Published in Acta Crystallogr D Biol Crystallogr on September 19, 2006
A versatile ligation-independent cloning method suitable for high-throughput expression screening applications. Nucleic Acids Res (2007) 3.22
MACSIMS: multiple alignment of complete sequences information management system. BMC Bioinformatics (2006) 2.23
TarO: a target optimisation system for structural biology. Nucleic Acids Res (2008) 1.89
Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre. Mol Microbiol (2013) 1.67
The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory. Acta Crystallogr D Biol Crystallogr (2011) 1.45
Unmet challenges of structural genomics. Curr Opin Struct Biol (2010) 1.06
Characterization of the interactions between the nucleoprotein and the phosphoprotein of Henipavirus. J Biol Chem (2011) 0.82
Purification, crystallization and preliminary X-ray characterization of a human mitochondrial phenylalanyl-tRNA synthetase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.80
The impact of structural genomics: the first quindecennial. J Struct Funct Genomics (2016) 0.79
Computational approaches to selecting and optimising targets for structural biology. Methods (2011) 0.77
Clustal W and Clustal X version 2.0. Bioinformatics (2007) 126.47
The rapid generation of mutation data matrices from protein sequences. Comput Appl Biosci (1992) 44.38
Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. Acta Crystallogr D Biol Crystallogr (2004) 31.52
CATH--a hierarchic classification of protein domain structures. Structure (1997) 29.95
AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR. J Biomol NMR (1996) 29.55
The InterPro database, an integrated documentation resource for protein families, domains and functional sites. Nucleic Acids Res (2001) 24.45
ESPript: analysis of multiple sequence alignments in PostScript. Bioinformatics (1999) 21.85
Using CLUSTAL for multiple sequence alignments. Methods Enzymol (1996) 20.99
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med (2000) 19.81
LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. Protein Eng (1995) 19.22
InterProScan: protein domains identifier. Nucleic Acids Res (2005) 18.82
GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support. Bioinformatics (1998) 15.82
Multiple sequence alignment with Clustal X. Trends Biochem Sci (1998) 15.10
Satisfying hydrogen bonding potential in proteins. J Mol Biol (1994) 14.79
Principles of protein-protein interactions. Proc Natl Acad Sci U S A (1996) 14.51
A mutation data matrix for transmembrane proteins. FEBS Lett (1994) 13.49
BAliBASE: a benchmark alignment database for the evaluation of multiple alignment programs. Bioinformatics (1999) 12.64
A comprehensive comparison of multiple sequence alignment programs. Nucleic Acids Res (1999) 12.56
PDBsum: a Web-based database of summaries and analyses of all PDB structures. Trends Biochem Sci (1997) 12.04
Three-dimensional tertiary structure of yeast phenylalanine transfer RNA. Science (1974) 11.02
The alpha/beta hydrolase fold. Protein Eng (1992) 9.94
Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein. Science (1991) 9.91
PairWise and SearchWise: finding the optimal alignment in a simultaneous comparison of a protein profile against all DNA translation frames. Nucleic Acids Res (1996) 9.82
Main-chain bond lengths and bond angles in protein structures. J Mol Biol (1993) 9.80
A structure for deoxyribose nucleic acid. 1953. Nature (2003) 9.42
PQS: a protein quaternary structure file server. Trends Biochem Sci (1998) 9.24
Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs. Nature (1990) 9.21
Stereochemical quality of protein structure coordinates. Proteins (1992) 9.18
Origin of concatemeric T7 DNA. Nat New Biol (1972) 9.08
Are all contraceptive failures unintended pregnancies? Evidence from the 1995 National Survey of Family Growth. Fam Plann Perspect (2000) 8.91
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A (2000) 8.34
Protein structural topology: Automated analysis and diagrammatic representation. Protein Sci (1999) 8.24
Case mix definition by diagnosis-related groups. Med Care (1980) 8.17
A new approach to protein fold recognition. Nature (1992) 8.17
An attempt to unify the structure of polymerases. Protein Eng (1990) 7.93
E-MSD: the European Bioinformatics Institute Macromolecular Structure Database. Nucleic Acids Res (2003) 7.79
Control of endodermal endocrine development by Hes-1. Nat Genet (2000) 7.71
CpG islands as gene markers in the human genome. Genomics (1992) 7.45
Amino acid-base interactions: a three-dimensional analysis of protein-DNA interactions at an atomic level. Nucleic Acids Res (2001) 7.27
Simultaneous comparison of three protein sequences. Proc Natl Acad Sci U S A (1985) 6.96
PROMOTIF--a program to identify and analyze structural motifs in proteins. Protein Sci (1996) 6.76
Automated image registration: II. Intersubject validation of linear and nonlinear models. J Comput Assist Tomogr (1998) 6.75
BAliBASE (Benchmark Alignment dataBASE): enhancements for repeats, transmembrane sequences and circular permutations. Nucleic Acids Res (2001) 6.67
A model recognition approach to the prediction of all-helical membrane protein structure and topology. Biochemistry (1994) 6.64
Evolution of function in protein superfamilies, from a structural perspective. J Mol Biol (2001) 6.63
InterPro--an integrated documentation resource for protein families, domains and functional sites. Bioinformatics (2000) 6.42
International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev (2000) 6.30
The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch. Nature (2000) 6.10
The pitch of chromatin DNA is reflected in its nucleotide sequence. Proc Natl Acad Sci U S A (1980) 5.88
The EMBL Nucleotide Sequence Database. Nucleic Acids Res (1999) 5.75
A direct demonstration of functional specialization in human visual cortex. J Neurosci (1991) 5.71
DbClustal: rapid and reliable global multiple alignments of protein sequences detected by database searches. Nucleic Acids Res (2000) 5.70
Automated analysis of interatomic contacts in proteins. Bioinformatics (1999) 5.60
The EMBL nucleotide sequence database. Nucleic Acids Res (2001) 5.44
Comparison of functional annotation schemes for genomes. Funct Integr Genomics (2000) 5.17
Protein superfamilies and domain superfolds. Nature (1994) 5.11
A revised set of potentials for beta-turn formation in proteins. Protein Sci (1994) 4.97
Analysis and prediction of the different types of beta-turn in proteins. J Mol Biol (1988) 4.88
Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp). Science (1991) 4.87
Influence of proline residues on protein conformation. J Mol Biol (1991) 4.87
Helix geometry in proteins. J Mol Biol (1988) 4.66
Pax6 is required for the multipotent state of retinal progenitor cells. Cell (2001) 4.65
Analysis of protein-protein interaction sites using surface patches. J Mol Biol (1997) 4.51
The general structure of transfer RNA molecules. Proc Natl Acad Sci U S A (1974) 4.30
The atomic structure of the bluetongue virus core. Nature (1998) 4.27
E-MSD: an integrated data resource for bioinformatics. Nucleic Acids Res (2005) 4.25
Atrial natriuretic factor--a circulating hormone stimulated by volume loading. Nature (1985) 4.23
Assigning genomic sequences to CATH. Nucleic Acids Res (2000) 4.22
Protein clefts in molecular recognition and function. Protein Sci (1996) 4.20
Disulphide bridges in globular proteins. J Mol Biol (1981) 4.06
Superconductivity in diamond. Nature (2004) 4.02
A mechanism for initiating RNA-dependent RNA polymerization. Nature (2001) 3.99
Protein-protein interactions: a review of protein dimer structures. Prog Biophys Mol Biol (1995) 3.98
Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. EMBO J (1999) 3.95
SOAP-based services provided by the European Bioinformatics Institute. Nucleic Acids Res (2005) 3.93
An overview of the structures of protein-DNA complexes. Genome Biol (2000) 3.90
Bacillus sporulation gene spo0H codes for sigma 30 (sigma H). J Bacteriol (1988) 3.88
Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 A. J Mol Biol (1979) 3.88
BRCA1 mutations in a population-based sample of young women with breast cancer. N Engl J Med (1996) 3.83
GeneCards: integrating information about genes, proteins and diseases. Trends Genet (1997) 3.62
Identification and classification of protein fold families. Protein Eng (1993) 3.58
Faster superoxide dismutase mutants designed by enhancing electrostatic guidance. Nature (1992) 3.56
Specific chemical and structural damage to proteins produced by synchrotron radiation. Proc Natl Acad Sci U S A (2000) 3.53
TESS: a geometric hashing algorithm for deriving 3D coordinate templates for searching structural databases. Application to enzyme active sites. Protein Sci (1997) 3.50
Walking along the rabies genome: is the large G-L intergenic region a remnant gene? Proc Natl Acad Sci U S A (1986) 3.49
PDBe: Protein Data Bank in Europe. Nucleic Acids Res (2009) 3.48
Letter: Potential biohazards of recombinant DNA molecules. Science (1974) 3.45
Nonparametric analysis of statistic images from functional mapping experiments. J Cereb Blood Flow Metab (1996) 3.44