Published in Biochem J on January 15, 2007
Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs. Methods Enzymol (2009) 3.26
Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump. Proc Natl Acad Sci U S A (2013) 1.15
Alzheimer's disease and blood-brain barrier function-Why have anti-beta-amyloid therapies failed to prevent dementia progression? Neurosci Biobehav Rev (2009) 0.97
The Arabidopsis peroxisomal ABC transporter, comatose, complements the Saccharomyces cerevisiae pxa1 pxa2Delta mutant for metabolism of long-chain fatty acids and exhibits fatty acyl-CoA-stimulated ATPase activity. J Biol Chem (2010) 0.96
Anthelmintics are substrates and activators of nematode P glycoprotein. Antimicrob Agents Chemother (2011) 0.91
A single S1034C mutation confers altered drug sensitivity to PfMDR1 ATPase activity that is characteristic of the 7G8 isoform. Mol Biochem Parasitol (2007) 0.90
ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin. J Lipid Res (2012) 0.83
Bile salt-stimulated phospholipid efflux mediated by ABCB4 localized in nonraft membranes. J Lipid Res (2013) 0.83
Regulation of the function of the human ABCG2 multidrug transporter by cholesterol and bile acids: effects of mutations in potential substrate and steroid binding sites. Drug Metab Dispos (2014) 0.81
Cholesterol fill-in model: mechanism for substrate recognition by ABC proteins. J Bioenerg Biomembr (2007) 0.81
Gene expression profiling of transporters in the solute carrier and ATP-binding cassette superfamilies in human eye substructures. Mol Pharm (2013) 0.80
Evaluation of the contribution of the ATP binding cassette transporter, P-glycoprotein, to in vivo cholesterol homeostasis. Mol Pharm (2013) 0.79
Small substrate transport and mechanism of a molybdate ATP binding cassette transporter in a lipid environment. J Biol Chem (2014) 0.78
Plasma LDL cholesterol has no impact on P-glycoprotein (MDR1/ABCB1) activity in human peripheral blood mononuclear cells. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.76
Measurement and Clinical Significance of Biomarkers of Oxidative Stress in Humans. Oxid Med Cell Longev (2017) 0.75
Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem (1993) 10.95
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell (1986) 8.53
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta (1976) 7.41
Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol (1999) 6.62
Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc Natl Acad Sci U S A (1987) 4.43
How proteins move lipids and lipids move proteins. Nat Rev Mol Cell Biol (2001) 3.26
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc Natl Acad Sci U S A (2002) 3.09
Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain. Mol Cell (2004) 3.07
A method for the determination of inorganic phosphate in the presence of labile organic phosphate and high concentrations of protein: application to lens ATPases. Anal Biochem (1988) 2.91
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. Proc Natl Acad Sci U S A (1997) 2.91
MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine. Cell (1996) 2.87
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. J Clin Invest (1999) 2.57
Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase. J Biol Chem (1992) 2.42
P-glycoprotein and multidrug resistance. Curr Opin Genet Dev (1996) 2.33
Cholesterol binding by the bacterial type III translocon is essential for virulence effector delivery into mammalian cells. Mol Microbiol (2005) 2.32
Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein. Proc Natl Acad Sci U S A (1997) 2.10
Communication between multiple drug binding sites on P-glycoprotein. Mol Pharmacol (2000) 1.87
Simultaneous binding of two different drugs in the binding pocket of the human multidrug resistance P-glycoprotein. J Biol Chem (2003) 1.79
Both P-glycoprotein nucleotide-binding sites are catalytically active. J Biol Chem (1995) 1.61
ATP-binding cassette transporter AI and its role in HDL formation. Curr Opin Lipidol (2005) 1.46
Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein. J Biol Chem (1996) 1.40
Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoprotein. J Biol Chem (1997) 1.38
Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site. Eur J Biochem (1999) 1.33
Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein. J Biol Chem (2002) 1.28
Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis. J Biol Chem (2002) 1.25
Transmembrane segment 1 of human P-glycoprotein contributes to the drug-binding pocket. Biochem J (2006) 1.23
Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites. J Biol Chem (2003) 1.22
Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein. J Biol Chem (1993) 1.22
The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane. Proc Natl Acad Sci U S A (2002) 1.15
Purification and ATPase activity of human ABCA1. J Biol Chem (2006) 1.14
Identification of residues in the drug-binding domain of human P-glycoprotein. Analysis of transmembrane segment 11 by cysteine-scanning mutagenesis and inhibition by dibromobimane. J Biol Chem (1999) 1.02
Expression of the human oxytocin receptor in baculovirus-infected insect cells: high-affinity binding is induced by a cholesterol-cyclodextrin complex. Biochemistry (1995) 1.01
P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance. Biochem Biophys Res Commun (1989) 1.00
Allosteric modulation of human P-glycoprotein. Inhibition of transport by preventing substrate translocation and dissociation. J Biol Chem (2003) 1.00
Modulation of cellular cholesterol alters P-glycoprotein activity in multidrug-resistant cells. Mol Pharmacol (2004) 0.99
The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influence. Eur Biophys J (2001) 0.98
Structural basis of the KcsA K(+) channel and agitoxin2 pore-blocking toxin interaction by using the transferred cross-saturation method. Structure (2003) 0.98
P-glycoprotein retains function when reconstituted into a sphingolipid- and cholesterol-rich environment. J Lipid Res (2004) 0.95
Synthetic hydrophobic peptides are substrates for P-glycoprotein and stimulate drug transport. Biochem J (1996) 0.94
Microanalysis for MDR1 ATPase by high-performance liquid chromatography with a titanium dioxide column. Anal Biochem (2004) 0.94
Alteration of substrate specificity by mutations at the His61 position in predicted transmembrane domain 1 of human MDR1/P-glycoprotein. Biochemistry (1997) 0.91
Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein. Biochim Biophys Acta (1998) 0.90
Control of P-glycoprotein activity by membrane cholesterol amounts and their relation to multidrug resistance in human CEM leukemia cells. Biochemistry (2005) 0.89
Amino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity. FEBS Lett (1997) 0.82
Functional reconstitution of P-glycoprotein reveals an apparent near stoichiometric drug transport to ATP hydrolysis. J Biol Chem (1996) 0.81
Cholesterol modulates P-glycoprotein activity in human peripheral blood mononuclear cells. Biochem Biophys Res Commun (2004) 0.79
Structural basis for the spectral difference in luciferase bioluminescence. Nature (2006) 3.60
Structural basis for gibberellin recognition by its receptor GID1. Nature (2008) 2.54
Crystal structure of the C-terminal clock-oscillator domain of the cyanobacterial KaiA protein. Nat Struct Mol Biol (2004) 2.08
Spatial distribution and functional significance of activated vinculin in living cells. J Cell Biol (2005) 1.77
Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner. Arterioscler Thromb Vasc Biol (2005) 1.64
Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1. J Lipid Res (2006) 1.52
Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica. Proc Natl Acad Sci U S A (2003) 1.45
Prevalence of dry eye disease and its risk factors in visual display terminal users: the Osaka study. Am J Ophthalmol (2013) 1.37
Early gastric cancer with Krukenberg tumor and review of cases of intramucosal gastric cancers with Krukenberg tumor. J Gastroenterol (2003) 1.36
Vinexin, CAP/ponsin, ArgBP2: a novel adaptor protein family regulating cytoskeletal organization and signal transduction. Cell Struct Funct (2002) 1.35
Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca2+-calmodulin. Nat Struct Biol (2003) 1.30
Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis. J Biol Chem (2002) 1.25
SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor. J Biol Chem (2003) 1.22
Crystal structure of a myristoylated CAP-23/NAP-22 N-terminal domain complexed with Ca2+/calmodulin. EMBO J (2004) 1.22
Human ABCA3, a product of a responsible gene for abca3 for fatal surfactant deficiency in newborns, exhibits unique ATP hydrolysis activity and generates intracellular multilamellar vesicles. Biochem Biophys Res Commun (2004) 1.20
Characterization and classification of ATP-binding cassette transporter ABCA3 mutants in fatal surfactant deficiency. J Biol Chem (2006) 1.20
Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog. Proc Natl Acad Sci U S A (2014) 1.14
Purification and ATPase activity of human ABCA1. J Biol Chem (2006) 1.14
Early removal of drains and the incidence of seroma after breast surgery. Breast Cancer (2013) 1.13
Mechanism of multidrug recognition by MDR1/ABCB1. Cancer Sci (2007) 1.13
Alpha1-syntrophin modulates turnover of ABCA1. J Biol Chem (2004) 1.13
Crystal structure of the PsbP protein of photosystem II from Nicotiana tabacum. EMBO Rep (2004) 1.12
Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis. Proc Natl Acad Sci U S A (2004) 1.11
The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression. Mol Biol Cell (2010) 1.10
Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation. Genes Cells (2008) 1.07
Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact. J Biol Chem (2003) 1.06
Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein. J Biol Chem (2003) 1.06
Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7. J Lipid Res (2005) 1.03
Lipid outward translocation by ABC proteins. FEBS Lett (2010) 1.02
ABC proteins: key molecules for lipid homeostasis. Med Mol Morphol (2005) 1.02
Posttranscriptional regulation of human ABCA7 and its function for the apoA-I-dependent lipid release. Biochem Biophys Res Commun (2003) 1.02
Bile salt-dependent efflux of cellular phospholipids mediated by ATP binding cassette protein B4. Hepatology (2007) 1.01
Direct interaction of nuclear liver X receptor-beta with ABCA1 modulates cholesterol efflux. J Biol Chem (2008) 1.00
Loop-mediated isothermal amplification method for rapid detection of the periodontopathic bacteria Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola. J Clin Microbiol (2005) 0.99
Down-regulation of CD9 in human ovarian carcinoma cell might contribute to peritoneal dissemination: morphologic alteration and reduced expression of beta1 integrin subsets. Cancer Res (2005) 0.99
Enhanced apoA-I-dependent cholesterol efflux by ABCA1 from sphingomyelin-deficient Chinese hamster ovary cells. J Biol Chem (2007) 0.99
Direct interaction of Cucurbitacin E isolated from Alsomitra macrocarpa to actin filament. Cytotechnology (2007) 0.99
Sodium taurocholate-dependent lipid efflux by ABCA1: effects of W590S mutation on lipid translocation and apolipoprotein A-I dissociation. J Lipid Res (2009) 0.98
Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins. J Biol Chem (2004) 0.98
KATP channel interaction with adenine nucleotides. J Mol Cell Cardiol (2005) 0.98
Sphingomyelin-dependence of cholesterol efflux mediated by ABCG1. J Lipid Res (2007) 0.97
Reassessment of the in vivo functions of DNA polymerase I and RNase H in bacterial cell growth. J Bacteriol (2007) 0.97
ATP binding/hydrolysis by and phosphorylation of peroxisomal ATP-binding cassette proteins PMP70 (ABCD3) and adrenoleukodystrophy protein (ABCD1). J Biol Chem (2002) 0.96
Enzymatic measurement of phosphatidic acid in cultured cells. J Lipid Res (2009) 0.96
ABCA1 dimer-monomer interconversion during HDL generation revealed by single-molecule imaging. Proc Natl Acad Sci U S A (2013) 0.95
Structure and binding mode of a ribosome recycling factor (RRF) from mesophilic bacterium. J Biol Chem (2002) 0.95
Crystal structure of the Homer 1 family conserved region reveals the interaction between the EVH1 domain and own proline-rich motif. J Mol Biol (2002) 0.95
Serum amyloid A generates high density lipoprotein with cellular lipid in an ABCA1- or ABCA7-dependent manner. J Lipid Res (2006) 0.95
Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition. Proc Natl Acad Sci U S A (2013) 0.94
Liver X receptor beta (LXRbeta) interacts directly with ATP-binding cassette A1 (ABCA1) to promote high density lipoprotein formation during acute cholesterol accumulation. J Biol Chem (2011) 0.94
Microanalysis for MDR1 ATPase by high-performance liquid chromatography with a titanium dioxide column. Anal Biochem (2004) 0.94
Characterization of berberine transport into Coptis japonica cells and the involvement of ABC protein. J Exp Bot (2002) 0.93
Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A. Biochem Biophys Res Commun (2003) 0.93
Structural basis for docking of peroxisomal membrane protein carrier Pex19p onto its receptor Pex3p. EMBO J (2010) 0.93
Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists. Mol Cancer Ther (2003) 0.92
Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production. Oncotarget (2014) 0.92
Cloning of ABCA17, a novel rodent sperm-specific ABC (ATP-binding cassette) transporter that regulates intracellular lipid metabolism. Biochem J (2005) 0.92
Active-site architecture of endopolygalacturonase I from Stereum purpureum revealed by crystal structures in native and ligand-bound forms at atomic resolution. Biochemistry (2002) 0.92
Functional role of the linker region in purified human P-glycoprotein. FEBS J (2009) 0.92
Function and regulation of ABCA1--membrane meso-domain organization and reorganization. FEBS J (2011) 0.92
Role of interaction with vinculin in recruitment of vinexins to focal adhesions. Biochem Biophys Res Commun (2005) 0.91
Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism. Arterioscler Thromb Vasc Biol (2004) 0.91
Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins. Biochim Biophys Acta (2010) 0.91
Successful utilization of coronary covered stents to treat a common hepatic artery pseudoaneurysm secondary to pancreatic fistula after Whipple's procedure: report of a case. Surg Today (2009) 0.91
Formation of two intramolecular disulfide bonds is necessary for ApoA-I-dependent cholesterol efflux mediated by ABCA1. J Biol Chem (2009) 0.90
ATP-binding cassette transporter A1 is involved in hepatic alpha-tocopherol secretion. J Nutr Biochem (2009) 0.90