Published in Nitric Oxide on October 07, 2006
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals. Cancer Metastasis Rev (2010) 2.57
Molecular targets of nutraceuticals derived from dietary spices: potential role in suppression of inflammation and tumorigenesis. Exp Biol Med (Maywood) (2009) 1.10
Molecular targets of isothiocyanates in cancer: recent advances. Mol Nutr Food Res (2014) 1.08
Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. Semin Cancer Biol (2015) 0.99
Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells. BMC Cancer (2010) 0.99
Antimicrobial activities of isothiocyanates against Campylobacter jejuni isolates. Front Cell Infect Microbiol (2012) 0.92
High-performance liquid chromatography-based method to evaluate kinetics of glucosinolate hydrolysis by Sinapis alba myrosinase. Anal Biochem (2014) 0.88
Ethyl-p-methoxycinnamate isolated from Kaempferia galanga inhibits inflammation by suppressing interleukin-1, tumor necrosis factor-α, and angiogenesis by blocking endothelial functions. Clinics (Sao Paulo) (2014) 0.84
Expression of the platelet-activating factor receptor enhances benzyl isothiocyanate-induced apoptosis in murine and human melanoma cells. Mol Med Rep (2015) 0.80
Antimicrobial activity of isothiocyanates from cruciferous plants against methicillin-resistant Staphylococcus aureus (MRSA). Int J Mol Sci (2014) 0.80
Isothiocyanates inhibit psoriasis-related proinflammatory factors in human skin. Inflamm Res (2012) 0.79
Allyl isothiocyanate ameliorates angiogenesis and inflammation in dextran sulfate sodium-induced acute colitis. PLoS One (2014) 0.77
Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women. Sci Rep (2015) 0.75
Role of macrophages in tumour progression. Immunol Lett (2009) 2.07
Ursolic acid induces apoptosis by activating p53 and caspase-3 gene expressions and suppressing NF-kappaB mediated activation of bcl-2 in B16F-10 melanoma cells. Int Immunopharmacol (2008) 1.14
Antitumour and anticarcinogenic activity of Phyllanthus amarus extract. J Ethnopharmacol (2002) 1.04
Antiangiogenic activity of berberine is mediated through the downregulation of hypoxia-inducible factor-1, VEGF, and proinflammatory mediators. Drug Chem Toxicol (2012) 0.99
Amentoflavone inhibits experimental tumor metastasis through a regulatory mechanism involving MMP-2, MMP-9, prolyl hydroxylase, lysyl oxidase, VEGF, ERK-1, ERK-2, STAT-1, NM23 and cytokines in lung tissues of C57BL/6 mice. Immunopharmacol Immunotoxicol (2008) 0.95
Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action. Indian J Exp Biol (2009) 0.94
13 cis-retinoic acid regulates cytokine production and inhibits angiogenesis by disrupting endothelial cell migration and tube formation. J Exp Ther Oncol (2008) 0.94
Antiangiogenic activity of ursolic acid. Integr Cancer Ther (2010) 0.94
Anti-metastatic effect of Biophytum sensitivum is exerted through its cytokine and immunomodulatory activity and its regulatory effect on the activation and nuclear translocation of transcription factors in B16F-10 melanoma cells. J Exp Ther Oncol (2008) 0.93
(+)-Catechin inhibits tumour angiogenesis and regulates the production of nitric oxide and TNF-alpha in LPS-stimulated macrophages. Innate Immun (2008) 0.92
Evaluation of the chemoprotective effect of Biophytum sensitivum (L.) DC extract against cyclophosphamide induced toxicity in Swiss albino mice. Drug Metabol Drug Interact (2007) 0.92
Harmine inhibits tumour specific neo-vessel formation by regulating VEGF, MMP, TIMP and pro-inflammatory mediators both in vivo and in vitro. Eur J Pharmacol (2010) 0.92
Immunomodulatory and antitumor activity of Biophytum sensitivum extract. Asian Pac J Cancer Prev (2007) 0.91
Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanoma. Chin Med (2011) 0.90
Andrographolide inhibits human umbilical vein endothelial cell invasion and migration by regulating MMP-2 and MMP-9 during angiogenesis. J Environ Pathol Toxicol Oncol (2011) 0.90
Immunopotentiating activity of abrin, a lectin from Abrus precatorius Linn. Indian J Exp Biol (2002) 0.88
Antimetastatic activity of Sulforaphane. Life Sci (2006) 0.86
Vernonia cinerea L. scavenges free radicals and regulates nitric oxide and proinflammatory cytokines profile in carrageenan induced paw edema model. Immunopharmacol Immunotoxicol (2009) 0.86
Antioxidant potential of Biophytum sensitivum extract in vitro and in vivo. J Basic Clin Physiol Pharmacol (2006) 0.86
Cardiospermum halicacabum inhibits cyclophosphamide induced immunosupression and oxidative stress in mice and also regulates iNOS and COX-2 gene expression in LPS stimulated macrophages. Asian Pac J Cancer Prev (2010) 0.86
Vernolide-A, a sesquiterpene lactone from Vernonia cinerea, induces apoptosis in B16F-10 melanoma cells by modulating p53 and caspase-3 gene expressions and regulating NF-κB-mediated bcl-2 activation. Drug Chem Toxicol (2011) 0.86
Rasayanas: evidence for the concept of prevention of diseases. Am J Chin Med (2002) 0.85
Methanol extract of Biophytum sensitivum alters the cytokine profile and inhibits iNOS and COX-2 expression in LPS/Con A stimulated macrophages. Drug Chem Toxicol (2008) 0.85
Induction of apoptosis by sulforaphane in highly metastatic B16F-10 melanoma cells. Drug Chem Toxicol (2011) 0.83
Effect of homeopathic medicines on transplanted tumors in mice. Asian Pac J Cancer Prev (2007) 0.83
Immunomodulatory and antitumor activity of Aerva lanata ethanolic extract. Immunopharmacol Immunotoxicol (2010) 0.83
Antiangiogenic activity of Diallyl Sulfide (DAS). Int Immunopharmacol (2006) 0.83
Antitumour effect of abrin on transplanted tumours in mice. Indian J Physiol Pharmacol (2002) 0.83
Dynamized preparations in cell culture. Evid Based Complement Alternat Med (2007) 0.83
Protective effect of Biophytum sensitivum (L.) DC on radiation-induced damage in mice. Immunopharmacol Immunotoxicol (2008) 0.82
Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate. Integr Cancer Ther (2007) 0.82
Modulation of cytotoxic T lymphocyte, natural killer cell, antibody-dependent cellular cytotoxicity, and antibody-dependent complement-mediated cytotoxicity by Vernonia cinerea L. and vernolide-A in BALB/c mice via enhanced production of cytokines IL-2 and IFN-γ. Immunopharmacol Immunotoxicol (2012) 0.82
Protective effect of Andrographis paniculata and andrographolide on cyclophosphamide-induced urothelial toxicity. Integr Cancer Ther (2006) 0.82
Ameliorative action of Vernonia cinerea L. on cyclophosphamide-induced immunosuppression and oxidative stress in mice. Inflammopharmacology (2010) 0.82
Inhibition of metastasis of B16F-10 melanoma cells in C57BL/6 mice by an extract of Calendula officinalis L flowers. Asian Pac J Cancer Prev (2010) 0.82
Studies on the protective effects of Boerhaavia diffusa L. against gamma radiation induced damage in mice. Integr Cancer Ther (2007) 0.82
Immunomodulatory activities of Punarnavine, an alkaloid from Boerhaavia diffusa. Immunopharmacol Immunotoxicol (2009) 0.81
Berberine inhibits pulmonary metastasis through down-regulation of MMP in metastatic B16F-10 melanoma cells. Phytother Res (2011) 0.81
Andrographolide induces apoptosis in B16F-10 melanoma cells by inhibiting NF-κB-mediated bcl-2 activation and modulating p53-induced caspase-3 gene expression. Immunopharmacol Immunotoxicol (2011) 0.81
Oleanolic acid induces apoptosis by modulating p53, Bax, Bcl-2 and caspase-3 gene expression and regulates the activation of transcription factors and cytokine profile in B16F. J Environ Pathol Toxicol Oncol (2011) 0.81
Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9. Eur J Pharmacol (2011) 0.81
Inhibition of progression of erythroleukemia induced by Friend virus in BALB/c mice by natural products--berberine, curcumin and picroliv. J Exp Ther Oncol (2008) 0.81
Effect of amentoflavone on the inhibition of pulmonary metastasis induced by B16F-10 melanoma cells in C57BL/6 mice. Integr Cancer Ther (2007) 0.80
Vernolide-A inhibits tumour specific angiogenesis by regulating proinflammatory cytokines, VEGF, MMPs and TIMP. Eur J Pharmacol (2011) 0.80
Inhibition of viral carcinogenesis by Phyllanthus amarus. Integr Cancer Ther (2009) 0.80
Nomilin inhibits metastasis via induction of apoptosis and regulates the activation of transcription factors and the cytokine profile in B16F-10 cells. Integr Cancer Ther (2011) 0.80
Tinospora cordifolia ameliorates urotoxic effect of cyclophosphamide by modulating GSH and cytokine levels. Exp Toxicol Pathol (2010) 0.80
Effect of abrin on cell-mediated immune responses in mice. Immunopharmacol Immunotoxicol (2006) 0.80
Protective role of Vernonia cinerea L. against gamma radiation--induced immunosupression and oxidative stress in mice. Hum Exp Toxicol (2010) 0.80
Effect of amentoflavone, a phenolic component from Biophytum sensitivum, on cell cycling and apoptosis of B16F-10 melanoma cells. J Environ Pathol Toxicol Oncol (2011) 0.80
Beta-carotene inhibits tumor-specific angiogenesis by altering the cytokine profile and inhibits the nuclear translocation of transcription factors in B16F-10 melanoma cells. Integr Cancer Ther (2007) 0.79
Anti-metastatic potential of Punarnavine, an alkaloid from Boerhaavia diffusa Linn. Immunobiology (2008) 0.79
Apoptotic effect of Biophytum sensitivum on B16F-10 cells and its regulatory effects on nitric oxide and cytokine production on tumor-associated macrophages. Integr Cancer Ther (2007) 0.79
Anti-tumour activity of Ruta graveolens extract. Asian Pac J Cancer Prev (2006) 0.79
Effect of Punarnavine, an alkaloid from Boerhaavia diffusa, on cell-mediated immune responses and TIMP-1 in B16F-10 metastatic melanoma-bearing mice. Immunopharmacol Immunotoxicol (2007) 0.79
Effect of vernolide-A, a sesquiterpene lactone from Vernonia cinerea L., on cell-mediated immune response in B16F-10 metastatic melanoma-bearing mice. Immunopharmacol Immunotoxicol (2011) 0.79
Ipomoea obscura ameliorates cyclophosphamide-induced toxicity by modulating the immune system and levels of proinflammatory cytokine and GSH. Can J Physiol Pharmacol (2010) 0.79
Effect of Aerva lanata on cell-mediated immune responses and cytotoxic T-lymphocyte generation in normal and tumor-bearing mice. J Immunotoxicol (2011) 0.79
Protective role of Ipomoea obscura (L.) on cyclophosphamide-induced uro- and nephrotoxicities by modulating antioxidant status and pro-inflammatory cytokine levels. Inflammopharmacology (2010) 0.78
Thujone inhibits lung metastasis induced by B16F-10 melanoma cells in C57BL/6 mice. Can J Physiol Pharmacol (2011) 0.78
Antimetastatic potential of vernolide-A, a sesquiterpenoid from Vernonia cinerea L. Hum Exp Toxicol (2011) 0.78
Induction of apoptosis of tumor cells by some potentiated homeopathic drugs: implications on mechanism of action. Integr Cancer Ther (2011) 0.78
Inhibition of angiogenic differentiation of human umbilical vein endothelial cells by diallyl disulfide (DADS). Life Sci (2006) 0.78
Antioxidant activity of Smoke Shield in-vitro and in-vivo. J Pharm Pharmacol (2003) 0.78
Augmentation of humoral and cell mediated immune responses by Thujone. Int Immunopharmacol (2011) 0.78
Modulation of immune response by Vernonia cinerea L. inhibits the proinflammatory cytokine profile, iNOS, and COX-2 expression in LPS-stimulated macrophages. Immunopharmacol Immunotoxicol (2010) 0.78
Protective effects of Rasayanas on cyclophosphamide- and radiation-induced damage. J Altern Complement Med (2002) 0.78
Inhibition of B16F-10 melanoma-induced lung metastasis in C57BL/6 mice by Aerva lanata via induction of apoptosis. Integr Cancer Ther (2012) 0.77
Evaluation of the anti-inflammatory and anti-tumor effect of Ipomoea obscura (L) and its mode of action through the inhibition of proinflammatory cytokines, nitric oxide and COX-2. Inflammation (2011) 0.77
Phyllanthus amarus inhibits cell growth and induces apoptosis in Dalton's lymphoma ascites cells through activation of caspase-3 and downregulation of Bcl-2. Integr Cancer Ther (2009) 0.77
Biophytum sensitivum (L.) DC inhibits tumor cell invasion and metastasis through a mechanism involving regulation of MMPs, prolyl hydroxylase, lysyl oxidase, nm23, ERK-1, ERK-2, STAT-1, and proinflammatory cytokine gene expression in metastatic lung tissue. Integr Cancer Ther (2008) 0.77
Radioprotective activity of naturally occurring organosulfur compounds. Tumori (2006) 0.77
Inhibition of chemically induced carcinogenesis by drugs used in homeopathic medicine. Asian Pac J Cancer Prev (2007) 0.76
13-cis-retinoic acid induces apoptosis by modulating caspase-3, bcl-2, and p53 gene expression and regulates the activation of transcription factors in B16F-10 melanoma cells. J Environ Pathol Toxicol Oncol (2008) 0.76
Punarnavine induces apoptosis in B16F-10 melanoma cells by inhibiting NF-kappaB signaling. Asian Pac J Cancer Prev (2009) 0.76
Immunostimulatory action of AC II--an ayurvedic formulation useful in HIV. Indian J Exp Biol (2008) 0.76
Anti-angiogenic effect of Biophytum sensitivum is exerted through its cytokine modulation activity and inhibitory activity against VEGF mRNA expression, endothelial cell migration and capillary tube formation. J Exp Ther Oncol (2007) 0.76
Vernolide-A inhibits radiation-induced hypoxia-mediated tumor angiogenesis by regulating HIF-1α, MMP-2, MMP-9, and VEGF. J Environ Pathol Toxicol Oncol (2011) 0.76
Boerhaavia diffusa stimulates cell-mediated immune response by upregulating IL-2 and downregulating the pro-inflammatory cytokines and GM-CSF in B16F-10 metastatic melanoma bearing mice. J Exp Ther Oncol (2008) 0.75
Effect of Thuja occidentalis and its polysaccharide on cell-mediated immune responses and cytokine levels of metastatic tumor-bearing animals. Pharm Biol (2011) 0.75
Anti-inflammatory potential of carotenoid meso-zeaxanthin and its mode of action. Pharm Biol (2015) 0.75
13 Cis-retinoic acid mediates apoptosis in Dalton's lymphoma ascites cells by regulating gene expression. J Basic Clin Physiol Pharmacol (2007) 0.75
Vernonia cinerea Less. inhibits tumor cell invasion and pulmonary metastasis in C57BL/6 mice. Integr Cancer Ther (2010) 0.75
Effect of AC II, a herbal formulation on radiation-induced immunosuppression in mice. Indian J Exp Biol (2006) 0.75
Augmentation of cellular immune response by Ipomoea obscura and Ipobscurine alkaloid attenuates tumor growth in mice. Can J Physiol Pharmacol (2011) 0.75
Effect of AC II, an herbal formulation in cyclophosphamide-induced immunosuppression in BALB/c mice--Implication in HIV treatment. Immunol Invest (2007) 0.75
Ipobscurine, an indole alkaloid from Ipomoea obscura, inhibits tumor cell invasion and experimental metastasis by inducing apoptosis. J Environ Pathol Toxicol Oncol (2011) 0.75
Anti-angiogenic activity of Ipomoea obscura extract and Ipobscurine-A. Immunopharmacol Immunotoxicol (2010) 0.75
Ipomoea obscura (L.) enhances the functions of immunological effector cells, inhibits proinflammatory cytokines and nitric oxide production by LPS induced macrophages. Immunopharmacol Immunotoxicol (2009) 0.75
Modulation of humoral immune responses and inhibition of proinflammatory cytokines and nitric oxide production by 10-methoxycanthin-6-one. Immunopharmacol Immunotoxicol (2012) 0.75
Immune response modulatory effect of Emilia sonchifolia (L.) DC: an in vivo experimental study. J Basic Clin Physiol Pharmacol (2015) 0.75
Protective role of perillic acid against radiation-induced oxidative stress, cytokine profile, DNA damage, and intestinal toxicity in mice. J Environ Pathol Toxicol Oncol (2010) 0.75
Inhibition of invasion and experimental metastasis of murine melanoma cells by Ipomoea obscura (L.) is mediated through the down-regulation of inflammatory mediators and matrix-metalloproteinases. J Exp Ther Oncol (2011) 0.75
Rutin inhibits nitric oxide and tumor necrosis factor-alpha production in lipopolysaccharide and concanavalin-a stimulated macrophages. Drug Metabol Drug Interact (2007) 0.75
Studies on anti-metastatic and anti-invasive effects of harmine using highly metastatic murine B16F-10 melanoma cells. J Environ Pathol Toxicol Oncol (2011) 0.75