Linda C Harris

Author PubWeight™ 11.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Alternative and aberrant splicing of MDM2 mRNA in human cancer. Cancer Cell 2002 1.70
2 MDM2 and its splice variant messenger RNAs: expression in tumors and down-regulation using antisense oligonucleotides. Mol Cancer Res 2004 1.04
3 Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins. Mol Cancer Ther 2005 0.93
4 P21Waf1/Cip1 dysfunction in neuroblastoma: a novel mechanism of attenuating G0-G1 cell cycle arrest. Cancer Res 2003 0.90
5 Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method: preclinical assessment and application to bone marrow samples from neuroblastoma patients. Cancer Res 2002 0.88
6 MDM2-A, a common Mdm2 splice variant, causes perinatal lethality, reduced longevity and enhanced senescence. Dis Model Mech 2008 0.86
7 MDM2 splice variants predominantly localize to the nucleoplasm mediated by a COOH-terminal nuclear localization signal. Mol Cancer Res 2007 0.83
8 The MDM2-a splice variant of MDM2 alters transformation in vitro and the tumor spectrum in both Arf- and p53-null models of tumorigenesis. Mol Cancer Res 2009 0.82
9 MDM2 does not influence p53-mediated sensitivity to DNA-damaging drugs. Mol Cancer Ther 2002 0.81
10 Selective chemosensitization of rhabdomyosarcoma cell lines following wild-type p53 adenoviral transduction. Anticancer Drugs 2002 0.78
11 MDM2 displays differential activities dependent upon the activation status of NFkappaB. Cancer Biol Ther 2007 0.78
12 Selection for mutations in the cDNAs of transgenic mice upon expression of an embryonic lethal protein. Transgenic Res 2007 0.78
13 Differential cooperation of oncogenes with p53 and Bax to induce apoptosis in rhabdomyosarcoma. Mol Cancer 2006 0.77
14 p53-mediated regulation of expression of a rabbit liver carboxylesterase confers sensitivity to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11). J Pharmacol Exp Ther 2003 0.75