PubRank

David J Thornton

Author PubWeight™ 46.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Med 2008 4.24
2 Endothelial function in HIV-infected persons. Clin Infect Dis 2006 3.80
3 Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B. Biochem J 2002 2.02
4 Muc5ac: a critical component mediating the rejection of enteric nematodes. J Exp Med 2011 1.88
5 Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? Am J Physiol Lung Cell Mol Physiol 2008 1.55
6 Mucin gene deficiency in mice impairs host resistance to an enteric parasitic infection. Gastroenterology 2010 1.41
7 Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP. Hum Mol Genet 2007 1.35
8 MUC16 is produced in tracheal surface epithelium and submucosal glands and is present in secretions from normal human airway and cultured bronchial epithelial cells. Int J Biochem Cell Biol 2007 1.30
9 MUC5B is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008 1.27
10 Targeted induction of endoplasmic reticulum stress induces cartilage pathology. PLoS Genet 2009 1.21
11 Identification of molecular intermediates in the assembly pathway of the MUC5AC mucin. J Biol Chem 2004 1.20
12 Decreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a matn3 mutation. Hum Mol Genet 2007 1.18
13 Calcium-dependent protein interactions in MUC5B provide reversible cross-links in salivary mucus. J Biol Chem 2003 1.14
14 Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma. Am J Respir Crit Care Med 2009 1.11
15 Collagen XXVII is developmentally regulated and forms thin fibrillar structures distinct from those of classical vertebrate fibrillar collagens. J Biol Chem 2007 1.10
16 An unfolded protein response is the initial cellular response to the expression of mutant matrilin-3 in a mouse model of multiple epiphyseal dysplasia. Cell Stress Chaperones 2010 1.03
17 Particle tracking microrheology of purified gastrointestinal mucins. Biopolymers 2014 1.02
18 Proteomic analysis of mouse growth plate cartilage. Proteomics 2006 1.01
19 Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier. PLoS Negl Trop Dis 2012 0.99
20 Concentrated solutions of salivary MUC5B mucin do not replicate the gel-forming properties of saliva. Biochem J 2002 0.99
21 Structural and functional characterization of recombinant matrilin-3 A-domain and implications for human genetic bone diseases. J Biol Chem 2007 0.96
22 Proteomic analysis of polymeric salivary mucins: no evidence for MUC19 in human saliva. Biochem J 2008 0.94
23 A new role for mucins in immunity: insights from gastrointestinal nematode infection. Int J Biochem Cell Biol 2012 0.93
24 Electronic memorandum decreases unnecessary antimicrobial use for asymptomatic bacteriuria and culture-negative pyuria. Infect Control Hosp Epidemiol 2011 0.90
25 Utility of cystatin C to monitor renal function in Duchenne muscular dystrophy. Muscle Nerve 2009 0.89
26 Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii. BMC Microbiol 2009 0.88
27 A novel role for Gtb1p in glucose trimming of N-linked glycans. Glycobiology 2009 0.87
28 A secretory cell type develops alongside multiciliated cells, ionocytes and goblet cells, and provides a protective, anti-infective function in the frog embryonic mucociliary epidermis. Development 2014 0.86
29 Muc5b and Muc5ac are the major oligomeric mucins in equine airway mucus. Am J Physiol Lung Cell Mol Physiol 2007 0.85
30 Partial characterisation of high-molecular weight glycoconjugates in the trail mucus of the freshwater pond snail Lymnaea stagnalis. Comp Biochem Physiol B Biochem Mol Biol 2004 0.82
31 Expression and secretion of Aspergillus fumigatus proteases are regulated in response to different protein substrates. Fungal Biol 2012 0.81
32 Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures. Biol Open 2013 0.80
33 Desulfurization of mucin by Pseudomonas aeruginosa: influence of sulfate in the lungs of cystic fibrosis patients. J Med Microbiol 2012 0.80
34 TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells. Exp Lung Res 2012 0.78
35 A combined small-angle X-ray and neutron scattering study of the structure of purified soluble gastrointestinal mucins. Biopolymers 2014 0.78
36 Loss of matrilin 1 does not exacerbate the skeletal phenotype in a mouse model of multiple epiphyseal dysplasia caused by a Matn3 V194D mutation. Arthritis Rheum 2012 0.78
37 Gel-forming and cell-associated mucins: preparation for structural and functional studies. Methods Mol Biol 2012 0.77
38 Muc5b is the major polymeric mucin in mucus from thoroughbred horses with and without airway mucus accumulation. PLoS One 2011 0.77
39 Detecting, visualising, and quantifying mucins. Methods Mol Biol 2012 0.77
40 The alternatively spliced type III connecting segment of fibronectin is a zinc-binding module. Matrix Biol 2007 0.75
41 A reproducible protocol for analysis of the proteome of Trypanosoma brucei by 2-dimensional gel electrophoresis. Mol Biochem Parasitol 2003 0.75
42 The expression of mucin genes and the presence of mucin gene products in the equine endometrium. Res Vet Sci 2013 0.75