In vitro antileishmanial activity of Aloe vera leaf exudate: a potential herbal therapy in leishmaniasis.

PubWeight™: 0.93‹?›

🔗 View Article (PMID 17146713)

Published in Glycoconj J on January 01, 2007

Authors

Avijit Dutta1, Goutam Mandal, Chitra Mandal, Mitali Chatterjee

Author Affiliations

1: Department of Immunobiology, Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata 700 032, India.

Articles cited by this

Leishmaniasis: current situation and new perspectives. Comp Immunol Microbiol Infect Dis (2004) 11.90

Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda. Lancet Infect Dis (2002) 7.17

Drug resistance in Indian visceral leishmaniasis. Trop Med Int Health (2001) 3.08

Aloe vera leaf gel: a review update. J Ethnopharmacol (1999) 2.72

Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics. Int J Parasitol (2004) 1.84

Axenically cultured amastigote forms as an in vitro model for investigation of antileishmanial agents. Antimicrob Agents Chemother (1997) 1.83

Production of nitric oxide and superoxide by activated macrophages and killing of Leishmania major. Eur J Immunol (1994) 1.82

Natural products as antiparasitic drugs. Parasitol Res (2003) 1.66

Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug. Antimicrob Agents Chemother (2003) 1.45

Characterization of developmentally-regulated activities in axenic amastigotes of Leishmania donovani. Mol Biochem Parasitol (1998) 1.38

Immune response to Leishmania infection. Indian J Med Res (2004) 1.36

Development of a modified MTT assay for screening antimonial resistant field isolates of Indian visceral leishmaniasis. Parasitol Int (2005) 1.34

Antimonial-induced increase in intracellular Ca2+ through non-selective cation channels in the host and the parasite is responsible for apoptosis of intracellular Leishmania donovani amastigotes. J Biol Chem (2003) 1.32

Recent advances in the fight against leishmaniasis with natural products. Parasite (1999) 1.22

In vitro susceptibilities of Shigella flexneri and Streptococcus pyogenes to inner gel of Aloe barbadensis Miller. Antimicrob Agents Chemother (2003) 1.07

An automated micro-fluorometric assay for monitoring oxidative burst activity of phagocytes. J Immunol Methods (1993) 1.00

A cluster of cases of severe cardiotoxicity among kala-azar patients treated with a high-osmolarity lot of sodium antimony gluconate. Am J Trop Med Hyg (1998) 0.94

Antifungal effects of different plant extracts and their major components of selected aloe species. Phytother Res (1999) 0.77

Articles by these authors

Molecular and morphological heterogeneity of neural precursors in the mouse neocortical proliferative zones. J Neurosci (2006) 2.49

A novel copper chelate modulates tumor associated macrophages to promote anti-tumor response of T cells. PLoS One (2009) 1.45

Visceral leishmaniasis - current therapeutic modalities. Indian J Med Res (2006) 1.45

Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade. Apoptosis (2008) 1.44

Role of ABC transporter MRPA, gamma-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani. J Antimicrob Chemother (2007) 1.38

Development of a modified MTT assay for screening antimonial resistant field isolates of Indian visceral leishmaniasis. Parasitol Int (2005) 1.34

Plant derived therapeutics for the treatment of Leishmaniasis. Phytomedicine (2011) 1.27

Artemisinin triggers induction of cell-cycle arrest and apoptosis in Leishmania donovani promastigotes. J Med Microbiol (2007) 1.27

Natural products: promising resources for cancer drug discovery. Anticancer Agents Med Chem (2012) 1.23

Post-kala-azar dermal leishmaniasis--an overview. Int J Dermatol (2010) 1.15

Assessing aquaglyceroporin gene status and expression profile in antimony-susceptible and -resistant clinical isolates of Leishmania donovani from India. J Antimicrob Chemother (2010) 1.14

Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase. Mol Cancer (2010) 1.11

Oxidative stress as a potential biomarker for determining disease activity in patients with rheumatoid arthritis. Free Radic Res (2012) 1.09

Sialic acids acquired by Pseudomonas aeruginosa are involved in reduced complement deposition and siglec mediated host-cell recognition. FEBS Lett (2009) 1.08

Increased levels of interleukin-10 and IgG3 are hallmarks of Indian post-kala-azar dermal leishmaniasis. J Infect Dis (2008) 1.06

Elevated levels of tryparedoxin peroxidase in antimony unresponsive Leishmania donovani field isolates. Mol Biochem Parasitol (2010) 1.05

Chronic arsenic exposure impairs macrophage functions in the exposed individuals. J Clin Immunol (2009) 1.03

Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways. Biochem Pharmacol (2009) 1.02

Functionality of drug efflux pumps in antimonial resistant Leishmania donovani field isolates. Indian J Biochem Biophys (2009) 1.02

Intracellular GSH depletion triggered mitochondrial Bax translocation to accomplish resveratrol-induced apoptosis in the U937 cell line. J Pharmacol Exp Ther (2010) 1.02

Miltefosine effectively modulates the cytokine milieu in Indian post kala-azar dermal leishmaniasis. J Infect Dis (2011) 0.99

Arsenic induced apoptosis in malignant melanoma cells is enhanced by menadione through ROS generation, p38 signaling and p53 activation. Apoptosis (2009) 0.98

An ethanolic extract of leaves of Piper betle (Paan) Linn mediates its antileishmanial activity via apoptosis. Parasitol Res (2008) 0.97

Aloe vera leaf exudate induces a caspase-independent cell death in Leishmania donovani promastigotes. J Med Microbiol (2007) 0.95

Development of a semi-automated colorimetric assay for screening anti-leishmanial agents. J Microbiol Methods (2005) 0.95

High-throughput screening of amastigotes of Leishmania donovani clinical isolates against drugs using a colorimetric beta-lactamase assay. Indian J Exp Biol (2009) 0.94

Sialoglycoproteins adsorbed by Pseudomonas aeruginosa facilitate their survival by impeding neutrophil extracellular trap through siglec-9. J Leukoc Biol (2012) 0.93

Role of C-reactive protein in complement-mediated hemolysis in Malaria. Glycoconj J (2006) 0.93

Variable degree of alternative complement pathway-mediated hemolysis in Indian visceral leishmaniasis induced by differential expression of 9-O-acetylated sialoglycans. J Infect Dis (2004) 0.93

Anti-inflammatory effect of allylpyrocatechol in LPS-induced macrophages is mediated by suppression of iNOS and COX-2 via the NF-kappaB pathway. Int Immunopharmacol (2008) 0.93

Racemoside A, an anti-leishmanial, water-soluble, natural steroidal saponin, induces programmed cell death in Leishmania donovani. J Med Microbiol (2007) 0.93

Induction of glycosylation in human C-reactive protein under different pathological conditions. Biochem J (2003) 0.92

Monitoring of intracellular nitric oxide in leishmaniasis: its applicability in patients with visceral leishmaniasis. Cytometry A (2011) 0.92

Role of aquaglyceroporin (AQP1) gene and drug uptake in antimony-resistant clinical isolates of Leishmania donovani. Am J Trop Med Hyg (2008) 0.92

Correlation of oxidant status with oxidative tissue damage in patients with rheumatoid arthritis. Clin Rheumatol (2014) 0.92

Attenuation of oxidative stress by allylpyrocatechol in synovial cellular infiltrate of patients with Rheumatoid Arthritis. Free Radic Res (2011) 0.91

Detection and characterization of a sialoglycosylated bacterial ABC-type phosphate transporter protein from patients with visceral leishmaniasis. Glycoconj J (2009) 0.91

Arsenic-induced mitochondrial instability leading to programmed cell death in the exposed individuals. Toxicology (2008) 0.91

Efficacy of artemisinin in experimental visceral leishmaniasis. Int J Antimicrob Agents (2010) 0.91

Four new dinuclear Cu(ii) hydrazone complexes using various organic spacers: syntheses, crystal structures, DNA binding and cleavage studies and selective cell inhibitory effect towards leukemic and normal lymphocytes. Dalton Trans (2009) 0.90

Enhanced lesional Foxp3 expression and peripheral anergic lymphocytes indicate a role for regulatory T cells in Indian post-kala-azar dermal leishmaniasis. J Invest Dermatol (2009) 0.90

Flow cytometric determination of intracellular non-protein thiols in Leishmania promastigotes using 5-chloromethyl fluorescein diacetate. Exp Parasitol (2009) 0.90

Antibodies directed against O-acetylated sialoglycoconjugates accelerate complement activation in Leishmania donovani promastigotes. J Infect Dis (2004) 0.89

Elevated mRNA level of hST6Gal I and hST3Gal V positively correlates with the high risk of pediatric acute leukemia. Leuk Res (2009) 0.89

In vitro and in vivo activity of Aloe vera leaf exudate in experimental visceral leishmaniasis. Parasitol Res (2008) 0.89

O-acetylation of GD3 prevents its apoptotic effect and promotes survival of lymphoblasts in childhood acute lymphoblastic leukaemia. J Cell Biochem (2008) 0.89

Leishmania cell surface prohibitin: role in host-parasite interaction. Cell Microbiol (2009) 0.88

Rapid induction of IgE responses to a worm cysteine protease during murine pre-patent schistosome infection. BMC Immunol (2010) 0.88

Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinoma in vitro and in vivo. Int J Cancer (2012) 0.88

Case series of misdiagnosis with rK39 strip test in Indian leishmaniasis. Am J Trop Med Hyg (2011) 0.88

Resveratrol induces apoptosis in K562 (chronic myelogenous leukemia) cells by targeting a key survival protein, heat shock protein 70. Cancer Sci (2008) 0.87

Bak compensated for Bax in p53-null cells to release cytochrome c for the initiation of mitochondrial signaling during Withanolide D-induced apoptosis. PLoS One (2012) 0.87

Myeloid derived suppressor cells (MDSCs) can induce the generation of Th17 response from naïve CD4+ T cells. Immunobiology (2012) 0.87

An ethanol extract of Piper betle Linn. mediates its anti-inflammatory activity via down-regulation of nitric oxide. J Pharm Pharmacol (2007) 0.87

Coinfection of Leptomonas seymouri and Leishmania donovani in Indian leishmaniasis. J Clin Microbiol (2012) 0.87

The role of alanine 163 in solute permeability of Leishmania major aquaglyceroporin LmAQP1. Mol Biochem Parasitol (2010) 0.87

The antioxidant activity of allylpyrocatechol is mediated via decreased generation of free radicals along with escalation of antioxidant mechanisms. Phytother Res (2012) 0.87

Synthesis, cytotoxicity, and structure-activity relationship (SAR) studies of andrographolide analogues as anti-cancer agent. Bioorg Med Chem Lett (2010) 0.86

Arsenic-induced cell proliferation is associated with enhanced ROS generation, Erk signaling and CyclinA expression. Toxicol Lett (2010) 0.86

Identification and characterization of adsorbed serum sialoglycans on Leishmania donovani promastigotes. Glycobiology (2002) 0.86

Methylglyoxal induced activation of murine peritoneal macrophages and surface markers of T lymphocytes in sarcoma-180 bearing mice: involvement of MAP kinase, NF-kappa beta signal transduction pathway. Mol Immunol (2009) 0.86

Targeting mitochondrial cell death pathway to overcome drug resistance with a newly developed iron chelate. PLoS One (2010) 0.86

High level of sialate-O-acetyltransferase activity in lymphoblasts of childhood acute lymphoblastic leukaemia (ALL): enzyme characterization and correlation with disease status. Glycoconj J (2008) 0.86

Sialoglycans in protozoal diseases: their detection, modes of acquisition and emerging biological roles. Glycoconj J (2004) 0.85

Berberine chloride mediates its anti-leishmanial activity via differential regulation of the mitogen activated protein kinase pathway in macrophages. PLoS One (2011) 0.85

Chemotypical variations in Withania somnifera lead to differentially modulated immune response in BALB/c mice. Vaccine (2011) 0.85

High yielding recombinant Staphylokinase in bacterial expression system--cloning, expression, purification and activity studies. Protein Expr Purif (2008) 0.85

Differential expression of 9-O-acetylated sialoglycoconjugates on leukemic blasts: a potential tool for long-term monitoring of children with acute lymphoblastic leukemia. Int J Cancer (2004) 0.84

Berberine chloride causes a caspase-independent, apoptotic-like death in Leishmania donovani promastigotes. Free Radic Res (2009) 0.84

Immunomodulation by chemotherapeutic agents against Leishmaniasis. Int Immunopharmacol (2011) 0.84

Anti-inflammatory effect of a methanolic extract of leaves of Dregea volubilis. J Ethnopharmacol (2010) 0.84

Mahanine synergistically enhances cytotoxicity of 5-fluorouracil through ROS-mediated activation of PTEN and p53/p73 in colon carcinoma. Apoptosis (2014) 0.84

Targeting the mitochondrial pathway to induce apoptosis/necrosis through ROS by a newly developed Schiff's base to overcome MDR in cancer. Biochimie (2011) 0.83

Coupling G2/M arrest to the Wnt/β-catenin pathway restrains pancreatic adenocarcinoma. Endocr Relat Cancer (2014) 0.83

Purification, characterization of O-acetylated sialoglycoconjugates-specific IgM, and development of an enzyme-linked immunosorbent assay for diagnosis and follow-up of indian visceral leishmaniasis patients. Diagn Microbiol Infect Dis (2004) 0.83

Glycobiology of Leishmania donovani. Indian J Med Res (2006) 0.83

Over expression and analysis of O-glycosylated recombinant human granulocyte colony stimulating factor in Pichia pastoris using Agilent 2100 Bioanalyzer. J Biotechnol (2009) 0.83

Evaluation of serological markers to monitor the disease status of Indian post kala-azar dermal leishmaniasis. Trans R Soc Trop Med Hyg (2012) 0.83

Identification and quantification of the active component quercetin 3-O-rutinoside from Barringtonia racemosa, targets mitochondrial apoptotic pathway in acute lymphoblastic leukemia. J Asian Nat Prod Res (2010) 0.83

9-O-acetylated GD3 triggers programmed cell death in mature erythrocytes. Biochem Biophys Res Commun (2007) 0.83

Calpain and caspase orchestrated death signal to accomplish apoptosis induced by resveratrol and its novel analog hydroxystilbene-1 [correction of hydroxstilbene-1] in cancer cells. J Pharmacol Exp Ther (2010) 0.83

High-level expression of non-glycosylated and active staphylokinase from Pichia pastoris. Biotechnol Lett (2009) 0.83

Antibodies against 9-O-acetylated sialoglycans: a potent marker to monitor clinical status in childhood acute lymphoblastic leukemia. Clin Biochem (2004) 0.82

An orally effective dihydropyrimidone (DHPM) analogue induces apoptosis-like cell death in clinical isolates of Leishmania donovani overexpressing pteridine reductase 1. Parasitol Res (2009) 0.82

Down regulation of membrane-bound Neu3 constitutes a new potential marker for childhood acute lymphoblastic leukemia and induces apoptosis suppression of neoplastic cells. Int J Cancer (2010) 0.82

Oxidative stress-associated neuroretinal dysfunction and nitrosative stress in diabetic retinopathy. Can J Diabetes (2013) 0.82