PubRank

Manuela Aragno

Author PubWeight™ 27.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein. J Neurochem 2007 1.61
2 The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. J Neurochem 2009 1.43
3 Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion. Eur J Pharmacol 2005 1.39
4 Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells. J Endocrinol 2006 1.32
5 Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient mice. J Hepatol 2006 1.24
6 AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation. Neurobiol Aging 2010 1.21
7 Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643. Free Radic Biol Med 2006 1.16
8 4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells. J Hepatol 2004 1.14
9 Muscle wasting in diabetic and in tumor-bearing rats: role of oxidative stress. Free Radic Biol Med 2007 1.13
10 Insulin reduces cerebral ischemia/reperfusion injury in the hippocampus of diabetic rats: a role for glycogen synthase kinase-3beta. Diabetes 2008 1.04
11 Pioglitazone improves lipid and insulin levels in overweight rats on a high cholesterol and fructose diet by decreasing hepatic inflammation. Br J Pharmacol 2010 1.01
12 Treatment with the glycogen synthase kinase-3beta inhibitor, TDZD-8, affects transient cerebral ischemia/reperfusion injury in the rat hippocampus. Shock 2008 0.96
13 Peroxisome proliferator-activated receptor β/δ agonism protects the kidney against ischemia/reperfusion injury in diabetic rats. Free Radic Biol Med 2010 0.92
14 Ischemic preconditioning attenuates the oxidant-dependent mechanisms of reperfusion cell damage and death in rat liver. Liver Transpl 2002 0.92
15 Reversal of the deleterious effects of chronic dietary HFCS-55 intake by PPAR-δ agonism correlates with impaired NLRP3 inflammasome activation. Biochem Pharmacol 2012 0.91
16 High sugar intake and development of skeletal muscle insulin resistance and inflammation in mice: a protective role for PPAR- δ agonism. Mediators Inflamm 2013 0.91
17 Pro-inflammatory cytokines and oxidative stress/antioxidant parameters characterize the bio-humoral profile of early cachexia in lung cancer patients. Oncol Rep 2007 0.90
18 Effect of n-3 fatty acids on patients with advanced lung cancer: a double-blind, placebo-controlled study. Br J Nutr 2011 0.89
19 Pro-oxidant effect of dehydroepiandrosterone in rats is mediated by PPAR activation. Life Sci 2003 0.87
20 Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: a new target to treat portal hypertension? J Hepatol 2005 0.85
21 Ischaemic preconditioning modulates the activity of Kupffer cells during in vivo reperfusion injury of rat liver. Cell Biochem Funct 2003 0.83
22 Advanced glycation end products promote hepatosteatosis by interfering with SCAP-SREBP pathway in fructose-drinking mice. Am J Physiol Gastrointest Liver Physiol 2013 0.82
23 Dehydroepiandrosterone administration counteracts oxidative imbalance and advanced glycation end product formation in type 2 diabetic patients. Diabetes Care 2007 0.80
24 Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants. Bioorg Med Chem Lett 2004 0.79
25 Selective up-regulation of tumor necrosis factor receptor I in tumor-bearing rats with cancer-related cachexia. Int J Oncol 2003 0.78
26 Modulations of the calcineurin/NF-AT pathway in skeletal muscle atrophy. Biochim Biophys Acta 2007 0.78
27 Dysregulation of SREBP2 induces BACE1 expression. Neurobiol Dis 2011 0.77
28 Study of the photocatalytic transformation of synephrine: a biogenic amine relevant in anti-doping analysis. Anal Bioanal Chem 2012 0.75
29 Calcium receptors located in fibrotic septa: a new target to reduce portal pressure in liver cirrhosis. Clin Sci (Lond) 2013 0.75