Published in J Mol Evol on December 06, 2006
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A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling. EMBO J (2002) 2.42
An alignment confidence score capturing robustness to guide tree uncertainty. Mol Biol Evol (2010) 2.39
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Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy. EMBO J (2002) 2.17
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Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy. Proc Natl Acad Sci U S A (2005) 2.00
Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog (2009) 1.94
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A combined empirical and mechanistic codon model. Mol Biol Evol (2006) 1.52
Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal. Proc Natl Acad Sci U S A (2013) 1.51
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The complexity hypothesis revisited: connectivity rather than function constitutes a barrier to horizontal gene transfer. Mol Biol Evol (2010) 1.44
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The conserved carboxy terminus of the capsid domain of human immunodeficiency virus type 1 gag protein is important for virion assembly and release. J Virol (2004) 1.18
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Improving the performance of positive selection inference by filtering unreliable alignment regions. Mol Biol Evol (2011) 1.15
Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity. J Biol Chem (2004) 1.14
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Deep Panning: steps towards probing the IgOme. PLoS One (2012) 1.08
SMARCA2 and other genome-wide supported schizophrenia-associated genes: regulation by REST/NRSF, network organization and primate-specific evolution. Hum Mol Genet (2010) 1.07
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Evolutionary modeling of rate shifts reveals specificity determinants in HIV-1 subtypes. PLoS Comput Biol (2008) 1.05
Inhibition of triple-negative breast cancer models by combinations of antibodies to EGFR. Proc Natl Acad Sci U S A (2013) 1.05
Phosphatidylserine increases IKBKAP levels in familial dysautonomia cells. PLoS One (2010) 0.98
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Evolutionary models accounting for layers of selection in protein-coding genes and their impact on the inference of positive selection. Mol Biol Evol (2011) 0.97
Cell cycle regulation and p53 activation by protein phosphatase 2C alpha. J Biol Chem (2003) 0.96
State-of the art methodologies dictate new standards for phylogenetic analysis. BMC Evol Biol (2013) 0.92
An evolutionary analysis of lateral gene transfer in thymidylate synthase enzymes. Syst Biol (2010) 0.91
Uncovering the co-evolutionary network among prokaryotic genes. Bioinformatics (2012) 0.90
Identification of Legionella pneumophila effectors regulated by the LetAS-RsmYZ-CsrA regulatory cascade, many of which modulate vesicular trafficking. J Bacteriol (2013) 0.90
Native homing endonucleases can target conserved genes in humans and in animal models. Nucleic Acids Res (2011) 0.90
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Tailored cancer immunotherapy using combinations of chemotherapy and a mixture of antibodies against EGF-receptor ligands. Proc Natl Acad Sci U S A (2010) 0.82
Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity. Mol Cancer (2007) 0.82
A machine learning approach to identify hydrogenosomal proteins in Trichomonas vaginalis. Eukaryot Cell (2011) 0.82
Homing endonucleases residing within inteins: evolutionary puzzles awaiting genetic solutions. Biochem Soc Trans (2011) 0.81
Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells. PLoS One (2012) 0.80
Paths of lateral gene transfer of lysyl-aminoacyl-tRNA synthetases with a unique evolutionary transition stage of prokaryotes coding for class I and II varieties by the same organisms. BMC Evol Biol (2006) 0.80
CoPAP: Coevolution of presence-absence patterns. Nucleic Acids Res (2013) 0.80
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An inducible system to study the growth arrest properties of protein phosphatase 2C. Methods Enzymol (2003) 0.77
Phylogeny reconstruction: increasing the accuracy of pairwise distance estimation using Bayesian inference of evolutionary rates. Bioinformatics (2007) 0.76