Published in Development on October 04, 2006
A nucleator arms race: cellular control of actin assembly. Nat Rev Mol Cell Biol (2010) 5.33
Mechanism of activation of the Formin protein Daam1. Proc Natl Acad Sci U S A (2007) 1.58
Pronephric tubulogenesis requires Daam1-mediated planar cell polarity signaling. J Am Soc Nephrol (2011) 1.55
Punctuated actin contractions during convergent extension and their permissive regulation by the non-canonical Wnt-signaling pathway. J Cell Sci (2011) 1.39
Formins at a glance. J Cell Sci (2013) 1.34
A Wnt-CKIvarepsilon-Rap1 pathway regulates gastrulation by modulating SIPA1L1, a Rap GTPase activating protein. Dev Cell (2007) 1.22
Myocilin is a modulator of Wnt signaling. Mol Cell Biol (2009) 1.14
DAAM1 is a formin required for centrosome re-orientation during cell migration. PLoS One (2010) 1.09
Formins as effector proteins of Rho GTPases. Small GTPases (2014) 1.09
The formin Daam1 and fascin directly collaborate to promote filopodia formation. Curr Biol (2013) 1.08
Molecular insights on context-specific role of profilin-1 in cell migration. Cell Adh Migr (2012) 1.07
Rho-regulated myosin phosphatase establishes the level of protrusive activity required for cell movements during zebrafish gastrulation. Development (2009) 1.03
Non-redundant roles for Profilin2 and Profilin1 during vertebrate gastrulation. Dev Biol (2009) 1.01
Profilin-1 downregulation has contrasting effects on early vs late steps of breast cancer metastasis. Oncogene (2013) 0.99
TRPM7 regulates gastrulation during vertebrate embryogenesis. Dev Biol (2010) 0.98
Dynamic localization of G-actin during membrane protrusion in neuronal motility. Curr Biol (2013) 0.98
Integration of left-right Pitx2 transcription and Wnt signaling drives asymmetric gut morphogenesis via Daam2. Dev Cell (2013) 0.96
Diaphanous-related formin 2 and profilin I are required for gastrulation cell movements. PLoS One (2008) 0.93
Formins in development: orchestrating body plan origami. Biochim Biophys Acta (2008) 0.91
MIM regulates vertebrate neural tube closure. Development (2011) 0.87
Systematic analysis of microRNA fingerprints in thrombocythemic platelets using integrated platforms. Blood (2012) 0.84
Epigenetic regulation of Smad2 and Smad3 by profilin-2 promotes lung cancer growth and metastasis. Nat Commun (2015) 0.83
Piccolo Directs Activity Dependent F-Actin Assembly from Presynaptic Active Zones via Daam1. PLoS One (2015) 0.82
Defective FGF signaling causes coloboma formation and disrupts retinal neurogenesis. Cell Res (2012) 0.81
The planar cell polarity pathway directs parietal endoderm migration. Dev Biol (2009) 0.80
The role of pygopus in the differentiation of intracardiac valves in Drosophila. Genesis (2013) 0.80
Deletion of a single-copy DAAM1 gene in congenital heart defect: a case report. BMC Med Genet (2012) 0.79
DAAM family members leading a novel path into formin research. Commun Integr Biol (2011) 0.79
A high-content, multiplexed screen in human breast cancer cells identifies profilin-1 inducers with anti-migratory activities. PLoS One (2014) 0.79
Tissue patterning and cellular mechanics. J Cell Biol (2015) 0.77
Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis. Sci Rep (2015) 0.76
Custos controls β-catenin to regulate head development during vertebrate embryogenesis. Proc Natl Acad Sci U S A (2014) 0.75
Planar cell polarity (PCP) proteins and spermatogenesis. Semin Cell Dev Biol (2016) 0.75
Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. Development (2016) 0.75
Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca2+ signaling in T24M-based bladder cancer models. Oncotarget (2016) 0.75
Daam1 regulates fascin for actin assembly in mouse oocyte meiosis. Cell Cycle (2017) 0.75
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 41.47
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 26.95
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell (2010) 15.20
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med (2009) 10.54
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science (2010) 10.30
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature (2011) 6.73
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA (2008) 6.60
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science (2010) 5.86
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature (2005) 5.50
Structure of the human κ-opioid receptor in complex with JDTic. Nature (2012) 5.18
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science (2013) 5.10
JAK mutations in high-risk childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A (2009) 4.98
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Arch Gen Psychiatry (2008) 4.65
Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. Nat Genet (2009) 4.35
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science (2013) 3.72
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development (2005) 3.51
Structure of the human histamine H1 receptor complex with doxepin. Nature (2011) 3.48
Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes Dev (2003) 3.46
Acquired resistance to crizotinib from a mutation in CD74-ROS1. N Engl J Med (2013) 3.42
Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nat Neurosci (2010) 3.38
Structure of the human smoothened receptor bound to an antitumour agent. Nature (2013) 3.08
A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans. J Clin Invest (2009) 3.03
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature (2012) 2.96
MSX1 cooperates with histone H1b for inhibition of transcription and myogenesis. Science (2004) 2.87
Structure of the human glucagon class B G-protein-coupled receptor. Nature (2013) 2.86
Genomic epidemiology of a dengue virus epidemic in urban Singapore. J Virol (2009) 2.74
Nitrogen fixation island and rhizosphere competence traits in the genome of root-associated Pseudomonas stutzeri A1501. Proc Natl Acad Sci U S A (2008) 2.70
Structural features for functional selectivity at serotonin receptors. Science (2013) 2.60
Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members. J Lipid Res (2005) 2.56
Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs). Proc Natl Acad Sci U S A (2012) 2.53
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling. J Clin Invest (2002) 2.52
Risk factors for human illness with avian influenza A (H5N1) virus infection in China. J Infect Dis (2009) 2.50
Task-dependent visual-codebook compression. IEEE Trans Image Process (2011) 2.44
Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell (2013) 2.40
A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res (2008) 2.38
Remodeling of cardiac fiber structure after infarction in rats quantified with diffusion tensor MRI. Am J Physiol Heart Circ Physiol (2003) 2.30
A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs. J Infect Dis (2007) 2.22
An adenosine nucleoside inhibitor of dengue virus. Proc Natl Acad Sci U S A (2009) 2.20
Rapid transmission of hepatitis C virus among young injecting heroin users in Southern China. Int J Epidemiol (2004) 2.19
The Calcimimetic agent AMG 073 lowers plasma parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism. J Am Soc Nephrol (2002) 2.18
AnimalTFDB: a comprehensive animal transcription factor database. Nucleic Acids Res (2011) 2.15
Epidermal growth factor receptor mutations and their correlation with gefitinib therapy in patients with non-small cell lung cancer: a meta-analysis based on updated individual patient data from six medical centers in mainland China. J Thorac Oncol (2007) 2.15
SnapShot: Noncanonical Wnt Signaling Pathways. Cell (2007) 2.14
Wnt signal transduction pathways. Organogenesis (2008) 2.14
Serologic survey of pandemic (H1N1) 2009 virus, Guangxi Province, China. Emerg Infect Dis (2009) 2.13
Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab (2008) 2.10
Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice. J Clin Invest (2009) 2.09
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Structure (2012) 2.08
Quantitative hepatic CT perfusion measurement: comparison of Couinaud's hepatic segments with dual-source 128-slice CT. Eur J Radiol (2012) 2.06
Toxicity and penetration of TiO2 nanoparticles in hairless mice and porcine skin after subchronic dermal exposure. Toxicol Lett (2009) 2.04
LysM-type mycorrhizal receptor recruited for rhizobium symbiosis in nonlegume Parasponia. Science (2010) 2.02
Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cells. BMC Cell Biol (2008) 2.00
Sensorineural hearing loss associated with neomycin eardrops and nonintact tympanic membranes. Otolaryngol Head Neck Surg (2012) 1.98
TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol (2008) 1.97
Small molecule activation of PKM2 in cancer cells induces serine auxotrophy. Chem Biol (2012) 1.96
MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. J Mol Med (Berl) (2008) 1.93
Promotion and attenuation of FGF signaling through the Ras-MAPK pathway. Sci STKE (2004) 1.93
A genome-wide association study identifies two new risk loci for Graves' disease. Nat Genet (2011) 1.92
Regional ventricular wall thickening reflects changes in cardiac fiber and sheet structure during contraction: quantification with diffusion tensor MRI. Am J Physiol Heart Circ Physiol (2005) 1.91
The DIX domain targets dishevelled to actin stress fibres and vesicular membranes. Nature (2002) 1.89
Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42. Biochemistry (2006) 1.88
Comparison of helix interactions in membrane and soluble alpha-bundle proteins. Biophys J (2002) 1.88
Structural basis for molecular recognition at serotonin receptors. Science (2013) 1.86
'Social evils' and harm reduction: the evolving policy environment for human immunodeficiency virus prevention among injection drug users in China and Vietnam. Addiction (2007) 1.85
The calcimimetic AMG 073 reduces parathyroid hormone and calcium x phosphorus in secondary hyperparathyroidism. Kidney Int (2003) 1.82
A component of the ARC/Mediator complex required for TGF beta/Nodal signalling. Nature (2002) 1.82
Molecular determinants of Mg2+ and Ca2+ permeability and pH sensitivity in TRPM6 and TRPM7. J Biol Chem (2007) 1.75
Identification of Sef, a novel modulator of FGF signalling. Nat Cell Biol (2002) 1.75
TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain. J Biol Chem (2006) 1.75
Specialized and redundant roles of TBP and a vertebrate-specific TBP paralog in embryonic gene regulation in Xenopus. Proc Natl Acad Sci U S A (2004) 1.74
Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity. Proc Natl Acad Sci U S A (2012) 1.74
Golgi inheritance in mammalian cells is mediated through endoplasmic reticulum export activities. Mol Biol Cell (2005) 1.73
MRI features of pigmented villonodular synovitis (PVNS). Clin Rheumatol (2004) 1.73
Generation of genetically modified mice by oocyte injection of androgenetic haploid embryonic stem cells. Cell (2012) 1.72
Identification of Francisella tularensis genes affected by iron limitation. Infect Immun (2006) 1.72
A five-city trial of a behavioural intervention to reduce sexually transmitted disease/HIV risk among sex workers in China. AIDS (2007) 1.72
The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells. PLoS One (2009) 1.72
trans-Diaqua-bis[5-carb-oxy-4-carboxyl-ato-2-(4-pyridinio)-1H-imidazol-1-ido-κN,O]iron(II). Acta Crystallogr Sect E Struct Rep Online (2009) 1.72
Cellular magnetic resonance imaging: current status and future prospects. Expert Rev Med Devices (2006) 1.71
The adult Drosophila malpighian tubules are maintained by multipotent stem cells. Cell Stem Cell (2007) 1.70
Acupuncture for essential hypertension. Int J Cardiol (2013) 1.70
Cinacalcet hydrochloride is an effective treatment for secondary hyperparathyroidism in patients with CKD not receiving dialysis. Am J Kidney Dis (2005) 1.69
Soluble syndecan-1 promotes growth of myeloma tumors in vivo. Blood (2002) 1.69
MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G. Cancer Lett (2008) 1.68
Condom use among female sex workers in China: role of gatekeepers. Sex Transm Dis (2005) 1.67
Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell (2013) 1.66
MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2. Gastroenterology (2012) 1.64
Cholesterol biosynthesis modulation regulates dengue viral replication. Virology (2009) 1.64
Density-functional theory with screened van der Waals interactions for the modeling of hybrid inorganic-organic systems. Phys Rev Lett (2012) 1.63
Isolation and characterization of cancer stem like cells in human glioblastoma cell lines. Cancer Lett (2009) 1.62
Detecting and profiling tissue-selective genes. Physiol Genomics (2006) 1.61
Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions. Development (2002) 1.60
Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nat Genet (2007) 1.59
Climate variability and hemorrhagic fever with renal syndrome transmission in Northeastern China. Environ Health Perspect (2010) 1.59
New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering. J Cell Biol (2009) 1.58
Mechanism of activation of the Formin protein Daam1. Proc Natl Acad Sci U S A (2007) 1.58