Published in DNA Seq on April 01, 2006
Familial genes in sporadic disease: common variants of alpha-synuclein gene associate with Parkinson's disease. Mech Ageing Dev (2007) 1.36
Integrative analysis of the human cis-antisense gene pairs, miRNAs and their transcription regulation patterns. Nucleic Acids Res (2009) 1.15
Natural antisense transcripts are co-expressed with sense mRNAs in synaptoneurosomes of adult mouse forebrain. Neurosci Res (2008) 0.89
Complex sense-antisense architecture of TNFAIP1/POLDIP2 on 17q11.2 represents a novel transcriptional structural-functional gene module involved in breast cancer progression. BMC Genomics (2010) 0.87
Application of computational methods for the design of BACE-1 inhibitors: validation of in silico modelling. Int J Mol Sci (2014) 0.77
Expression of CD147, PCNA, VEGF, MMPs and their clinical significance in the giant cell tumor of bones. Int J Clin Exp Pathol (2015) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Murine double minute 2 promoter SNP309 polymorphism and prostate cancer risk: a meta-analysis. Int J Urol (2012) 2.71
Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. J Biol Chem (2003) 2.06
XRCC1 Arg399Gln, Arg194Trp and Arg280His polymorphisms in breast cancer risk: a meta-analysis. Mutagenesis (2009) 1.71
Differential effects on ARF stability by normal versus oncogenic levels of c-Myc expression. Mol Cell (2013) 1.67
TP53 Arg72Pro polymorphism and skin cancer risk: a meta-analysis. J Invest Dermatol (2010) 1.65
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nat Genet (2012) 1.64
Meta-analysis of association between TP53 Arg72Pro polymorphism and bladder cancer risk. Urology (2010) 1.55
No association between CYP1B1 Val432Leu polymorphism and breast cancer risk: a meta-analysis involving 40,303 subjects. Breast Cancer Res Treat (2009) 1.49
Human C-reactive protein binds activating Fcgamma receptors and protects myeloma tumor cells from apoptosis. Cancer Cell (2007) 1.45
A large-scale functional approach to uncover human genes and pathways in Drosophila. Cell Res (2008) 1.42
Molecular cloning and characterization of rat LC3A and LC3B--two novel markers of autophagosome. Biochem Biophys Res Commun (2005) 1.41
Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway. Carcinogenesis (2009) 1.35
Tumor-suppressive mir-663 gene induces mitotic catastrophe growth arrest in human gastric cancer cells. Oncol Rep (2010) 1.32
Human tumor microRNA signatures derived from large-scale oligonucleotide microarray datasets. Int J Cancer (2011) 1.29
Identification and characterization of nine novel human small GTPases showing variable expressions in liver cancer tissues. Gene Expr (2002) 1.27
Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasis. Clin Cancer Res (2009) 1.24
The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation. J Biol Chem (2010) 1.16
TM4SF3 promotes esophageal carcinoma metastasis via upregulating ADAM12m expression. Clin Exp Metastasis (2008) 1.14
Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells. Mol Biol Rep (2008) 1.11
Cloning and identification of the human LPAAT-zeta gene, a novel member of the lysophosphatidic acid acyltransferase family. J Hum Genet (2003) 1.11
Cloning and characterization a novel human 1-acyl-sn-glycerol-3-phosphate acyltransferase gene AGPAT7. DNA Seq (2005) 1.10
Aurora C is directly associated with Survivin and required for cytokinesis. Genes Cells (2005) 1.10
The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation. Biochem J (2012) 1.10
Nuclear export of NF90 to stabilize IL-2 mRNA is mediated by AKT-dependent phosphorylation at Ser647 in response to CD28 costimulation. J Immunol (2008) 1.09
Identification of a novel human lysophosphatidic acid acyltransferase, LPAAT-theta, which activates mTOR pathway. J Biochem Mol Biol (2006) 1.08
Phylogenetic and evolutionary analysis of the septin protein family in metazoan. FEBS Lett (2007) 1.08
Mutation analysis of 218 Chinese patients with Wilson disease revealed no correlation between the canine copper toxicosis gene MURR1 and Wilson disease. J Mol Med (Berl) (2006) 1.07
The evolution, complex structures and function of septin proteins. Cell Mol Life Sci (2009) 1.06
Survivin mutant (Surv-DD70, 71AA) disrupts the interaction of Survivin with Aurora B and causes multinucleation in HeLa cells. Biochem Biophys Res Commun (2006) 1.06
Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies. PLoS One (2013) 1.05
TNFalpha -308 G/A polymorphism is associated with breast cancer risk: a meta-analysis involving 10,184 cases and 12,911 controls. Breast Cancer Res Treat (2009) 1.05
An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk. Cancer Res (2012) 1.05
CYP1B1 and MYOC mutations in 116 Chinese patients with primary congenital glaucoma. Arch Ophthalmol (2008) 1.04
Interaction of Pin1 with Nek6 and characterization of their expression correlation in Chinese hepatocellular carcinoma patients. Biochem Biophys Res Commun (2006) 1.03
Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/alpha-lactalbumin family. Biol Reprod (2005) 1.01
GG: a domain involved in phage LTF apparatus and implicated in human MEB and non-syndromic hearing loss diseases. FEBS Lett (2006) 1.01
Cyclophilin A is upregulated in small cell lung cancer and activates ERK1/2 signal. Biochem Biophys Res Commun (2007) 1.00
Profiling tumor-associated autoantibodies for the detection of colon cancer. Clin Cancer Res (2008) 0.98
Derlin-1 is overexpressed on the tumor cell surface and enables antibody-mediated tumor targeting therapy. Clin Cancer Res (2008) 0.97
bri3, a novel gene, participates in tumor necrosis factor-alpha-induced cell death. Biochem Biophys Res Commun (2003) 0.97
Zinc finger transcription factor 191, directly binding to β-catenin promoter, promotes cell proliferation of hepatocellular carcinoma. Hepatology (2012) 0.97
Interplay between MDM2, MDMX, Pirh2 and COP1: the negative regulators of p53. Mol Biol Rep (2010) 0.96
Polymorphisms in the promoter regions of matrix metalloproteinases 1 and 3 and cancer risk: a meta-analysis of 50 case-control studies. Mutagenesis (2009) 0.96
A novel role for tissue factor pathway inhibitor-2 in the therapy of human esophageal carcinoma. Hum Gene Ther (2009) 0.96
Effect of peptide fragment size on the propensity of cyclization in collision-induced dissociation: oligoglycine b(2)-b(8). J Am Chem Soc (2009) 0.95
Linking the septin expression with carcinogenesis. Mol Biol Rep (2010) 0.94
Meta-analysis of association between matrix metalloproteinases 2, 7 and 9 promoter polymorphisms and cancer risk. Mutagenesis (2010) 0.92
HDGF-related protein-3 is required for anchorage-independent survival and chemoresistance in hepatocellular carcinomas. Gut (2012) 0.92
Codon 249 mutation in exon 7 of p53 gene in plasma DNA: maybe a new early diagnostic marker of hepatocellular carcinoma in Qidong risk area, China. World J Gastroenterol (2003) 0.92
CHDL: a cadherin-like domain in Proteobacteria and Cyanobacteria. FEMS Microbiol Lett (2005) 0.91
Fusion of human umbilical cord mesenchymal stem cells with esophageal carcinoma cells inhibits the tumorigenicity of esophageal carcinoma cells. Int J Oncol (2011) 0.91
GADD45gamma, down-regulated in 65% hepatocellular carcinoma (HCC) from 23 chinese patients, inhibits cell growth and induces cell cycle G2/M arrest for hepatoma Hep-G2 cell lines. Mol Biol Rep (2003) 0.91
The zinc finger transcription factor 191 is required for early embryonic development and cell proliferation. Exp Cell Res (2006) 0.90
IL-2 mRNA stabilization upon PMA stimulation is dependent on NF90-Ser647 phosphorylation by protein kinase CbetaI. J Immunol (2010) 0.90
Cholecystokinin, cholecystokinin-A receptor and cholecystokinin-B receptor gene polymorphisms in Parkinson's disease. Pharmacogenetics (2003) 0.90
Oligo-microarray analysis reveals the role of cyclophilin A in drug resistance. Cancer Chemother Pharmacol (2007) 0.90
Proapoptotic function of integrin beta(3) in human hepatocellular carcinoma cells. Clin Cancer Res (2009) 0.90
Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages. BMC Evol Biol (2014) 0.90
Intrapleural delivery of MSCs attenuates acute lung injury by paracrine/endocrine mechanism. J Cell Mol Med (2012) 0.89
Follistatin-like protein 1: a serum biochemical marker reflecting the severity of joint damage in patients with osteoarthritis. Arthritis Res Ther (2011) 0.89
Cyclophilin A promotes human hepatocellular carcinoma cell metastasis via regulation of MMP3 and MMP9. Mol Cell Biochem (2011) 0.89
Identification and characterization of RHEBL1, a novel member of Ras family, which activates transcriptional activities of NF-kappa B. Mol Biol Rep (2005) 0.89
Identification and characterization of D8C, a novel domain present in liver-specific LZP, uromodulin and glycoprotein 2, mutated in familial juvenile hyperuricaemic nephropathy. FEBS Lett (2004) 0.89
Human serum and glucocorticoid-inducible kinase-like kinase (SGKL) phosphorylates glycogen syntheses kinase 3 beta (GSK-3beta) at serine-9 through direct interaction. Biochem Biophys Res Commun (2002) 0.88
Retinoblastoma family protein promotes normal R8-photoreceptor differentiation in the absence of rhinoceros by inhibiting dE2F1 activity. Dev Biol (2009) 0.88
Identification and characterization of human LYPD6, a new member of the Ly-6 superfamily. Mol Biol Rep (2009) 0.88
Effects of different cross-linking conditions on the properties of genipin-cross-linked chitosan/collagen scaffolds for cartilage tissue engineering. J Mater Sci Mater Med (2010) 0.88
Cloning, expression and characterization of the human NOB1 gene. Mol Biol Rep (2005) 0.88
Destruction of DDIT3/CHOP protein by wild-type SPOP but not prostate cancer-associated mutants. Hum Mutat (2014) 0.88
TSSK5, a novel member of the testis-specific serine/threonine kinase family, phosphorylates CREB at Ser-133, and stimulates the CRE/CREB responsive pathway. Biochem Biophys Res Commun (2005) 0.87
An oral colon-targeting controlled release system based on resistant starch acetate: synthetization, characterization, and preparation of film-coating pellets. J Agric Food Chem (2011) 0.87
Reversal of P-gp and MRP1-mediated multidrug resistance by H6, a gypenoside aglycon from Gynostemma pentaphyllum, in vincristine-resistant human oral cancer (KB/VCR) cells. Eur J Pharmacol (2012) 0.87
MDM2 SNP309T>G polymorphism with hepatocellular carcinoma risk: a meta-analysis. Arch Med Res (2011) 0.87
Septin1, a new interaction partner for human serine/threonine kinase aurora-B. Biochem Biophys Res Commun (2005) 0.87
RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains. Mol Cells (2005) 0.87
BRSK2 is activated by cyclic AMP-dependent protein kinase A through phosphorylation at Thr260. Biochem Biophys Res Commun (2006) 0.87
Polycomb group protein PHF1 regulates p53-dependent cell growth arrest and apoptosis. J Biol Chem (2012) 0.87
Metallothionein MT1M is a tumor suppressor of human hepatocellular carcinomas. Carcinogenesis (2012) 0.87
A therapeutic role for mesenchymal stem cells in acute lung injury independent of hypoxia-induced mitogenic factor. J Cell Mol Med (2012) 0.86
Characterization of neuritin as a novel angiogenic factor. Biochem Biophys Res Commun (2011) 0.86
Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells. J Biol Chem (2012) 0.86
The ancient function of RB-E2F pathway: insights from its evolutionary history. Biol Direct (2010) 0.86
Structure-based identification of small molecule compounds targeting cell cyclophilin A with anti-HIV-1 activity. Eur J Pharmacol (2007) 0.85
Construction of human liver cancer vascular endothelium cDNA expression library and screening of the endothelium-associated antigen genes. World J Gastroenterol (2004) 0.85
Activation of transcriptional activities of AP1 and SRE by a novel zinc finger protein ZNF445. Gene (2005) 0.85
LAMA4, highly expressed in human hepatocellular carcinoma from Chinese patients, is a novel marker of tumor invasion and metastasis. J Cancer Res Clin Oncol (2007) 0.85
Hepatitis B virus (HBV) vaccine-induced escape mutants of HBV S gene among children from Qidong area, China. Virus Res (2004) 0.85
Meta-analysis of gene expression profiles indicates genes in spliceosome pathway are up-regulated in hepatocellular carcinoma (HCC). Med Oncol (2015) 0.85
Cloning and tissue distribution of the human B3GALT7 gene, a member of the beta1,3-Glycosyltransferase family. Glycoconj J (2004) 0.84