Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Functional characterization and molecular expression of large neutral amino acid transporter (LAT1) in human prostate cancer cells.
|
Int J Pharm
|
2012
|
2.07
|
2
|
Molecular evidence and functional expression of P-glycoprotein (MDR1) in human and rabbit cornea and corneal epithelial cell lines.
|
Invest Ophthalmol Vis Sci
|
2003
|
1.21
|
3
|
Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor.
|
Int J Pharm
|
2007
|
1.10
|
4
|
Identification of a Na+-dependent cationic and neutral amino acid transporter, B(0,+), in human and rabbit cornea.
|
Mol Pharm
|
2005
|
1.04
|
5
|
Enhanced corneal absorption of erythromycin by modulating P-glycoprotein and MRP mediated efflux with corticosteroids.
|
Pharm Res
|
2008
|
1.01
|
6
|
Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance.
|
Int J Pharm
|
2010
|
1.01
|
7
|
Peptide prodrugs: improved oral absorption of lopinavir, a HIV protease inhibitor.
|
Int J Pharm
|
2008
|
1.00
|
8
|
Molecular expression and functional evidence of a drug efflux pump (BCRP) in human corneal epithelial cells.
|
Curr Eye Res
|
2009
|
1.00
|
9
|
Molecular evidence and functional expression of a novel drug efflux pump (ABCC2) in human corneal epithelium and rabbit cornea and its role in ocular drug efflux.
|
Int J Pharm
|
2006
|
1.00
|
10
|
Identification and functional characterization of a Na+-independent large neutral amino acid transporter, LAT1, in human and rabbit cornea.
|
Invest Ophthalmol Vis Sci
|
2003
|
0.99
|
11
|
Circumventing P-glycoprotein-mediated cellular efflux of quinidine by prodrug derivatization.
|
Mol Pharm
|
2005
|
0.98
|
12
|
In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity.
|
Am J Ther
|
2004
|
0.97
|
13
|
Study of the extent of ocular absorption of acetazolamide from a developed niosomal formulation, by microdialysis sampling of aqueous humor.
|
Int J Pharm
|
2007
|
0.96
|
14
|
Co-administration strategy to enhance brain accumulation of vandetanib by modulating P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp1/Abcg2) mediated efflux with m-TOR inhibitors.
|
Int J Pharm
|
2012
|
0.96
|
15
|
Interaction of ocular hypotensive agents (PGF2 alpha analogs-bimatoprost, latanoprost, and travoprost) with MDR efflux pumps on the rabbit cornea.
|
J Ocul Pharmacol Ther
|
2009
|
0.96
|
16
|
Mechanisms of drug resistance in cancer chemotherapy: coordinated role and regulation of efflux transporters and metabolizing enzymes.
|
Curr Pharm Des
|
2013
|
0.95
|
17
|
Evasion of P-gp mediated cellular efflux and permeability enhancement of HIV-protease inhibitor saquinavir by prodrug modification.
|
Int J Pharm
|
2005
|
0.95
|
18
|
Synthesis, physicochemical properties and antiviral activities of ester prodrugs of ganciclovir.
|
Int J Pharm
|
2005
|
0.94
|
19
|
Functional characterization of sodium-dependent multivitamin transporter in MDCK-MDR1 cells and its utilization as a target for drug delivery.
|
Mol Pharm
|
2006
|
0.93
|
20
|
Controlled delivery of ganciclovir to the retina with drug-loaded Poly(d,L-lactide-co-glycolide) (PLGA) microspheres dispersed in PLGA-PEG-PLGA Gel: a novel intravitreal delivery system for the treatment of cytomegalovirus retinitis.
|
J Ocul Pharmacol Ther
|
2007
|
0.90
|
21
|
Enhanced transport of a novel anti-HIV agent--cosalane and its congeners across human intestinal epithelial (Caco-2) cell monolayers.
|
Int J Pharm
|
2003
|
0.90
|
22
|
Expression of multidrug resistance associated protein 5 (MRP5) on cornea and its role in drug efflux.
|
J Ocul Pharmacol Ther
|
2009
|
0.90
|
23
|
Mechanism of L-ascorbic acid uptake by rabbit corneal epithelial cells: evidence for the involvement of sodium-dependent vitamin C transporter 2.
|
Curr Eye Res
|
2006
|
0.90
|
24
|
Cotransport of macrolide and fluoroquinolones, a beneficial interaction reversing P-glycoprotein efflux.
|
Am J Ther
|
2004
|
0.90
|
25
|
Nanomicellar Topical Aqueous Drop Formulation of Rapamycin for Back-of-the-Eye Delivery.
|
AAPS PharmSciTech
|
2014
|
0.90
|
26
|
Vitreal pharmacokinetics of biotinylated ganciclovir: role of sodium-dependent multivitamin transporter expressed on retina.
|
J Ocul Pharmacol Ther
|
2009
|
0.89
|
27
|
Functional characterization of peptide transporters in MDCKII-MDR1 cell line as a model for oral absorption studies.
|
Int J Pharm
|
2006
|
0.89
|
28
|
Effect of HEPES buffer on the uptake and transport of P-glycoprotein substrates and large neutral amino acids.
|
Mol Pharm
|
2010
|
0.89
|
29
|
Functional differences in nucleoside and nucleobase transporters expressed on the rabbit corneal epithelial cell line (SIRC) and isolated rabbit cornea.
|
AAPS PharmSci
|
2003
|
0.88
|
30
|
Biotin uptake by rabbit corneal epithelial cells: role of sodium-dependent multivitamin transporter (SMVT).
|
Curr Eye Res
|
2006
|
0.88
|
31
|
Differential expression of folate receptor-alpha, sodium-dependent multivitamin transporter, and amino acid transporter (B (0, +)) in human retinoblastoma (Y-79) and retinal pigment epithelial (ARPE-19) cell lines.
|
J Ocul Pharmacol Ther
|
2012
|
0.88
|
32
|
Targeting SVCT for enhanced drug absorption: synthesis and in vitro evaluation of a novel vitamin C conjugated prodrug of saquinavir.
|
Int J Pharm
|
2011
|
0.88
|
33
|
Identification and characterization of a Na+-dependent neutral amino acid transporter, ASCT1, in rabbit corneal epithelial cell culture and rabbit cornea.
|
Curr Eye Res
|
2005
|
0.87
|
34
|
Effect of short term and chronic administration of Sutherlandia frutescens on pharmacokinetics of nevirapine in rats.
|
Int J Pharm
|
2011
|
0.87
|
35
|
Novel nanoparticulate gel formulations of steroids for the treatment of macular edema.
|
J Ocul Pharmacol Ther
|
2010
|
0.86
|
36
|
Novel thermosensitive pentablock copolymers for sustained delivery of proteins in the treatment of posterior segment diseases.
|
Protein Pept Lett
|
2014
|
0.86
|
37
|
Enhanced brain accumulation of pazopanib by modulating P-gp and Bcrp1 mediated efflux with canertinib or erlotinib.
|
Int J Pharm
|
2012
|
0.85
|
38
|
Targeted lipid based drug conjugates: a novel strategy for drug delivery.
|
Int J Pharm
|
2012
|
0.85
|
39
|
Stereoselective evasion of P-glycoprotein, cytochrome P450 3A, and hydrolases by peptide prodrug modification of saquinavir.
|
J Pharm Sci
|
2012
|
0.85
|
40
|
Novel biotinylated lipid prodrugs of acyclovir for the treatment of herpetic keratitis (HK): transporter recognition, tissue stability and antiviral activity.
|
Pharm Res
|
2013
|
0.84
|
41
|
Identification and functional characterization of riboflavin transporter in human-derived retinoblastoma cell line (Y-79): mechanisms of cellular uptake and translocation.
|
J Ocul Pharmacol Ther
|
2005
|
0.83
|
42
|
Activity of a sodium-dependent vitamin C transporter (SVCT) in MDCK-MDR1 cells and mechanism of ascorbate uptake.
|
Int J Pharm
|
2008
|
0.83
|
43
|
Honokiol inhibits HIF pathway and hypoxia-induced expression of histone lysine demethylases.
|
Biochem Biophys Res Commun
|
2012
|
0.83
|
44
|
Identification and functional expression of a carrier-mediated riboflavin transport system on rabbit corneal epithelium.
|
Curr Eye Res
|
2006
|
0.83
|
45
|
Molecular and functional characterization of riboflavin specific transport system in rat brain capillary endothelial cells.
|
Brain Res
|
2012
|
0.83
|
46
|
Biotin uptake by T47D breast cancer cells: functional and molecular evidence of sodium-dependent multivitamin transporter (SMVT).
|
Int J Pharm
|
2012
|
0.83
|
47
|
Interaction Studies of Resolvin E1 Analog (RX-10045) with Efflux Transporters.
|
J Ocul Pharmacol Ther
|
2015
|
0.82
|
48
|
Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin.
|
Int J Pharm
|
2011
|
0.82
|
49
|
Role of OATP-1B1 and/or OATP-1B3 in hepatic disposition of tyrosine kinase inhibitors.
|
Drug Metabol Drug Interact
|
2014
|
0.82
|
50
|
Biotin uptake and cellular translocation in human derived retinoblastoma cell line (Y-79): a role of hSMVT system.
|
Int J Pharm
|
2006
|
0.82
|
51
|
Functional characterization and molecular identification of vitamin C transporter (SVCT2) in human corneal epithelial (HCEC) and retinal pigment epithelial (D407) cells.
|
Curr Eye Res
|
2014
|
0.81
|
52
|
Hypoxia induced expression of histone lysine demethylases: implications in oxygen-dependent retinal neovascular diseases.
|
Biochem Biophys Res Commun
|
2011
|
0.81
|
53
|
Functional and molecular aspects of biotin uptake via SMVT in human corneal epithelial (HCEC) and retinal pigment epithelial (D407) cells.
|
AAPS J
|
2012
|
0.81
|
54
|
Carrier mediated uptake of L-tyrosine and its competitive inhibition by model tyrosine linked compounds in a rabbit corneal cell line (SIRC)--strategy for the design of transporter/receptor targeted prodrugs.
|
Int J Pharm
|
2002
|
0.81
|
55
|
Novel pentablock copolymer-based nanoparticulate systems for sustained protein delivery.
|
AAPS PharmSciTech
|
2014
|
0.81
|
56
|
Molecular expression and functional activity of efflux and influx transporters in hypoxia induced retinal pigment epithelial cells.
|
Int J Pharm
|
2013
|
0.80
|
57
|
Novel L-Dopa and dopamine prodrugs containing a 2-phenyl-imidazopyridine moiety.
|
Pharm Res
|
2007
|
0.79
|
58
|
Ocular sustained release nanoparticles containing stereoisomeric dipeptide prodrugs of acyclovir.
|
J Ocul Pharmacol Ther
|
2011
|
0.79
|
59
|
Identification and functional characterization of breast cancer resistance protein in human bronchial epithelial cells (Calu-3).
|
Int J Pharm
|
2009
|
0.79
|
60
|
Influence of overexpression of efflux proteins on the function and gene expression of endogenous peptide transporters in MDR-transfected MDCKII cell lines.
|
Int J Pharm
|
2012
|
0.78
|
61
|
Mechanism of ganciclovir uptake by rabbit retina and human retinal pigmented epithelium cell line ARPE-19.
|
Curr Eye Res
|
2004
|
0.78
|
62
|
Transporter-targeted lipid prodrugs of cyclic cidofovir: a potential approach for the treatment of cytomegalovirus retinitis.
|
J Pharm Sci
|
2012
|
0.78
|
63
|
Inhibition of OATP-1B1 and OATP-1B3 by tyrosine kinase inhibitors.
|
Drug Metabol Drug Interact
|
2014
|
0.78
|
64
|
Functional activity of a monocarboxylate transporter, MCT1, in the human retinal pigmented epithelium cell line, ARPE-19.
|
Mol Pharm
|
2005
|
0.78
|
65
|
Identification and functional characterization of a Na(+)-independent large neutral amino acid transporter (LAT2) on ARPE-19 cells.
|
Int J Pharm
|
2004
|
0.78
|
66
|
Transfected MDCK cell line with enhanced expression of CYP3A4 and P-glycoprotein as a model to study their role in drug transport and metabolism.
|
Mol Pharm
|
2012
|
0.77
|
67
|
Transport of HIV-protease inhibitors across 1 alpha,25di-hydroxy vitamin D3-treated Calu-3 cell monolayers: modulation of P-glycoprotein activity.
|
Pharm Res
|
2002
|
0.76
|
68
|
Role of membrane transporters and metabolizing enzymes in ocular drug delivery.
|
Curr Drug Metab
|
2014
|
0.76
|
69
|
Statistical design for formulation optimization of hydrocortisone butyrate-loaded PLGA nanoparticles.
|
AAPS PharmSciTech
|
2014
|
0.76
|
70
|
Discovery of novel inhibitors for the treatment of glaucoma.
|
Expert Opin Drug Discov
|
2015
|
0.75
|
71
|
Mitochondrial localization of P-glycoprotein and peptide transporters in corneal epithelial cells--novel strategies for intracellular drug targeting.
|
Exp Eye Res
|
2012
|
0.75
|
72
|
Clinically relevant drug-drug interactions between antiretrovirals and antifungals.
|
Expert Opin Drug Metab Toxicol
|
2014
|
0.75
|
73
|
Binary and ternary combinations of anti-HIV protease inhibitors: effect on gene expression and functional activity of CYP3A4 and efflux transporters.
|
Drug Metabol Drug Interact
|
2014
|
0.75
|
74
|
Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells.
|
J Pharm Pharmacol
|
2013
|
0.75
|
75
|
Canine periodontal disease control using a clindamycin hydrochloride gel.
|
J Vet Dent
|
2011
|
0.75
|
76
|
Topical formulation of self-assembled antiviral prodrug nanomicelles for targeted retinal delivery.
|
Mol Pharm
|
2017
|
0.75
|