Published in Vaccine on September 07, 2006
Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus. J Exp Med (2008) 3.15
Telomere length and mortality: a study of leukocytes in elderly Danish twins. Am J Epidemiol (2008) 2.85
The ageing immune system: is it ever too old to become young again? Nat Rev Immunol (2009) 2.48
Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation. J Immunol (2008) 2.23
Immunosenescence: what does it mean to health outcomes in older adults? Curr Opin Immunol (2009) 2.09
Premature aging of T cells is associated with faster HIV-1 disease progression. J Acquir Immune Defic Syndr (2009) 1.78
Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults. Vaccine (2009) 1.69
The unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines. Vaccine (2012) 1.54
Causes, consequences, and reversal of immune system aging. J Clin Invest (2013) 1.50
Influenza vaccine responses in older adults. Ageing Res Rev (2010) 1.35
Role of CD8 T Cell Replicative Senescence in Human Aging and in HIV-mediated Immunosenescence. Aging Dis (2011) 1.33
Age-related changes in memory and effector T cells responding to influenza A/H3N2 and pandemic A/H1N1 strains in humans. Vaccine (2011) 1.32
T cell replicative senescence in human aging. Curr Pharm Des (2013) 1.31
Youth-specific considerations in the development of preexposure prophylaxis, microbicide, and vaccine research trials. J Acquir Immune Defic Syndr (2010) 1.24
Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway. Aging Cell (2010) 1.12
Factors that may impact on immunosenescence: an appraisal. Immun Ageing (2010) 1.09
Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus. J Virol (2010) 1.07
Cardiovascular exercise intervention improves the primary antibody response to keyhole limpet hemocyanin (KLH) in previously sedentary older adults. Brain Behav Immun (2008) 0.97
Differential effects of age, cytomegalovirus-seropositivity and end-stage renal disease (ESRD) on circulating T lymphocyte subsets. Immun Ageing (2011) 0.96
Cytomegalovirus infection induces T-cell differentiation without impairing antigen-specific responses in Gambian infants. Immunology (2008) 0.95
Understanding ageing: biomedical and bioengineering approaches, the immunologic view. Immun Ageing (2008) 0.93
Hepatitis B vaccine antibody response and the risk of clinical AIDS or death. PLoS One (2012) 0.91
Influenza vaccination in the elderly: seeking new correlates of protection and improved vaccines. Aging health (2008) 0.91
Tumor-induced senescent T cells promote the secretion of pro-inflammatory cytokines and angiogenic factors by human monocytes/macrophages through a mechanism that involves Tim-3 and CD40L. Cell Death Dis (2014) 0.90
Evaluation of hepatitis B vaccine immunogenicity among older adults during an outbreak response in assisted living facilities. Vaccine (2011) 0.89
Predicting cytotoxic T-cell age from multivariate analysis of static and dynamic biomarkers. Mol Cell Proteomics (2010) 0.88
Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression. Int J Med Sci (2009) 0.87
The importance of the age factor in cancer vaccination at older age. Cancer Immunol Immunother (2009) 0.86
The impact of aging on cancer vaccination. Curr Opin Immunol (2011) 0.83
Aging and cancer vaccines. Crit Rev Oncog (2013) 0.82
Cancer vaccines in old age. Exp Gerontol (2007) 0.81
T-Cell Immunity to Influenza in Older Adults: A Pathophysiological Framework for Development of More Effective Vaccines. Front Immunol (2016) 0.81
Interleukin-7 inhibits tumor-induced CD27-CD28- suppressor T cells: implications for cancer immunotherapy. Clin Cancer Res (2011) 0.80
Influenza vaccination in the face of immune exhaustion: is herd immunity effective for protecting the elderly? Influenza Res Treat (2012) 0.79
An age-specific CD8+ T cell pathway that impairs the effectiveness of strategies to prolong allograft survival. J Immunol (2011) 0.79
The silent war of CMV in aging and HIV infection. Mech Ageing Dev (2015) 0.79
MHC-restricted phosphopeptides from insulin receptor substrate-2 and CDC25b offer broad-based immunotherapeutic agents for cancer. Cancer Res (2014) 0.78
Is cancer vaccination feasible at older age? Exp Gerontol (2014) 0.77
Adipose-Derived Mesenchymal Stem Cells Restore Impaired Mucosal Immune Responses in Aged Mice. PLoS One (2016) 0.76
Cytolytic T-cell response against Epstein-Barr virus in lung cancer patients and healthy subjects. J Exp Clin Cancer Res (2010) 0.75
Mechanistic insights on immunosenescence and chronic immune activation in HIV-tuberculosis co-infection. World J Virol (2015) 0.75
Immunotherapy with Listeria reduces metastatic breast cancer in young and old mice through different mechanisms. Oncoimmunology (2017) 0.75
Impact of Aging and Cytomegalovirus on Immunological Response to Influenza Vaccination and Infection. Front Immunol (2017) 0.75
Cellular Immune Responses of Older Adults to Four Influenza Vaccines: Results of a Randomized, Controlled Comparison. Hum Vaccin Immunother (2017) 0.75
Shorter leukocyte telomere length is associated with higher risk of infections: a prospective study of 75,309 individuals from the general population. Haematologica (2017) 0.75
Replicative senescence of CD8 T cells: effect on human ageing. Exp Gerontol (2004) 1.09
T cell replicative senescence: pleiotropic effects on human aging. Ann N Y Acad Sci (2004) 1.04
From Hayflick to Walford: the role of T cell replicative senescence in human aging. Exp Gerontol (2004) 1.04
Impact of the Hayflick Limit on T cell responses to infection: lessons from aging and HIV disease. Mech Ageing Dev (2004) 0.81