PubRank

Takaaki Akaike

Author PubWeight™ 67.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Protein S-guanylation by the biological signal 8-nitroguanosine 3',5'-cyclic monophosphate. Nat Chem Biol 2007 1.93
2 Helicobacter cinaedi cellulitis and bacteremia in immunocompetent hosts after orthopedic surgery. J Clin Microbiol 2006 1.63
3 Keap1 degradation by autophagy for the maintenance of redox homeostasis. Proc Natl Acad Sci U S A 2012 1.53
4 8-nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species: formation, occurrence, and implications in inflammation and carcinogenesis. Antioxid Redox Signal 2006 1.46
5 Role of nitric oxide in host defense in murine salmonellosis as a function of its antibacterial and antiapoptotic activities. Infect Immun 2002 1.39
6 Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin. Int J Cancer 2004 1.35
7 Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration. Nat Chem Biol 2012 1.32
8 In vivo antitumor activity of pegylated zinc protoporphyrin: targeted inhibition of heme oxygenase in solid tumor. Cancer Res 2003 1.31
9 Identification of and screening for human Helicobacter cinaedi infections and carriers via nested PCR. J Clin Microbiol 2012 1.20
10 Multiple contributing roles for NOS2 in LPS-induced acute airway inflammation in mice. Am J Physiol Lung Cell Mol Physiol 2003 1.17
11 Electron spin resonance detection of hydrogen peroxide as an endothelium-derived hyperpolarizing factor in porcine coronary microvessels. Arterioscler Thromb Vasc Biol 2003 1.16
12 Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization. J Clin Invest 2003 1.08
13 SMA-doxorubicin, a new polymeric micellar drug for effective targeting to solid tumours. J Control Release 2004 1.07
14 Molecular mechanism for activation and regulation of matrix metalloproteinases during bacterial infections and respiratory inflammation. Biol Chem 2004 1.04
15 Phosphoinositide 3-kinase in nitric oxide synthesis in macrophage: critical dimerization of inducible nitric-oxide synthase. J Biol Chem 2006 1.04
16 The critical role of nitric oxide signaling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response. J Biol Chem 2010 1.03
17 Complete genome sequence of Helicobacter cinaedi strain PAGU611, isolated in a case of human bacteremia. J Bacteriol 2012 1.01
18 Interleukin-1beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner. Biochem J 2005 1.00
19 Cytoprotective function of heme oxygenase 1 induced by a nitrated cyclic nucleotide formed during murine salmonellosis. J Immunol 2009 0.99
20 Potential association of Helicobacter cinaedi with atrial arrhythmias and atherosclerosis. Microbiol Immunol 2012 0.98
21 Tumor-targeted delivery of polyethylene glycol-conjugated D-amino acid oxidase for antitumor therapy via enzymatic generation of hydrogen peroxide. Cancer Res 2002 0.97
22 Nitric oxide-induced nitrative stress involved in microbial pathogenesis. J Pharmacol Sci 2005 0.97
23 Angiopoietin-related growth factor enhances blood flow via activation of the ERK1/2-eNOS-NO pathway in a mouse hind-limb ischemia model. Arterioscler Thromb Vasc Biol 2008 0.96
24 Nitrated cyclic GMP modulates guard cell signaling in Arabidopsis. Plant Cell 2013 0.94
25 Identification of bradykinin receptors in clinical cancer specimens and murine tumor tissues. Int J Cancer 2002 0.93
26 Nitric oxide as an endogenous mutagen for Sendai virus without antiviral activity. J Virol 2004 0.92
27 Angiopoietin-like protein 2 accelerates carcinogenesis by activating chronic inflammation and oxidative stress. Mol Cancer Res 2013 0.92
28 Proapoptotic effect of proteolytic activation of matrix metalloproteinases by Streptococcus pyogenes thiol proteinase (Streptococcus pyrogenic exotoxin B). Infect Immun 2004 0.90
29 Regulation by mitochondrial superoxide and NADPH oxidase of cellular formation of nitrated cyclic GMP: potential implications for ROS signalling. Biochem J 2012 0.90
30 Comparative evaluation of agar dilution and broth microdilution methods for antibiotic susceptibility testing of Helicobacter cinaedi. Microbiol Immunol 2013 0.87
31 Nitric oxide produced in Peyer's patches exhibits antiapoptotic activity contributing to an antimicrobial effect in murine salmonellosis. Microbiol Immunol 2008 0.87
32 Nitric oxide regulation of MMP-9 activation and its relationship to modifications of the cysteine switch. Biochemistry 2008 0.86
33 S-Nitrosylation of human variant albumin Liprizzi (R410C) confers potent antibacterial and cytoprotective properties. J Pharmacol Exp Ther 2006 0.85
34 Identification of the major antigenic protein of Helicobacter cinaedi and its immunogenicity in humans with H. cinaedi infections. Clin Vaccine Immunol 2008 0.85
35 Quantitative assessment of protein-bound tyrosine nitration in airway secretions from patients with inflammatory airway disease. Free Radic Res 2004 0.85
36 Antioxidative and antimutagenic activities of 4-vinyl-2,6-dimethoxyphenol (canolol) isolated from canola oil. J Agric Food Chem 2004 0.85
37 Effects of endogenous ligands on the biological role of human serum albumin in S-nitrosylation. Biochem Biophys Res Commun 2007 0.84
38 Guanine nitration in idiopathic pulmonary fibrosis and its implication for carcinogenesis. Am J Respir Crit Care Med 2006 0.84
39 Influence of membrane fluidity on human immunodeficiency virus type 1 entry. Biochem Biophys Res Commun 2005 0.84
40 S-nitrosothiols inhibit cytokine-mediated induction of matrix metalloproteinase-9 in airway epithelial cells. Am J Respir Cell Mol Biol 2002 0.84
41 Regulation of redox signaling involving chemical conjugation of protein thiols by nitric oxide and electrophiles. Bioconjug Chem 2010 0.84
42 Nitrative stress through formation of 8-nitroguanosine: insights into microbial pathogenesis. Nitric Oxide 2005 0.83
43 S-nitrosylated human serum albumin-mediated cytoprotective activity is enhanced by fatty acid binding. J Biol Chem 2008 0.83
44 Protein cysteine S-guanylation and electrophilic signal transduction by endogenous nitro-nucleotides. Amino Acids 2010 0.83
45 Superoxide generation mediated by 8-nitroguanosine, a highly redox-active nucleic acid derivative. Biochem Biophys Res Commun 2003 0.82
46 Modulation of tumor-selective vascular blood flow and extravasation by the stable prostaglandin 12 analogue beraprost sodium. J Drug Target 2003 0.81
47 Formation, signaling functions, and metabolisms of nitrated cyclic nucleotide. Nitric Oxide 2013 0.81
48 S-guanylation of human serum albumin is a unique posttranslational modification and results in a novel class of antibacterial agents. J Pharm Sci 2012 0.81
49 Suppression of NO production and 8-nitroguanosine formation by phenol-containing endocrine-disrupting chemicals in LPS-stimulated macrophages: involvement of estrogen receptor-dependent or -independent pathways. Nitric Oxide 2008 0.81
50 Midbrain dopaminergic neurons utilize nitric oxide/cyclic GMP signaling to recruit ERK that links retinoic acid receptor stimulation to up-regulation of BDNF. J Neurochem 2011 0.80
51 Mutagenicity of 8-nitroguanosine, a product of nitrative nucleoside modification by reactive nitrogen oxides, in mammalian cells. Cancer Lett 2008 0.80
52 Analysis of urinary 8-nitroguanine, a marker of nitrative nucleic acid damage, by high-performance liquid chromatography-electrochemical detection coupled with immunoaffinity purification: association with cigarette smoking. Free Radic Biol Med 2005 0.80
53 Anks4b, a novel target of HNF4α protein, interacts with GRP78 protein and regulates endoplasmic reticulum stress-induced apoptosis in pancreatic β-cells. J Biol Chem 2012 0.80
54 Hyperhomocysteinemia abrogates fasting-induced cardioprotection against ischemia/reperfusion by limiting bioavailability of hydrogen sulfide anions. J Mol Med (Berl) 2015 0.79
55 8-Nitroguanosines as chemical probes of the protein S-guanylation. Chem Commun (Camb) 2008 0.79
56 Inhibition of H3K18 deacetylation of Sirt7 by Myb-binding protein 1a (Mybbp1a). Biochem Biophys Res Commun 2013 0.79
57 Detoxification of methylmercury by hydrogen sulfide-producing enzyme in Mammalian cells. Chem Res Toxicol 2011 0.79
58 A new paradigm for antimicrobial host defense mediated by a nitrated cyclic nucleotide. J Clin Biochem Nutr 2009 0.78
59 Involvement of Salmonella enterica serovar Typhi RpoS in resistance to NO-mediated host defense against serovar Typhi infection. Microb Pathog 2006 0.78
60 Cellular uptake mechanisms and responses to NO transferred from mono- and poly-S-nitrosated human serum albumin. Free Radic Res 2011 0.78
61 Antioxidant effect of a nitrated cyclic nucleotide functioning as an endogenous electrophile. Curr Top Med Chem 2011 0.77
62 Nucleotides function as endogenous chemical sensors for oxidative stress signaling. J Clin Biochem Nutr 2010 0.77
63 redox Signaling by 8-nitro-cyclic guanosine monophosphate: nitric oxide- and reactive oxygen species-derived electrophilic messenger. Antioxid Redox Signal 2013 0.77
64 S-guanylation proteomics for redox-based mitochondrial signaling. Antioxid Redox Signal 2012 0.76
65 Methodological proof of immunochemistry for specific identification of 8-nitroguanosine 3',5'-cyclic monophosphate formed in glia cells. Nitric Oxide 2011 0.76
66 Effect of nitric oxide in amyloid fibril formation on transthyretin-related amyloidosis. Biochemistry 2005 0.76
67 Adsorption and infectivity of human immunodeficiency virus type 1 are modified by the fluidity of the plasma membrane for multiple-site binding. Microbiol Immunol 2004 0.76
68 Nitric oxide promotes recycling of 8-nitro-cGMP, a cytoprotective mediator, into intact cGMP in cells. Mol Biosyst 2012 0.76
69 S-nitrosated α-1-acid glycoprotein kills drug-resistant bacteria and aids survival in sepsis. FASEB J 2012 0.76
70 One-step preparation of S-nitrosated human serum albumin with high biological activities. Nitric Oxide 2010 0.76
71 Vascular responses to 8-nitro-cyclic GMP in non-diabetic and diabetic mice. Br J Pharmacol 2011 0.75
72 HGF-mediated inhibition of oxidative stress by 8-nitro-cGMP in high glucose-treated rat mesangial cells. Free Radic Res 2012 0.75
73 [Nitric oxide (NO) and its related compounds]. Nihon Rinsho 2010 0.75
74 Nitric oxide-induced downregulation of leptin production by 3T3-L1 adipocytes. Nitric Oxide 2006 0.75
75 [Regulation of ROS signaling for targeted cancer chemotherapy]. Nihon Rinsho 2012 0.75
76 [NO-induced mutagenesis for microbial pathogen and host defense suppression]. Nihon Rinsho 2007 0.75
77 [Nitric oxide and its related compounds]. Nihon Rinsho 2005 0.75
78 Important Role of Endothelial Caveolin-1 in the Protective Role of EDH against NO-mediated Nitrative Stress in Microcirculation in Mice. J Cardiovasc Pharmacol 2017 0.75
79 Re-emerging reactive sulfur-containing compounds and their unique biological functions. Nihon Yakurigaku Zasshi 2016 0.75
80 Frontiers in nitric oxide and redox signaling. Nitric Oxide 2011 0.75
81 Fluorescent probes for live cell imaging of endogenous Guanine nitration. Chembiochem 2013 0.75
82 Synthesis and Characterization of 8-Nitroguanosine 3',5'-Cyclic Monophosphorothioate Rp-isomer as a Potent Inhibitor of Protein Kinase G1α. Biol Pharm Bull 2016 0.75
83 Reactive sulfur species-modified protein thiols: new methods for polysulfurated protein analysis. Nihon Yakurigaku Zasshi 2016 0.75
84 [Critical role of nitrated cyclic guanine nucleotide signaling via protein S-guanylation in the antioxidant adaptive response]. Seikagaku 2012 0.75