| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function.
|
Proc Natl Acad Sci U S A
|
2007
|
5.36
|
|
2
|
Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation.
|
Proc Natl Acad Sci U S A
|
2012
|
2.28
|
|
3
|
Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease.
|
Am J Pathol
|
2008
|
2.15
|
|
4
|
Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function.
|
Proc Natl Acad Sci U S A
|
2011
|
1.82
|
|
5
|
A monobromobimane-based assay to measure the pharmacokinetic profile of reactive sulphide species in blood.
|
Br J Pharmacol
|
2010
|
1.75
|
|
6
|
The effects of therapeutic sulfide on myocardial apoptosis in response to ischemia-reperfusion injury.
|
Eur J Cardiothorac Surg
|
2008
|
1.68
|
|
7
|
Therapeutic applications of PARP inhibitors: anticancer therapy and beyond.
|
Mol Aspects Med
|
2013
|
1.62
|
|
8
|
Inhibition of neuronal nitric oxide synthase in ovine model of acute lung injury.
|
Crit Care Med
|
2009
|
1.57
|
|
9
|
Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE).
|
Br J Pharmacol
|
2013
|
1.56
|
|
10
|
Anti-inflammatory adjuvant in resuscitation fluids improves survival in hemorrhage.
|
Crit Care Med
|
2009
|
1.51
|
|
11
|
Therapeutic injection of PARP inhibitor INO-1001 preserves cardiac function in porcine myocardial ischemia and reperfusion without reducing infarct size.
|
Shock
|
2010
|
1.44
|
|
12
|
Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics.
|
FASEB J
|
2012
|
1.44
|
|
13
|
Nebulized nitric oxide/nucleophile adduct reduces pulmonary vascular resistance in mechanically ventilated septicemic sheep.
|
Crit Care Med
|
2005
|
1.40
|
|
14
|
Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep.
|
Am J Physiol Lung Cell Mol Physiol
|
2003
|
1.32
|
|
15
|
Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury.
|
J Thorac Cardiovasc Surg
|
2009
|
1.27
|
|
16
|
Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation.
|
Clin Sci (Lond)
|
2008
|
1.27
|
|
17
|
Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft.
|
Mol Cancer Ther
|
2005
|
1.23
|
|
18
|
Alpha7 cholinergic-agonist prevents systemic inflammation and improves survival during resuscitation.
|
J Cell Mol Med
|
2008
|
1.22
|
|
19
|
Detection of exhaled hydrogen sulphide gas in healthy human volunteers during intravenous administration of sodium sulphide.
|
Br J Clin Pharmacol
|
2010
|
1.18
|
|
20
|
The therapeutic potential of cystathionine β-synthetase/hydrogen sulfide inhibition in cancer.
|
Antioxid Redox Signal
|
2014
|
1.17
|
|
21
|
Effect of hydrogen sulfide in a porcine model of myocardial ischemia-reperfusion: comparison of different administration regimens and characterization of the cellular mechanisms of protection.
|
J Cardiovasc Pharmacol
|
2009
|
1.11
|
|
22
|
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects.
|
Br J Pharmacol
|
2014
|
1.10
|
|
23
|
Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis.
|
Hepatology
|
2014
|
1.09
|
|
24
|
Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced septic shock.
|
Biochem Pharmacol
|
2003
|
1.05
|
|
25
|
Beneficial effect of a hydrogen sulphide donor (sodium sulphide) in an ovine model of burn- and smoke-induced acute lung injury.
|
Br J Pharmacol
|
2009
|
1.03
|
|
26
|
gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury.
|
Free Radic Biol Med
|
2008
|
1.02
|
|
27
|
Poly(ADP-ribose) polymerase inhibition improves postischemic myocardial function after cardioplegia-cardiopulmonary bypass.
|
J Am Coll Surg
|
2003
|
1.01
|
|
28
|
Critical role of reactive nitrogen species in lung ischemia-reperfusion injury.
|
J Heart Lung Transplant
|
2003
|
1.00
|
|
29
|
Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress.
|
Biochem Pharmacol
|
2011
|
1.00
|
|
30
|
Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide.
|
Br J Pharmacol
|
2009
|
0.99
|
|
31
|
Thioglycine and L-thiovaline: biologically active H₂S-donors.
|
Bioorg Med Chem
|
2012
|
0.97
|
|
32
|
Molecular biological effects of selective neuronal nitric oxide synthase inhibition in ovine lung injury.
|
Am J Physiol Lung Cell Mol Physiol
|
2009
|
0.97
|
|
33
|
Neuronal nitric oxide synthase inhibition attenuates cardiopulmonary dysfunctions after combined burn and smoke inhalation injury in sheep.
|
Crit Care Med
|
2008
|
0.97
|
|
34
|
Toxicological and pathophysiological roles of reactive oxygen and nitrogen species.
|
Toxicology
|
2010
|
0.96
|
|
35
|
Indices of apoptosis activation after blood cardioplegia and cardiopulmonary bypass.
|
Circulation
|
2006
|
0.95
|
|
36
|
Effect of hydrogen sulfide on myocardial protection in the setting of cardioplegia and cardiopulmonary bypass.
|
Interact Cardiovasc Thorac Surg
|
2010
|
0.95
|
|
37
|
Cell-based screening identifies paroxetine as an inhibitor of diabetic endothelial dysfunction.
|
Diabetes
|
2012
|
0.92
|
|
38
|
Potential role of hydrogen sulfide in the pathogenesis of vascular dysfunction in septic shock.
|
Curr Vasc Pharmacol
|
2013
|
0.92
|
|
39
|
Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway.
|
Biochem Biophys Res Commun
|
2013
|
0.92
|
|
40
|
Hydrogen sulfide-mediated stimulation of mitochondrial electron transport involves inhibition of the mitochondrial phosphodiesterase 2A, elevation of cAMP and activation of protein kinase A.
|
Biochem Pharmacol
|
2013
|
0.92
|
|
41
|
Reduction of hemorrhagic transformation by PJ34, a poly(ADP-ribose)polymerase inhibitor, after permanent focal cerebral ischemia in mice.
|
Eur J Pharmacol
|
2008
|
0.90
|
|
42
|
Time profile of oxidative stress and neutrophil activation in ovine acute lung injury and sepsis.
|
Shock
|
2012
|
0.90
|
|
43
|
Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of cecal ligation and puncture.
|
Crit Care
|
2014
|
0.89
|
|
44
|
Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damage.
|
PLoS One
|
2013
|
0.89
|
|
45
|
Identification of pharmacological modulators of HMGB1-induced inflammatory response by cell-based screening.
|
PLoS One
|
2013
|
0.89
|
|
46
|
PARP as a Drug Target for the Therapy of Diabetic Cardiovascular Dysfunction.
|
Drug News Perspect
|
2002
|
0.88
|
|
47
|
Nebulization with γ-tocopherol ameliorates acute lung injury after burn and smoke inhalation in the ovine model.
|
Shock
|
2012
|
0.88
|
|
48
|
Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients.
|
J Gerontol A Biol Sci Med Sci
|
2012
|
0.88
|
|
49
|
Severe Burn Injury Induces Thermogenically Functional Mitochondria in Murine White Adipose Tissue.
|
Shock
|
2015
|
0.87
|
|
50
|
Recombinant human activated protein C attenuates cardiovascular and microcirculatory dysfunction in acute lung injury and septic shock.
|
Crit Care
|
2010
|
0.87
|
|
51
|
MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells.
|
Diabetes
|
2006
|
0.85
|
|
52
|
Poly (ADP) ribose synthetase inhibition in alveolar macrophages undergoing hypoxia and reoxygenation.
|
Exp Mol Pathol
|
2007
|
0.85
|
|
53
|
Regulation of kinase cascade activation and heat shock protein expression by poly(ADP-ribose) polymerase inhibition in doxorubicin-induced heart failure.
|
J Cardiovasc Pharmacol
|
2011
|
0.84
|
|
54
|
Gene expression reprogramming protects macrophage from septic-induced cell death.
|
Mol Immunol
|
2010
|
0.84
|
|
55
|
Intratracheal poly (ADP) ribose synthetase inhibition ameliorates lung ischemia reperfusion injury.
|
Ann Thorac Surg
|
2004
|
0.84
|
|
56
|
Hydrogen Sulfide and Cancer.
|
Handb Exp Pharmacol
|
2015
|
0.84
|
|
57
|
Activation of the cholinergic antiinflammatory pathway reduces ricin-induced mortality and organ failure in mice.
|
Mol Med
|
2009
|
0.84
|
|
58
|
AP39, A Mitochondrially Targeted Hydrogen Sulfide Donor, Exerts Protective Effects in Renal Epithelial Cells Subjected to Oxidative Stress in Vitro and in Acute Renal Injury in Vivo.
|
Shock
|
2016
|
0.83
|
|
59
|
Aerosolized linear polyethylenimine-nitric oxide/nucleophile adduct attenuates endotoxin-induced lung injury in sheep.
|
Am J Respir Crit Care Med
|
2002
|
0.83
|
|
60
|
The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.
|
J Endocrinol
|
2008
|
0.83
|
|
61
|
Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor.
|
Ann Thorac Surg
|
2002
|
0.83
|
|
62
|
Enhanced peroxynitrite decomposition protects against experimental obliterative bronchiolitis.
|
Exp Mol Pathol
|
2003
|
0.82
|
|
63
|
The Flagellin-TLR5 Axis: Therapeutic Opportunities.
|
Drug News Perspect
|
2002
|
0.82
|
|
64
|
Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates angiotensin AT2 receptor (AT2R) and AT2R binding protein (ATBP) genes.
|
Biochem Pharmacol
|
2009
|
0.82
|
|
65
|
Stent placement in patients with coronary heart disease decreases plasma levels of the endogenous nitric oxide synthase inhibitor ADMA.
|
Int J Mol Med
|
2009
|
0.82
|
|
66
|
Excessive stimulation of poly(ADP-ribosyl)ation contributes to endothelial dysfunction in pre-eclampsia.
|
Br J Pharmacol
|
2005
|
0.82
|
|
67
|
Influence of PARP-1 polymorphisms in patients after traumatic brain injury.
|
J Neurotrauma
|
2010
|
0.82
|
|
68
|
Poly(adenosine diphosphate ribose) polymerase inhibition modulates spinal cord dysfunction after thoracoabdominal aortic ischemia-reperfusion.
|
J Vasc Surg
|
2005
|
0.81
|
|
69
|
The novel inosine analogue INO-2002 exerts an anti-inflammatory effect in a murine model of acute lung injury.
|
Shock
|
2009
|
0.81
|
|
70
|
Endotoxin tolerance: selective alterations in gene expression and protection against lymphocyte death.
|
Immunobiology
|
2009
|
0.80
|
|
71
|
Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock.
|
Shock
|
2016
|
0.79
|
|
72
|
Quantification of PARP activity in human tissues: ex vivo assays in blood cells and immunohistochemistry in human biopsies.
|
Methods Mol Biol
|
2011
|
0.79
|
|
73
|
Short-term effects of glipizide (an adenosine triphosphate-sensitive potassium channel inhibitor) on cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep.
|
Shock
|
2006
|
0.79
|
|
74
|
Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 2. Efficacy studies in allergic and pulmonary inflammation models in vivo.
|
Br J Pharmacol
|
2013
|
0.78
|
|
75
|
Burn and smoke injury activates poly(ADP-ribose)polymerase in circulating leukocytes.
|
Shock
|
2011
|
0.78
|
|
76
|
Beneficial pulmonary effects of a metalloporphyrinic peroxynitrite decomposition catalyst in burn and smoke inhalation injury.
|
Am J Physiol Lung Cell Mol Physiol
|
2010
|
0.78
|
|
77
|
Endothelial dysfunction as predictor of mortality in sepsis.
|
Crit Care Med
|
2011
|
0.78
|
|
78
|
Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 1. Effects on inflammatory cell activation and chemotaxis in vitro and pharmacokinetic characterization in vivo.
|
Br J Pharmacol
|
2013
|
0.78
|
|
79
|
Bacterial lysine decarboxylase influences human dental biofilm lysine content, biofilm accumulation, and subclinical gingival inflammation.
|
J Periodontol
|
2011
|
0.78
|
|
80
|
Role of peroxynitrite anion in renal hypothermic preservation injury.
|
Transplantation
|
2005
|
0.77
|
|
81
|
Pathomechanisms of myocardial dysfunction in sepsis.
|
Endocr Metab Immune Disord Drug Targets
|
2010
|
0.77
|
|
82
|
Role of poly (ADP) ribose synthetase in lung ischemia-reperfusion injury.
|
J Heart Lung Transplant
|
2004
|
0.77
|
|
83
|
The Angiotensin-converting enzyme inhibitor captopril inhibits poly(adp-ribose) polymerase activation and exerts beneficial effects in an ovine model of burn and smoke injury.
|
Shock
|
2011
|
0.76
|
|
84
|
Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis.
|
Mol Med
|
2013
|
0.76
|
|
85
|
Hydrogen sulfide and PKG in ischemia-reperfusion injury: sources, signaling, accelerators and brakes.
|
Basic Res Cardiol
|
2015
|
0.75
|
|
86
|
Free radical scavenging as a therapeutic strategy for bacteremia.
|
Crit Care Med
|
2005
|
0.75
|
|
87
|
Correction: Intraluminal Flagellin Differentially Contributes to Gut Dysbiosis and Systemic Inflammation following Burn Injury.
|
PLoS One
|
2017
|
0.75
|
|
88
|
Hungary: academy needs more than internal reform.
|
Nature
|
2006
|
0.75
|
|
89
|
Poly(ADP-ribose) activation in circulating cells in human myocardial infarction.
|
Int J Cardiol
|
2007
|
0.75
|
|
90
|
'Professor Galveston' has departed. Obituary--Daniel Traber.
|
Crit Care
|
2012
|
0.75
|
|
91
|
Integrin-mediated suppression of endotoxin-induced DNA damage in lung endothelial cells is sensitive to poly(ADP-ribose) polymerase-1 gene deletion.
|
Int J Mol Med
|
2003
|
0.75
|