James D Marks

Author PubWeight™ 89.28‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res 2006 4.43
2 Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery. Clin Cancer Res 2002 3.14
3 Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin. Nat Biotechnol 2006 2.66
4 Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids. PLoS One 2007 2.28
5 A single treatment of yttrium-90-labeled CHX-A"-C6.5 diabody inhibits the growth of established human tumor xenografts in immunodeficient mice. Cancer Res 2004 2.00
6 Antibodies from phage antibody libraries. J Immunol Methods 2004 1.75
7 Genetic and immunological comparison of anti-botulinum type A antibodies from immune and non-immune human phage libraries. Vaccine 2002 1.69
8 Influence of affinity and antigen internalization on the uptake and penetration of Anti-HER2 antibodies in solid tumors. Cancer Res 2011 1.62
9 Generation and characterization of a protective monoclonal antibody to Pseudomonas aeruginosa PcrV. J Infect Dis 2002 1.61
10 A structural perspective of the sequence variability within botulinum neurotoxin subtypes A1-A4. J Mol Biol 2006 1.59
11 Development of ligand-targeted liposomes for cancer therapy. Expert Opin Ther Targets 2004 1.48
12 Impact of single-chain Fv antibody fragment affinity on nanoparticle targeting of epidermal growth factor receptor-expressing tumor cells. J Mol Biol 2007 1.48
13 Antibody protection against botulinum neurotoxin intoxication in mice. Infect Immun 2009 1.43
14 Quantitative immuno-positron emission tomography imaging of HER2-positive tumor xenografts with an iodine-124 labeled anti-HER2 diabody. Cancer Res 2005 1.38
15 Extraction and inhibition of enzymatic activity of botulinum neurotoxins/A1, /A2, and /A3 by a panel of monoclonal anti-BoNT/A antibodies. PLoS One 2009 1.35
16 Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells. Cancer Res 2003 1.33
17 Regulation of antibody-dependent cellular cytotoxicity by IgG intrinsic and apparent affinity for target antigen. J Immunol 2007 1.32
18 Therapeutic antibodies: current state and future trends--is a paradigm change coming soon? Methods Mol Biol 2009 1.32
19 Extraction of BoNT/A, /B, /E, and /F with a single, high affinity monoclonal antibody for detection of botulinum neurotoxin by Endopep-MS. PLoS One 2010 1.28
20 Avidity-mediated enhancement of in vivo tumor targeting by single-chain Fv dimers. Clin Cancer Res 2006 1.26
21 Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β. J Clin Invest 2011 1.25
22 Mapping tumor epitope space by direct selection of single-chain Fv antibody libraries on prostate cancer cells. Cancer Res 2004 1.25
23 Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells. Mol Cancer Ther 2007 1.22
24 Phage versus phagemid libraries for generation of human monoclonal antibodies. J Mol Biol 2002 1.18
25 Affinity thresholds for membrane fusion triggering by viral glycoproteins. J Virol 2007 1.11
26 A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic alpha-exosite binding region. J Mol Biol 2010 1.10
27 Therapeutic efficacy of anti-ErbB2 immunoliposomes targeted by a phage antibody selected for cellular endocytosis. Biochim Biophys Acta 2002 1.08
28 The intracellular antibody capture technology (IACT): towards a consensus sequence for intracellular antibodies. J Mol Biol 2002 1.08
29 Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies. Mol Immunol 2007 1.07
30 Preclinical manufacture of anti-HER2 liposome-inserting, scFv-PEG-lipid conjugate. 2. Conjugate micelle identity, purity, stability, and potency analysis. Biotechnol Prog 2005 1.06
31 Isolation of scFvs to in vitro produced extracellular domains of EGFR family members. Cancer Biother Radiopharm 2005 1.06
32 An affinity matured minibody for PET imaging of prostate stem cell antigen (PSCA)-expressing tumors. Eur J Nucl Med Mol Imaging 2010 1.05
33 Towards proteome-wide production of monoclonal antibody by phage display. J Mol Biol 2002 1.05
34 Using phage display to select antibodies recognizing post-translational modifications independently of sequence context. Mol Cell Proteomics 2006 1.00
35 Yeast mating for combinatorial Fab library generation and surface display. FEBS Lett 2004 0.99
36 Recombinant full-length human IgG1s targeting hormone-refractory prostate cancer. J Mol Med (Berl) 2007 0.99
37 Effective treatment of established human breast tumor xenografts in immunodeficient mice with a single dose of the alpha-emitting radioisotope astatine-211 conjugated to anti-HER2/neu diabodies. Clin Cancer Res 2008 0.99
38 Preclinical manufacture of an anti-HER2 scFv-PEG-DSPE, liposome-inserting conjugate. 1. Gram-scale production and purification. Biotechnol Prog 2005 0.98
39 Molecular architecture of botulinum neurotoxin E revealed by single particle electron microscopy. J Biol Chem 2007 0.98
40 Redirected activity of human antitumor chimeric immune receptors is governed by antigen and receptor expression levels and affinity of interaction. J Immunother 2007 0.96
41 Characterization of highly stable liposomal and immunoliposomal formulations of vincristine and vinblastine. Cancer Chemother Pharmacol 2009 0.95
42 A novel assay for monitoring internalization of nanocarrier coupled antibodies. BMC Immunol 2006 0.95
43 Novel application of an in vitro technique to the detection and quantification of botulinum neurotoxin antibodies. J Immunol Methods 2004 0.94
44 Construction and characterization of novel, recombinant immunotoxins targeting the Her2/neu oncogene product: in vitro and in vivo studies. Cancer Res 2009 0.93
45 Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies. Mol Cancer Ther 2012 0.92
46 Tumor detection by imaging proteolytic activity. Cancer Res 2010 0.92
47 Development of a highly stable and targetable nanoliposomal formulation of topotecan. J Control Release 2009 0.92
48 Human antibodies targeting cell surface antigens overexpressed by the hormone refractory metastatic prostate cancer cells: ICAM-1 is a tumor antigen that mediates prostate cancer cell invasion. J Mol Med (Berl) 2009 0.92
49 Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines. Clin Cancer Res 2008 0.90
50 An engineered cysteine-modified diabody for imaging activated leukocyte cell adhesion molecule (ALCAM)-positive tumors. Mol Imaging Biol 2012 0.90
51 Internalizing cancer antibodies from phage libraries selected on tumor cells and yeast-displayed tumor antigens. J Mol Biol 2010 0.89
52 Single-chain antibody-based immunotoxins targeting Her2/neu: design optimization and impact of affinity on antitumor efficacy and off-target toxicity. Mol Cancer Ther 2011 0.89
53 Enzyme-amplified protein microarray and a fluidic renewable surface fluorescence immunoassay for botulinum neurotoxin detection using high-affinity recombinant antibodies. Anal Chim Acta 2006 0.88
54 Affinity maturation to improve human monoclonal antibody neutralization potency and breadth against hepatitis C virus. J Biol Chem 2011 0.88
55 N-Terminal labeling of filamentous phage to create cancer marker imaging agents. ACS Nano 2012 0.88
56 Quantum dot immunoassays in renewable surface column and 96-well plate formats for the fluorescence detection of botulinum neurotoxin using high-affinity antibodies. Biosens Bioelectron 2009 0.87
57 A functional dual-coated (FDC) microtiter plate method to replace the botulinum toxin LD50 test. Anal Biochem 2012 0.87
58 Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E. Biochem J 2013 0.86
59 Extraction and inhibition of enzymatic activity of botulinum neurotoxins /B1, /B2, /B3, /B4, and /B5 by a panel of monoclonal anti-BoNT/B antibodies. BMC Biochem 2011 0.85
60 Evaluation of the anti-HER2 C6.5 diabody as a PET radiotracer to monitor HER2 status and predict response to trastuzumab treatment. Clin Cancer Res 2010 0.84
61 Renewable surface fluorescence sandwich immunoassay biosensor for rapid sensitive botulinum toxin detection in an automated fluidic format. Analyst 2009 0.84
62 Development of human single-chain antibodies to the transferrin receptor that effectively antagonize the growth of leukemias and lymphomas. Cancer Res 2010 0.83
63 The cleavage site of C5 from man and animals as a common target for neutralizing human monoclonal antibodies: in vitro and in vivo studies. Eur J Immunol 2002 0.82
64 Simultaneous and sensitive detection of six serotypes of botulinum neurotoxin using enzyme-linked immunosorbent assay-based protein antibody microarrays. Anal Biochem 2012 0.82
65 Phage-display antibody detection of Chlamydia trachomatis-associated antigens. Microbiology 2002 0.82
66 Rapid multiplexed flow cytometric assay for botulinum neurotoxin detection using an automated fluidic microbead-trapping flow cell for enhanced sensitivity. Anal Chem 2009 0.81
67 RNA aptasensor for rapid detection of natively folded type A botulinum neurotoxin. Talanta 2013 0.80
68 Development and Implementation of Checklists for Routine Anesthesia Care: A Proposal for Improving Patient Safety. Anesth Analg 2015 0.79
69 Synergistic capture of Clostridium botulinum type A neurotoxin by scFv antibodies to novel epitopes. Biotechnol Bioeng 2011 0.79
70 Building and characterizing antibody-targeted lipidic nanotherapeutics. Methods Enzymol 2012 0.79
71 Development of human single-chain antibodies against SARS-associated coronavirus. Intervirology 2008 0.79
72 Identification of target and function specific antibodies for effective drug delivery. Methods Mol Biol 2009 0.79
73 Development of an ELISA microarray assay for the sensitive and simultaneous detection of ten biodefense toxins. Analyst 2014 0.78
74 Use of a new functional dual coating (FDC) assay to measure low toxin levels in serum and food samples following an outbreak of human botulism. J Med Microbiol 2013 0.78
75 Identifying blood-brain-barrier selective single-chain antibody fragments. Biotechnol J 2014 0.77
76 Selection and characterization of cell binding and internalizing phage antibodies. Arch Biochem Biophys 2012 0.77
77 Discovery of internalizing antibodies to tumor antigens from phage libraries. Methods Enzymol 2012 0.77
78 TSG101 exposure on the surface of HIV-1 infected cells: implications for monoclonal antibody therapy for HIV/AIDS. Am J Transl Res 2010 0.76
79 Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor. Sarcoma 2012 0.76
80 Characterization of a single-chain intrabody directed against the human receptor tyrosine kinase Ron. J Immunol Methods 2004 0.75
81 Predicting antigenic peptides suitable for the selection of phage antibodies. Hum Antibodies 2003 0.75