunodeficiency virus type 1 in mice. J Gen Virol (1998) 1.32
Genetic regulation of acquired immune responses to antigens of Mycobacterium tuberculosis: a study of twins in West Africa. Infect Immun (2001) 1.29
A further analysis of the effects of high-frequency excitation of nerve. J Physiol (1935) 1.29
Tumor necrosis factor promoter polymorphism and susceptibility to lepromatous leprosy. J Infect Dis (1997) 1.27
The "inhibitory" effect of high-frequency stimulation and the excitation state of nerve. J Physiol (1935) 1.25
Altered peptide ligands narrow the repertoire of cellular immune responses by interfering with T-cell priming. Nat Med (1999) 1.24
Absence of an association between intercellular adhesion molecule 1, complement receptor 1 and interleukin 1 receptor antagonist gene polymorphisms and severe malaria in a West African population. Trans R Soc Trop Med Hyg (1998) 1.21
Assessment of the interleukin 1 gene cluster and other candidate gene polymorphisms in host susceptibility to tuberculosis. Tuber Lung Dis (1998) 1.20
The immunology of malaria infection. Curr Opin Immunol (2000) 1.19