PubRank

Carsten Korth

Author PubWeight™ 44.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Understanding the role of DISC1 in psychiatric disease and during normal development. J Neurosci 2009 1.89
2 Genes contributing to prion pathogenesis. J Gen Virol 2008 1.51
3 Quinpramine is a novel compound effective in ameliorating brain autoimmune disease. Exp Neurol 2008 1.44
4 Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease. J Neurosci 2008 1.32
5 C-terminal fragment of N-cadherin accelerates synapse destabilization by amyloid-β. Brain 2012 1.20
6 Rapidly progressive Alzheimer disease. Arch Neurol 2011 1.19
7 Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proc Natl Acad Sci U S A 2010 1.18
8 alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation. J Neurochem 2009 1.15
9 Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments. J Neurochem 2006 1.13
10 Convergence of two independent mental disease genes on the protein level: recruitment of dysbindin to cell-invasive disrupted-in-schizophrenia 1 aggresomes. Biol Psychiatry 2011 1.11
11 Oligomer assembly of the C-terminal DISC1 domain (640-854) is controlled by self-association motifs and disease-associated polymorphism S704C. Biochemistry 2009 1.07
12 Human prion strain selection in transgenic mice. Ann Neurol 2010 1.06
13 Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure. J Neurochem 2010 1.02
14 Oral treatment with the d-enantiomeric peptide D3 improves the pathology and behavior of Alzheimer's Disease transgenic mice. ACS Chem Neurosci 2010 0.98
15 A chimeric ligand approach leading to potent antiprion active acridine derivatives: design, synthesis, and biological investigations. J Med Chem 2006 0.96
16 Endothelial LRP1 transports amyloid-β1-42 across the blood-brain barrier. J Clin Invest 2015 0.93
17 Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits. Hum Mol Genet 2012 0.89
18 Live imaging of prions reveals nascent PrPSc in cell-surface, raft-associated amyloid strings and webs. J Cell Biol 2014 0.88
19 The expanded octarepeat domain selectively binds prions and disrupts homomeric prion protein interactions. J Biol Chem 2005 0.87
20 Cellular prion protein participates in amyloid-β transcytosis across the blood-brain barrier. J Cereb Blood Flow Metab 2012 0.86
21 Vaccine approaches to prevent and treat prion infection : progress and challenges. BioDrugs 2008 0.86
22 Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling. Brain 2010 0.86
23 Identification of I137M and other mutations that modulate incubation periods for two human prion strains. J Virol 2012 0.86
24 Similar structure-activity relationships of quinoline derivatives for antiprion and antimalarial effects. J Med Chem 2006 0.85
25 Combining independent drug classes into superior, synergistically acting hybrid molecules. Angew Chem Int Ed Engl 2010 0.84
26 Biological effects and use of PrPSc- and PrP-specific antibodies generated by immunization with purified full-length native mouse prions. J Virol 2011 0.84
27 Complementarity determining regions of an anti-prion protein scFv fragment orchestrate conformation specificity and antiprion activity. Mol Immunol 2008 0.84
28 Expansion of the octarepeat domain alters the misfolding pathway but not the folding pathway of the prion protein. Biochemistry 2008 0.83
29 Human and rat brain lipofuscin proteome. Proteomics 2012 0.83
30 The use of conformation-specific ligands and assays to dissect the molecular mechanisms of neurodegenerative diseases. J Neurosci Res 2007 0.82
31 Loss of prion protein leads to age-dependent behavioral abnormalities and changes in cytoskeletal protein expression. Mol Neurobiol 2014 0.80
32 Codon 129 polymorphism and the E200K mutation do not affect the cellular prion protein isoform composition in the cerebrospinal fluid from patients with Creutzfeldt-Jakob disease. Eur J Neurosci 2010 0.80
33 Prion protein gene codon 129 modulates clinical course of neurological Wilson disease. Neuroreport 2006 0.79
34 Revisiting disrupted-in-schizophrenia 1 as a scaffold protein. Biol Chem 2013 0.79
35 Aging-induced proteostatic changes in the rat hippocampus identify ARP3, NEB2 and BRAG2 as a molecular circuitry for cognitive impairment. PLoS One 2013 0.79
36 Characterization of a single-chain variable fragment recognizing a linear epitope of aβ: a biotechnical tool for studies on Alzheimer's disease? PLoS One 2013 0.79
37 Microdeletions within the hydrophobic core region of cellular prion protein alter its topology and metabolism. Biochem Biophys Res Commun 2010 0.79
38 Quinpramine--a promising compound for treating immune-mediated demyelination of the nervous system. Drug News Perspect 2010 0.78
39 N-acetylaspartate and neurofilaments as biomarkers of axonal damage in patients with progressive forms of multiple sclerosis. J Neurol 2014 0.78
40 Molecular engineering of a secreted, highly homogeneous, and neurotoxic aβ dimer. ACS Chem Neurosci 2011 0.77
41 Hybrid compounds: from simple combinations to nanomachines. BioDrugs 2012 0.77
42 Immunohistochemical characterization of novel monoclonal antibodies against the N-terminus of amyloid β-peptide. Amyloid 2013 0.77
43 Generation, purification, and characterization of cell-invasive DISC1 protein species. J Vis Exp 2012 0.76
44 Generation of topically transgenic rats by in utero electroporation and in vivo bioluminescence screening. J Vis Exp 2013 0.76
45 On the issue of transmissibility of Alzheimer disease: a critical review. Prion 2012 0.76
46 Structure-activity relationship of tocopherol derivatives suggesting a novel non-antioxidant mechanism in antiprion potency. Neurosci Lett 2009 0.76
47 Quinpramine ameliorates rat experimental autoimmune neuritis and redistributes MHC class II molecules. PLoS One 2011 0.75
48 Identification of dominant human aquaporin 4 T-cell epitopes: observations in neuromyelitis optica with implications for other autoimmune disorders. Arch Neurol 2012 0.75
49 Genetic polymorphism at codon 129 of the prion protein gene is not associated with multiple sclerosis. Arch Neurol 2009 0.75
50 No association between genetic polymorphism at codon 129 of the prion protein gene and primary progressive multiple sclerosis. Arch Neurol 2011 0.75
51 Binding of TCA to the prion protein: mechanism, implication for therapy, and application as probe for complex formation of bio-macromolecules. J Biomol Struct Dyn 2009 0.75
52 Hybridization of an Aβ-specific antibody fragment with aminopyrazole-based β-sheet ligands displays striking enhancement of target affinity. Org Biomol Chem 2015 0.75