Published in Retrovirology on October 02, 2006
Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection. PLoS One (2009) 2.23
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An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression. PLoS Pathog (2015) 1.18
Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription. J Biol Chem (2013) 1.17
Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells. J Virol (2012) 1.08
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Cyclin T1-dependent genes in activated CD4 T and macrophage cell lines appear enriched in HIV-1 co-factors. PLoS One (2008) 1.01
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Limited redundancy in genes regulated by Cyclin T2 and Cyclin T1. BMC Res Notes (2011) 0.82
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Activation of latent HIV-1 expression by the potent anti-tumor promoter 12-deoxyphorbol 13-phenylacetate. Antiviral Res (2003) 1.21
Identification of LKLF-regulated genes in quiescent CD4+ T lymphocytes. Mol Immunol (2005) 1.16
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Cyclin T1 expression is regulated by multiple signaling pathways and mechanisms during activation of human peripheral blood lymphocytes. J Immunol (2005) 1.08
Interleukin-10 inhibits HIV-1 LTR-directed gene expression in human macrophages through the induction of cyclin T1 proteolysis. Virology (2006) 1.06
Inhibition of Tat activity by the HEXIM1 protein. Retrovirology (2005) 1.03
Increased association of 7SK snRNA with Tat cofactor P-TEFb following activation of peripheral blood lymphocytes. AIDS (2003) 1.03
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HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter. J Biol Chem (2002) 0.88
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OX40 stimulation by gp34/OX40 ligand enhances productive human immunodeficiency virus type 1 infection. J Virol (2001) 0.82
miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears to involve repression of cyclin T1. PLoS Pathog (2009) 1.94
Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes. J Virol (2011) 1.32
Transient induction of cyclin T1 during human macrophage differentiation regulates human immunodeficiency virus type 1 Tat transactivation function. J Virol (2002) 1.29
Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop. J Biol Chem (2008) 1.23
Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes. J Leukoc Biol (2009) 1.19
Identification of LKLF-regulated genes in quiescent CD4+ T lymphocytes. Mol Immunol (2005) 1.16
The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble. J Virol (2010) 1.13
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Latently-infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activity. Virology (2009) 1.09
Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells. J Virol (2012) 1.08
The avian influenza virus NS1 ESEV PDZ binding motif associates with Dlg1 and Scribble to disrupt cellular tight junctions. J Virol (2011) 1.07
Interleukin-10 inhibits HIV-1 LTR-directed gene expression in human macrophages through the induction of cyclin T1 proteolysis. Virology (2006) 1.06
Cyclin T1 but not cyclin T2a is induced by a post-transcriptional mechanism in PAMP-activated monocyte-derived macrophages. J Leukoc Biol (2005) 1.04
Increased association of 7SK snRNA with Tat cofactor P-TEFb following activation of peripheral blood lymphocytes. AIDS (2003) 1.03
Induction of the HIV-1 Tat co-factor cyclin T1 during monocyte differentiation is required for the regulated expression of a large portion of cellular mRNAs. Retrovirology (2006) 1.03
Cyclin T1-dependent genes in activated CD4 T and macrophage cell lines appear enriched in HIV-1 co-factors. PLoS One (2008) 1.01
T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes. J Cell Physiol (2010) 1.00
siRNA depletion of 7SK snRNA induces apoptosis but does not affect expression of the HIV-1 LTR or P-TEFb-dependent cellular genes. J Cell Physiol (2005) 0.99
Human immunodeficiency virus type 1 infection induces cyclin T1 expression in macrophages. J Virol (2004) 0.99
miR-132 enhances HIV-1 replication. Virology (2013) 0.98
Integration of human immunodeficiency virus type 1 in untreated infection occurs preferentially within genes. J Virol (2006) 0.95
Cdk9 T-loop phosphorylation is regulated by the calcium signaling pathway. J Cell Physiol (2012) 0.92
Mini ways to stop a virus: microRNAs and HIV-1 replication. Future Virol (2011) 0.90
MicroRNA-mediated restriction of HIV-1 in resting CD4+ T cells and monocytes. Viruses (2012) 0.90
55K isoform of CDK9 associates with Ku70 and is involved in DNA repair. Biochem Biophys Res Commun (2010) 0.88
Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expression. Retrovirology (2012) 0.88
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Isolation and characterization of the human DC-SIGN and DC-SIGNR promoters. Gene (2003) 0.86
Epstein-Barr virus BART9 miRNA modulates LMP1 levels and affects growth rate of nasal NK T cell lymphomas. PLoS One (2011) 0.86
HIV-1 infection and regulation of Tat function in macrophages. Int J Biochem Cell Biol (2004) 0.83
Limited redundancy in genes regulated by Cyclin T2 and Cyclin T1. BMC Res Notes (2011) 0.82
Identification of novel CDK9 and Cyclin T1-associated protein complexes (CCAPs) whose siRNA depletion enhances HIV-1 Tat function. Retrovirology (2012) 0.82
Short communication: SAHA (vorinostat) induces CDK9 Thr-186 (T-loop) phosphorylation in resting CD4+ T cells: implications for reactivation of latent HIV. AIDS Res Hum Retroviruses (2015) 0.81
Regulation of interferon-β by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBM. PLoS One (2012) 0.77
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