Published in Biochim Biophys Acta on September 23, 2006
Heparan sulfate modification of the transmembrane receptor CD47 is necessary for inhibition of T cell receptor signaling by thrombospondin-1. J Biol Chem (2011) 0.99
Snake venom disintegrins and cell migration. Toxins (Basel) (2010) 0.87
Applications of snake venom components to modulate integrin activities in cell-matrix interactions. Int J Biochem Cell Biol (2013) 0.84
Tetraspanins CD9 and CD151 at the immune synapse support T-cell integrin signaling. Eur J Immunol (2014) 0.81
Rv2468c, a novel Mycobacterium tuberculosis protein that costimulates human CD4+ T cells through VLA-5. J Leukoc Biol (2011) 0.79
Mycobacterial phosphatidylinositol mannoside 6 (PIM6) up-regulates TCR-triggered HIV-1 replication in CD4+ T cells. PLoS One (2013) 0.78
Synthesis and anti-mycobacterial activity of (E)-N'-(monosubstituted-benzylidene)isonicotinohydrazide derivatives. Eur J Med Chem (2007) 2.59
Aspirin-triggered lipoxin A4 blocks reactive oxygen species generation in endothelial cells: a novel antioxidative mechanism. Thromb Haemost (2007) 1.74
Neutrophil activation by heme: implications for inflammatory processes. Blood (2002) 1.49
Snake venom disintegrins: evolution of structure and function. Toxicon (2005) 1.43
Interaction of alpha9beta1 integrin with thrombospondin-1 promotes angiogenesis. Circ Res (2007) 1.28
Cross talk between the cardiovascular and nervous systems: neurotrophic effects of vascular endothelial growth factor (VEGF) and angiogenic effects of nerve growth factor (NGF)-implications in drug development. Curr Pharm Des (2006) 1.27
Nitric oxide-dependent reduction in soluble guanylate cyclase functionality accounts for early lipopolysaccharide-induced changes in vascular reactivity. Mol Pharmacol (2005) 1.25
Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation. Blood (2006) 1.23
Fenofibrate-induced nuclear translocation of FoxO3A triggers Bim-mediated apoptosis in glioblastoma cells in vitro. Cell Cycle (2012) 1.23
Identification of novel beta1 integrin binding sites in the type 1 and type 2 repeats of thrombospondin-1. J Biol Chem (2004) 1.19
Phosphoinositide-3 kinases critically regulate the recruitment and survival of eosinophils in vivo: importance for the resolution of allergic inflammation. J Leukoc Biol (2005) 1.14
Snake venom disintegrins: novel dimeric disintegrins and structural diversification by disulphide bond engineering. Biochem J (2003) 1.10
Integrins mediate adhesion of medulloblastoma cells to tenascin and activate pathways associated with survival and proliferation. Lab Invest (2008) 1.10
Host cell lipid bodies triggered by Trypanosoma cruzi infection and enhanced by the uptake of apoptotic cells are associated with prostaglandin E₂ generation and increased parasite growth. J Infect Dis (2011) 1.08
Heme inhibits human neutrophil apoptosis: involvement of phosphoinositide 3-kinase, MAPK, and NF-kappaB. J Immunol (2004) 1.06
Augmentation of integrin-mediated mechanotransduction by hyaluronic acid. Biomaterials (2013) 1.05
Regulatory effect of nerve growth factor in alpha9beta1 integrin-dependent progression of glioblastoma. Neuro Oncol (2008) 1.02
Integrin alpha9 beta1 is a receptor for nerve growth factor and other neurotrophins. J Cell Sci (2008) 1.02
Integrin alpha2beta1 mediates the anti-angiogenic and anti-tumor activities of angiocidin, a novel tumor-associated protein. Exp Cell Res (2006) 1.01
Effect of RGD-disintegrins on melanoma cell growth and metastasis: involvement of the actin cytoskeleton, FAK and c-Fos. Toxicon (2007) 0.99
Involvement of CC chemokines in gammadelta T lymphocyte trafficking during allergic inflammation: the role of CCL2/CCR2 pathway. Int Immunol (2007) 0.97
Detrimental role of endogenous nitric oxide in host defence against Sporothrix schenckii. Immunology (2008) 0.96
Structural requirements of MLD-containing disintegrins for functional interaction with alpha 4 beta 1 and alpha 9 beta1 integrins. Biochemistry (2004) 0.95
Fibronectin extra domain-A promotes hepatic stellate cell motility but not differentiation into myofibroblasts. Gastroenterology (2011) 0.93
Late, but not early, inhibition of soluble guanylate cyclase decreases mortality in a rat sepsis model. J Pharmacol Exp Ther (2008) 0.93
Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin. Prostaglandins Other Lipid Mediat (2006) 0.93
Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-alpha, and CXCL-1. J Leukoc Biol (2008) 0.92
Leukotriene B4 mediates neutrophil migration induced by heme. J Immunol (2011) 0.91
An essential role for mast cells as modulators of neutrophils influx in collagen-induced arthritis in the mouse. Lab Invest (2010) 0.91
Role of multiple beta1 integrins in cell adhesion to the disintegrin domains of ADAMs 2 and 3. Exp Cell Res (2003) 0.90
Bone marrow mononuclear cell transplantation increases metalloproteinase-9 and 13 and decreases tissue inhibitors of metalloproteinase-1 and 2 expression in the liver of cholestatic rats. Cells Tissues Organs (2013) 0.90
Snake venomics of Bitis gabonica gabonica. Protein family composition, subunit organization of venom toxins, and characterization of dimeric disintegrins bitisgabonin-1 and bitisgabonin-2. J Proteome Res (2007) 0.90
Targeting endothelin ETA and ETB receptors inhibits antigen-induced neutrophil migration and mechanical hypernociception in mice. Naunyn Schmiedebergs Arch Pharmacol (2008) 0.89
Effect of VP12 and viperistatin on inhibition of collagen-receptor-dependent melanoma metastasis. Cancer Biol Ther (2009) 0.89
The presence of the WGD motif in CC8 heterodimeric disintegrin increases its inhibitory effect on alphaII(b)beta3, alpha(v)beta3, and alpha5beta1 integrins. Biochemistry (2002) 0.89
Fibronectin-mediated upregulation of α5β1 integrin and cell adhesion during differentiation of mouse embryonic stem cells. Cell Adh Migr (2011) 0.89
Nerve growth factor-induced protection of brain capillary endothelial cells exposed to oxygen-glucose deprivation involves attenuation of Erk phosphorylation. J Mol Neurosci (2009) 0.89
Small molecule inhibitors of integrin alpha2beta1. J Med Chem (2007) 0.88
Nerve growth factor (NGF) promotes angiogenesis in the quail chorioallantoic membrane. Endothelium (2006) 0.88
Low expression of insulin signaling molecules impairs glucose uptake in adipocytes after early overnutrition. J Endocrinol (2007) 0.88
Identification of sites in the cysteine-rich domain of the class P-III snake venom metalloproteinases responsible for inhibition of platelet function. FEBS Lett (2003) 0.88
Non-RGD-containing snake venom disintegrins, functional and structural relations. Toxicon (2011) 0.88
Involvement of alpha1beta1 integrin in insulin-like growth factor-1-mediated protection of PC12 neuronal processes from tumor necrosis factor-alpha-induced injury. J Neurosci Res (2006) 0.86
alpha(9)beta(1) integrin engagement inhibits neutrophil spontaneous apoptosis: involvement of Bcl-2 family members. Biochim Biophys Acta (2010) 0.86
Up-regulation of phosphatidylinositol 3-kinase and glucose transporter 4 in muscle of rats subjected to maternal undernutrition. Biochim Biophys Acta (2003) 0.86
KTS and RTS-disintegrins: anti-angiogenic viper venom peptides specifically targeting the alpha 1 beta 1 integrin. Curr Pharm Des (2007) 0.86
Expression of inducible nitric oxide synthase in human umbilical vein endothelial cells during primary culture. Nitric Oxide (2002) 0.86
Frutalin, a galactose-binding lectin, induces chemotaxis and rearrangement of actin cytoskeleton in human neutrophils: involvement of tyrosine kinase and phosphoinositide 3-kinase. Toxicol Appl Pharmacol (2005) 0.85
Mitochondrial localization of non-histone protein HMGB1 during human endothelial cell-Toxoplasma gondii infection. Cell Biol Int (2007) 0.85
Maternal protein restriction during early lactation induces GLUT4 translocation and mTOR/Akt activation in adipocytes of adult rats. Am J Physiol Endocrinol Metab (2008) 0.84
Characterization of a monomeric disintegrin, ocellatusin, present in the venom of the Nigerian carpet viper, Echis ocellatus. FEBS Lett (2002) 0.84
Alternagin-C, a disintegrin-like protein, induces vascular endothelial cell growth factor (VEGF) expression and endothelial cell proliferation in vitro. J Biol Chem (2004) 0.84
cDNA cloning and functional expression of jerdostatin, a novel RTS-disintegrin from Trimeresurus jerdonii and a specific antagonist of the alpha1beta1 integrin. J Biol Chem (2005) 0.84
Gedunin, a natural tetranortriterpenoid, modulates T lymphocyte responses and ameliorates allergic inflammation. Int Immunopharmacol (2012) 0.84
NMR solution structure of the non-RGD disintegrin obtustatin. J Mol Biol (2003) 0.83
Involvement of phosphatidylinositol-3 kinase-Akt and nuclear factor kappa-B pathways in the effect of frutalin on human lymphocyte. Int Immunopharmacol (2005) 0.83
Interaction between serine phosphorylated IRS-1 and beta1-integrin affects the stability of neuronal processes. J Neurosci Res (2007) 0.83
Leukotriene B4 mediates vascular smooth muscle cell migration through αvβ3 integrin transactivation. Atherosclerosis (2010) 0.83
Pro-inflammatory properties and neutrophil activation by Helicobacter pylori urease. Toxicon (2013) 0.82
Cardiac microvascular endothelial cells express and release nerve growth factor but not fibroblast growth factor-2. In Vitro Cell Dev Biol Anim (2010) 0.82
Amino acid sequence and homology modeling of obtustatin, a novel non-RGD-containing short disintegrin isolated from the venom of Vipera lebetina obtusa. Protein Sci (2003) 0.82
Structural determinants of the selectivity of KTS-disintegrins for the alpha1beta1 integrin. FEBS Lett (2004) 0.82
Angiostatic activity of obtustatin as alpha1beta1 integrin inhibitor in experimental melanoma growth. Int J Cancer (2008) 0.82
Inhibition of guanylyl cyclase restores neutrophil migration and maintains bactericidal activity increasing survival in sepsis. Shock (2011) 0.81
Nickel induces apoptosis in human neutrophils. Biometals (2012) 0.81
Concerted motions of the integrin-binding loop and the C-terminal tail of the non-RGD disintegrin obtustatin. J Biol Chem (2003) 0.81
VEGF-related protein isolated from Vipera palestinae venom, promotes angiogenesis. Growth Factors (2007) 0.81
Heme modulates intestinal epithelial cell activation: involvement of NADPHox-derived ROS signaling. Am J Physiol Cell Physiol (2012) 0.81
Importance of interaction between nerve growth factor and α9β1 integrin in glial tumor angiogenesis. Neuro Oncol (2012) 0.81
Structural requirements of KTS-disintegrins for inhibition of alpha(1)beta(1) integrin. Biochem J (2009) 0.80
Artesunate Exerts a Direct Effect on Endothelial Cell Activation and NF-κB Translocation in a Mechanism Independent of Plasmodium Killing. Malar Res Treat (2012) 0.80
An in vitro model for dengue virus infection that exhibits human monocyte infection, multiple cytokine production and dexamethasone immunomodulation. Mem Inst Oswaldo Cruz (2007) 0.80
NADPH oxidase-derived ROS: key modulators of heme-induced mitochondrial stability in human neutrophils. Exp Cell Res (2006) 0.80
Peaceful use of disastrous neurotoxicants. Neurotoxicology (2010) 0.80
Role of nitric oxide in the response of Saccharomyces cerevisiae cells to heat shock and high hydrostatic pressure. FEMS Yeast Res (2003) 0.80
NADPH oxidase activity: In the crossroad of neutrophil life and death. Front Biosci (Landmark Ed) (2009) 0.80
Alternagin-C, a nonRGD-disintegrin, induces neutrophil migration via integrin signaling. Eur J Biochem (2003) 0.80
Pharmacological aspects of Vipera xantina palestinae venom. Toxins (Basel) (2011) 0.80
Modulation of inflammatory processes by leaves extract from Clusia nemorosa both in vitro and in vivo animal models. Inflammation (2012) 0.80
Maternal protein restriction during early lactation induces changes on neutrophil activation and TNF-alpha production of adult offspring. Inflammation (2010) 0.80
Leukotriene B(4) inhibits neutrophil apoptosis via NADPH oxidase activity: redox control of NF-κB pathway and mitochondrial stability. Biochim Biophys Acta (2012) 0.79
RGD- and MLD-disintegrins, jarastatin and EC3, activate integrin-mediated signaling modulating the human neutrophils chemotaxis, apoptosis and IL-8 gene expression. Exp Cell Res (2004) 0.79
Immunolocalization of an osteopontin-like protein in dense granules of Toxoplasma gondii tachyzoites and its association with the parasitophorous vacuole. Micron (2007) 0.79
Metabonomics reveals drastic changes in anti-inflammatory/pro-resolving polyunsaturated fatty acids-derived lipid mediators in leprosy disease. PLoS Negl Trop Dis (2013) 0.79
Heme and innate immunity: new insights for an old molecule. Mem Inst Oswaldo Cruz (2006) 0.78
Modulation of T lymphocyte and eosinophil functions in vitro by natural tetranortriterpenoids isolated from Carapa guianensis Aublet. Int Immunopharmacol (2010) 0.78
Increased leptin response and inhibition of apoptosis in thymocytes of young rats offspring from protein deprived dams during lactation. PLoS One (2013) 0.78