|
1
|
Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.
|
Cell Metab
|
2006
|
3.66
|
|
2
|
TOR signaling.
|
Sci STKE
|
2003
|
3.61
|
|
3
|
PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.
|
J Biol Chem
|
2007
|
3.09
|
|
4
|
Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity.
|
Mol Cell Biol
|
2007
|
2.32
|
|
5
|
Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1.
|
J Biol Chem
|
2006
|
2.32
|
|
6
|
Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.
|
Diabetes
|
2010
|
2.30
|
|
7
|
Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin.
|
Proc Natl Acad Sci U S A
|
2002
|
2.06
|
|
8
|
A conserved phosphatase cascade that regulates nuclear membrane biogenesis.
|
Proc Natl Acad Sci U S A
|
2007
|
1.80
|
|
9
|
Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.
|
J Biol Chem
|
2008
|
1.73
|
|
10
|
Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load.
|
J Biol Chem
|
2002
|
1.72
|
|
11
|
Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor.
|
J Biol Chem
|
2003
|
1.72
|
|
12
|
The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin.
|
Mol Cell Biol
|
2002
|
1.68
|
|
13
|
Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1.
|
J Biol Chem
|
2006
|
1.64
|
|
14
|
Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells.
|
J Biol Chem
|
2004
|
1.54
|
|
15
|
mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin.
|
EMBO J
|
2006
|
1.51
|
|
16
|
Alterations in hepatic metabolism in fld mice reveal a role for lipin 1 in regulating VLDL-triacylglyceride secretion.
|
Arterioscler Thromb Vasc Biol
|
2008
|
1.46
|
|
17
|
Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR.
|
J Biol Chem
|
2009
|
1.34
|
|
18
|
Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors.
|
Mol Cell Biol
|
2010
|
1.28
|
|
19
|
Amino acids and leucine allow insulin activation of the PKB/mTOR pathway in normal adipocytes treated with wortmannin and in adipocytes from db/db mice.
|
FASEB J
|
2004
|
1.02
|
|
20
|
Farnesylthiosalicylic acid inhibits mammalian target of rapamycin (mTOR) activity both in cells and in vitro by promoting dissociation of the mTOR-raptor complex.
|
Mol Endocrinol
|
2004
|
1.01
|
|
21
|
Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E.
|
J Biol Chem
|
2003
|
0.97
|
|
22
|
In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.
|
J Biol Chem
|
2004
|
0.92
|
|
23
|
Effects of insulin and transgenic overexpression of UDP-glucose pyrophosphorylase on UDP-glucose and glycogen accumulation in skeletal muscle fibers.
|
J Biol Chem
|
2004
|
0.79
|
|
24
|
Effect of glycogen synthase overexpression on insulin-stimulated muscle glucose uptake and storage.
|
Am J Physiol Endocrinol Metab
|
2003
|
0.79
|
|
25
|
Evaluation of a commercial enzyme-linked immunosorbent assay for the diagnosis of bovine tuberculosis from milk samples from dairy cows.
|
Clin Vaccine Immunol
|
2013
|
0.77
|