Published in Mol Biol Evol on October 13, 2006
Neuroligins and neurexins link synaptic function to cognitive disease. Nature (2008) 9.23
Neurexins physically and functionally interact with GABA(A) receptors. Neuron (2010) 1.48
Use of zebrafish as a model to understand mechanisms of addiction and complex neurobehavioral phenotypes. Neurobiol Dis (2010) 1.20
Using zebrafish to assess the impact of drugs on neural development and function. Expert Opin Drug Discov (2009) 1.08
The tissue-specific RNA binding protein T-STAR controls regional splicing patterns of neurexin pre-mRNAs in the brain. PLoS Genet (2013) 1.03
Neurexins. Genome Biol (2013) 1.02
The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions. Proc Natl Acad Sci U S A (2009) 1.02
Bridging the synaptic gap: neuroligins and neurexin I in Apis mellifera. PLoS One (2008) 0.98
New insights into molecular pathways associated with flatfish ovarian development and atresia revealed by transcriptional analysis. BMC Genomics (2009) 0.90
Neurexins, neuroligins and LRRTMs: synaptic adhesion getting fishy. J Neurochem (2011) 0.85
Origin and loss of nested LRRTM/α-catenin genes during vertebrate evolution. PLoS One (2014) 0.79
Transcriptomic analysis of maternally provisioned cues for phenotypic plasticity in the annual killifish, Austrofundulus limnaeus. Evodevo (2017) 0.75
Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature (2003) 3.42
Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biol (2009) 2.16
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT. J Cell Biol (2002) 1.97
Mammalian tumor xenografts induce neovascularization in zebrafish embryos. Cancer Res (2007) 1.79
Modeling the early stages of vascular network assembly. EMBO J (2003) 1.78
Integrins and angiogenesis: a sticky business. Exp Cell Res (2005) 1.69
Angiopoietin-2 expression in breast cancer correlates with lymph node invasion and short survival. Int J Cancer (2003) 1.69
Sema4D induces angiogenesis through Met recruitment by Plexin B1. Blood (2005) 1.65
Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1. J Cell Biol (2005) 1.61
Sox18 and Sox7 play redundant roles in vascular development. Blood (2007) 1.60
HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma. Nat Med (2002) 1.59
Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models. J Clin Invest (2009) 1.56
Modeling human tumor angiogenesis in a three-dimensional culture system. Blood (2013) 1.55
The synaptic proteins β-neurexin and neuroligin synergize with extracellular matrix-binding vascular endothelial growth factor a during zebrafish vascular development. Arterioscler Thromb Vasc Biol (2012) 1.50
SoxF genes: Key players in the development of the cardio-vascular system. Int J Biochem Cell Biol (2009) 1.41
Diffusion-limited phase separation in eukaryotic chemotaxis. Proc Natl Acad Sci U S A (2005) 1.41
Involvement of chemokine receptor 4/stromal cell-derived factor 1 system during osteosarcoma tumor progression. Clin Cancer Res (2005) 1.37
Essential role of PDK1 in regulating endothelial cell migration. J Cell Biol (2007) 1.35
Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish. Arterioscler Thromb Vasc Biol (2010) 1.35
Stable vascular connections and remodeling require full expression of VE-cadherin in zebrafish embryos. PLoS One (2009) 1.28
Aminopeptidase A is a functional target in angiogenic blood vessels. Cancer Cell (2004) 1.28
Antiangiogenic and vascular-targeting activity of the microtubule-destabilizing trans-resveratrol derivative 3,5,4'-trimethoxystilbene. Mol Pharmacol (2005) 1.27
Inhibition of vascular endothelial growth factor receptor 2-mediated endothelial cell activation by Axl tyrosine kinase receptor. Blood (2004) 1.21
Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways. Mol Cancer (2009) 1.20
Targeting oncogenic serine/threonine-protein kinase BRAF in cancer cells inhibits angiogenesis and abrogates hypoxia. Proc Natl Acad Sci U S A (2011) 1.16
Identification of CD36 molecular features required for its in vitro angiostatic activity. FASEB J (2005) 1.14
Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice. J Clin Invest (2012) 1.11
The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling. Cell Res (2012) 1.10
Type I collagen limits VEGFR-2 signaling by a SHP2 protein-tyrosine phosphatase-dependent mechanism 1. Circ Res (2005) 1.07
Besides adhesion: new perspectives of integrin functions in angiogenesis. Cardiovasc Res (2008) 1.06
In vivo activation of JAK2/STAT-3 pathway during angiogenesis induced by GM-CSF. FASEB J (2001) 1.06
Ectopic expression and knockdown of a zebrafish sox21 reveal its role as a transcriptional repressor in early development. Mech Dev (2004) 1.04
Temporal and spatial modulation of Rho GTPases during in vitro formation of capillary vascular network. Adherens junctions and myosin light chain as targets of Rac1 and RhoA. J Biol Chem (2003) 1.04
Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor. Blood (2006) 1.04
Activation of diacylglycerol kinase alpha is required for VEGF-induced angiogenic signaling in vitro. Oncogene (2004) 1.03
IL-12 regulates an endothelial cell-lymphocyte network: effect on metalloproteinase-9 production. J Immunol (2003) 1.02
The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions. Proc Natl Acad Sci U S A (2009) 1.02
Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores. Proc Natl Acad Sci U S A (2011) 1.01
Semaphorins and tumor angiogenesis. Angiogenesis (2009) 1.01
LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms. Atherosclerosis (2009) 1.01
CCL16 activates an angiogenic program in vascular endothelial cells. Blood (2003) 1.00
Increased expression of alpha6 integrin in endothelial cells unveils a proangiogenic role for basement membrane. Cancer Res (2010) 1.00
Differential regulation of the zebrafish orthopedia 1 gene during fate determination of diencephalic neurons. BMC Dev Biol (2006) 1.00
Abeta peptides accelerate the senescence of endothelial cells in vitro and in vivo, impairing angiogenesis. FASEB J (2010) 0.99
Integrin signaling and lung cancer. Cell Adh Migr (2010) 0.99
Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1. Blood (2003) 0.97
Neurexins and neuroligins: synapses look out of the nervous system. Cell Mol Life Sci (2011) 0.96
3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner. Neoplasia (2012) 0.96
Common cues in vascular and axon guidance. Physiology (Bethesda) (2004) 0.96
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma. J Control Release (2010) 0.96
Hyperthermia inhibits angiogenesis by a plasminogen activator inhibitor 1-dependent mechanism. Cancer Res (2003) 0.96
Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells. J Biol Chem (2003) 0.95
Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase. Blood (2011) 0.95
An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin. Nat Neurosci (2012) 0.94
Neuropilin-1 identifies a subset of bone marrow Gr1- monocytes that can induce tumor vessel normalization and inhibit tumor growth. Cancer Res (2012) 0.94
Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production. J Virol (2004) 0.94
Hypoxia/reoxygenation cardiac injury and regeneration in zebrafish adult heart. PLoS One (2013) 0.94
Loss of inhibitory semaphorin 3A (SEMA3A) autocrine loops in bone marrow endothelial cells of patients with multiple myeloma. Blood (2006) 0.94
A fluorescent one-dimensional photonic crystal for label-free biosensing based on BLOCH surface waves. Sensors (Basel) (2013) 0.93
Gorham-Stout syndrome: a monocyte-mediated cytokine propelled disease. J Bone Miner Res (2005) 0.93
The miR-126 regulates angiopoietin-1 signaling and vessel maturation by targeting p85β. Biochim Biophys Acta (2012) 0.91
A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6. EMBO Mol Med (2012) 0.91
Abrogation of prostaglandin E2/EP4 signaling impairs the development of rag1+ lymphoid precursors in the thymus of zebrafish embryos. J Immunol (2007) 0.90
Integrins team up with tyrosine kinase receptors and plexins to control angiogenesis. Curr Opin Hematol (2008) 0.90
Insulin-like growth factor binding protein-3 is overexpressed in endothelial cells of mouse breast tumor vessels. Int J Cancer (2003) 0.90
Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein. Blood (2004) 0.89
Integration of microfluidic and cantilever technology for biosensing application in liquid environment. Biosens Bioelectron (2010) 0.88
Protein kinase D1 regulates VEGF-A-induced alphavbeta3 integrin trafficking and endothelial cell migration. Traffic (2010) 0.88
Crucial role of zebrafish prox1 in hypothalamic catecholaminergic neurons development. BMC Dev Biol (2008) 0.87
Angiopoietin-like 7, a novel pro-angiogenetic factor over-expressed in cancer. Angiogenesis (2014) 0.87
Vasculogenic potential of long term repopulating cord blood progenitors. FASEB J (2004) 0.86
Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2. Arterioscler Thromb Vasc Biol (2012) 0.86
Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages. J Immunol (2012) 0.86
Osteopontin overexpression inhibits in vitro re-endothelialization via integrin engagement. J Biol Chem (2007) 0.85
A peek inside the neurosecretory brain through Orthopedia lenses. Dev Dyn (2008) 0.85
Unraveling the influence of endothelial cell density on VEGF-A signaling. Blood (2012) 0.85
Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution. Development (2013) 0.85
Integrins: a flexible platform for endothelial vascular tyrosine kinase receptors. Autoimmun Rev (2007) 0.85
Nervous vascular parallels: axon guidance and beyond. Int J Dev Biol (2011) 0.84
Sox factors transcriptionally regulate ROBO4 gene expression in developing vasculature in zebrafish. J Biol Chem (2011) 0.84
Endothelial fate and angiogenic properties of human CD34+ progenitor cells in zebrafish. Arterioscler Thromb Vasc Biol (2011) 0.84
The HMGB protein gene family in zebrafish: Evolution and embryonic expression patterns. Gene Expr Patterns (2010) 0.84
Induced early expression of mrf4 but not myog rescues myogenesis in the myod/myf5 double-morphant zebrafish embryo. J Cell Sci (2009) 0.84
Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings. J Control Release (2013) 0.84
Sox18 genetically interacts with VegfC to regulate lymphangiogenesis in zebrafish. Arterioscler Thromb Vasc Biol (2013) 0.83