| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A.
|
J Pharmacol Exp Ther
|
2000
|
1.56
|
|
2
|
Allocentric spatial learning by hippocampectomised rats: a further test of the "spatial mapping" and "working memory" theories of hippocampal function.
|
Q J Exp Psychol B
|
1986
|
1.53
|
|
3
|
Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains.
|
Behav Brain Res
|
1999
|
1.45
|
|
4
|
Development of SHIRPA to characterise the phenotype of gene-targeted mice.
|
Behav Brain Res
|
2001
|
1.42
|
|
5
|
A novel, potent, and selective 5-HT(7) antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl) phen ol (SB-269970).
|
J Med Chem
|
2000
|
1.42
|
|
6
|
Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1.
|
Br J Pharmacol
|
2008
|
1.32
|
|
7
|
Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function.
|
Mol Psychiatry
|
2009
|
1.22
|
|
8
|
The behavioural effects of corticotropin-releasing factor-related peptides in rats.
|
Psychopharmacology (Berl)
|
1998
|
1.11
|
|
9
|
A comparison of rectal and subcutaneous body temperature measurement in the common marmoset.
|
J Pharmacol Toxicol Methods
|
1998
|
1.10
|
|
10
|
Design and synthesis of trans-N-[4-[2-(6-cyano-1,2,3, 4-tetrahydroisoquinolin-2-yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A potent and selective dopamine D(3) receptor antagonist with high oral bioavailability and CNS penetration in the rat.
|
J Med Chem
|
2000
|
1.06
|
|
11
|
Isolation rearing induces recognition memory deficits accompanied by cytoskeletal alterations in rat hippocampus.
|
Eur J Neurosci
|
2006
|
1.05
|
|
12
|
Reaction of gadolinium chelates with endogenously available ions.
|
Magn Reson Imaging
|
1991
|
0.97
|
|
13
|
(R)-3,N-dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl) propyl]benzenesulfonamide: the first selective 5-HT7 receptor antagonist.
|
J Med Chem
|
1998
|
0.96
|
|
14
|
The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
|
J Med Chem
|
1998
|
0.96
|
|
15
|
[(3)H]-SB-269970--A selective antagonist radioligand for 5-HT(7) receptors.
|
Br J Pharmacol
|
2000
|
0.95
|
|
16
|
Neuronal plasticity, stress and depression: involvement of the cytoskeletal microtubular system?
|
Curr Drug Targets CNS Neurol Disord
|
2005
|
0.92
|
|
17
|
5-HT6 receptor antagonists enhance retention of a water maze task in the rat.
|
Psychopharmacology (Berl)
|
2001
|
0.89
|
|
18
|
Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity.
|
Psychopharmacology (Berl)
|
2001
|
0.89
|
|
19
|
Central effects of urotensin-II following ICV administration in rats.
|
Psychopharmacology (Berl)
|
2001
|
0.89
|
|
20
|
Long-term evaluation of isolation-rearing induced prepulse inhibition deficits in rats.
|
Psychopharmacology (Berl)
|
2001
|
0.89
|
|
21
|
Measurement of arginase activity.
|
Anal Biochem
|
1968
|
0.88
|
|
22
|
Evaluation of the spontaneously hypertensive rat as a model of attention deficit hyperactivity disorder: acquisition and performance of the DRL-60s test.
|
Behav Brain Res
|
2000
|
0.87
|
|
23
|
Dopamine D2 receptor stimulation inhibits cold-initiated thermogenesis in brown adipose tissue in conscious rats.
|
Neuroscience
|
2007
|
0.86
|
|
24
|
Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cells.
|
Br J Pharmacol
|
1999
|
0.83
|
|
25
|
The effects of dopamine D3/D2 receptor agonists on intracranial self stimulation in the rat.
|
Psychopharmacology (Berl)
|
1998
|
0.83
|
|
26
|
Spatial learning in the rat: impairment induced by the thiol-proteinase inhibitor, leupeptin, and an analysis of [3H]glutamate receptor binding in relation to learning.
|
Behav Neural Biol
|
1987
|
0.82
|
|
27
|
Facilitation of amphetamine-induced rotation by muscarinic antagonists is correlated with M2 receptor affinity.
|
Brain Res
|
1987
|
0.81
|
|
28
|
Increased responsiveness of dopamine to atypical, but not typical antipsychotics in the medial prefrontal cortex of rats reared in isolation.
|
Psychopharmacology (Berl)
|
2001
|
0.81
|
|
29
|
Comparative chemical structure and pharmacokinetics of MRI contrast agents.
|
Invest Radiol
|
1988
|
0.81
|
|
30
|
Chronic mild stress-induced reductions in saccharin intake depend upon feeding status.
|
J Psychopharmacol
|
1997
|
0.79
|
|
31
|
The selective 5-HT1B receptor inverse agonist SB-224289, potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
|
Ann N Y Acad Sci
|
1998
|
0.78
|
|
32
|
The effects of central catecholamine depletions on spatial learning in rats.
|
Behav Brain Res
|
1983
|
0.78
|
|
33
|
Anxiolytic profile of ropinirole in the rat, mouse and common marmoset.
|
Psychopharmacology (Berl)
|
2000
|
0.78
|
|
34
|
Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze.
|
Psychopharmacology (Berl)
|
1998
|
0.78
|
|
35
|
Clozapine enhances breakpoint in common marmosets responding on a progressive ratio schedule.
|
Psychopharmacology (Berl)
|
2001
|
0.78
|
|
36
|
The effect of SB-236057-A, a selective 5-HT1B receptor inverse agonist, on in vivo extracellular 5-HT levels in the freely-moving guinea-pig.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2000
|
0.78
|
|
37
|
The effect of SB-269970, a 5-HT(7) receptor antagonist, on 5-HT release from serotonergic terminals and cell bodies.
|
Br J Pharmacol
|
2001
|
0.78
|
|
38
|
Short-term individual housing induced social deficits in female Mongolian gerbils: attenuation by chronic but not acute imipramine.
|
Neuropharmacology
|
2012
|
0.77
|
|
39
|
5-HT 1D receptors mediate SKF 99101H-induced hypothermia in the guinea pig.
|
J Psychopharmacol
|
1995
|
0.77
|
|
40
|
Influence of peptide CRF receptor antagonists upon the behavioural effects of human/rat CRF.
|
Eur J Pharmacol
|
1999
|
0.77
|
|
41
|
Acute and chronic administration of the selective D(3) receptor antagonist SB-277011-A alters activity of midbrain dopamine neurons in rats: an in vivo electrophysiological study.
|
J Pharmacol Exp Ther
|
2000
|
0.76
|
|
42
|
Effects of granisetron, a 5-HT3 receptor antagonist, on morphine-induced potentiation of brain stimulation reward.
|
Eur J Pharmacol
|
1995
|
0.76
|
|
43
|
The 5 -HT3 receptor antagonists, granisetron and ondansetron, do not affect cocaine-induced shifts in intra-cranial self-stimulation thresholds.
|
J Psychopharmacol
|
1995
|
0.75
|
|
44
|
Human thyrotropin radiolabel: specific activity, zero binding, and stability.
|
Clin Chem
|
1983
|
0.75
|
|
45
|
Design and synthesis of 2-naphthoate esters as selective dopamine D4 antagonists.
|
J Med Chem
|
1996
|
0.75
|
|
46
|
Prekallikrein activation, C1 esterase inhibitor, and factor XII as predictors of adverse reaction to contrast media. A prospective study.
|
Invest Radiol
|
1987
|
0.75
|
|
47
|
A computer-controlled apparatus for measuring and analysing myoclonic jerk activity in guinea pigs.
|
J Neurosci Methods
|
1996
|
0.75
|
|
48
|
A predictive test for adverse reactions to contrast media. Preliminary results.
|
Invest Radiol
|
1988
|
0.75
|
|
49
|
Post-training vasopressin injections may facilitate or delay shuttle-box avoidance extinction.
|
Behav Neural Biol
|
1982
|
0.75
|
|
50
|
The effects of endorphins on cardiac responses during an emotional stress.
|
Physiol Behav
|
1983
|
0.75
|
|
51
|
Effects of lysine vasopressin and response prevention on avoidance responding in extinction.
|
Behav Neural Biol
|
1982
|
0.75
|
|
52
|
Hippocampal electrical activity and gamma-aminobutyrate metabolism in brain tissue following administration of homocysteine.
|
J Neurochem
|
1983
|
0.75
|
|
53
|
Morphological, neurochemical, and behavioral studies on serotonergic denervation and graft-induced reinnervation of the rat hippocampus.
|
Neuroscience
|
1991
|
0.75
|
|
54
|
Vasopressin prolongs bradycardiac response during orientation.
|
Behav Neural Biol
|
1984
|
0.75
|
|
55
|
Cholinergic stimulation of drinking from the lateral hypothalamus: indications for M2 muscarinic receptor mediation.
|
Pharmacol Biochem Behav
|
1987
|
0.75
|
|
56
|
Lack of task specificity and absence of posttraining effects of atropine on learning.
|
Behav Neurosci
|
1986
|
0.75
|
|
57
|
Insulin and oral antidiabetic drugs.
|
Int Anesthesiol Clin
|
1975
|
0.75
|
|
58
|
Lysine vasopressin fails to alter (3H)-noradrenaline uptake or release from hippocampal tissue in vitro.
|
Life Sci
|
1983
|
0.75
|
|
59
|
Effects of fluoxetine on social behaviour and plasma corticosteroid levels in female Mongolian gerbils.
|
Behav Pharmacol
|
2003
|
0.75
|
|
60
|
Post training lysine-vasopressin injections increase conditioned suppression in rats.
|
Physiol Behav
|
1983
|
0.75
|