Published in Brain Res on December 06, 2006
The comorbidity of autism with the genomic disorders of chromosome 15q11.2-q13. Neurobiol Dis (2008) 1.97
Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder. Behav Brain Res (2007) 1.58
50 years of hurdles and hope in anxiolytic drug discovery. Nat Rev Drug Discov (2013) 1.28
Autism, fever, epigenetics and the locus coeruleus. Brain Res Rev (2008) 1.15
Somatosensory and sensorimotor consequences associated with the heterozygous disruption of the autism candidate gene, Gabrb3. Behav Brain Res (2010) 1.09
Complex control of GABA(A) receptor subunit mRNA expression: variation, covariation, and genetic regulation. PLoS One (2012) 1.04
The neurobiology of mouse models syntenic to human chromosome 15q. J Neurodev Disord (2011) 0.85
Age-Dependent Changes in the Inflammatory Nociceptive Behavior of Mice. Int J Mol Sci (2015) 0.78
Deletion of PREPl causes growth impairment and hypotonia in mice. PLoS One (2014) 0.77
An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance. Annu Rev Neurosci (2005) 9.32
The locus coeruleus-noradrenergic system: modulation of behavioral state and state-dependent cognitive processes. Brain Res Brain Res Rev (2003) 6.09
A clinicopathological study of autism. Brain (1998) 3.49
Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proc Natl Acad Sci U S A (1998) 2.54
Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes. Am J Hum Genet (2003) 2.23
Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proc Natl Acad Sci U S A (1997) 2.16
Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome. J Neurosci (1998) 2.09
Autism: a medical primer. Am Fam Physician (2002) 2.06
Evaluation of marble-burying behavior as a model of anxiety. Pharmacol Biochem Behav (1991) 2.04
Association between a GABRB3 polymorphism and autism. Mol Psychiatry (2002) 2.00
Noradrenergic mechanisms in stress and anxiety: I. Preclinical studies. Synapse (1996) 1.97
Factors controlling measures of anxiety and responses to novelty in the mouse. Behav Brain Res (2001) 1.89
Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology. Prog Brain Res (1991) 1.88
Linkage-disequilibrium mapping of autistic disorder, with 15q11-13 markers. Am J Hum Genet (1998) 1.87
Disruption of GABA(A) receptors on GABAergic interneurons leads to increased oscillatory power in the olfactory bulb network. J Neurophysiol (2001) 1.62
Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and partial lethality and provides evidence for a gene contributing to Prader-Willi syndrome. Hum Mol Genet (1999) 1.61
The contribution of neuropathologic studies to the understanding of autism. Neurol Clin (1993) 1.57
theta, a novel gamma-aminobutyric acid type A receptor subunit. Proc Natl Acad Sci U S A (1999) 1.54
Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice. Neurosci Lett (2000) 1.51
The Mouse Defense Test Battery: pharmacological and behavioral assays for anxiety and panic. Eur J Pharmacol (2003) 1.44
Activation of locus coeruleus enhances the responses of olfactory bulb mitral cells to weak olfactory nerve input. J Neurosci (1996) 1.31
Noradrenaline systems in the hypothalamus, amygdala and locus coeruleus are involved in the provocation of anxiety: basic studies. Eur J Pharmacol (2000) 1.30
Noradrenergic function in panic anxiety. Effects of yohimbine in healthy subjects and patients with agoraphobia and panic disorder. Arch Gen Psychiatry (1984) 1.28
Effects of 5-HT uptake inhibitors, agonists and antagonists on the burying of harmless objects by mice; a putative test for anxiolytic agents. Br J Pharmacol (1991) 1.28
Anxiety, motor activation, and maternal-infant interactions in 5HT1B knockout mice. Behav Neurosci (1999) 1.20
Numerous GABAergic afferents to locus ceruleus in the pericerulear dendritic zone: possible interneuronal pool. J Neurosci (2004) 1.20
5-HT1A-receptor subtype mediates the effect of fluvoxamine, a selective serotonin reuptake inhibitor, on marble-burying behavior in mice. Jpn J Pharmacol (1995) 1.15
Influence of social isolation, gender, strain, and prior novelty on plus-maze behaviour in mice. Physiol Behav (1993) 1.12
Three probands with autistic disorder and isodicentric chromosome 15. Am J Med Genet (2000) 1.12
Prenatal ontogeny of the GABAergic system in the rat brain: an immunocytochemical study. Neuroscience (1986) 1.11
Dendrites of locus coeruleus neurons extend preferentially into two pericoerulear zones. J Comp Neurol (1996) 1.08
Analysis of the marble burying response: marbles serve to measure digging rather than evoke burying. Behav Pharmacol (1995) 1.07
Mouse models for autism: report from a meeting. Mamm Genome (2001) 1.07
GABRB3 gene deficient mice: a potential model of autism spectrum disorder. Int Rev Neurobiol (2005) 1.07
Increased and decreased muscle tone with orexin (hypocretin) microinjections in the locus coeruleus and pontine inhibitory area. J Neurophysiol (2001) 1.01
Behavioral abnormalities of Zic1 and Zic2 mutant mice: implications as models for human neurological disorders. Behav Genet (2001) 0.97
Quantitative characterization of ceruleospinal inhibition of nociceptive transmission in the rat. J Neurophysiol (1986) 0.95
Animal models of anxiety: are they suitable for predicting drug action in humans? Pol J Pharmacol (1998) 0.95
Sensory thresholds and the antinociceptive effects of GABA receptor agonists in mice lacking the beta3 subunit of the GABA(A) receptor. Neuroscience (2000) 0.94
An alternative experimental procedure for studying predator-related defensive responses. Neurosci Biobehav Rev (2005) 0.94
Further evidences that risk assessment and object exploration behaviours are useful to evaluate emotional reactivity in rodents. Behav Brain Res (2004) 0.91
The interaction between the locus coeruleus and dorsal raphe nucleus studied with dual-probe microdialysis. Eur J Pharmacol (2002) 0.90
Toward an integrated neurobiology of panic disorder. J Clin Psychiatry (1997) 0.88
Localization of GABAA receptor subunit mRNAs in the rat locus coeruleus. Brain Res Mol Brain Res (1994) 0.88
Airjet and FG-7142-induced Fos expression differs in rats selectively bred for high and low anxiety-related behavior. Neuropharmacology (2006) 0.87
Activity of medial mesopontine units during cataplexy and sleep-waking states in the narcoleptic dog. J Neurosci (1992) 0.87
Behavioral alterations in mice deficient for the extracellular matrix glycoprotein tenascin-R. Behav Brain Res (2003) 0.87
Sleep states and sleep electroencephalographic spectral power in mice lacking the beta 3 subunit of the GABA(A) receptor. Brain Res (2002) 0.86
Chemocytoarchitecture of the rat locus ceruleus. Histol Histopathol (1993) 0.86
Lack of evidence of neuropathology in the locus coeruleus in autism. Acta Neuropathol (2006) 0.85
Animal models with potential applications for screening compounds for the treatment of obsessive-compulsive disorder. Expert Opin Investig Drugs (1997) 0.85
Evidence that the behaviors in the Mouse Defense Test Battery relate to different emotional states: a factor analytic study. Physiol Behav (1996) 0.84
Decreased marble burying behavior in female mice lacking neuromedin-B receptor (NMB-R) implies the involvement of NMB/NMB-R in 5-HT neuron function. Brain Res (2002) 0.84
Digging behavior of ddY mouse. Exp Anim (2000) 0.84
Enhancement of current induced by superfusion of GABA in locus coeruleus neurons by pentobarbital, but not ethanol. Brain Res (1990) 0.83
Behavioral and neurochemical characterization of alpha(2A)-adrenergic receptor knockout mice. Neuroscience (2002) 0.83
Descending control of spinal nociceptive transmission. Actions produced on spinal multireceptive neurones from the nuclei locus coeruleus (LC) and raphe magnus (NRM). Exp Brain Res (1985) 0.82
Tyrosine hydroxylase and serotonin containing cells in embryonic rat rhombencephalon: a whole-mount immunocytochemical study. J Neurosci Res (1988) 0.81
Single unit activity of locus coeruleus neurons in the freely moving cat. II. Conditioning and pharmacologic studies. Brain Res (1986) 0.81
Augmentation of the noradrenergic system in alpha-2 adrenergic receptor deficient mice: anatomical changes associated with enhanced fear memory. Brain Res (2003) 0.80
Panic-like attack induced by microinfusion into the locus coeruleus of antagonists and inverse agonists at GABAA-receptors in rodents. Funct Neurol (1992) 0.80
Effect of 5-[3-[((2S)-1,4-benzodioxan-2-ylmethyl)amino]propoxy]-1,3-benzodioxole HCl (MKC-242), a novel 5-HT1A-receptor agonist, on aggressive behavior and marble burying behavior in mice. Jpn J Pharmacol (1998) 0.78
Increased novelty seeking and decreased harm avoidance in rats showing Type 2-like behaviour following basal forebrain neuronal loss. Alcohol Alcohol (2001) 0.78
Effect of Hypericum perforatum on marble-burying by mice. Phytother Res (2004) 0.77
[A neurologic model of early infantile autism]. No To Hattatsu (1989) 0.77
Neuropharmacological investigations on muscimol, a psychotropic drug extracted from Amanita muscaria. Psychopharmacologia (1969) 0.77
Enhancement of GABA-dependent chloride channel by "in vivo" administration of ethanol. Pharmacol Res (1991) 0.76
Role of the locus coeruleus in the static and dynamic control of posture. Arch Ital Biol (2001) 0.76
Microinjections of GABAergic agents in the locus coeruleus modify the gain of vestibulospinal reflexes in decerebrate cats. Arch Ital Biol (1995) 0.76
Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy. Nat Med (2008) 4.83
Opioid-induced hyperalgesia: a qualitative systematic review. Anesthesiology (2006) 3.81
Aversive and reinforcing opioid effects: a pharmacogenomic twin study. Anesthesiology (2012) 2.85
Pain sensitivity and opioid analgesia: a pharmacogenomic twin study. Pain (2012) 2.44
Colorectal neoplasia in veterans is associated with Barrett's esophagus but not with proton-pump inhibitor or aspirin/NSAID use. Gastrointest Endosc (2006) 2.10
A genetic analysis of opioid-induced hyperalgesia in mice. Anesthesiology (2006) 1.97
Functional imaging of colonic mucosa with a fibered confocal microscope for real-time in vivo pathology. Clin Gastroenterol Hepatol (2007) 1.85
Substance P signaling controls mast cell activation, degranulation, and nociceptive sensitization in a rat fracture model of complex regional pain syndrome. Anesthesiology (2012) 1.64
Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder. Behav Brain Res (2007) 1.58
Patient characteristics associated with opioid versus nonsteroidal anti-inflammatory drug management of chronic low back pain. J Pain (2003) 1.58
No evidence for the development of acute tolerance to analgesic, respiratory depressant and sedative opioid effects in humans. Pain (2009) 1.58
Brain neuroplastic changes accompany anxiety and memory deficits in a model of complex regional pain syndrome. Anesthesiology (2014) 1.56
Peripheral mechanisms of pain and analgesia. Brain Res Rev (2008) 1.55
Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma. Gastroenterology (2006) 1.54
Management of perioperative pain in patients chronically consuming opioids. Reg Anesth Pain Med (2005) 1.34
The role of interleukin-1 in wound biology. Part II: In vivo and human translational studies. Anesth Analg (2010) 1.32
Sex differences in reported pain across 11,000 patients captured in electronic medical records. J Pain (2012) 1.32
Capsaicin-sensitive sensory neurons contribute to the maintenance of trabecular bone integrity. J Bone Miner Res (2004) 1.22
Comparative analgesic and mental effects of increasing plasma concentrations of dexmedetomidine and alfentanil in humans. Anesthesiology (2004) 1.20
The NALP1 inflammasome controls cytokine production and nociception in a rat fracture model of complex regional pain syndrome. Pain (2009) 1.17
The role of interleukin-1 in wound biology. Part I: Murine in silico and in vitro experimental analysis. Anesth Analg (2010) 1.16
Chronic pain and genetic background interact and influence opioid analgesia, tolerance, and physical dependence. Pain (2006) 1.16
Detection of endogenous biomolecules in Barrett's esophagus by Fourier transform infrared spectroscopy. Proc Natl Acad Sci U S A (2007) 1.16
The role of enhanced cutaneous IL-1beta signaling in a rat tibia fracture model of complex regional pain syndrome. Pain (2009) 1.15
Chronic morphine administration enhances nociceptive sensitivity and local cytokine production after incision. Mol Pain (2008) 1.13
Effect of anti-NGF antibodies in a rat tibia fracture model of complex regional pain syndrome type I. Pain (2008) 1.12
A substance P receptor (NK1) antagonist can reverse vascular and nociceptive abnormalities in a rat model of complex regional pain syndrome type II. Pain (2003) 1.11
From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics. Pharmacogenet Genomics (2009) 1.11
Fracture induces keratinocyte activation, proliferation, and expression of pro-nociceptive inflammatory mediators. Pain (2010) 1.09
Somatosensory and sensorimotor consequences associated with the heterozygous disruption of the autism candidate gene, Gabrb3. Behav Brain Res (2010) 1.09
Role of substance P signaling in enhanced nociceptive sensitization and local cytokine production after incision. Pain (2009) 1.07
Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes. Pharmacogenet Genomics (2008) 1.05
Isoflurane and nociception: spinal alpha2A adrenoceptors mediate antinociception while supraspinal alpha1 adrenoceptors mediate pronociception. Anesthesiology (2002) 1.04
Epigenetic regulation of opioid-induced hyperalgesia, dependence, and tolerance in mice. J Pain (2013) 0.98
Neuropeptides contribute to peripheral nociceptive sensitization by regulating interleukin-1β production in keratinocytes. Anesth Analg (2011) 0.96
Alterations in spinal cord gene expression after hindpaw formalin injection. J Neurosci Res (2004) 0.96
miR-203 regulates nociceptive sensitization after incision by controlling phospholipase A2 activating protein expression. Anesthesiology (2012) 0.96
The beta2 adrenergic receptor regulates morphine tolerance and physical dependence. Behav Brain Res (2007) 0.95
A substance P receptor (NK1) antagonist enhances the widespread osteoporotic effects of sciatic nerve section. Bone (2003) 0.95
5-hydroxytryptamine type 3 receptor modulates opioid-induced hyperalgesia and tolerance in mice. Anesthesiology (2011) 0.94
Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala. Neuropsychopharmacology (2004) 0.94
Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit. J Med Chem (2008) 0.90
Extracellular superoxide dismutase is important for hippocampal neurogenesis and preservation of cognitive functions after irradiation. Proc Natl Acad Sci U S A (2012) 0.90
Sympathetic block with botulinum toxin to treat complex regional pain syndrome. Ann Neurol (2009) 0.90
Bone microstructure and its associated genetic variability in 12 inbred mouse strains: microCT study and in silico genome scan. Bone (2007) 0.90
Nociceptive sensitization by complement C5a and C3a in mouse. Pain (2009) 0.89
Opioid pharmacogenomics using a twin study paradigm: methods and procedures for determining familial aggregation and heritability. Twin Res Hum Genet (2010) 0.89
Spinal CK2 regulates nociceptive signaling in models of inflammatory pain. Pain (2005) 0.89
Changes resembling complex regional pain syndrome following surgery and immobilization. J Pain (2013) 0.89
Meperidine exerts agonist activity at the alpha(2B)-adrenoceptor subtype. Anesthesiology (2002) 0.88
Caspase-1 modulates incisional sensitization and inflammation. Anesthesiology (2010) 0.88
Activation profiles of opioid ligands in HEK cells expressing delta opioid receptors. BMC Neurosci (2002) 0.87
Modulation of the NO/CO-cGMP signaling cascade during chronic morphine exposure in mice. Neurosci Lett (2004) 0.87
Pharmacological profiles of opioid ligands at kappa opioid receptors. BMC Pharmacol (2006) 0.87
The complement component C5a receptor mediates pain and inflammation in a postsurgical pain model. Pain (2011) 0.87
Formalin-induced spinal cord calcium/calmodulin-dependent protein kinase II alpha expression is modulated by heme oxygenase in mice. Neurosci Lett (2004) 0.87
Expression genetics identifies spinal mechanisms supporting formalin late phase behaviors. Mol Pain (2010) 0.86
Sleep states and sleep electroencephalographic spectral power in mice lacking the beta 3 subunit of the GABA(A) receptor. Brain Res (2002) 0.86
Epidermal adrenergic signaling contributes to inflammation and pain sensitization in a rat model of complex regional pain syndrome. Pain (2013) 0.86
Epigenetic regulation of spinal CXCR2 signaling in incisional hypersensitivity in mice. Anesthesiology (2013) 0.85
Acute and chronic phases of complex regional pain syndrome in mice are accompanied by distinct transcriptional changes in the spinal cord. Mol Pain (2013) 0.83
Hyperalgesia during opioid abstinence: mediation by glutamate and substance p. Anesth Analg (2002) 0.83
External validation of simulation-based assessments with other performance measures of third-year anesthesiology residents. Simul Healthc (2012) 0.82
Dexmedetomidine fails to cause hyperalgesia after cessation of chronic administration. Anesth Analg (2003) 0.82
Ketamine for managing perioperative pain in opioid-dependent patients with chronic pain: a unique indication? Anesthesiology (2010) 0.81
Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposure. BMC Gastroenterol (2007) 0.80
Roles of Gr-1+ leukocytes in postincisional nociceptive sensitization and inflammation. Anesthesiology (2012) 0.80
Curcumin treatment attenuates pain and enhances functional recovery after incision. Anesth Analg (2014) 0.80
Association of admission hematocrit with 6-month and 1-year mortality in intensive care unit patients. Transfusion (2011) 0.80
Augmentation of the noradrenergic system in alpha-2 adrenergic receptor deficient mice: anatomical changes associated with enhanced fear memory. Brain Res (2003) 0.80
Transcutaneous blood gas CO2 monitoring of induced ventilatory depression in mice. Anesth Analg (2006) 0.80
Spinal cord heme oxygenase participates in glutamate-induced pain-related behaviors. Eur J Pharmacol (2002) 0.79
Integrative approach to pain genetics identifies pain sensitivity loci across diseases. PLoS Comput Biol (2012) 0.79
Understanding our drugs and our diseases. Proc Am Thorac Soc (2006) 0.79
The Netrin-1 receptor DCC is a regulator of maladaptive responses to chronic morphine administration. BMC Genomics (2014) 0.79
Heme oxygenase type 2 participates in the development of chronic inflammatory and neuropathic pain. J Pain (2003) 0.79
Opioid medication management: clinician beware! Anesthesiology (2010) 0.78
Epigenetic regulation of spinal cord gene expression controls opioid-induced hyperalgesia. Mol Pain (2014) 0.78
The antinociceptive effect of transcranial electrostimulation with combined direct and alternating current in freely moving rats. Anesth Analg (2004) 0.78
Understanding methadone metabolism: a foundation for safer use. Anesthesiology (2008) 0.78
Effects of methyl donor diets on incisional pain in mice. PLoS One (2013) 0.77
Sleep quality and the role of sleep medications for veterans with chronic pain. Pain Med (2006) 0.77
Dietary methyl content regulates opioid responses in mice. J Pain Res (2013) 0.77
The role of the extracellular matrix in chronic pain following injury. Pain (2015) 0.76