Published in Dev Biol on October 26, 2006
Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro. Biol Reprod (2007) 1.94
Malformation syndromes caused by disorders of cholesterol synthesis. J Lipid Res (2010) 1.88
Genotype-phenotype analysis in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency. J Clin Endocrinol Metab (2011) 1.67
Human cytochromes P450 in health and disease. Philos Trans R Soc Lond B Biol Sci (2013) 1.36
How degrading: Cyp26s in hindbrain development. Dev Dyn (2008) 1.14
Craniosynostosis and multiple skeletal anomalies in humans and zebrafish result from a defect in the localized degradation of retinoic acid. Am J Hum Genet (2011) 1.12
A clinical and experimental overview of sirenomelia: insight into the mechanisms of congenital limb malformations. Dis Model Mech (2011) 1.03
Cholesterol metabolism: the main pathway acting downstream of cytochrome P450 oxidoreductase in skeletal development of the limb. Mol Cell Biol (2009) 1.03
A Genetic-Pathophysiological Framework for Craniosynostosis. Am J Hum Genet (2015) 1.02
Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency. Eur J Endocrinol (2010) 0.99
The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development. FASEB J (2013) 0.98
Retinoic acid: a key player in immunity. Biofactors (2010) 0.95
Multiple cytochrome P-450 genes are concomitantly regulated by vitamin A under steady-state conditions and by retinoic acid during hepatic first-pass metabolism. Physiol Genomics (2010) 0.93
Generation of a mouse model with a reversible hypomorphic cytochrome P450 reductase gene: utility for tissue-specific rescue of the reductase expression, and insights from a resultant mouse model with global suppression of P450 reductase expression in extrahepatic tissues. J Pharmacol Exp Ther (2010) 0.86
Mesodermal retinoic acid signaling regulates endothelial cell coalescence in caudal pharyngeal arch artery vasculogenesis. Dev Biol (2011) 0.85
The rhythm of retinoids in the brain. J Neurochem (2013) 0.84
Pubertal presentation in seven patients with congenital adrenal hyperplasia due to P450 oxidoreductase deficiency. J Clin Endocrinol Metab (2010) 0.83
Sirenomelia phenotype in bmp7;shh compound mutants: a novel experimental model for studies of caudal body malformations. PLoS One (2012) 0.83
Identification of six novel P450 oxidoreductase missense variants in Ashkenazi and Moroccan Jewish populations. Pharmacogenomics (2012) 0.81
NADPH-cytochrome P450 reductase is regulated by all-trans retinoic acid and by 1,25-dihydroxyvitamin D3 in human acute myeloid leukemia cells. PLoS One (2014) 0.78
Genetic advances in craniosynostosis. Am J Med Genet A (2017) 0.76
The P450 oxidoreductase, RedA, controls development beyond the mound stage in Dictyostelium discoideum. BMC Dev Biol (2008) 0.75
Birth defects associated with perturbations in preimplantation, gastrulation, and axis extension: from conjoined twinning to caudal dysgenesis. Wiley Interdiscip Rev Dev Biol (2012) 0.75
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol (2011) 4.84
Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1. J Biol Chem (2002) 3.92
Gene expression regulation by retinoic acid. J Lipid Res (2002) 3.62
Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer. Proc Natl Acad Sci U S A (2002) 3.57
Retinoic acid in development: towards an integrated view. Nat Rev Genet (2008) 3.24
Is serum gamma glutamyltransferase a marker of oxidative stress? Free Radic Res (2004) 3.07
Identification and characterization of rod-derived cone viability factor. Nat Genet (2004) 2.63
Retinoic acid signalling during development. Development (2012) 2.47
A comprehensive collection of chicken cDNAs. Curr Biol (2002) 2.47
Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development. Nat Genet (2002) 2.45
In vivo imaging of NF-kappa B activity. J Immunol (2002) 2.36
A systematic screening of total antioxidants in dietary plants. J Nutr (2002) 2.34
Oxidative stress markers and antioxidant status after oral iron supplementation to very low birth weight infants. J Pediatr (2007) 2.25
Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification. Nat Genet (2005) 2.24
Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response. J Immunol (2004) 2.13
Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice. Dev Biol (2005) 2.13
Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase. J Biol Chem (2003) 2.07
Several culinary and medicinal herbs are important sources of dietary antioxidants. J Nutr (2003) 1.98
Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly. Atherosclerosis (2009) 1.97
Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development. J Cell Sci (2008) 1.89
A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. Carcinogenesis (2002) 1.89
Content of redox-active compounds (ie, antioxidants) in foods consumed in the United States. Am J Clin Nutr (2006) 1.86
A robust system for RNA interference in the chicken using a modified microRNA operon. Dev Biol (2006) 1.83
CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis. Gene Expr Patterns (2004) 1.83
Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines. Cancer Res (2004) 1.75
Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation. Nat Immunol (2009) 1.71
The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide. Nutr J (2010) 1.70
Integration of growth and specification in chick wing digit-patterning. Nature (2008) 1.70
Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse. Mech Dev (2002) 1.67
Retinoic acid controls the bilateral symmetry of somite formation in the mouse embryo. Science (2005) 1.66
Consumption of coffee is associated with reduced risk of death attributed to inflammatory and cardiovascular diseases in the Iowa Women's Health Study. Am J Clin Nutr (2006) 1.64
Plasma vitamin D and mortality in older men: a community-based prospective cohort study. Am J Clin Nutr (2010) 1.64
miRNeye: a microRNA expression atlas of the mouse eye. BMC Genomics (2010) 1.59
The chicken as a model for large-scale analysis of vertebrate gene function. Nat Rev Genet (2003) 1.57
Intakes of antioxidants in coffee, wine, and vegetables are correlated with plasma carotenoids in humans. J Nutr (2004) 1.57
Organisation of human ER-exit sites: requirements for the localisation of Sec16 to transitional ER. J Cell Sci (2009) 1.56
Interactions between FGF and Wnt signals and Tbx3 gene expression in mammary gland initiation in mouse embryos. J Anat (2004) 1.55
Identification of novel roles of the cytochrome p450 system in early embryogenesis: effects on vasculogenesis and retinoic Acid homeostasis. Mol Cell Biol (2003) 1.54
Embryonic retinoic acid synthesis is required for forelimb growth and anteroposterior patterning in the mouse. Development (2002) 1.52
Generation of a stable antioxidant response element-driven reporter gene cell line and its use to show redox-dependent activation of nrf2 by cancer chemotherapeutic agents. Cancer Res (2006) 1.51
Expression of limb initiation genes and clues to the morphological diversification of threespine stickleback. Curr Biol (2003) 1.46
The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation. Development (2009) 1.45
Growing models of vertebrate limb development. Development (2009) 1.45
Whole-grain consumption is associated with a reduced risk of noncardiovascular, noncancer death attributed to inflammatory diseases in the Iowa Women's Health Study. Am J Clin Nutr (2007) 1.45
Plasma 25-hydroxyvitamin D levels and fracture risk in a community-based cohort of elderly men in Sweden. J Clin Endocrinol Metab (2010) 1.43
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos. Curr Biol (2003) 1.42
The chicken talpid3 gene encodes a novel protein essential for Hedgehog signaling. Genes Dev (2006) 1.42
A retinoic acid-dependent checkpoint in the development of CD4+ T cell-mediated immunity. J Exp Med (2011) 1.41
Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha. Proc Natl Acad Sci U S A (2007) 1.40
Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags. Genome Res (2004) 1.38
[Biological effects of vitamin K and concentration of vitamin K in Norwegian food]. Tidsskr Nor Laegeforen (2004) 1.38
Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives. Dev Biol (2006) 1.37
Polyphenols and glutathione synthesis regulation. Am J Clin Nutr (2005) 1.36
In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med (2009) 1.35
Fgf signaling controls the number of phalanges and tip formation in developing digits. Curr Biol (2003) 1.35
The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system. Development (2003) 1.34
Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis. Mech Dev (2002) 1.31
AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line. J Biol Chem (2004) 1.30
Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice. Proc Natl Acad Sci U S A (2003) 1.30
Long-range conserved non-coding SHOX sequences regulate expression in developing chicken limb and are associated with short stature phenotypes in human patients. Hum Mol Genet (2007) 1.29
Cyp26C1 encodes a novel retinoic acid-metabolizing enzyme expressed in the hindbrain, inner ear, first branchial arch and tooth buds during murine development. Gene Expr Patterns (2003) 1.28
Insights into bird wing evolution and digit specification from polarizing region fate maps. Nat Commun (2011) 1.28
Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi. J Biol Chem (2003) 1.26
PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity. Drug Metab Rev (2006) 1.26
Bilberry juice modulates plasma concentration of NF-kappaB related inflammatory markers in subjects at increased risk of CVD. Eur J Nutr (2010) 1.24
Distinct roles for retinoic acid receptors alpha and beta in early lung morphogenesis. Dev Biol (2006) 1.24
Vitamin C and E supplementation hampers cellular adaptation to endurance training in humans: a double-blind, randomised, controlled trial. J Physiol (2014) 1.23
Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism. Br J Clin Pharmacol (2003) 1.23
Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL. FASEB J (2009) 1.22
A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response. J Clin Invest (2008) 1.22
Integrating technologies for comparing 3D gene expression domains in the developing chick limb. Dev Biol (2008) 1.22
Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice. Carcinogenesis (2008) 1.22
Interactions between Shh, Sostdc1 and Wnt signaling and a new feedback loop for spatial patterning of the teeth. Development (2011) 1.21
Flavonoids increase the intracellular glutathione level by transactivation of the gamma-glutamylcysteine synthetase catalytical subunit promoter. Free Radic Biol Med (2002) 1.20
MyD88 and retinoic acid signaling pathways interact to modulate gastrointestinal activities of dendritic cells. Gastroenterology (2011) 1.19
Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen. Am J Physiol Lung Cell Mol Physiol (2007) 1.19
Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer. Int J Cancer (2004) 1.18
Enhancer elements upstream of the SHOX gene are active in the developing limb. Eur J Hum Genet (2009) 1.17
Retinaldehyde dehydrogenase 2 and Hoxc8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons and the correct distribution of Islet1+ motoneurons. Development (2005) 1.17
Glutathione transferase pi plays a critical role in the development of lung carcinogenesis following exposure to tobacco-related carcinogens and urethane. Cancer Res (2007) 1.17
Fin development in a cartilaginous fish and the origin of vertebrate limbs. Nature (2002) 1.16
Molecular interactions between Tbx3 and Bmp4 and a model for dorsoventral positioning of mammary gland development. Proc Natl Acad Sci U S A (2006) 1.16
Role of hepatic cytochrome p450s in the pharmacokinetics and toxicity of cyclophosphamide: studies with the hepatic cytochrome p450 reductase null mouse. Cancer Res (2005) 1.15
Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain. EMBO J (2003) 1.15
Mutations of APC, K-ras, and p53 are associated with specific chromosomal aberrations in colorectal adenocarcinomas. Cancer Res (2003) 1.14
Retinoids control anterior and dorsal properties in the developing forebrain. Dev Biol (2006) 1.13
Anthocyanins inhibit nuclear factor-kappaB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults. J Nutr (2007) 1.13
Direct crossregulation between retinoic acid receptor {beta} and Hox genes during hindbrain segmentation. Development (2005) 1.13
Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway. Biochem J (2009) 1.13
Laminar shear stress acts as a switch to regulate divergent functions of NF-kappaB in endothelial cells. FASEB J (2007) 1.13
GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism. Proc Natl Acad Sci U S A (2007) 1.11
Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines. Mol Pharmacol (2011) 1.10